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Original Article

The Laser Doppler: A Non-invasive Measure of Cochlear Blood Flow

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Pages 403-412 | Published online: 08 Jul 2009

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (11)

Mattis Bertlich, Fritz Ihler, Kariem Sharaf, Bernhard G. Weiss, Michael Strupp & Martin Canis. (2014) Betahistine metabolites, Aminoethylpyridine, and Hydroxyethylpyridine increase cochlear blood flow in guinea pigs in vivo. International Journal of Audiology 53:10, pages 753-759.
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R. Albera, V. Ferrero, A. Canale, L. De Siena, F. Pallavicino & L. Poli. (2003) Cochlear Blood Flow Modifications Induced by Anaesthetic Drugs in Middle Ear Surgery: Comparison Between Sevoflurane and Propofol. Acta Oto-Laryngologica 123:7, pages 812-816.
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Timothy T. K. Jung, Allen L. Hwang, Stanley K. Miller, Chung-Ku Rhee & Yong-Soo Park. (1995) Effect of Leukotriene Inhibitor on Cochlear Blood Flow in Salicylate Ototoxicity. Acta Oto-Laryngologica 115:2, pages 251-254.
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H. A. Dengerink, F. L. Lindgren & A. Axelsson. (1992) The Interaction of Smoking and Noise on Temporary Threshold Shifts. Acta Oto-Laryngologica 112:6, pages 932-938.
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G. M. McLaren, H. A. Dengerink, P. A. Hellstrom & J. W. Wright. (1991) Effects of Perilymph Volume Adjustments on Cochlear Blood Flow in the Guinea Pig. Acta Oto-Laryngologica 111:1, pages 94-100.
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W. S. Quirk, H. A. Dengerink, M. J. Bademian & J. W. Wright. (1990) Mannitol and Dextran Increase Cochlear Blood Flow in Normotensive and Spontaneously Hypertensive Rats. Acta Oto-Laryngologica 109:5-6, pages 383-388.
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F. Lindgren, H. Dengerink & A. Axelsson. (1989) The Influence of Carbogen on Susceptibility to TTS. Scandinavian Audiology 18:1, pages 47-52.
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M. Hasegawa, K. Yokoyama, N. Kobayashi, A. Okamoto, T. Tamura & I. Watanabe. (1989) Blood Pressure and Cochlear Blood Flow in the Guinea Pig. Acta Oto-Laryngologica 107:5-6, pages 413-416.
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K. Yokoyama, M. Hasegawa, N. Kobayashi, T. Tamura & M. Hasegawa. (1988) Observations on cochlear blood flow using the laser doppler method in guinea pigs. Acta Oto-Laryngologica 106:3-4, pages 192-199.
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Harold A. Dengerink, Alf Axelsson, John Wright & Josef Miller. (1987) Histological Measures of Cochlear Blood Flow A Validation Study. Acta Oto-Laryngologica 104:1-2, pages 113-118.
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M. Sakagami, M. Sano, T. Harada, T. Kubo, T. Matsunaga & S. Sakai. (1986) Morphological Study of Blood-Labyrinth Barrier in the Vestibular Organs under Normal and Experimental Acute Hypertensive and Acute Hypotensive Conditions. Acta Oto-Laryngologica 101:3-4, pages 165-171.
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Articles from other publishers (40)

Hyun Mi Ju, Sun Hee Lee, Tae Hoon Kong, Seung-Hae Kwon, Jin Sil Choi & Young Joon Seo. (2017) Usefulness of Intravital Multiphoton Microscopy in Visualizing Study of Mouse Cochlea and Volume Changes in the Scala Media. Frontiers in Neurology 8.
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Friedrich Ihler, Mattis Bertlich, Bernhard Weiss, Steffen Dietzel & Martin Canis. (2015) Two-Photon Microscopy Allows Imaging and Characterization of Cochlear Microvasculature In Vivo. BioMed Research International 2015, pages 1-8.
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Fritz Ihler, Mattis Bertlich, Kariem Sharaf, Sebastian Strieth, Michael Strupp & Martin Canis. (2012) Betahistine Exerts a Dose-Dependent Effect on Cochlear Stria Vascularis Blood Flow in Guinea Pigs In Vivo. PLoS ONE 7:6, pages e39086.
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Martin Canis, Warangkana Arpornchayanon, Catalina Messmer, Markus Suckfuell, Bernhard Olzowy & Sebastian Strieth. (2009) An animal model for the analysis of cochlear blood flood disturbance and hearing threshold in vivo. European Archives of Oto-Rhino-Laryngology 267:2, pages 197-203.
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Niloy Choudhury, Fangyi Chen, Xiaorui Shi, Alfred L Nuttall & Ruikang K Wang. (2010) Volumetric Imaging of Blood Flow Within Cochlea in Gerbil In Vivo . IEEE Journal of Selected Topics in Quantum Electronics 16:3, pages 524-529.
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Ashkan Monfared, Nikolas H Blevins, Eunice L. M Cheung, Juergen C Jung, Gerald Popelka & Mark J Schnitzer. (2006) In Vivo Imaging of Mammalian Cochlear Blood Flow Using Fluorescence Microendoscopy. Otology & Neurotology 27:2, pages 144-152.
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T.A Hamilton, R.K Handa, J.W Harding & J.W Wright. (2001) A role for the angiotensin IV/AT4 system in mediating natriuresis in the rat. Peptides 22:6, pages 935-944.
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Sharon Freeman, Jean-Yves Sichel & Haim Sohmer. (2000) Bone conduction experiments in animals – evidence for a non-osseous mechanism. Hearing Research 146:1-2, pages 72-80.
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A. Okamoto Ugnell & P.Å. Öberg. (1997) The optical properties of the cochlear bone. Medical Engineering & Physics 19:7, pages 630-636.
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Esa A. Laurikainen, Tianying Ren, Josef M. Miller, Alfred L. Nuttall & Wayne S. Quirk. (1997) The tonic sympathetic input to the cochlear vasculature in guinea pig. Hearing Research 105:1-2, pages 141-145.
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J.W. Wright & J.W. Harding. (1994) Brain angiotensin receptor subtypes in the control of physiological and behavioral responses. Neuroscience & Biobehavioral Reviews 18:1, pages 21-53.
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C. S. Degoute, C. Dubreuil, M. J. Ray, J. Guitton, M. Manchon, V. Banssillon & J. L. Saumet. (1994) Effects of posture, hypotension and locally applied vasoconstriction on the middle ear microcirculation in anaesthetized humans. European Journal of Applied Physiology and Occupational Physiology 69:5, pages 414-420.
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G.M. McLaren, W.S. Quirk, E. Laurikainen, J.K.M. Coleman, M.D. Seidman, H.A. Dengerink, A.L. Nuttall, J.M. Miller & J.W. Wright. (1993) Substance P increases cochlear blood flow without changing cochlear electrophysiology in rats. Hearing Research 71:1-2, pages 183-189.
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Tianying Ren, Esa Laurikainen, Wayne S. Quirk, Josef M. Miller & Alfred L. Nuttall. (2016) Effects of Stellate Ganglion Stimulation on Bilateral Cochlear Blood Flow. Annals of Otology, Rhinology & Laryngology 102:5, pages 378-384.
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David L. Baldwin, Josef M. Miller, K. Agnetha Ohlsén & Alfred L. Nuttall. (2016) Cochlear Blood Flow and Microvascular Resistance Changes in Response to Hypertonic Glycerol, Urea, and Mannitol Infusions. Annals of Otology, Rhinology & Laryngology 101:2, pages 168-175.
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J. K. M. Coleman, H. A. Dengerink & John W. Wright. (1991) Effects of Hydroxyethyl Starch, Nimodipine, and Propylene Glycol on Cochlear Blood Flow. Otolaryngology–Head and Neck Surgery 105:6, pages 840-844.
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G.M. McLaren, J.K.M. Coleman, W.S. Quirk, H.A. Dengerink & J.W. Wright. (1991) The influence of intra-arterial infusion of arginine vasopressin on cochlear blood flow in the rat. Hearing Research 55:1, pages 1-8.
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Josef M. Miller, J. Suonpää, Goran Bredberg, Bo Lindström, Reidar Grenman & Anne Didier. (2016) Measurement of Human Cochlear Blood Flow. Annals of Otology, Rhinology & Laryngology 100:1, pages 44-53.
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M. Kawakami, K. Makimoto, O. Noi & H. Takahashi. (1991) Relationship between cochlear blood flow and perilymphatic oxygen tension. European Archives of Oto-Rhino-Laryngology 248:8, pages 465-470.
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A.J Flynn, H.A Dengerink & J.W Wright. (1990) Androgenic effects on angiotensin II-induced blood pressure and cochlear blood flow changes in rats. Hearing Research 50:1-2, pages 119-125.
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J.K.M. Coleman, W.S. Quirk, H.A. Dengerink & J.W. Wright. (1990) Pentoxifylline increases cochlear blood flow while decreasing blood pressure in guinea pigs. Hearing Research 47:1-2, pages 169-174.
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Josef M. Miller & Alfred L. Nuttall. 1990. Laser-Doppler Blood Flowmetry. Laser-Doppler Blood Flowmetry 319 347 .
Jiri Prazma, Vincent N. Carrasco, C.Gaelyn Garrett & Harold C. Pillsbury. (1989) Measurement of cochlear blood flow: Intravital fluorescence microscopy. Hearing Research 42:2-3, pages 229-236.
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M. J. LaRouere, J. S. Sillman, A. L. Nuttall & J. M. Miller. (2016) A Comparison of Laser Doppler and Intravital Microscopic Measures of Cochlear Blood Flow. Otolaryngology–Head and Neck Surgery 101:3, pages 375-384.
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A.J Flynn, W.S Quirk, H.A Dengerink & J.W Wright. (1989) The effects of intracerebroventricularly administered angiotensin II on blood pressure and cochlear blood flow in rats and guinea pigs. Hearing Research 41:2-3, pages 249-254.
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W.S. Quirk, H.A. Dengerink, J.K. Coleman & J.W. Wright. (1989) Cochlear blood flow autoregulation in Wistar-Kyoto rats. Hearing Research 41:1, pages 53-60.
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W.S Quirk, H.A Dengerink, J.W Harding, M.J Bademian, S.J Swanson & J.W Wright. (1989) Autoregulation of cochlear blood flow in normotensive and spontaneously hypertensive rats following intracerebroventricularly mediated adjustment of blood pressure. Hearing Research 38:1-2, pages 119-123.
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T. Tamura, A. Okamoto, N. Kobayashi, K. Yokoyama, M. Hasegawa & T. Togawa. (1989) Evaluation of cochlear blood flow measurement by laser Doppler flowmetry. Evaluation of cochlear blood flow measurement by laser Doppler flowmetry.
Josef M. Miller & Hal Dengerink. (1988) Control of inner ear blood flow. American Journal of Otolaryngology 9:6, pages 302-316.
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Alfred L. Nuttall. (1988) Cochlear blood flow: Measurement techniques. American Journal of Otolaryngology 9:6, pages 291-301.
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W.S Quirk, H.A Dengerink, M.J Bademian, K.W Hall & J.W Wright. (1988) The effects of pentoxifylline on cochlear blood flow in normotensive and spontaneously hypertensive rats. Hearing Research 36:2-3, pages 175-180.
Crossref
Alfred L. Nuttall, Elisabeth Hultcrantz, Hans-Christian Larsen & Clarence Angelborg. (1988) Cochlear blood flow increases after systemic hemodilution: Comparison of simultaneous laser doppler flowmetry and radioactive microsphere measurements. Hearing Research 34:3, pages 215-223.
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A.J Flynn, H.A Dengerink & J.W Wright. (1988) Blood pressure in resting, anesthetized and noise-exposed guinea pigs. Hearing Research 34:2, pages 201-205.
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Wayne S. Quirk, John W. Wright, Harold A. Dengerink & Josef M. Miller. (1988) Angiotensin II-induced changes in cochlear blood flow and blood pressure in normotensive and spontaneously hypertensive rats. Hearing Research 33:2, pages 129-135.
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Jonathon S. Sillman, Michael J. Larouere, Alfred L. Nuttall, Merle Lawrence & Josef M. Miller. (2016) Recent Advances in Cochlear Blood Flow Measurements. Annals of Otology, Rhinology & Laryngology 97:1, pages 1-8.
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Elisabeth Hultcrantz & Alfred L. Nuttall. (1987) Effect of hemodilution on cochlear blood flow measured by laser-doppler flowmetry. American Journal of Otolaryngology 8:1, pages 16-22.
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Laurence D. Fechter, Peter R. Thorne & Alfred L. Nuttall. (1987) Effects of carbon monoxide on cochlear electrophysiology and blood flow. Hearing Research 27:1, pages 37-45.
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P.R. Thorne & A.L. Nuttall. (1987) Laser doppler measurements of cochlear blood flow during loud sound exposure in the guinea pig. Hearing Research 27:1, pages 1-10.
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Alfred L. Nuttall. (1987) Techniques for the observation and measurement of red blood cell velocity in vessels of the guinea pig cochlea. Hearing Research 27:2, pages 111-119.
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John W. Wright, Harold A. Dengerink, Josef M. Miller & Paul C. Goodwin. (1985) Potential role of angiotensin II in noise-induced increases in inner ear blood flow. Hearing Research 17:1, pages 41-46.
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