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Original Article

The Nasopharyngeal Microflora of Otitis-Prone Children, With Emphasis on H. Influenzae

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Pages 117-126 | Published online: 08 Jul 2009

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Read on this site (13)

Karin Lindberg, Rolf Gustafson, Anders Samuelson, Britta Rynnel-Dagöö. (2001) Impact of IgG Replacement Therapy and Antibiotic Treatment on the Colonization of Non-encapsulated Haemophilus Influenzae in the Nasopharynx in Patients with Hypogammaglobulinaemia. Scandinavian Journal of Infectious Diseases 33:12, pages 904-908.
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Britta Rynnel-dagöö. (1997) Are There Microbiological Markers to Predict Recurrent Acute Otitis Media?. Acta Oto-Laryngologica 117:sup529, pages 19-21.
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Karin Magnuson, Ann Hermansson, Åsa Melhus & Sten Hellström. (1997) The Tympanic Membrane and Middle Ear Mucosa during Non-typeable Haemophilus influenzae and Haemophilus influenzae type b Acute Otitis Media: A Study in the Rat. Acta Oto-Laryngologica 117:3, pages 396-405.
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Joachim Forsgren, Anders Samuelson, Silvia Borrelli, Birger Christensson, Jon Jonasson & Alf A. Lindberg. (1996) Persistence of Nontypeable Haemophilus influenzae in Adenoid Macrophages: A Putative Colonization Mechanism. Acta Oto-Laryngologica 116:5, pages 766-773.
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Joachim Forsgren, Anders Samuelson, Alf Lindberg & Britta Rynnel-dagöö. (1993) Quantitative Bacterial Culture from Adenoid Lymphatic Tissue with Special Reference to Haemophilus influenzae Age-associated Changes. Acta Oto-Laryngologica 113:5, pages 668-672.
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F. Jørgensen, B. Andersson, S. Larsson & O. Nylén. (1992) Nasopharyngeal Bacterial Flora in Otitis Prone Children Treated with Immunoglobulin. Acta Oto-Laryngologica 112:3, pages 530-538.
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Anders Samuelson, Anders Freud & Britta Rynnel-dagöö. (1991) Treatment Failure in Otitis-prone Children with Prophylactic Tympanostomy Tubes Is Correlated with Nasopharyngeal Haemophilus influenzae Colonization. Acta Oto-Laryngologica 111:6, pages 1090-1096.
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Lars-Eric Stenfors & Simo Räisänen. (1990) Occurrence of middle ear pathogens in the nasopharynx of young individuals: A quantitative study in four age groups. Acta Oto-Laryngologica 109:1-2, pages 142-148.
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Lars-Eric Stenfors & Simo Räisänen. (1989) Colonization of Middle Ear Pathogens in the Nasopharyngeal Opening of the Eustachian Tube during Secretory Otitis Media. Acta Oto-Laryngologica 107:1-2, pages 104-110.
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Lars-Eric Stenfors & Simo Räisänen. (1989) The Bacterial Flora of the Nasopharynx, with Special Reference to Middle Ear Pathogens: A Quantitative Study in Twenty Children. Acta Oto-Laryngologica 108:1-2, pages 122-125.
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Chr. Hjort Sørensen, Leif P. Andersen, Mirko Tos, Jens Thomsen & Sven Holm-Jensen. (1988) Nasopharyngeal Bacteriology and Secretory Otitis Media in Young Children. Acta Oto-Laryngologica 105:1-2, pages 126-131.
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Magnus Thore & MÄRta Lidén. (1987) Relapse of Acute Purulent Otitis Media: Antibiotic Sensitivities of Nasopharyngeal Pathogens. Scandinavian Journal of Infectious Diseases 19:3, pages 315-323.
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Anders Freijd, Vivi-Anne Oxelius & Britta Rynnel-Dagöö. (1985) A Prospective Study Demonstrating an Association between Plasma IgG2 Concentrations and Susceptibility to Otitis Media in Children. Scandinavian Journal of Infectious Diseases 17:1, pages 115-120.
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Benjamin C. Hunt, Xin Xu, Amit Gaggar & W. Edward Swords. (2022) Nontypeable Haemophilus influenzae Redox Recycling of Protein Thiols Promotes Resistance to Oxidative Killing and Bacterial Survival in Biofilms in a Smoke-Related Infection Model. mSphere 7:1.
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Itzhak Brook. 2009. Rhinology and Facial Plastic Surgery. Rhinology and Facial Plastic Surgery 211 230 .
K LINDBERG, B RYNNEL-DAGÖÖ & K-G SUNDQVIST. (1994) Cytokines in nasopharyngeal secretions; evidence for defective IL-1β production in children with recurrent episodes of acute otitis media. Clinical and Experimental Immunology 97:3, pages 396-402.
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Per Cayé-Thomasen & Mirko Tos. (2004) Eustachian tube gland tissue changes are related to bacterial species in acute otitis media. International Journal of Pediatric Otorhinolaryngology 68:1, pages 101-110.
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Itzhak Brook. (2003) Microbial dynamics of purulent nasopharyngitis in children. International Journal of Pediatric Otorhinolaryngology 67:10, pages 1047-1053.
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PAOLA MARCHISIO, LAURA CLAUT, ALESSANDRO ROGNONI, SUSANNA ESPOSITO, DESIDERIO PASSALI, LUISA BELLUSSI, LORENZO DRAGO, GIANNI POZZI, STEFANIA MANNELLI, GIANCARLO SCHITO & NICOLA PRINCIPI. (2003) Differences in nasopharyngeal bacterial flora in children with nonsevere recurrent acute otitis media and chronic otitis media with effusion: implications for management. Pediatric Infectious Disease Journal 22:3, pages 262-268.
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Per Cayé-Thomasen & Mirko Tos. (2002) Histopathologic differences due to bacterial species in acute otitis media. International Journal of Pediatric Otorhinolaryngology 63:2, pages 99-110.
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PER CAYÉ‐THOMASEN. (2011) Histopathology of experimental acute otitis media caused by various bacteria. APMIS 109:S104, pages 5-35.
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Britta Rynnel-Dagöö & Karin Ågren. (2000) The nasopharynx and the middle ear. Inflammatory reactions in middle ear disease. Vaccine 19, pages S26-S31.
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I Dhooge, M Vaneechoutte, G Claeys, G Verschraegen & P Van Cauwenberge. (2000) Turnover of Haemophilus influenzae isolates in otitis-prone children. International Journal of Pediatric Otorhinolaryngology 54:1, pages 7-12.
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Itzhak Brook & Alan E. Gober. (2016) Dynamics of nasopharyngitis in children. Otolaryngology–Head and Neck Surgery 122:5, pages 696-700.
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Itzhak Brook, Alan E. Gober & Alan E. Gober. (2016) Dynamics of Nasopharyngitis in Children. Otolaryngology–Head and Neck Surgery 122:5, pages 696-700.
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Ingeborg Dhooge, Dominique Van Damme, Mario Vaneechoutte, Geert Claeys, Gerda Verschraegen & Paul Van Cauwenberge. (1999) Role of nasopharyngeal bacterial flora in the evaluation of recurrent middle ear infections in children. Clinical Microbiology and Infection 5:9, pages 530-534.
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Lauren O. Bakaletz, Bobbie-Jo Kennedy, Laura A. Novotny, Guy Duquesne, Joe Cohen & Yves Lobet. (1999) Protection against Development of Otitis Media Induced by Nontypeable Haemophilus influenzae by Both Active and Passive Immunization in a Chinchilla Model of Virus-Bacterium Superinfection . Infection and Immunity 67:6, pages 2746-2762.
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Christian Hjort SørensenKirsten Brygge. (1998) Mucosal Immunity and Bacteriology of the Eustachian Tube. Ear, Nose & Throat Journal 77:9, pages 748-761.
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Yan-ping Yang, Sheena M. Loosmore, Brian J. Underdown & Michel H. Klein. (1998) Nasopharyngeal Colonization with Nontypeable Haemophilus influenzae in Chinchillas . Infection and Immunity 66:5, pages 1973-1980.
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B Gardlund, D Rimeika, B Wedelin & J Laska. (2007) Preoperative bacterial colonization of the upper airways does not predict postoperative airway infection in children. Acta Paediatrica 87:4, pages 375-377.
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BRITTA RYNNEL-DAGÖÖ, KARIN LINDBERG, ANDERS SAMULESON, STEN BLOMBERG & JOACHIM FORSGREN. (1997) The Immunology of The Host-Parasite Relationship In the Nasopharynx. Annals of the New York Academy of Sciences 830:1 Immunologic D, pages 32-48.
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Katherine A Holmes & Lauren O Bakaletz. (1997) Adherence of non-typeableHaemophilus influenzaepromotes reorganization of the actin cytoskeleton in human or chinchilla epithelial cellsin vitro. Microbial Pathogenesis 23:3, pages 157-166.
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Thomas E. Linder, Hans-Peter Marder & Jürg Munzinger. (2016) Role of Adenoids in the Pathogenesis of Otitis Media: A Bacteriologic and Immunohistochemical Analysis. Annals of Otology, Rhinology & Laryngology 106:8, pages 619-623.
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Joel M. BernsteinPaul M. BronsonMark E. Wilson. (2016) Immunoglobulin G Subclass Response to Major outer Membrane Proteins of Nontypable Haemophilus Influenzae in Children with Acute Otitis Media . Otolaryngology–Head and Neck Surgery 116:3, pages 363-371.
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T UeyamaY KuronoK ShirabeM TakeshitaG Mogi. (1995) High incidence of Haemophilus influenzae in nasopharyngeal secretions and middle ear effusions as detected by PCR. Journal of Clinical Microbiology 33:7, pages 1835-1838.
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Pekka H. Karma, Lauren O. Bakaletz, G. Scott Giebink, Goro Mogi & Britta Rynnel-Dagöö. (1995) Immunological aspects of otitis media: present views on possibilities of immunoprophylaxis of acute otitis media in infants and children. International Journal of Pediatric Otorhinolaryngology 32, pages S127-S134.
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Jacob Sadé. (2007) The nasopharynx, eustachian tube and otitis media. The Journal of Laryngology & Otology 108:2, pages 95-100.
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Yasuaki Harabuchi, Howard Faden, Noboru Yamanaka, Linda Duffy, Judy Wolf & Deborah Krystofik. (1994) Human milk secretory IgA antibody to nontypeable Haemophilus influenzae: Possible protective effects against nasopharyngeal colonization. The Journal of Pediatrics 124:2, pages 193-198.
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Alison Heald, Raymond Auckenthaler, Francois Borst, Olca Delaspre, Daniel Cermann, Lukas Matter, Laurent Kaiser & Hans Stalder. (1993) Adult bacterial nasopharyngitis. Journal of General Internal Medicine 8:12, pages 667-673.
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Joel M. Bernstein, Howard S. Faden & Pearay L. Ogra. (1991) Nasopharyngeal Colonization by Nontypeable Hemophilus Influenzae in Children: The Effect of Serum Bactericidal Antibody . Otolaryngology–Head and Neck Surgery 105:3, pages 406-410.
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Howard Faden, Linda Brodsky, Mary Jane Waz, John Stanievich, Joel M. Bernstein & Pearay L. Ogra. (2016) Nasopharyngeal Flora in the First Three Years of Life in Normal and Otitis-Prone Children. Annals of Otology, Rhinology & Laryngology 100:8, pages 612-615.
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KIM Kristensen. (1990) Carriage and antibiotic susceptibility of Haemophilus influenzae type b and non b in Danish day-care attendees . APMIS 98:1-6, pages 50-52.
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K. PRELLNER, J.H. BRACONIER & A.G. SJøHOLM. (2009) COMBINED IgG2, IgG4 AND IgA DEFICIENCY: LOW C1Q CONCENTRATIONS AND THE PRESENCE OF EXCESS C1R AND C1S IN AN ADULT PATIENT WITH RECURRENT PNEUMOCOCCAL INFECTIONS. Acta Pathologica Microbiologica Scandinavica Series C: Immunology 93C:1-6, pages 257-263.
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Anders Freijd, Vivi-Anne Oxelius & Britta Rynnel-Dagöö. (2015) A Prospective Study Demonstrating an Association between Plasma IgG2 Concentrations and Susceptibility to Otitis Media in Children. Archives Internationales de Physiologie 17:1, pages 115-120.
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D. Kuklinska & M. Kilian. (1984) Relative proportions ofHaemophilus species in the throat of healthy children and adults. European Journal of Clinical Microbiology 3:3, pages 249-252.
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