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Acta Oto-Laryngologica Volume 113, 1993 - Issue 2
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Original Article

Effects of Free Radicals on the Intracellular Calcium Concentration in the Isolated Outer Hair Cell of the Guinea Pig Cochlea

K. Ikeda Department of Otolaryngology, Laboratory of Cell Physiology and Biology, Tohoku University School of Medicine, Sendai, 980, Japan
,
H. Sunose Department of Otolaryngology, Laboratory of Cell Physiology and Biology, Tohoku University School of Medicine, Sendai, 980, Japan
&
T. Takasaka Department of Otolaryngology, Laboratory of Cell Physiology and Biology, Tohoku University School of Medicine, Sendai, 980, Japan
Pages 137-141 | Received 16 Oct 1992, Accepted 12 Dec 1992, Published online: 08 Jul 2009

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Kyle E. Rarey & Xiaofei Yao. (1996) Localization of Cu/Zn-SOD and Mn-SOD in the Rat Cochlea. Acta Oto-Laryngologica 116:6, pages 833-835.
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Articles from other publishers (47)

Winston J. T. Tan & Srdjan M. Vlajkovic. (2023) Molecular Characteristics of Cisplatin-Induced Ototoxicity and Therapeutic Interventions. International Journal of Molecular Sciences 24:22, pages 16545.
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Megumi Kishimoto-Urata, Shinji Urata, Chisato Fujimoto & Tatsuya Yamasoba. (2022) Role of Oxidative Stress and Antioxidants in Acquired Inner Ear Disorders. Antioxidants 11:8, pages 1469.
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Peipei Li, Ziyi Liu, Jinpeng Wang, Xiuli Bi, Yu Xiao, Ruifeng Qiao, Xuanchen Zhou, Siwei Guo, Peifeng Wan, Miao Chang, Guodong Hong, Zhangsuo Liu, Xia Ming, Jiangang Gao & Xiaolong Fu. (2022) Gstm1/Gstt1 is essential for reducing cisplatin ototoxicity in CBA/CaJ mice. The FASEB Journal 36:6.
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S. Scott Sutton, Joseph Magagnoli, Tammy H. Cummings & James W. Hardin. (2022) Calcium Channel Blockers and the Risk of Sensorineural Hearing Loss. Otology & Neurotology 43:2, pages e140-e147.
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Dehong Yu, Jiayi Gu, Yuming Chen, Wen Kang, Xueling Wang & Hao Wu. (2020) Current Strategies to Combat Cisplatin-Induced Ototoxicity. Frontiers in Pharmacology 11.
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James G. Naples, Michael J. Ruckenstein, Jarnail Singh, Brandon C. Cox & Daqing Li. (2020) Intratympanic Diltiazem-Chitosan Hydrogel as an Otoprotectant Against Cisplatin-Induced Ototoxicity in a Mouse Model. Otology & Neurotology 41:1, pages 115-122.
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Shou-Sen Hu, Shi-Zhong Cai & Xiang-Zhen Kong. (2019) Chronic Lead Exposure Results in Auditory Deficits and Disruption of Hair Cells in Postweaning Rats. Oxidative Medicine and Cellular Longevity 2019, pages 1-8.
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M.E. Cosenza & A.W. Hayes. 2018. Comprehensive Toxicology. Comprehensive Toxicology 338 360 .
Sandeep Sheth, Debashree Mukherjea, Leonard P. Rybak & Vickram Ramkumar. 2018. Inflammatory Mechanisms in Mediating Hearing Loss. Inflammatory Mechanisms in Mediating Hearing Loss 149 164 .
James G. Naples. (2017) Calcium-channel blockers as therapeutic agents for acquired sensorineural hearing loss. Medical Hypotheses 104, pages 121-125.
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James G. Naples & Kourosh Parham. (2015) Cisplatin‐Induced Ototoxicity and the Effects of Intratympanic Diltiazem in a Mouse Model. Otolaryngology–Head and Neck Surgery 154:1, pages 144-149.
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Jessica Paken, Cyril D. Govender, Mershen Pillay & Vikash Sewram. (2016) Cisplatin-Associated Ototoxicity: A Review for the Health Professional. Journal of Toxicology 2016, pages 1-13.
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Gi Jung Im, Jiwon Chang, Sehee Lee, June Choi, Hak Hyun Jung, Hyung Min Lee, Sung Hoon Ryu, Su Kyoung Park, Jin Hwan Kim & Hyung-Jong Kim. (2015) Protective role of edaravone against cisplatin-induced ototoxicity in an auditory cell line. Hearing Research 330, pages 113-118.
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Takatoshi Karasawa & Peter S. Steyger. (2015) An integrated view of cisplatin-induced nephrotoxicity and ototoxicity. Toxicology Letters 237:3, pages 219-227.
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Angela Callejo, Lara Sedó-Cabezón, Ivan Juan & Jordi Llorens. (2015) Cisplatin-Induced Ototoxicity: Effects, Mechanisms and Protection Strategies. Toxics 3:3, pages 268-293.
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Sherif F. Tadros, Mary D'Souza, Xiaoxia Zhu & Robert D. Frisina. (2014) Gene Expression Changes for Antioxidants Pathways in the Mouse Cochlea: Relations to Age-related Hearing Deficits. PLoS ONE 9:2, pages e90279.
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M S Gonçalves, A F Silveira, A R Teixeira & M A Hyppolito. (2013) Mechanisms of cisplatin ototoxicity: theoretical review. The Journal of Laryngology & Otology 127:6, pages 536-541.
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Leonard P. Rybak, Debashree Mukherjea, Sarvesh Jajoo, Tejbeer Kaur & Vickram Ramkumar. (2012) siRNA-mediated knock-down of NOX3: therapy for hearing loss?. Cellular and Molecular Life Sciences 69:14, pages 2429-2434.
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B. Pouyatos, L.D. Fechter & L. Linda. 2010. Comprehensive Toxicology. Comprehensive Toxicology 239 262 .
Leonard P Rybak, Debashree Mukherjea, Sarvesh Jajoo & Vickram Ramkumar. (2009) Cisplatin Ototoxicity and Protection: Clinical and Experimental Studies. The Tohoku Journal of Experimental Medicine 219:3, pages 177-186.
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Miguel Ângelo Hyppolito, José Antonio A. Oliveira & Maria Rossato. (2006) Cisplatin ototoxicity and otoprotection with sodium salicylate. European Archives of Oto-Rhino-Laryngology 263:9, pages 798-803.
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Ania G. Pollack, MaryAnne H. Marymont, John A. Kalapurakal, Alan Kepka, Vythialingam Sathiaseelan & James P. Chandler. (2005) Acute neurological complications following gamma knife surgery for vestibular schwannoma. Journal of Neurosurgery 103:3, pages 546-551.
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K. Husain, B. Scott, C. Whitworth & L.P. Rybak. (2004) Time response of carboplatin-induced hearing loss in rat. Hearing Research 191:1-2, pages 110-118.
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Kazim Husain, Craig Whitworth, Stephen Hazelrigg & Leonard Rybak. (2016) Carboplatin-Induced Oxidative Injury in Rat Inferior Colliculus. International Journal of Toxicology 22:5, pages 335-342.
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Umit Tuncel, William J Clerici & Raleigh O Jones. (2002) Differential ototoxicities induced by lead acetate and tetraethyl lead. Hearing Research 166:1-2, pages 113-123.
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Deepa B. Rao, Danny R. Moore, Lester A. Reinke & Laurence D. Fechter. (2001) Free radical generation in the cochlea during combined exposure to noise and carbon monoxide: an electrophysiological and an EPR study. Hearing Research 161:1-2, pages 113-122.
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K. Husain, C. Whitworth, S.M. Somani & L.P. Rybak. (2001) Carboplatin-induced oxidative stress in rat cochlea. Hearing Research 159:1-2, pages 14-22.
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K. Husain, R.B. Scott, C. Whitworth, S.M. Somani & L.P. Rybak. (2001) Dose response of carboplatin-induced hearing loss in rats: antioxidant defense system. Hearing Research 151:1-2, pages 71-78.
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Deepa Rao & Laurence D. Fechter. (2000) Protective Effects of Phenyl-N-tert-butylnitrone on the Potentiation of Noise-Induced Hearing Loss by Carbon Monoxide. Toxicology and Applied Pharmacology 167:2, pages 125-131.
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N. Dehne, J. Lautermann, W.-J.F. ten Cate, U. Rauen & H. de Groot. (2000) In vitro effects of hydrogen peroxide on the cochlear neurosensory epithelium of the guinea pig. Hearing Research 143:1-2, pages 162-170.
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Shaheen Ara Alam, Katsuhisa Ikeda, Takeshi Oshima, Masaaki Suzuki, Tetsuaki Kawase, Toshihiko Kikuchi & Tomonori Takasaka. (2000) Cisplatin-induced apoptotic cell death in Mongolian gerbil cochlea. Hearing Research 141:1-2, pages 28-38.
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RICHARD KOPKE, KEITH A. ALLEN, DONALD HENDERSON, MICHAEL HOFFER, DOROTHY FRENZ & THOMAS VAN DE WATER. (2006) A Radical Demise: Toxins and Trauma Share Common Pathways in Hair Cell Death. Annals of the New York Academy of Sciences 884:1, pages 171-191.
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T. Oma Hester, Raleigh O. Jones & William J. Clerici. (2016) Protection against Aminoglycoside Otic Drop‐Induced Ototoxicity by a Spin Trap: I. Acute Effects. Otolaryngology–Head and Neck Surgery 119:6, pages 581-587.
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Steven D. Chang, Joseph Poen, Steven L. Hancock, David P. Martin & John R. Adler. (1998) Acute hearing loss following fractionated stereotactic radiosurgery for acoustic neuroma. Journal of Neurosurgery 89:2, pages 321-325.
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Andrew A Jacono, Bohua Hu, Richard D Kopke, Donald Henderson, Thomas R Van De Water & Howard M Steinman. (1998) Changes in cochlear antioxidant enzyme activity after sound conditioning and noise exposure in the chinchilla. Hearing Research 117:1-2, pages 31-38.
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Tatsuya Yamasoba, Alfred L Nuttall, Craig Harris, Yehoash Raphael & Josef M Miller. (1998) Role of glutathione in protection against noise-induced hearing loss. Brain Research 784:1-2, pages 82-90.
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Bo Hua Hu, Xiang Yang Zheng, Sandra L. McFadden, Richard D. Kopke & Donald Henderson. (1997) R-phenylisopropyladenosine attenuates noise-induced hearing loss in the chinchilla. Hearing Research 113:1-2, pages 198-206.
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Leonard P. Rybak, Kazim Husain, L. Evenson, Craig Morris, Craig Whitworth & Satu M. Somani. (2009) Protection by 4‐Methylthiobenzoic Acid Against Cisplatin‐Induced Ototoxicity: Antioxidant System. Pharmacology & Toxicology 81:4, pages 173-179.
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William J. Clerici & Lihua Yang. (1996) Direct effects of intraperilymphatic reactive oxygen species generation on cochlear function. Hearing Research 101:1-2, pages 14-22.
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Xiaofei Yao & Kyle E. Rarey. (1996) Detection and regulation of and MnSOD in rat cochlear tissues. Hearing Research 96:1-2, pages 199-203.
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G. Cornelius. (1996) Different stress factor signals converge at phosphoinositide turnover in Drosophila cells. Journal of Thermal Biology 21:2, pages 85-89.
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Philine Wangemann & Jochen Schacht. 1996. The Cochlea. The Cochlea 130 185 .
Laurence D. Fechter & Ye Liu. (1995) Elevation of intracellular calcium levels in spiral ganglion cells by trimethyltin. Hearing Research 91:1-2, pages 101-109.
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Radhika Ravi, Satu M. Somani & Leonard P. Rybak. (2009) Mechanism of Cisplatin Ototoxicity: Antioxidant System. Pharmacology & Toxicology 76:6, pages 386-394.
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William J. Clerici, Debra L. DiMartino & M.Renuka Prasad. (1995) Direct effects of reactive oxygen species on cochlear outer hair cell shape in vitro. Hearing Research 84:1-2, pages 30-40.
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