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Original Article

Oxygen-Linked Hydrogen Ion Binding of Human Hemoglobin. Effects of Carbon Dioxide and 2,3-Diphosphoglycerate I. Studies on Erythrolysate

Pages 351-360 | Received 22 Feb 1971, Accepted 02 Apr 1971, Published online: 08 Jul 2009

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Marek Mateják, Tomáš Kulhánek & Stanislav Matoušek. (2015) Adair-based hemoglobin equilibrium with oxygen, carbon dioxide and hydrogen ion activity. Scandinavian Journal of Clinical and Laboratory Investigation 75:2, pages 113-120.
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Madeleine Castaing, L. Sibille & J. J. Pocidalo. (1982) The apparent buffer value of human blood for CO2 as a function of temperature. Archives Internationales de Physiologie et de Biochimie 90:4, pages 209-217.
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G. Arturson, L. Garby, M. Robert & B. Zaar. (1974) The Oxygen Dissociation Curve of Normal Human Blood with Special Reference to the Influence of Physiological Effector Ligands. Scandinavian Journal of Clinical and Laboratory Investigation 34:1, pages 9-13.
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O. Siggaard-Andersen & L. Garby. (1973) The Bohr Effect and the Haldane Effect. Scandinavian Journal of Clinical and Laboratory Investigation 31:1, pages 1-8.
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O. Siggaard-Andersen, N. Salling, B. Nörgaard-pedersen & M. Rörth. (1972) Oxygen-Linked Hydrogen Ion Binding of Human Hemoglobin. Effects of Carbon Dioxide and 2,3-Diphosphoglycerate. Scandinavian Journal of Clinical and Laboratory Investigation 29:2, pages 185-193.
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O. Siggaard-Andersen, M. Rörth, B. Nörgaard-Pedersen, O. Sparre Andersen & E. Johansen. (1972) Oxygen-Linked Hydrogen Ion Binding of Human Hemoglobin. Effects of Carbon Dioxide and 2,3-Diphosphoglycerate: IV. Thermodynamical Relationship between the Variables. Scandinavian Journal of Clinical and Laboratory Investigation 29:3, pages 303-320.
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N. Salling & O. Siggaard-Andersen. (1971) Liquid-Junction Potentials between Plasma or Erythrolysate and KCl Solutions. Scandinavian Journal of Clinical and Laboratory Investigation 28:1, pages 33-40.
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O. Siggaard-Andersen & N. Salling. (1971) Oxygen-Linked Hydrogen Ion Binding of Human Hemoglobin. Effects of Carbon Dioxide and 2,3 - Diphosphoglycerate. II. Studies on Whole Blood. Scandinavian Journal of Clinical and Laboratory Investigation 27:4, pages 361-366.
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Hans Malte & Gunnar Lykkeboe. (2018) The Bohr/Haldane effect: a model-based uncovering of the full extent of its impact on O 2 delivery to and CO 2 removal from tissues . Journal of Applied Physiology 125:3, pages 916-922.
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Ranjan K. Dash, Ben Korman & James B. Bassingthwaighte. (2015) Simple accurate mathematical models of blood HbO2 and HbCO2 dissociation curves at varied physiological conditions: evaluation and comparison with other models. European Journal of Applied Physiology 116:1, pages 97-113.
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Stephen E. Rees. (2011) The Intelligent Ventilator (INVENT) project: The role of mathematical models in translating physiological knowledge into clinical practice. Computer Methods and Programs in Biomedicine 104, pages S1-S29.
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Michalis Agrafiotis. (2011) Strong ion reserve: a viewpoint on acid base equilibria and buffering. European Journal of Applied Physiology 111:8, pages 1951-1954.
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Edward A. Westen & Henry D. Prange. (2003) A Reexamination of the Mechanisms Underlying the Arteriovenous Chloride Shift. Physiological and Biochemical Zoology 76:5, pages 603-614.
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H. D. Prange, J. L. ShoemakerJr.Jr., E. A. Westen, D. G. Horstkotte & B. Pinshow. (2001) Physiological consequences of oxygen-dependent chloride binding to hemoglobin. Journal of Applied Physiology 91:1, pages 33-38.
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Medbø, Hanem, Noddeland & Jebens. (2008) Arterio‐venous differences of blood acid–base status and plasma sodium caused by intense bicycling. Acta Physiologica Scandinavica 168:2, pages 311-326.
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G. K. Snyder. 1992. Blood and Tissue Oxygen Carriers. Blood and Tissue Oxygen Carriers 433 453 .
Poul Bennekou. (1988) Protonophore anion permeability of the human red cell membrane determined in the presence of valinomycin. The Journal of Membrane Biology 102:3, pages 225-234.
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Robert A. Klocke. 2011. Comprehensive Physiology. Comprehensive Physiology 173 197 .
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George N Lappennas, James M Colacino & Joseph Bonaventura. 1981. Hemoglobins. Hemoglobins 449 470 .
Mads Dalmark. (1978) Chloride in the human erythrocyte. Progress in Biophysics and Molecular Biology 31, pages 145-164.
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N. Takano & K. Nishikura. (1976) The oxygen-linked hydrogen ion binding (the Haldane coefficient) of bovine hemoglobin. Experientia 32:11, pages 1437-1439.
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Muthuraman Jayalakshmi & Michael Seakins. (1976) The oxygenation of hemoglobin A and hemoglobin S in intact erythrocytes and in aqueous solution. Biochemical Medicine 16:2, pages 104-115.
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Jochen Duhm. (1976) Influence of 2,3-diphosphoglycerate on the buffering properties of human blood. Pfl�gers Archiv European Journal of Physiology 363:1, pages 61-67.
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Wolfgang Barnikol. 1976. Oxygen Transport to Tissue — II. Oxygen Transport to Tissue — II 97 103 .
Arthur A. Messier. (1975) First apparent dissociation constant of carbonic acid, pK1', of plasma and erythrocytes. Respiration Physiology 24:1, pages 51-68.
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J. H. Meldon & L. Garby. (2009) THE BLOOD OXYGEN TRANSPORT SYSTEM A numerical simulation of capillary‐tissue respiratory gas exchange. Acta Medica Scandinavica 197:S578, pages 19-29.
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REINHOLD BENESCH, RUTH E. BENESCH & CHRISTIAN BAUER. 1975. The Red Blood Cell. The Red Blood Cell 825 839 .
Dieter B�ning, Ursula Schweigart, Ulrich Tibes & Bernd Hemmer. (1975) Influences of exercise and endurance training on the oxygen dissociation curve of blood underin vivo andin vitro conditions. European Journal of Applied Physiology and Occupational Physiology 34:1, pages 1-10.
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G. Arturson, L. Garby, B. Wranne & B. Zaar. (2008) Effect of 2, 3‐Diphosphoglycerate on the Oxygen Affinity and on the Proton‐ and Carbamino‐Linked Oxygen Affinity of Hemoglobin in Human Whole Blood. Acta Physiologica Scandinavica 92:3, pages 332-340.
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E. Bursaux, A. Freminet & C. Poyart. (1974) Effects of CO2, and diphosphoglycerate on foetal blood affinity for oxygen. Respiration Physiology 20:2, pages 181-189.
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Christian Bauer. 1974. Reviews of Physiology, Biochemistry and Pharmacology, Volume 70. Reviews of Physiology, Biochemistry and Pharmacology, Volume 70 1 31 .
Danuta T. Zborowska-Sluis & Gerald A. Klassen. (1973) Carbon dioxide mediated glycolysis II. Respiration Physiology 19:2, pages 162-175.
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L. Garby, M. Robert & B. Zaar. (2008) Proton‐ and Carbamino‐linked Oxygen Affinity of Normal Human Blood. Acta Physiologica Scandinavica 84:4, pages 482-492.
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B. Wranne, R. Woodson & J. Detter. 1972. Hemoglobin and Red Cell Structure and Function. Hemoglobin and Red Cell Structure and Function 449 455 .
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