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Original Article

Effect of enalapril on haemoglobin and serum erythropoietin in patients with chronic nephropathy

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Pages 611-618 | Received 22 Sep 1989, Accepted 13 Feb 1990, Published online: 08 Jul 2009

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Aishatu Mohammed Nalado, Johnny N Mahlangu, Bala Waziri, Raquel Duarte, Graham Paget, Gbenga Olorunfemi & Saraladevi Naicker. (2019) Ethnic prevalence of anemia and predictors of anemia among chronic kidney disease patients at a tertiary hospital in Johannesburg, South Africa. International Journal of Nephrology and Renovascular Disease 12, pages 19-32.
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Hong-Jin Zhao, Yan Li, Shan-Mei Liu, Xiang-Guo Sun, Min Li, Yan Hao, Lian-Qun Cui & Ai-Hong Wang. (2016) Effect of calcium channels blockers and inhibitors of the renin-angiotensin system on renal outcomes and mortality in patients suffering from chronic kidney disease: systematic review and meta-analysis. Renal Failure 38:6, pages 849-856.
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Rafia S. Rasu, Tonya Crawford, Harold Manley & Rajesh Balkrishnan. (2008) Treatment and costs associated with anemic chronic kidney disease patients. Current Medical Research and Opinion 24:1, pages 129-137.
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Huifang Cheng & Raymond C Harris. (2006) Potential side effects of renin inhibitors – mechanisms based on comparison with other renin–angiotensin blockers. Expert Opinion on Drug Safety 5:5, pages 631-641.
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J. D. Jensen, H. Eiskjær, B. Madsen, M. Egeblad, C. B. Nielsen & E. B. Pedersen. (1993) Effect of captopril on the renal veno-arterial gradient of erythropoietin and oxygen in unilateral renal artery disease. Scandinavian Journal of Clinical and Laboratory Investigation 53:8, pages 859-865.
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M. C. J. Slagman, S. J. Sinkeler, M. H. Hemmelder, F. Waanders, L. Vogt, H. C. Kluin-Nelemans, G. Navis & G. D. Laverman. (2010) Erythropoietin is reduced by combination of diuretic therapy and RAAS blockade in proteinuric renal patients with preserved renal function. Nephrology Dialysis Transplantation 25:10, pages 3256-3260.
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Demetrios V. Vlahakos, Katerina P. Marathias & Nicolaos E. Madias. (2010) The Role of the Renin-Angiotensin System in the Regulation of Erythropoiesis. American Journal of Kidney Diseases 56:3, pages 558-565.
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Olivier Moranne, Marc Froissart, Jerome Rossert, Cedric Gauci, Jean-Jacques Boffa, Jean Philippe Haymann, Mona Ben M’rad, Christian Jacquot, Pascal Houillier, Benedicte Stengel & Bruno Fouqueray. (2009) Timing of Onset of CKD-Related Metabolic Complications. Journal of the American Society of Nephrology 20:1, pages 164-171.
Crossref
A. Inoue, T. Babazono & Y. Iwamoto. (2008) Effects of the Renin-Angiotensin System Blockade on Hemoglobin Levels in Type 2 Diabetic Patients With Chronic Kidney Disease. American Journal of Hypertension 21:3, pages 317-322.
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J.I. Artero Muñoz, A.B. Marín Floria, C. Cerdán Lanero & Á. Aznar Carbonell. (2007) Anemia por fosinopril. SEMERGEN - Medicina de Familia 33:6, pages 337.
Crossref
R. Ravanan, J. R. Spiro, P. W. Mathieson & R. M. Smith. (2006) Impact of diabetes on haemoglobin levels in renal disease. Diabetologia 50:1, pages 26-31.
Crossref
Vittorino Ripamonti, Vittorio Racca, Maria G. Calvo, Paolo Castiglioni & Maurizio Ferratini. (2006) Angiotensin-Converting Enzyme Inhibitors Slow Recovery From Anemia Following Cardiac Surgery. Chest 130:1, pages 79-84.
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Anumeet Priyadarshi & Joseph I. Shapiro. (2006) HEMATOLOGY: ISSUES IN THE DIALYSIS PATIENT: Erythropoietin Resistance in the Treatment of the Anemia of Chronic Renal Failure. Seminars in Dialysis 19:4, pages 273-278.
Crossref
Kenneth E. BernsteinHong D. XiaoKristen FrenzelPing LiXiao Z. ShenJon W. AdamsSebastien Fuchs. (2005) Six Truisms Concerning ACE and the Renin-Angiotensin System Educed From the Genetic Analysis of Mice . Circulation Research 96:11, pages 1135-1144.
Crossref
Steven Gabardi & Stuart Abramson. (2005) Drug Dosing in Chronic Kidney Disease. Medical Clinics of North America 89:3, pages 649-687.
Crossref
Tarek M. El-Achkar, Suzanne E. Ohmit, Peter A. Mccullough, Errol D. Crook, Wendy W. Brown, Richard Grimm, George L. Bakris, William F. Keane & John M. Flack. (2005) Higher prevalence of anemia with diabetes mellitus in moderate kidney insufficiency: The Kidney Early Evaluation Program. Kidney International 67:4, pages 1483-1488.
Crossref
Thomas Elung-Jensen, Jens Heisterberg, Jesper Sonne, Svend Strandgaard & Anne-Lise Kamper. (2005) Enalapril dosage in progressive chronic nephropathy: a randomised, controlled trial. European Journal of Clinical Pharmacology 61:2, pages 87-96.
Crossref
H. P. Lefebvre & P. L. Toutain. (2004) Angiotensin-converting enzyme inhibitors in the therapy of renal diseases. Journal of Veterinary Pharmacology and Therapeutics 27:5, pages 265-281.
Crossref
G. Michael Felker, Kirkwood F. AdamsJrJr, Wendy A. Gattis & Christopher M. O'Connor. (2004) Anemia as a risk factor and therapeutic target in heart failure. Journal of the American College of Cardiology 44:5, pages 959-966.
Crossref
Klaus K.A Witte, Ramesh Desilva, Sudipta Chattopadhyay, Justin Ghosh, John G.F Cleland & Andrew L Clark. (2004) Are hematinic deficiencies the cause of anemia in chronic heart failure?. American Heart Journal 147:5, pages 924-930.
Crossref
Demetrios V. Vlahakos, Katerina P. Marathias, Basil Agroyannis & Nicolaos E. Madias. (2003) Posttransplant erythrocytosis. Kidney International 63:4, pages 1187-1194.
Crossref
Sandra Donnelly. 2003. Hypoxia. Hypoxia 73 87 .
Mark J Sarnak, Amin Al-Ahmad, William M Rand, Deeb Salem & Andrew S Levey. (2002) Reply. Journal of the American College of Cardiology 39:10, pages 1704-1705.
Crossref
Angela Yee Moon Wang, Alex Wai Yin Yu, Christopher Wai Kei Lam, Ly Mee Yu, Philip Kam Tao Li, Juliana Goh & Siu Fai Lui. (2002) Effects of losartan or enalapril on hemoglobin, circulating erythropoietin, and insulin-like growth factor-1 in patients with and without posttransplant erythrocytosis. American Journal of Kidney Diseases 39:3, pages 600-608.
Crossref
Allen R. Nissenson & Eric M. Tong. 2002. Improving Prognosis for Kidney Disorders. Improving Prognosis for Kidney Disorders 9 27 .
Sandra M Donnelly & Judith A Miller. (2016) Losartan may modulate erythropoietin production. Journal of the Renin-Angiotensin-Aldosterone System 2:4, pages 255-260.
Crossref
Jan Gossmann, Ralf Burkhardt, Sebastian Harder, Tomas Lenz, Annette Sedlmeyer, Ute Klinkhardt, Helmut Geiger & Ernst-Heinrich Scheuermann. (2001) Angiotensin II infusion increases plasma erythropoietin levels via an angiotensin II type 1 receptor-dependent pathway. Kidney International 60:1, pages 83-86.
Crossref
Sofia Feinstein, Rachel Becker-Cohen, Nurti Algur, David Raveh, Hanna Shalev, Yigal Shvil & Yaacov Frishberg. (2001) Erythropoietin deficiency causes anemia in nephrotic children with normal kidney function. American Journal of Kidney Diseases 37:4, pages 736-742.
Crossref
D Montanaro, M Gropuzzo, P Tulissi, G Boscutti, A Risaliti, U Baccarani & G Mioni. (2001) Angiotensin-converting enzyme inhibitors reduce hemoglobin concentrations, hematocrit, and serum erythropoietin levels in renal transplant recipients without posttransplant erythrocytosis. Transplantation Proceedings 33:1-2, pages 2038-2040.
Crossref
Justin Cole, Dilek Ertoy, Hsinchen Lin, Roy L. Sutliff, Eric Ezan, Tham T. Guyene, Mario Capecchi, Pierre Corvol & Kenneth E. Bernstein. (2000) Lack of angiotensin II–facilitated erythropoiesis causes anemia in angiotensin-converting enzyme–deficient mice. Journal of Clinical Investigation 106:11, pages 1391-1398.
Crossref
Bidisha Chatterjee, Urs E. Nydegger & Paul Mohacsi. (2001) Serum erythropoietin in heart failure patients treated with ACE‐inhibitors or AT 1 antagonists . European Journal of Heart Failure 2:4, pages 393-398.
Crossref
Ali K. Abu-Alfa, Dinna Cruz, Mark A. Perazella, Rex L. Mahnensmith, David Simon & Margaret J. Bia. (2000) Ace inhibitors do not induce recombinant human erythropoietin resistance in hemodialysis patients. American Journal of Kidney Diseases 35:6, pages 1076-1082.
Crossref
Şehsuvar Ertürk, Gökhan Nergizoğlu, Kenan Ateş, Neval Duman, Bülent Erbay, Oktay Karatan & A. Ergün Ertuğ. (1999) The impact of withdrawing ACE inhibitors on erythropoietin responsiveness and left ventricular hypertrophy in haemodialysis patients. Nephrology Dialysis Transplantation 14:8, pages 1912-1916.
Crossref
Iain C. Macdougall. (1999) The role of ACE inhibitors and angiotensin II receptor blockers in the response to epoetin. Nephrology Dialysis Transplantation 14:8, pages 1836-1841.
Crossref
R. Antonelli Incalzi, Antonella Gemma & PierUgo Carbonin. (1998) ACE INHIBITORS: A POSSIBLE CAUSE OF UNEXPLAINED ANEMIA. Journal of the American Geriatrics Society 46:1, pages 117-118.
Crossref
J. Radermacher & Karl M. Koch. 1997. Suki and Massry’s THERAPY OF RENAL DISEASES AND RELATED DISORDERS. Suki and Massry’s THERAPY OF RENAL DISEASES AND RELATED DISORDERS 875 892 .
Mathew J. Lewis & Suzanne K. Swan. (2007) A Potpourri of Drug Idiosyncracies in ESRD. Seminars in Dialysis 10:5, pages 278-281.
Crossref
Luigi F. Morrone, Salvatore Di Paolo, Francesco Logoluso, Antonio Schena, Giovanni Stallone, Francesco Giorgino & F. Paolo Schena. (1997) INTERFERENCE OF ANGIOTENSIN-CONVERTING ENZYME INHIBITORS ON ERYTHROPOIESIS IN KIDNEY TRANSPLANT RECIPIENTS. Transplantation 64:6, pages 913-918.
Crossref
D. Ducloux & J.M. Chalopin. (1997) Losartan decreases hemoglobin in renal transplant recipients. Transplantation Proceedings 29:5, pages 2402-2403.
Crossref
T. Yagisawa, H. Toma, H. Yaguchi, M. Tomaru, Y. Iijima, H. Suzuki & T. Nakada. (1997) Efficacy of Enalapril after ineffective theophylline treatment on erythrocytosis after renal transplantation. International Urology and Nephrology 29:3, pages 363-367.
Crossref
Fernando Valderrábano. (1996) Erythropoietin in chronic renal failure. Kidney International 50:4, pages 1373-1391.
Crossref
Dinna N. Cruz, Mark A. Perazella, Ali K. Abu-Alfa & Rex L. Mahnensmith. (1996) Angiotensin-converting enzyme inhibitor therapy in chronic hemodialysis patients: Any evidence of erythropoietin resistance?. American Journal of Kidney Diseases 28:4, pages 535-540.
Crossref
Jan Gossmann, Petra Thürmann, Thomas Bachmann, Stefan Weller, Hans-Georg Kachel, Wilhelm Schoeppe & Ernst-Heinrich Scheuermann. (1996) Mechanism of angiotensin converting enzyme inhibitor-related anemia in renal transplant recipients. Kidney International 50:3, pages 973-978.
Crossref
A. R. Nissenson. (2020) Hyporesponsiveness to Erythropoietin: Overview, 1996. Peritoneal Dialysis International: Journal of the International Society for Peritoneal Dialysis 16:4, pages 417-420.
Crossref
Jesús Egido. (1996) Vasoactive hormones and renal sclerosis. Kidney International 49:2, pages 578-597.
Crossref
K.C. Wong, K.S. Woo, W.K. Lam, K.T. Li, K.N. Lai, M.G. Nicholls & S.F. Lui. (2018) A Comparison of the Effect of Enalapril and Metoprolol on Renal Function, Potassium Balance, Lipid Profile, Cardiac Function, Exercise Tolerance and Quality of Life in Hypertensive Dialysis Patients. The International Journal of Artificial Organs 18:12, pages 757-762.
Crossref
Mark Perazella, Peter McPhedran, Alan Kliger, Marc Lorber, Elliott Levy & Margaret J. Bia. (1995) Enalapril treatment of posttransplant erythrocytosis: efficacy independent of circulating erythropoietin levels. American Journal of Kidney Diseases 26:3, pages 495-500.
Crossref
Zbigniew Szyguła, Johan Smitz, Johan Roeykens, Kenny De Meirleir & Tom Klausen. (1995) An early effect of acute plasma volume expansion in humans on serum erythropoietin concentration. European Journal of Applied Physiology and Occupational Physiology 72:1-2, pages 106-110.
Crossref
Bruce A. Julian, Robert S. Gaston, Catherine V. Barker, Gerald Krystal, Arnold G. Diethelm & John J. Curtis. (1994) Erythropoiesis after withdrawal of enalapril in post-transplant erythrocytosis. Kidney International 46:5, pages 1397-1403.
Crossref
L. D. Elving, J. F. M. Wetzels, H. J. J. van Lier, E. de Nobel & J. H. M. Berden. (1994) Captopril and atenolol are equally effective in retarding progression of diabetic nephropathy. Diabetologia 37:6, pages 604-609.
Crossref
R. Martino, A. Oliver, J. M. Ballarín & A. F. Remacha. (1994) Postrenal transplant erythrocytosis: Further evidence implicating erythropoietin production by the native kidneys. Annals of Hematology 68:4, pages 201-203.
Crossref
Antonio Salvetti, Roberto Giovannetti, Pieranna Arrighi, Fabrizio Arzilli & Roberto Palla. (1993) What Effect Does Blood Pressure Control Have on the Progression Toward Renal Failure?. American Journal of Kidney Diseases 21:6, pages S10-S15.
Crossref
J. D. JENSEN, H. EISKJÆR, J. P. BAGGER & E. B. PEDERSEN. (2009) Elevated level of erythropoietin in congestive heart failure Relationship to renal perfusion and plasma renin. Journal of Internal Medicine 233:2, pages 125-130.
Crossref
MC Pratt, NJ Lewis‐Barned, RJ Walker, RR Bailey, BI Shand & J. Livesey. (2012) Effect of angiotensin converting enzyme inhibitors on erythropoietin concentrations in healthy volunteers.. British Journal of Clinical Pharmacology 34:4, pages 363-365.
Crossref
Jeffrey W. Nielsen & Vincent J. Canzanello. (2007) Captopril and Anemia. Seminars in Dialysis 5:2, pages 159-160.
Crossref
A. D. Graafland, C. J. Doorenbos & J. C. L. M. Saase. (1992) Enalapril-induced anemia in two kidney transplant recipients. Transplant International 5:1, pages 51-53.
Crossref
S. Bjorck, H. Mulec, S. A. Johnsen, G. Norden & M. Aurell. (1992) Renal protective effect of enalapril in diabetic nephropathy.. BMJ 304:6823, pages 339-343.
Crossref

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