1,409
Views
96
CrossRef citations to date
0
Altmetric
Original Article

Placebo-controlled, randomised clinical trial: high-dose resveratrol treatment for non-alcoholic fatty liver disease

, , , , , , , , , & show all
Pages 456-464 | Received 28 Aug 2015, Accepted 07 Oct 2015, Published online: 19 Jan 2016

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (7)

Ramya Venkat, Elika Verma, Uzini Devi Daimary, Aviral Kumar, Sosmitha Girisa, Uma Dutta, Kwang Seok Ahn & Ajaikumar B. Kunnumakkara. (2023) The Journey of Resveratrol from Vineyards to Clinics. Cancer Investigation 41:2, pages 183-220.
Read now
Tea Lund Laursen, Anders Mellemkjær, Holger Jon Møller, Henning Grønbæk & Konstantin Kazankov. (2022) Spotlight on liver macrophages for halting injury and progression in nonalcoholic fatty liver disease. Expert Opinion on Therapeutic Targets 26:8, pages 697-705.
Read now
Reza Tabrizi, Omid Reza Tamtaji, Kamran B. Lankarani, Maryam Akbari, Ehsan Dadgostar, Mohammad Hossein Dabbaghmanesh, Fariba Kolahdooz, Amir Shamshirian, Mansooreh Momen-Heravi & Zatollah Asemi. (2020) The effects of resveratrol intake on weight loss: a systematic review and meta-analysis of randomized controlled trials. Critical Reviews in Food Science and Nutrition 60:3, pages 375-390.
Read now
Federica Fogacci, Giuliano Tocci, Vivianne Presta, Andrea Fratter, Claudio Borghi & Arrigo F. G. Cicero. (2019) Effect of resveratrol on blood pressure: A systematic review and meta-analysis of randomized, controlled, clinical trials. Critical Reviews in Food Science and Nutrition 59:10, pages 1605-1618.
Read now
Xiao-Fei Guo, Jiao-Mei Li, Jun Tang & Duo Li. (2018) Effects of resveratrol supplementation on risk factors of non-communicable diseases: A meta-analysis of randomized controlled trials. Critical Reviews in Food Science and Nutrition 58:17, pages 3016-3029.
Read now
Somayyeh Asghari, Mohammad Asghari-Jafarabadi, Mohammad-Hossein Somi, Seyed-Mostafa Ghavami & Maryam Rafraf. (2018) Comparison of Calorie-Restricted Diet and Resveratrol Supplementation on Anthropometric Indices, Metabolic Parameters, and Serum Sirtuin-1 Levels in Patients With Nonalcoholic Fatty Liver Disease: A Randomized Controlled Clinical Trial. Journal of the American College of Nutrition 37:3, pages 223-233.
Read now
Gesthimani Mintziori & Stergios A. Polyzos. (2016) Emerging and future therapies for nonalcoholic steatohepatitis in adults. Expert Opinion on Pharmacotherapy 17:14, pages 1937-1946.
Read now

Articles from other publishers (89)

Pin Gong, Hui Long, Yuxi Guo, Zhineng Wang, Wenbo Yao, Jing Wang, Wenjuan Yang, Nan Li, Jianwu Xie & Fuxin Chen. (2024) Chinese herbal medicines: The modulator of nonalcoholic fatty liver disease targeting oxidative stress. Journal of Ethnopharmacology 318, pages 116927.
Crossref
Decheng Meng, Fengxia Zhang, Wenfei Yu, Xin Zhang, Guoliang Yin, Pengpeng Liang, Yanan Feng, Suwen Chen & Hongshuai Liu. (2023) Biological Role and Related Natural Products of SIRT1 in Nonalcoholic Fatty Liver. Diabetes, Metabolic Syndrome and Obesity Volume 16, pages 4043-4064.
Crossref
Jeong-Su Park, Nodir Rustamov & Yoon-Seok Roh. (2023) The Roles of NFR2-Regulated Oxidative Stress and Mitochondrial Quality Control in Chronic Liver Diseases. Antioxidants 12:11, pages 1928.
Crossref
Roland Gál, Róbert Halmosi, Ferenc GallyasJr.Jr., Michael Tschida, Pornthira Mutirangura, Kálmán Tóth, Tamás Alexy & László Czopf. (2023) Resveratrol and beyond: The Effect of Natural Polyphenols on the Cardiovascular System: A Narrative Review. Biomedicines 11:11, pages 2888.
Crossref
Qichao Hu, Wenwen Zhang, Feng Wei, Meilan Huang, Mengyao Shu, Dan Song, Jianxia Wen, Jundong Wang, Qing Nian, Xiao Ma, Jinhao Zeng & Yanling Zhao. (2023) Human diet‐derived polyphenolic compounds and hepatic diseases: From therapeutic mechanisms to clinical utilization. Phytotherapy Research.
Crossref
Xuan He, Yubing Li, Xinyu Deng, Xiaolin Xiao & Jinhao Zeng. (2023) Integrative evidence construction for resveratrol treatment of nonalcoholic fatty liver disease: preclinical and clinical meta-analyses. Frontiers in Pharmacology 14.
Crossref
Jaime Zapata, Mauricio Castro-Sepulveda, Sandra Soto-Alarcon, Daniela Alvarez, Andres Bustamante, Guiselle Villarroel, Arturo Gallardo, Diego Fernando Garcia-Diaz, Rodrigo Valenzuela & Francisca Echeverria. (2023) Targeting Mitochondria for the Prevention and Treatment of Nonalcoholic Fatty Liver Disease: Polyphenols as a Non-pharmacological Approach. Current Medicinal Chemistry 30:26, pages 2977-2995.
Crossref
Gustavo Henrique Ferreira Gonçalinho, Karen Lika Kuwabara, Nathalia Ferreira de Oliveira Faria, Marisa Fernandes da Silva Goes, Alessandra Roggerio, Solange Desirée Avakian, Célia Maria Cassaro Strunz & Antonio de Padua Mansur. (2023) Sirtuin 1 and Vascular Function in Healthy Women and Men: A Randomized Clinical Trial Comparing the Effects of Energy Restriction and Resveratrol. Nutrients 15:13, pages 2949.
Crossref
Arefe Nemati, Zeinab Nikniaz & Ali Mota. (2023) Effects of Resveratrol Supplementation on Nonalcoholic Fatty Liver Disease Management. Topics in Clinical Nutrition 38:2, pages 144-160.
Crossref
Marcin Siwek, Adrian Andrzej Chrobak, Aleksandra Gorostowicz, Patrycja Król & Dominika Dudek. (2023) Lurasidone Augmentation of Clozapine in Schizophrenia—Retrospective Chart Review. Brain Sciences 13:3, pages 445.
Crossref
Sepideh Soltani, Elham Sharifi‐Zahabi, Zohreh Sadat Sangsefidi, Azam Ahmadi Vasmehjani, Fatemeh Meshkini, Zachary Stephen Clayton & Shima Abdollahi. (2023) The effect of resveratrol supplementation on biomarkers of liver health: A systematic review and meta‐analysis of randomized controlled trials . Phytotherapy Research 37:3, pages 1153-1166.
Crossref
Anns Mahboob, Degiri Kalana Lasanga Senevirathne, Pradipta Paul, Faisal Nabi, Rizwan Hasan Khan & Ali Chaari. (2023) An investigation into the potential action of polyphenols against human Islet Amyloid Polypeptide aggregation in type 2 diabetes. International Journal of Biological Macromolecules 225, pages 318-350.
Crossref
Putri Anggreini, Hadi Kuncoro, Sri Sumiwi & Jutti Levita. (2022) Role of the AMPK/SIRT1 pathway in non‑alcoholic fatty liver disease (Review). Molecular Medicine Reports 27:2.
Crossref
Kailin Yang, Junpeng Chen, Tianqing Zhang, Xiao Yuan, Anqi Ge, Shanshan Wang, Hao Xu, Liuting Zeng & Jinwen Ge. (2022) Efficacy and safety of dietary polyphenol supplementation in the treatment of non-alcoholic fatty liver disease: A systematic review and meta-analysis. Frontiers in Immunology 13.
Crossref
Xingtao Zhao, Xinyan Xue, Cheng Wang, Jing Wang, Cheng Peng & Yunxia Li. (2022) Emerging roles of Sirtuins in alleviating alcoholic liver Disease: A comprehensive review. International Immunopharmacology 108, pages 108712.
Crossref
Ashley Hillsley, Vanessa Chin, Amy Li & Craig S. McLachlan. (2022) Resveratrol for Weight Loss in Obesity: An Assessment of Randomized Control Trial Designs in ClinicalTrials.gov. Nutrients 14:7, pages 1424.
Crossref
Roohi Mohi-ud-din, Reyaz Hassan Mir, Nazia Banday, Saba Sabreen, Abdul Jalil Shah, Rafia Jan, Taha Umair Wani, Saeema Farooq & Zulfiqar Ali Bhat. 2022. 99 137 .
Mina Karimi, Behnaz Abiri, Paul C. Guest & Mohammadreza Vafa. 2022. Physical Exercise and Natural and Synthetic Products in Health and Disease. Physical Exercise and Natural and Synthetic Products in Health and Disease 19 35 .
Qiangqiang Li, Guangpu Yang, Hongtao Xu, Shaowen Tang & Wayne Yuk-wai Lee. (2021) Effects of resveratrol supplementation on bone quality: a systematic review and meta-analysis of randomized controlled trials. BMC Complementary Medicine and Therapies 21:1.
Crossref
Chengyuan Liang, Juan Li, Bin Tian, Lei Tian, Yuzhi Liu, Jingyi Li, Liang Xin, Jun Wang, Chao Fu, Zhenfeng Shi, Juan Xia, Yiting Liang & Kun Wang. (2021) Foresight regarding drug candidates acting on the succinate–GPR91 signalling pathway for non-alcoholic steatohepatitis (NASH) treatment. Biomedicine & Pharmacotherapy 144, pages 112298.
Crossref
Rou Tang, Rui Li, He Li, Xiao-Lei Ma, Peng Du, Xiao-You Yu, Ling Ren, Lu-Lu Wang & Wen-Sheng Zheng. (2021) Design of Hepatic Targeted Drug Delivery Systems for Natural Products: Insights into Nomenclature Revision of Nonalcoholic Fatty Liver Disease. ACS Nano 15:11, pages 17016-17046.
Crossref
Julia T. Stadler & Gunther Marsche. (2021) Dietary Strategies to Improve Cardiovascular Health: Focus on Increasing High-Density Lipoprotein Functionality. Frontiers in Nutrition 8.
Crossref
Victoria Potoupni, Maria Georgiadou, Eftychia Chatzigriva, Georgia Polychronidou, Erietta Markou, Christos Zapantis Gakis, Ioanna Filimidou, Myriam Karagianni, Dimitrios Anastasilakis, Kleo Evripidou, Argyro Ftergioti, Marianthi Togkaridou, Nikolaos Tsaftaridis, Apostolos Apostolopoulos & Stergios A Polyzos. (2021) Circulating tumor necrosis factor‐α levels in non‐alcoholic fatty liver disease: A systematic review and a meta‐analysis. Journal of Gastroenterology and Hepatology 36:11, pages 3002-3014.
Crossref
Sheida Zeraattalab-Motlagh, Ahmad Jayedi & Sakineh Shab-Bidar. (2021) The effects of resveratrol supplementation in patients with type 2 diabetes, metabolic syndrome, and nonalcoholic fatty liver disease: an umbrella review of meta-analyses of randomized controlled trials. The American Journal of Clinical Nutrition 114:5, pages 1675-1685.
Crossref
Alyson M. Curry, Dawanna S. White, Dickson Donu & Yana Cen. (2021) Human Sirtuin Regulators: The “Success” Stories. Frontiers in Physiology 12.
Crossref
Zuqing Su, Yanru Guo, Xiufang Huang, Bing Feng, Lipeng Tang, Guangjuan Zheng & Ying Zhu. (2021) Phytochemicals: Targeting Mitophagy to Treat Metabolic Disorders. Frontiers in Cell and Developmental Biology 9.
Crossref
Oluyemi Komolafe, Elena Buzzetti, Audrey Linden, Lawrence MJ Best, Angela M Madden, Danielle Roberts, Thomas JG Chase, Dominic Fritche, Suzanne C Freeman, Nicola J Cooper, Alex J Sutton, Elisabeth Jane Milne, Kathy Wright, Chavdar S Pavlov, Brian R Davidson, Emmanuel Tsochatzis & Kurinchi Selvan Gurusamy. (2021) Nutritional supplementation for nonalcohol-related fatty liver disease: a network meta-analysis. Cochrane Database of Systematic Reviews 2021:7.
Crossref
Shiyao Zhang, Mengyi Xu, Wenxiang Zhang, Chang Liu & Siyu Chen. (2021) Natural Polyphenols in Metabolic Syndrome: Protective Mechanisms and Clinical Applications. International Journal of Molecular Sciences 22:11, pages 6110.
Crossref
Megha Jhanji, Chintada Nageswara Rao & Mathew Sajish. (2020) Towards resolving the enigma of the dichotomy of resveratrol: cis- and trans-resveratrol have opposite effects on TyrRS-regulated PARP1 activation. GeroScience 43:3, pages 1171-1200.
Crossref
Nikola Gligorijević, Dragana Stanić-Vučinić, Mirjana Radomirović, Marija Stojadinović, Urmila Khulal, Olgica Nedić & Tanja Ćirković Veličković. (2021) Role of Resveratrol in Prevention and Control of Cardiovascular Disorders and Cardiovascular Complications Related to COVID-19 Disease: Mode of Action and Approaches Explored to Increase Its Bioavailability. Molecules 26:10, pages 2834.
Crossref
Howard H. Bailey, Jeremy J. Johnson, Taja Lozar, Cameron O. Scarlett, Barbara W. Wollmer, KyungMann Kim, Thomas Havinghurst & Nihal Ahmad. (2020) A randomized, double-blind, dose-ranging, pilot trial of piperine with resveratrol on the effects on serum levels of resveratrol. European Journal of Cancer Prevention 30:3, pages 285-290.
Crossref
Mina Darand, Amirhosein Farrokhzad, Abed Ghavami, Amir Hadi, Elham Karimi, Abdulmnannan Fadel & Gholamreza Askari. (2020) Effects of resveratrol supplementation on liver enzymes: A systematic review and meta‐analysis of randomised controlled trials. International Journal of Clinical Practice 75:3.
Crossref
Shumin Wei & Xiaoying Yu. (2021) Efficacy of resveratrol supplementation on liver enzymes in patients with non-alcoholic fatty liver disease: A systematic review and meta-analysis. Complementary Therapies in Medicine 57, pages 102635.
Crossref
Naemat Sandhu & Jennifer Au. (2021) Herbal Medicines for the Treatment of Nonalcoholic Steatohepatitis. Current Hepatology Reports 20:1, pages 1-11.
Crossref
Sahar Rafiee, Hamed Mohammadi, Abed Ghavami, Erfan Sadeghi, Zahra Safari & Gholamreza Askari. (2021) Efficacy of resveratrol supplementation in patients with nonalcoholic fatty liver disease: A systematic review and meta-analysis of clinical trials. Complementary Therapies in Clinical Practice 42, pages 101281.
Crossref
Samuel R. Weaver, Catarina Rendeiro, Helen M. McGettrick, Andrew Philp & Samuel J. E. Lucas. (2020) Fine wine or sour grapes? A systematic review and meta-analysis of the impact of red wine polyphenols on vascular health. European Journal of Nutrition 60:1, pages 1-28.
Crossref
Jingwen Zhou, Yidi Chen, Jun Yu, Tianci Li, Ziyu Lu, Yan Chen, Xiaolong Zhang & Fang Ye. (2021) The efficacy of novel metabolic targeted agents and natural plant drugs for nonalcoholic fatty liver disease treatment. Medicine 100:12, pages e24884.
Crossref
Antoni Sureda, Xavier Capó & Silvia Tejada. 2021. Influence of Nutrients, Bioactive Compounds, and Plant Extracts in Liver Diseases. Influence of Nutrients, Bioactive Compounds, and Plant Extracts in Liver Diseases 83 103 .
Surinder Kumar, William Giblin & David B. Lombard. 2021. Handbook of the Biology of Aging. Handbook of the Biology of Aging 77 149 .
Luis E. Simental-Mendía, Claudia I. Gamboa-Gómez, Fernando Guerrero-Romero, Mario Simental-Mendía, Adriana Sánchez-García & Mariana Rodríguez-Ramírez. 2021. Pharmacological Properties of Plant-Derived Natural Products and Implications for Human Health. Pharmacological Properties of Plant-Derived Natural Products and Implications for Human Health 257 272 .
David E. Stec & Terry D. HindsJr.Jr.. (2020) Natural Product Heme Oxygenase Inducers as Treatment for Nonalcoholic Fatty Liver Disease. International Journal of Molecular Sciences 21:24, pages 9493.
Crossref
Maryam Akbari, Omid Reza Tamtaji, Kamran B. Lankarani, Reza Tabrizi, Ehsan Dadgostar, Neda Haghighat, Fariba Kolahdooz, Amir Ghaderi, Mohammad Ali Mansournia & Zatollah Asemi. (2020) The effects of resveratrol on lipid profiles and liver enzymes in patients with metabolic syndrome and related disorders: a systematic review and meta-analysis of randomized controlled trials. Lipids in Health and Disease 19:1.
Crossref
Henrik H. Hansen, Helene M. Ægidius, Denise Oró, Simon S. Evers, Sara Heebøll, Peter Lykke Eriksen, Karen Louise Thomsen, Anja Bengtsson, Sanne S. Veidal, Michel Feigh, Malte P. Suppli, Filip K. Knop, Henning Grønbæk, Diego Miranda, James L. Trevaskis, Niels Vrang, Jacob Jelsing & Kristoffer T. G. Rigbolt. (2020) Human translatability of the GAN diet-induced obese mouse model of non-alcoholic steatohepatitis. BMC Gastroenterology 20:1.
Crossref
I. Milton-Laskibar, L. Aguirre, S. Gómez-Zorita, A. P. Rolo & M. P. Portillo. (2020) The influence of dietary conditions in the effects of resveratrol on hepatic steatosis. Food & Function 11:11, pages 9432-9444.
Crossref
Karolina Jakubczyk, Karolina Skonieczna-Żydecka, Justyna Kałduńska, Ewa Stachowska, Izabela Gutowska & Katarzyna Janda. (2020) Effects of Resveratrol Supplementation in Patients with Non-Alcoholic Fatty Liver Disease—A Meta-Analysis. Nutrients 12:8, pages 2435.
Crossref
Brittanie Kilchoer, Anina Vils, Beatrice Minder, Taulant Muka, Marija Glisic & Lia Bally. (2020) Efficacy of Dietary Supplements to Reduce Liver Fat. Nutrients 12:8, pages 2302.
Crossref
Pan Wang, Jing Wang, Daotong Li, Weixin Ke, Fang Chen & Xiaosong Hu. (2020) Targeting the gut microbiota with resveratrol: a demonstration of novel evidence for the management of hepatic steatosis. The Journal of Nutritional Biochemistry 81, pages 108363.
Crossref
L. Farzin, S. Asghari, M. Rafraf, M. Asghari-Jafarabadi & M. Shirmohammadi. (2020) No beneficial effects of resveratrol supplementation on atherogenic risk factors in patients with nonalcoholic fatty liver disease. International Journal for Vitamin and Nutrition Research 90:3-4, pages 279-289.
Crossref
Maria Mirabelli, Eusebio Chiefari, Biagio Arcidiacono, Domenica Maria Corigliano, Francesco Saverio Brunetti, Valentina Maggisano, Diego Russo, Daniela Patrizia Foti & Antonio Brunetti. (2020) Mediterranean Diet Nutrients to Turn the Tide against Insulin Resistance and Related Diseases. Nutrients 12:4, pages 1066.
Crossref
Chih-Chun Chang, Chieh-Yu Chang, Pei-Chun Lin, Jiung-Pang Huang, Kuan-Hsing Chen, Tzung-Hai Yen & Li-Man Hung. (2020) Administration of low-dose resveratrol attenuated hepatic inflammation and lipid accumulation in high cholesterol-fructose diet-induced rat model of nonalcoholic fatty liver disease. Chinese Journal of Physiology 63:4, pages 149.
Crossref
Shuo Zhang, Yan Ma & Juan Feng. (2020) Neuroprotective mechanisms of ε-viniferin in a rotenone-induced cell model of Parkinson's disease: significance of SIRT3-mediated FOXO3 deacetylation. Neural Regeneration Research 15:11, pages 2143.
Crossref
Marzieh Asis, Niloufar Hemmati, Sajjad Moradi, Kalyan C. Nagulapalli Venkata, Elham Mohammadi, Mohammad Hosein Farzaei & Anupam Bishayee. (2019) Effects of resveratrol supplementation on bone biomarkers: a systematic review and meta‐analysis. Annals of the New York Academy of Sciences 1457:1, pages 92-103.
Crossref
Peter Lykke Eriksen, Hendrik Vilstrup, Kristoffer Rigbolt, Malte P. Suppli, Michael Sørensen, Sara Heebøll, Sanne S. Veidal, Fillip K. Knop & Karen Louise Thomsen. (2019) Non‐alcoholic fatty liver disease alters expression of genes governing hepatic nitrogen conversion. Liver International 39:11, pages 2094-2101.
Crossref
Akhand Pratap Singh, Rachna Singh, Sumit Singh Verma, Vipin Rai, Catherine H. Kaschula, Pralay Maiti & Subash Chandra Gupta. (2019) Health benefits of resveratrol: Evidence from clinical studies. Medicinal Research Reviews 39:5, pages 1851-1891.
Crossref
Elias Immanuel Ordell Sundelin, Lars Christian Gormsen, Sara Heebøll, Mikkel Holm Vendelbo, Steen Jakobsen, Ole Lajord Munk, Søren Feddersen, Kim Brøsen, Stephen Jacques Hamilton‐Dutoit, Steen Bønløkke Pedersen, Henning Grønbæk & Niels Jessen. (2019) Hepatic exposure of metformin in patients with non‐alcoholic fatty liver disease. British Journal of Clinical Pharmacology 85:8, pages 1761-1770.
Crossref
Maryam Akbari, Omid Reza Tamtaji, Kamran B. Lankarani, Reza Tabrizi, Ehsan Dadgostar, Fariba Kolahdooz, Mehri Jamilian, Hamed Mirzaei & Zatollah Asemi. (2019) The Effects of Resveratrol Supplementation on Endothelial Function and Blood Pressures Among Patients with Metabolic Syndrome and Related Disorders: A Systematic Review and Meta-Analysis of Randomized Controlled Trials. High Blood Pressure & Cardiovascular Prevention 26:4, pages 305-319.
Crossref
Liyuan Zhou, Xinhua Xiao, Qian Zhang, Jia Zheng & Mingqun Deng. (2019) Deciphering the Anti-obesity Benefits of Resveratrol: The “Gut Microbiota-Adipose Tissue” Axis. Frontiers in Endocrinology 10.
Crossref
Ana María Ruiz-León, María Lapuente, Ramon Estruch & Rosa Casas. (2019) Clinical Advances in Immunonutrition and Atherosclerosis: A Review. Frontiers in Immunology 10.
Crossref
Malte P. Suppli, Kristoffer T. G. Rigbolt, Sanne S. Veidal, Sara Heebøll, Peter Lykke Eriksen, Mia Demant, Jonatan I. Bagger, Jens Christian Nielsen, Denise Oró, Sebastian W. Thrane, Asger Lund, Charlotte Strandberg, Merete J. Kønig, Tina Vilsbøll, Niels Vrang, Karen L. Thomsen, Henning Grønbæk, Jacob Jelsing, Henrik H. Hansen & Filip K. Knop. (2019) Hepatic transcriptome signatures in patients with varying degrees of nonalcoholic fatty liver disease compared with healthy normal-weight individuals. American Journal of Physiology-Gastrointestinal and Liver Physiology 316:4, pages G462-G472.
Crossref
S. M. Mousavi, A. Milajerdi, A. Sheikhi, H. Kord‐Varkaneh, C. Feinle‐Bisset, B. Larijani & A. Esmaillzadeh. (2018) Resveratrol supplementation significantly influences obesity measures: a systematic review and dose–response meta‐analysis of randomized controlled trials. Obesity Reviews 20:3, pages 487-498.
Crossref
Mohsen Mazidi, Niki Katsiki & Maciej Banach. (2019) A higher flavonoid intake is associated with less likelihood of nonalcoholic fatty liver disease: results from a multiethnic study. The Journal of Nutritional Biochemistry 65, pages 66-71.
Crossref
Ma Ai Thanda Han, Osama Altayar, Shadi Hamdeh, Varun Takyar, Yaron Rotman, Ohad Etzion, Eric Lefebvre, Rifaat Safadi, Vlad Ratziu, Larry J. Prokop, Mohammad Hassan Murad & Mazen Noureddin. (2019) Rates of and Factors Associated With Placebo Response in Trials of Pharmacotherapies for Nonalcoholic Steatohepatitis: Systematic Review and Meta-analysis. Clinical Gastroenterology and Hepatology 17:4, pages 616-629.e26.
Crossref
Garrison Dyck, Pema Raj, Shelley Zieroth, Jason Dyck & Justin Ezekowitz. (2019) The Effects of Resveratrol in Patients with Cardiovascular Disease and Heart Failure: A Narrative Review. International Journal of Molecular Sciences 20:4, pages 904.
Crossref
Alice Chaplin, Christian Carpéné & Josep Mercader. (2018) Resveratrol, Metabolic Syndrome, and Gut Microbiota. Nutrients 10:11, pages 1651.
Crossref
Shuqian Wan, Long Zhang, Yunyun Quan & Kun Wei. (2018) Resveratrol-loaded PLGA nanoparticles: enhanced stability, solubility and bioactivity of resveratrol for non-alcoholic fatty liver disease therapy. Royal Society Open Science 5:11, pages 181457.
Crossref
Kannan Sridharan, Gowri Sivaramakrishnan, Reginald Paul Sequeira & Abdelaziz Elamin. (2018) Pharmacological interventions for non-alcoholic fatty liver disease: a systematic review and network meta-analysis. Postgraduate Medical Journal 94:1116, pages 556-565.
Crossref
Marianne K. Poulsen, Birgitte Nellemann, Bo Martin Bibby, Hans Stødkilde‐Jørgensen, Steen B. Pedersen, Henning Grønbæk & Søren Nielsen. (2018) No effect of resveratrol on VLDL‐TG kinetics and insulin sensitivity in obese men with nonalcoholic fatty liver disease. Diabetes, Obesity and Metabolism 20:10, pages 2504-2509.
Crossref
Brandon Perumpail, Andrew Li, Umair Iqbal, Sandy Sallam, Neha Shah, Waiyee Kwong, George Cholankeril, Donghee Kim & Aijaz Ahmed. (2018) Potential Therapeutic Benefits of Herbs and Supplements in Patients with NAFLD. Diseases 6:3, pages 80.
Crossref
Hani M. Khojah, Sameh Ahmed, Mahran S. Abdel-Rahman & Eman H. Elhakeim. (2018) Resveratrol as an effective adjuvant therapy in the management of rheumatoid arthritis: a clinical study. Clinical Rheumatology 37:8, pages 2035-2042.
Crossref
Gemma Navarro, Eva Martínez -Pinilla, Raquel Ortiz, Véronique Noé, Carlos J. Ciudad & Rafael Franco. (2018) Resveratrol and Related Stilbenoids, Nutraceutical/Dietary Complements with Health-Promoting Actions: Industrial Production, Safety, and the Search for Mode of Action. Comprehensive Reviews in Food Science and Food Safety 17:4, pages 808-826.
Crossref
Somayyeh Asghari, Maryam Rafraf, Laleh Farzin, Mohammad Asghari-Jafarabadi, Seyed-Mostafa Ghavami & Mohammad-Hossein Somi. (2018) Effects of Pharmacologic Dose of Resveratrol Supplementation on Oxidative/Antioxidative Status Biomarkers in Nonalcoholic Fatty Liver Disease Patients: A Randomized, Double-Blind, Placebo-Controlled Trial. Advanced Pharmaceutical Bulletin 8:2, pages 307-317.
Crossref
Mohammad Bagherniya, Valerio Nobili, Christopher N. Blesso & Amirhossein Sahebkar. (2018) Medicinal plants and bioactive natural compounds in the treatment of non-alcoholic fatty liver disease: A clinical review. Pharmacological Research 130, pages 213-240.
Crossref
Claus Uhrenholt Christensen, Emilie Glavind, Karen Louise Thomsen, Yong Ook Kim, Sara Heebøll, Detlef Schuppan, Stephen Hamilton-Dutoit, Christian Würtz Heegaard & Henning Grønbæk. (2018) Niemann-Pick type C2 protein supplementation in experimental non-alcoholic fatty liver disease. PLOS ONE 13:3, pages e0192728.
Crossref
Fahimeh Haghighatdoost & Mitra Hariri. (2018) Effect of resveratrol on lipid profile: An updated systematic review and meta-analysis on randomized clinical trials. Pharmacological Research 129, pages 141-150.
Crossref
Konrad de Vries, Morné Strydom & Vanessa Steenkamp. (2018) Bioavailability of resveratrol: Possibilities for enhancement. Journal of Herbal Medicine 11, pages 71-77.
Crossref
William M. Schultz, Elliot N. Mahlof, Devinder S. Dhindsa, Tina Varghese, Robert E. Heinl, Hannah C. Cai, Pratik B. Sandesara, Danny J. Eapen & Laurence S. Sperling. (2017) Cardiovascular disease risk reduction in diabetes through conventional and natural approaches. Cardiovascular Endocrinology 6:4, pages 128-135.
Crossref
Giuseppe Della Pepa, Claudia Vetrani, Gianluca Lombardi, Lutgarda Bozzetto, Giovanni Annuzzi & Angela Rivellese. (2017) Isocaloric Dietary Changes and Non-Alcoholic Fatty Liver Disease in High Cardiometabolic Risk Individuals. Nutrients 9:10, pages 1065.
Crossref
Adi Y. Berman, Rachel A. Motechin, Maia Y. Wiesenfeld & Marina K. Holz. (2017) The therapeutic potential of resveratrol: a review of clinical trials. npj Precision Oncology 1:1.
Crossref
Cesidio Giuliani, Manuela Iezzi, Laura Ciolli, Alba Hysi, Ines Bucci, Serena Di Santo, Cosmo Rossi, Mirco Zucchelli & Giorgio Napolitano. (2017) Resveratrol has anti-thyroid effects both in vitro and in vivo. Food and Chemical Toxicology 107, pages 237-247.
Crossref
Sabine Weiskirchen & Ralf Weiskirchen. (2017) Resveratrol: Is It Really Good for Liver Health?. Hepatitis Monthly 17:8.
Crossref
Iñaki Milton-Laskibar, Leixuri Aguirre, Alfredo Fernández-Quintela, Anabela Rolo, João Soeiro Teodoro, Carlos Palmeira & María Portillo. (2017) Lack of Additive Effects of Resveratrol and Energy Restriction in the Treatment of Hepatic Steatosis in Rats. Nutrients 9:7, pages 737.
Crossref
S Heebøll, M K Poulsen, M J Ornstrup, T N Kjær, S B Pedersen, S Nielsen, H Grønbæk & A Handberg. (2016) Circulating sCD36 levels in patients with non-alcoholic fatty liver disease and controls. International Journal of Obesity 41:2, pages 262-267.
Crossref
Tomasz Charytoniuk, Krzysztof Drygalski, Karolina Konstantynowicz-Nowicka, Klaudia Berk & Adrian Chabowski. (2017) Alternative treatment methods attenuate the development of NAFLD: A review of resveratrol molecular mechanisms and clinical trials. Nutrition 34, pages 108-117.
Crossref
Guoyong Liu, Qiang Wang, Yan Shi, Xiaofei Peng, Hong Liu, Youming Peng & Liyu He. (2017) Resveratrol Attenuates Adriamycin-Induced Focal Segmental Glomerulosclerosis through C3aR/C5aR- Sphingosine Kinase 1 Pathway. Pharmacology 100:5-6, pages 253-260.
Crossref
Haohai Huang, Guangzhao Chen, Dan Liao, Yongkun Zhu, Rong Pu & Xiaoyan Xue. (2016) The effects of resveratrol intervention on risk markers of cardiovascular health in overweight and obese subjects: a pooled analysis of randomized controlled trials. Obesity Reviews 17:12, pages 1329-1340.
Crossref
Yueli Tian, Jingting Ma, Wudong Wang, Lingjuan Zhang, Jia Xu, Kai Wang & Dongfu Li. (2016) Resveratrol supplement inhibited the NF-κB inflammation pathway through activating AMPKα-SIRT1 pathway in mice with fatty liver. Molecular and Cellular Biochemistry 422:1-2, pages 75-84.
Crossref
Natalie J. Torok. (2016) Dysregulation of redox pathways in liver fibrosis. American Journal of Physiology-Gastrointestinal and Liver Physiology 311:4, pages G667-G674.
Crossref
Vincent Wai-Sun Wong, Shiv Chitturi, Grace Lai-Hung Wong, Jun Yu, Henry Lik-Yuen Chan & Geoffrey C Farrell. (2016) Pathogenesis and novel treatment options for non-alcoholic steatohepatitis. The Lancet Gastroenterology & Hepatology 1:1, pages 56-67.
Crossref
Chongyang Zhang, Weigang Yuan, Jianguo Fang, Wenqing Wang, Pei He, Jiahui Lei & Chunxu Wang. (2016) Efficacy of Resveratrol Supplementation against Non-Alcoholic Fatty Liver Disease: A Meta-Analysis of Placebo-Controlled Clinical Trials. PLOS ONE 11:8, pages e0161792.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.