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Scandinavian Journal of Gastroenterology Volume 21, 1986 - Issue 6
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Original Article

Steady-State Kinetics of 5-Aminosalicylic Acid and Sulfapyridine during Sulfasalazine Prophylaxis in Ulcerative Colitis

S. Bondesen Dept. of Medicine, Community Hospital, Elsinore; Dept. of Medical Gastroenterology C, Herlev, University of Copenhagen, Herlev; Dept. of Pediatrics, Aalborg Hospital, Aalborg; Dept. of Pediatrics, Viborg Hospital, Viborg; Dept. of Pediatrics, Gentofte Hospital, University of Copenhagen, Hellerup; Dept. of Organic Chemistry, Royal Danish School of Pharmacy, Copenhagen, Denmark; Dept. of Medicine P, Division of Gastroenterology, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark; Dept. of Clinical Pharmacology, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark
,
O. H. Nielsen Dept. of Medicine, Community Hospital, Elsinore; Dept. of Medical Gastroenterology C, Herlev, University of Copenhagen, Herlev; Dept. of Pediatrics, Aalborg Hospital, Aalborg; Dept. of Pediatrics, Viborg Hospital, Viborg; Dept. of Pediatrics, Gentofte Hospital, University of Copenhagen, Hellerup; Dept. of Organic Chemistry, Royal Danish School of Pharmacy, Copenhagen, Denmark; Dept. of Medicine P, Division of Gastroenterology, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark; Dept. of Clinical Pharmacology, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark
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J. B. Schou Dept. of Medicine, Community Hospital, Elsinore; Dept. of Medical Gastroenterology C, Herlev, University of Copenhagen, Herlev; Dept. of Pediatrics, Aalborg Hospital, Aalborg; Dept. of Pediatrics, Viborg Hospital, Viborg; Dept. of Pediatrics, Gentofte Hospital, University of Copenhagen, Hellerup; Dept. of Organic Chemistry, Royal Danish School of Pharmacy, Copenhagen, Denmark; Dept. of Medicine P, Division of Gastroenterology, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark; Dept. of Clinical Pharmacology, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark
,
P. H. Jensen Dept. of Medicine, Community Hospital, Elsinore; Dept. of Medical Gastroenterology C, Herlev, University of Copenhagen, Herlev; Dept. of Pediatrics, Aalborg Hospital, Aalborg; Dept. of Pediatrics, Viborg Hospital, Viborg; Dept. of Pediatrics, Gentofte Hospital, University of Copenhagen, Hellerup; Dept. of Organic Chemistry, Royal Danish School of Pharmacy, Copenhagen, Denmark; Dept. of Medicine P, Division of Gastroenterology, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark; Dept. of Clinical Pharmacology, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark
,
L. B. Lassen Dept. of Medicine, Community Hospital, Elsinore; Dept. of Medical Gastroenterology C, Herlev, University of Copenhagen, Herlev; Dept. of Pediatrics, Aalborg Hospital, Aalborg; Dept. of Pediatrics, Viborg Hospital, Viborg; Dept. of Pediatrics, Gentofte Hospital, University of Copenhagen, Hellerup; Dept. of Organic Chemistry, Royal Danish School of Pharmacy, Copenhagen, Denmark; Dept. of Medicine P, Division of Gastroenterology, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark; Dept. of Clinical Pharmacology, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark
,
V. Binder Dept. of Medicine, Community Hospital, Elsinore; Dept. of Medical Gastroenterology C, Herlev, University of Copenhagen, Herlev; Dept. of Pediatrics, Aalborg Hospital, Aalborg; Dept. of Pediatrics, Viborg Hospital, Viborg; Dept. of Pediatrics, Gentofte Hospital, University of Copenhagen, Hellerup; Dept. of Organic Chemistry, Royal Danish School of Pharmacy, Copenhagen, Denmark; Dept. of Medicine P, Division of Gastroenterology, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark; Dept. of Clinical Pharmacology, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark
,
P. A. Krasilnikoff Dept. of Medicine, Community Hospital, Elsinore; Dept. of Medical Gastroenterology C, Herlev, University of Copenhagen, Herlev; Dept. of Pediatrics, Aalborg Hospital, Aalborg; Dept. of Pediatrics, Viborg Hospital, Viborg; Dept. of Pediatrics, Gentofte Hospital, University of Copenhagen, Hellerup; Dept. of Organic Chemistry, Royal Danish School of Pharmacy, Copenhagen, Denmark; Dept. of Medicine P, Division of Gastroenterology, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark; Dept. of Clinical Pharmacology, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark
,
P. Danø Dept. of Medicine, Community Hospital, Elsinore; Dept. of Medical Gastroenterology C, Herlev, University of Copenhagen, Herlev; Dept. of Pediatrics, Aalborg Hospital, Aalborg; Dept. of Pediatrics, Viborg Hospital, Viborg; Dept. of Pediatrics, Gentofte Hospital, University of Copenhagen, Hellerup; Dept. of Organic Chemistry, Royal Danish School of Pharmacy, Copenhagen, Denmark; Dept. of Medicine P, Division of Gastroenterology, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark; Dept. of Clinical Pharmacology, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark
,
S. Honoré Hansen Dept. of Medicine, Community Hospital, Elsinore; Dept. of Medical Gastroenterology C, Herlev, University of Copenhagen, Herlev; Dept. of Pediatrics, Aalborg Hospital, Aalborg; Dept. of Pediatrics, Viborg Hospital, Viborg; Dept. of Pediatrics, Gentofte Hospital, University of Copenhagen, Hellerup; Dept. of Organic Chemistry, Royal Danish School of Pharmacy, Copenhagen, Denmark; Dept. of Medicine P, Division of Gastroenterology, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark; Dept. of Clinical Pharmacology, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark
,
S. Nørby Rasmussen Dept. of Medicine, Community Hospital, Elsinore; Dept. of Medical Gastroenterology C, Herlev, University of Copenhagen, Herlev; Dept. of Pediatrics, Aalborg Hospital, Aalborg; Dept. of Pediatrics, Viborg Hospital, Viborg; Dept. of Pediatrics, Gentofte Hospital, University of Copenhagen, Hellerup; Dept. of Organic Chemistry, Royal Danish School of Pharmacy, Copenhagen, Denmark; Dept. of Medicine P, Division of Gastroenterology, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark; Dept. of Clinical Pharmacology, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark
&
E. F. Hvidberg Dept. of Medicine, Community Hospital, Elsinore; Dept. of Medical Gastroenterology C, Herlev, University of Copenhagen, Herlev; Dept. of Pediatrics, Aalborg Hospital, Aalborg; Dept. of Pediatrics, Viborg Hospital, Viborg; Dept. of Pediatrics, Gentofte Hospital, University of Copenhagen, Hellerup; Dept. of Organic Chemistry, Royal Danish School of Pharmacy, Copenhagen, Denmark; Dept. of Medicine P, Division of Gastroenterology, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark; Dept. of Clinical Pharmacology, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark
 show all
Pages 693-700 | Received 18 Dec 1985, Accepted 15 Jan 1986, Published online: 08 Jul 2009

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O. H. Nielsen, P. N. Bouchelouche, D. Berild & I. Ahnfelt-Rønne. (1993) Effect of 5-Aminosalicylic Acid and Analogous Substances on Superoxide Generation and Intracellular Free Calcium in Human Neutrophilic Granulocytes. Scandinavian Journal of Gastroenterology 28:6, pages 527-532.
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S. Almer, B. Norlander, M. Ström & H. Osterwald. (1991) Steady-State Pharmacokinetics of a New 4-Gram 5-Aminosalicylic Acid Retention Enema in Patients with Ulcerative Colitis in Remission. Scandinavian Journal of Gastroenterology 26:3, pages 327-335.
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M. C. M. Rijk, A. Van Schaik & J. H. M. Van Tongeren. (1988) Disposition of 5-Aminosalicylic Acid by 5-Aminosalicylic Acid-Delivering Compounds. Scandinavian Journal of Gastroenterology 23:sup148, pages 54-59.
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. (1988) Introduction. Scandinavian Journal of Gastroenterology 23:sup150, pages 3-21.
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M. C. M. Rijk, A. Van Schaik & J.H. M. Van Tongeren. (1988) Disposition of 5-Aminosalicylic Acid by 5-Aminosalicylic Acid-Delivering Compounds. Scandinavian Journal of Gastroenterology 23:1, pages 107-112.
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S. N. Rasmussen, K. Lauritsen, U. Tage-Jensen, O. H. Nielsen, P. Bytzer, O. Jacobsen, K. Ladefoged, M. Vilien, V. Binder, J. Rask-Madsen, S. Bondesen, S. Honore Hansen & E. F. Hvidberg. (1987) 5-Aminosalicylic Acid in the Treatment of Crohn's Disease: A 16-Week Double-Blind, Placebo-Controlled, Multicentre Study with Pentasa®. Scandinavian Journal of Gastroenterology 22:7, pages 877-883.
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Lisbet Ambrosius Christensen, Steen Nøby Rasmussen, Steen Honoré Hansen, Stig Bondesen & Eigill G. Hvidberg. (1987) Salazosulfa Pyridine and Metabolites in Fetal and Maternal Body Fluids with Special Reference to 5-Aminosalicylic Acid. Acta Obstetricia et Gynecologica Scandinavica 66:5, pages 433-435.
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