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Review Article

Roles of the Different Isozymes and Salivary Factors in the Maintenance of Optimal Conditions in the Gastrointestinal Canal

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Pages 305-317 | Published online: 08 Jul 2009

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Erik R Swenson. (2014) Safety of carbonic anhydrase inhibitors. Expert Opinion on Drug Safety 13:4, pages 459-472.
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Elif Akın Kazancıoğlu, Murat Güney, Murat Şentürk & Claudiu T. Supuran. (2012) Simple methanesulfonates are hydrolyzed by the sulfatase carbonic anhydrase activity. Journal of Enzyme Inhibition and Medicinal Chemistry 27:6, pages 880-885.
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Deniz Ekinci, Namudar I. Kurbanoglu, Emine Salamcı, Murat Şentürk & Claudiu T. Supuran. (2012) Carbonic anhydrase inhibitors: inhibition of human and bovine isoenzymes by benzenesulphonamides, cyclitols and phenolic compounds. Journal of Enzyme Inhibition and Medicinal Chemistry 27:6, pages 845-848.
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Deniz Ekinci, Mariya al-Rashida, Ghulam Abbas, Murat Şentürk & Claudiu T. Supuran. (2012) Chromone containing sulfonamides as potent carbonic anhydrase inhibitors. Journal of Enzyme Inhibition and Medicinal Chemistry 27:5, pages 744-747.
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Murat Şentürk, Deniz Ekinci, Süleyman Göksu & Claudiu T. Supuran. (2012) Effects of dopaminergic compounds on carbonic anhydrase isozymes I, II, and VI. Journal of Enzyme Inhibition and Medicinal Chemistry 27:3, pages 365-369.
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Hüseyin Çavdar, Deniz Ekinci, Oktay Talaz, Nurullah Saraçoğlu, Murat Şentürk & Claudiu T. Supuran. (2012) α-Carbonic anhydrases are sulfatases with cyclic diol monosulfate esters. Journal of Enzyme Inhibition and Medicinal Chemistry 27:1, pages 148-154.
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Ashok Aspatwar, Martti E. E. Tolvanen, Harlan Barker, Leo Syrjänen, Susanna Valanne, Sami Purmonen, Abdul Waheed, William S. Sly & Seppo Parkkila. (2022) Carbonic anhydrases in metazoan model organisms: molecules, mechanisms, and physiology. Physiological Reviews 102:3, pages 1327-1383.
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Seppo Parkkila. 2021. The Carbonic Anhydrases: Current and Emerging Therapeutic Targets. The Carbonic Anhydrases: Current and Emerging Therapeutic Targets 13 36 .
Kanij Rukshana Sumi, Soo Cheol Kim, Sathishkumar Natarajan, Kap Seong Choi, Myeong Rak Choi, Hoy-Taek Kim, Jong-In Park, Ill-Sup Nou, Kathleen M. Gilmour & Kang Hee Kho. (2018) Molecular cloning and characterization of secretory carbonic anhydrase VI in pufferfish ( Takifugu rubripes ). Gene 640, pages 57-65.
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Petrus Järvinen, Antti J. Kivelä, Pirjo Nummela, Anna Lepistö, Ari Ristimäki & Seppo Parkkila. (2017) Carbonic anhydrase II: a novel biomarker for pseudomyxoma peritonei. APMIS 125:3, pages 207-212.
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Maarit S. Patrikainen, Peiwen Pan, Harlan R. Barker & Seppo Parkkila. (2016) Altered gene expression in the lower respiratory tract of Car6 −/− mice. Transgenic Research 25:5, pages 649-664.
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Hang-kin Kong, Ka-Hing Wong & Samuel Chun-lap Lo. (2016) Identification of peptides released from hot water insoluble fraction of edible bird's nest under simulated gastro-intestinal conditions. Food Research International 85, pages 19-25.
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Taner Arabacı, Yasin Çiçek, Şükrü Beydemir, Cenk Fatih Çanakçı & Varol Çanakçı. (2015) Are increased salivary carbonic anhydrase VI levels related to the amount of supragingival dental calculus formation and clinical periodontal scores?. Journal of Dental Sciences 10:2, pages 123-127.
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Mustafa Durgun, Hasan Turkmen, Mariangela Ceruso & Claudiu T. Supuran. (2015) Synthesis of Schiff base derivatives of 4-(2-aminoethyl)-benzenesulfonamide with inhibitory activity against carbonic anhydrase isoforms I, II, IX and XII. Bioorganic & Medicinal Chemistry Letters 25:11, pages 2377-2381.
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Ashok Aspatwar, Martti E.E. Tolvanen, Harlan Barker & Seppo Parkkila. 2015. Carbonic Anhydrases as Biocatalysts. Carbonic Anhydrases as Biocatalysts 207 219 .
Jukka Leinonen & Seppo Parkkila. 2015. Carbonic Anhydrases as Biocatalysts. Carbonic Anhydrases as Biocatalysts 139 149 .
Maarit Patrikainen, Peiwen Pan, Natalia Kulesskaya, Vootele Voikar & Seppo Parkkila. (2014) The role of carbonic anhydrase VI in bitter taste perception: evidence from the Car6−/− mouse model. Journal of Biomedical Science 21:1.
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Abdul Waheed & William S. Sly. 2014. Carbonic Anhydrase: Mechanism, Regulation, Links to Disease, and Industrial Applications. Carbonic Anhydrase: Mechanism, Regulation, Links to Disease, and Industrial Applications 157 179 .
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Ramazan Demirdağ, Veysel Çomaklı, Murat Şentürk, Deniz Ekinci, Ö. İrfan Küfrevioğlu & Claudiu T. Supuran. (2013) Purification and characterization of carbonic anhydrase from sheep kidney and effects of sulfonamides on enzyme activity. Bioorganic & Medicinal Chemistry 21:6, pages 1522-1525.
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Chia‐Ming Liu, Yueh‐Min Lin, Kun‐Tu Yeh, Mu‐Kuan Chen, Jer‐Hwa Chang, Chih‐Jung Chen, Ming‐Yung Chou, Shun‐Fa Yang & Ming‐Hsien Chien. (2012) Expression of carbonic anhydrases I/II and the correlation to clinical aspects of oral squamous cell carcinoma analyzed using tissue microarray. Journal of Oral Pathology & Medicine 41:7, pages 533-539.
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Halis T. Balaydın, Murat Şentürk & Abdullah Menzek. (2012) Synthesis and carbonic anhydrase inhibitory properties of novel cyclohexanonyl bromophenol derivatives. Bioorganic & Medicinal Chemistry Letters 22:3, pages 1352-1357.
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Nikki Johnston. 2013. Gastroesophageal Reflux and the Lung. Gastroesophageal Reflux and the Lung 23 41 .
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Giulia Malaguarnera. (2011) Markers of bile duct tumors. World Journal of Gastrointestinal Oncology 3:4, pages 49.
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Fatemeh Bootorabi, Joonas Haapasalo, Elona Smith, Hannu Haapasalo & Seppo Parkkila. (2011) Carbonic anhydrase VII–a potential prognostic marker in gliomas. Health 03:01, pages 6-12.
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Hyung Ro Chu. (2009) Pathophysiology of Laryngopharyngeal Reflux Disease(LPRD). Journal of Clinical Otolaryngology Head and Neck Surgery 20:1, pages 3-8.
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Murat Şentürk, İlhami Gülçin, Arif Daştan, Ö. İrfan Küfrevioğlu & Claudiu T. Supuran. (2009) Carbonic anhydrase inhibitors. Inhibition of human erythrocyte isozymes I and II with a series of antioxidant phenols. Bioorganic & Medicinal Chemistry 17:8, pages 3207-3211.
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Marcus Mau, Thomas M. Kaiser & Karl-Heinz Südekum. (2009) Evidence for the presence of carbonic anhydrase 29-kDa isoenzyme in salivary secretions of three ruminating species and the gelada baboon. Archives of Oral Biology 54:4, pages 354-360.
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Laura Kummola, Jonna M Hämäläinen, Jyrki Kivelä, Antti J Kivelä, Juha Saarnio, Tuomo Karttunen & Seppo Parkkila. (2005) Expression of a novel carbonic anhydrase, CA XIII, in normal and neoplastic colorectal mucosa. BMC Cancer 5:1.
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Antti J. Kivelä. (2005) Carbonic anhydrases in normal gastrointestinal tract and gastrointestinal tumours. World Journal of Gastroenterology 11:2, pages 155.
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Vibeke Sødring Elbrønd, Carolyn J.P Jones & Erik Skadhauge. (2004) Localization, morphology and function of the mitochondria-rich cells in relation to transepithelial Na+-transport in chicken lower intestine (coprodeum). Comparative Biochemistry and Physiology Part A: Molecular & Integrative Physiology 137:4, pages 683-696.
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Piia Halmi, Jonna Lehtonen, Abdul Waheed, William S. Sly & Seppo Parkkila. (2004) Expression of hypoxia-inducible, membrane-bound carbonic anhydrase isozyme XII in mouse tissues. The Anatomical Record 277A:1, pages 171-177.
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J. LiE.J. HelmerhorstR.F. TroxlerF.G. Oppenheim. (2016) Identification of in vivo Pellicle Constituents by Analysis of Serum Immune Responses . Journal of Dental Research 83:1, pages 60-64.
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H. Rodig, P. Brust, J. Römer, H. Kasch, R. Bergmann, F. Füchtner, J. Steinbach & B. Johannsen. 2002. Brain Imaging Using PET. Brain Imaging Using PET 219 226 .
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Juha Saarnio, Seppo Parkkila, Anna-Kaisa Parkkila, Silvia Pastoreková, Kari Haukipuro, Jaromir Pastorek, Tatu Juvonen & Tuomo J Karttunen. (2001) Transmembrane carbonic anhydrase, MN/CA IX, is a potential biomarker for biliary tumours. Journal of Hepatology 35:5, pages 643-649.
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Seppo Parkkila, Anna-Kaisa Parkkila, Hannu Rajaniemi, Gul N. Shah, Jeffrey H. Grubb, Abdul Waheed & William S. Sly. (2001) Expression of membrane-associated carbonic anhydrase XIV on neurons and axons in mouse and human brain. Proceedings of the National Academy of Sciences 98:4, pages 1918-1923.
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M. Said Ghandour, Anna‐Kaisa Parkkila, Seppo Parkkila, Abdul Waheed & William S. Sly. (2002) Mitochondrial Carbonic Anhydrase in the Nervous System. Journal of Neurochemistry 75:5, pages 2212-2220.
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Robert I. Henkin, Martin Brian M.Agarwal Raghunath P.. (1999) Decreased Parotid Saliva Gustin/Carbonic Anhydrase VI Secretion: An Enzyme Disorder Manifested by Gustatory and Olfactory Dysfunction. The American Journal of the Medical Sciences 318:6, pages 380-391.
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Jyrki Kivelä, Seppo Parkkila, Anna‐Kaisa Parkkila, Jukka Leinonen & Hannu Rajaniemi. (2004) Salivary carbonic anhydrase isoenzyme VI. The Journal of Physiology 520:2, pages 315-320.
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Anna-Kaisa Parkkila, Anna L. Scarim, Seppo Parkkila, Abdul Waheed, John A. Corbett & William S. Sly. (1998) Expression of Carbonic Anhydrase V in Pancreatic Beta Cells Suggests Role for Mitochondrial Carbonic Anhydrase in Insulin Secretion. Journal of Biological Chemistry 273:38, pages 24620-24623.
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Juha Saarnio, Seppo Parkkila, Anna-Kaisa Parkkila, Abdul Waheed, Matthew C. Casey, Xiao Yan Zhou, Silvia Pastoreková, Jaromir Pastorek, Tuomo Karttunen, Kari Haukipuro, Matti I. Kairaluoma & William S. Sly. (2016) Immunohistochemistry of Carbonic Anhydrase Isozyme IX (MN/CA IX) in Human Gut Reveals Polarized Expression in the Epithelial Cells with the Highest Proliferative Capacity. Journal of Histochemistry & Cytochemistry 46:4, pages 497-504.
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