Citations (20)
Keep up to date with the latest research on this topic with citation updates for this article.
Read on this site (5)
Lesley A. Stanley & C. Roland Wolf. (2022) Through a glass, darkly? HepaRG and HepG2 cells as models of human phase I drug metabolism. Drug Metabolism Reviews 54:1, pages 46-62.
Read now
Read now
Haruka Tsutsui, Motohiro Kato, Shino Kuramoto, Nobuo Sekiguchi, Hidetoshi Shindoh & Kazuhisa Ozeki. (2020) Quantitative evaluation of hepatic and intestinal induction of CYP3A in clinical practice. Xenobiotica 50:8, pages 875-884.
Read now
Read now
Lunzhi Yuan, Xuan Liu, Liang Zhang, Yali Zhang, Yao Chen, Xiaoling Li, Kun Wu, Jiali Cao, Wangheng Hou, Yuqiong Que, Jun Zhang, Hua Zhu, Quan Yuan, Qiyi Tang, Tong Cheng & Ningshao Xia. (2018) Optimized HepaRG is a suitable cell source to generate the human liver chimeric mouse model for the chronic hepatitis B virus infection. Emerging Microbes & Infections 7:1, pages 1-17.
Read now
Read now
James J Cali, Dongping Ma, Monika G Wood, Poncho L Meisenheimer & Dieter H Klaubert. (2012) Bioluminescent assays for ADME evaluation: dialing in CYP selectivity with luminogenic substrates. Expert Opinion on Drug Metabolism & Toxicology 8:9, pages 1115-1130.
Read now
Read now
A. Kaneko, M. Kato, C. Endo, K. Nakano, M. Ishigai & K. Takeda. (2010) Prediction of clinical CYP3A4 induction using cryopreserved human hepatocytes. Xenobiotica 40:12, pages 791-799.
Read now
Read now
Articles from other publishers (14)
Maria Carolina Stipp, Juliana Danna Kulik, Claudia Rita Corso, Claudia Martins Galindo, Eliana Rezende Adami, Alberto Gonçalves Evangelista, Fernando Bittencourt Luciano, Sheila Maria Brochado Winnischofer, Silvia Maria Suter Correia Cadena, Guilherme Lanzi Sassaki & Alexandra Acco. (2023) Influence of red wine polysaccharides on cytochrome P450 enzymes and inflammatory parameters in tumor models. International Journal of Biological Macromolecules 240, pages 124385.
Crossref
Crossref
Chihiro Endo-Tsukude, Motohiro Kato, Akihisa Kaneko, Satofumi Iida, Shino Kuramoto, Masaki Ishigai & Akinobu Hamada. (2019) Risk of CYP2C9 induction analyzed by a relative factor approach with human hepatocytes. Drug Metabolism and Pharmacokinetics 34:5, pages 325-333.
Crossref
Crossref
Lor Huai Chong, Celine Ng, Huan Li, Edmund Feng Tian, Abhishek Ananthanarayanan, Michael McMillian & Yi-Chin Toh. (2019) Hepatic Bioactivation of Skin-Sensitizing Drugs to Immunogenic Reactive Metabolites. ACS Omega 4:9, pages 13902-13912.
Crossref
Crossref
Theodore P. RasmussenAndré Guillouzo & Christiane Guguen‐Guillouzo. 2018. Stem Cells in Birth Defects Research and Developmental Toxicology. Stem Cells in Birth Defects Research and Developmental Toxicology
309
339
.
Zhen Ren, Si Chen, Baitang Ning & Lei Guo. 2018. Drug-Induced Liver Toxicity. Drug-Induced Liver Toxicity
151
177
.
Shino Kuramoto, Motohiro Kato, Hidetoshi Shindoh, Akihisa Kaneko, Masaki Ishigai & Seiji Miyauchi. (2017)
Simple Evaluation Method for CYP3A4 Induction from Human Hepatocytes: The Relative Factor Approach with an Induction Detection Limit Concentration Based on the
E
max
Model
. Drug Metabolism and Disposition 45:11, pages 1139-1145.
Crossref
Crossref
Barry C. Jones, Helen Rollison, Susanne Johansson, Kajsa P. Kanebratt, Craig Lambert, Karthick Vishwanathan & Tommy B. Andersson. (2017) Managing the Risk of CYP3A Induction in Drug Development: A Strategic Approach. Drug Metabolism and Disposition 45:1, pages 35-41.
Crossref
Crossref
M. Nagai, Y. Konno, M. Satsukawa, S. Yamashita & K. Yoshinari. (2016) Establishment of In Silico Prediction Models for CYP3A4 and CYP2B6 Induction in Human Hepatocytes by Multiple Regression Analysis Using Azole Compounds. Drug Metabolism and Disposition 44:8, pages 1390-1398.
Crossref
Crossref
Ana Ferreira, Márcio Rodrigues, Samuel Silvestre, Amílcar Falcão & Gilberto Alves. (2014) HepaRG cell line as an in vitro model for screening drug–drug interactions mediated by metabolic induction: Amiodarone used as a model substance. Toxicology in Vitro 28:8, pages 1531-1535.
Crossref
Crossref
Haifang Guo, Can Liu, Jia Li, Mian Zhang, Mengyue Hu, Ping Xu, Li Liu & Xiaodong Liu. (2013) A Mechanistic Physiologically Based Pharmacokinetic-Enzyme Turnover Model Involving both Intestine and Liver to Predict CYP3A Induction-Mediated Drug–Drug Interactions. Journal of Pharmaceutical Sciences 102:8, pages 2819-2836.
Crossref
Crossref
Naoki Kotani, Kazuya Maeda, Yasuyuki Debori, Sandrine Camus, Ruoya Li, Christophe Chesne & Yuichi Sugiyama. (2012) Expression and Transport Function of Drug Uptake Transporters in Differentiated HepaRG Cells. Molecular Pharmaceutics 9:12, pages 3434-3441.
Crossref
Crossref
Sébastien Anthérieu, Christophe Chesné, Ruoya Li, Christiane Guguen-Guillouzo & André Guillouzo. (2012) Optimization of the HepaRG cell model for drug metabolism and toxicity studies. Toxicology in Vitro 26:8, pages 1278-1285.
Crossref
Crossref
Alexander V. LyubimovHiroshi Komura & Masahiro Iwaki. 2011. Encyclopedia of Drug Metabolism and Interactions. Encyclopedia of Drug Metabolism and Interactions
1
41
.
Toshito Nakagawa. (2010) Prediction of the pharmacokinetics of clinical candidates in humans from in vitro data.. Folia Pharmacologica Japonica 135:2, pages 84-86.
Crossref
Crossref