Citations (37)
Keep up to date with the latest research on this topic with citation updates for this article.
Read on this site (3)
Jie Zhang, Petr Pavek, Rajamanikkam Kamaraj, Li Ren & Tiehua Zhang. (2023) Dietary phytochemicals as modulators of human pregnane X receptor. Critical Reviews in Food Science and Nutrition 63:19, pages 3279-3301.
Read now
Read now
Skyler H. Hoang, Kevin M. Tveter, Esther Mezhibovsky & Diana E. Roopchand. (2023) Proanthocyanidin B2 derived metabolites may be ligands for bile acid receptors S1PR2, PXR and CAR: an in silico approach. Journal of Biomolecular Structure and Dynamics 0:0, pages 1-14.
Read now
Read now
Congyang Ding, Yajing Li, Xiao Li, Lu Meng, Ran Fu, Xiaonan Wang, Ying Li, Yinling Ma & Zhanjun Dong. (2022) QiShenYiQi pills, a Chinese patent medicine, increase bioavailability of atorvastatin by inhibiting Mrp2 expression in rats. Pharmaceutical Biology 60:1, pages 185-194.
Read now
Read now
Articles from other publishers (34)
Hai‐Guo Su, Hang‐Fei Liang, Gui‐Lin Hu, Lin Zhou, Xing‐Rong Peng, Hui‐Chang Bi & Ming‐Hua Qiu. (2022)
Applanoids A—E as the First Examples of C‐15/C‐20 Michael Adducts in
Ganoderma
Triterpenoids and Their
PXR
Agonistic Activity
. Chinese Journal of Chemistry 40:22, pages 2633-2641.
Crossref
Crossref
Ying Zhang, Zishen Lin, Lixue Wang, Xiangyue Guo, Zhihui Hao, Zhen Li, Lee J. Johnston & Bing Dong. (2022) Cooperative Interaction of Phenolic Acids and Flavonoids Contained in Activated Charcoal with Herb Extracts, Involving Cholesterol, Bile Acid, and FXR/PXR Activation in Broilers Fed with Mycotoxin-Containing Diets. Antioxidants 11:11, pages 2200.
Crossref
Crossref
Jing-Yun Dou, Min Zhang, Huan Cen, Yi-Qin Chen, Yi-Fan Wu, Fuhua Lu, Jiuyao Zhou, Xu-Sheng Liu & Yue-Yu Gu. (2022) Salvia miltiorrhiza Bunge (Danshen) and Bioactive Compound Tanshinone IIA Alleviates Cisplatin-Induced Acute Kidney Injury Through Regulating PXR/NF-κB Signaling. Frontiers in Pharmacology 13.
Crossref
Crossref
Apisada Jiso, Phisit Khemawoot, Pinnakarn Techapichetvanich, Sutinee Soopairin, Kittiphong Phoemsap, Panrawee Damrongsakul, Supakit Wongwiwatthananukit & Pornpun Vivithanaporn. (2022) Drug-Herb Interactions among Thai Herbs and Anticancer Drugs: A Scoping Review. Pharmaceuticals 15:2, pages 146.
Crossref
Crossref
Ying-huan Hu, Deng-ke Li, Zheng-yang Quan, Cheng-yu Wang, Ming Zhou & Zhen-xiao Sun. (2021) Exploration of components and mechanisms of Polygoni Multiflori Radix-induced hepatotoxicity using siRNA -mediated CYP3A4 or UGT1A1 knockdown liver cells. Journal of Ethnopharmacology 270, pages 113845.
Crossref
Crossref
Martine Daujat-Chavanieu & Sabine Gerbal-Chaloin. (2020) Regulation of CAR and PXR Expression in Health and Disease. Cells 9:11, pages 2395.
Crossref
Crossref
Tao-Li Liu, Li-Na Zhang, Yue-Yu Gu, Mei-Gui Lin, Jun Xie, Yu-ling Chen, Jia-Hui Liu, Xin-Lin Wu & Sui-Lin Mo. (2020)
The Synergistic Antitumor Effect of Tanshinone IIA Plus Adriamycin on Human Hepatocellular Carcinoma Xenograft in BALB/C Nude Mice and Their Influences on Cytochrome P450 CYP3A4
In Vivo
. Advances in Medicine 2020, pages 1-15.
Crossref
Crossref
XunLi, Yingjiao Liu, Shifeng Chu, Songwei Yang, Ye Peng, Siyu Ren, Birui Wen & Naihong Chen. (2019) Physcion and physcion 8-O-β-glucopyranoside: A review of their pharmacology, toxicities and pharmacokinetics. Chemico-Biological Interactions 310, pages 108722.
Crossref
Crossref
Md. Moshfekus Saleh-e-In, Ayan Roy, Muhammad Abdullah Al-Mansur, Choudhury Mahmood Hasan, Md. Matiur Rahim, Nasim Sultana, Shamim Ahmed, Md. Rabiul Islam & Johannes van Staden. (2019) Isolation and in silico prediction of potential drug-like compounds from Anethum sowa L. root extracts targeted towards cancer therapy. Computational Biology and Chemistry 78, pages 242-259.
Crossref
Crossref
Da-Cheng Hao. 2019. Ranunculales Medicinal Plants. Ranunculales Medicinal Plants
125
173
.
Fengling Wang, Yifan Wu, Xiaoting Xie, Jing Sun & Weidong Chen. (2018) Essential role of nuclear receptors for the evaluation of the benefits of bioactive herbal extracts on liver function. Biomedicine & Pharmacotherapy 99, pages 798-809.
Crossref
Crossref
Yuhua Li, Ling Huang, Jiahong Sun, Xiaohua Wei, Jinhua Wen, Guoping Zhong, Min Huang & Huichang Bi. (2017) Mulberroside A suppresses PXR-mediated transactivation and gene expression of P-gp in LS174T cells. Journal of Biochemical and Molecular Toxicology 31:5, pages e21884.
Crossref
Crossref
Moon Hee Lee, Min Ho Han, Dae-Sung Lee, Cheol Park, Su-Hyun Hong, Gi-Young Kim, Sang Hoon Hong, Kyoung Seob Song, Il-Whan Choi, Hee-Jae Cha & Yung Hyun Choi. (2017) Morin exerts cytoprotective effects against oxidative stress in C2C12 myoblasts via the upregulation of Nrf2-dependent HO-1 expression and the activation of the ERK pathway. International Journal of Molecular Medicine 39:2, pages 399-406.
Crossref
Crossref
Chenshu Xu, Min Huang & Huichang Bi. (2016) PXR- and CAR-mediated herbal effect on human diseases. Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms 1859:9, pages 1121-1129.
Crossref
Crossref
Wanghui Jing, Ruilin Liu, Wei Du, Zhimin Luo, Pengqi Guo, Ting Zhang, Aiguo Zeng, Chun Chang & Qiang Fu. (2016) Pharmacokinetic and Metabolic Characteristics of Herb-Derived Khellactone Derivatives, A Class of Anti-HIV and Anti-Hypertensive: A Review. Molecules 21:3, pages 314.
Crossref
Crossref
Ling Li, François Bonneton, Xiao Yong Chen & Vincent Laudet. (2015) Botanical compounds and their regulation of nuclear receptor action: The case of traditional Chinese medicine. Molecular and Cellular Endocrinology 401, pages 221-237.
Crossref
Crossref
LE-LE GE, LIAN-DI KAN, ZHENG-BING ZHUGE, KE MA & SHU-QING CHEN. (2015) Ophiopogon japonicus strains from different cultivation regions exhibit markedly different properties on cytotoxicity, pregnane X receptor activation and cytochrome P450 3A4 induction. Biomedical Reports 3:3, pages 430-434.
Crossref
Crossref
Hyun-Jong Cho & In-Soo Yoon. (2015) Pharmacokinetic Interactions of Herbs with Cytochrome P450 and P-Glycoprotein. Evidence-Based Complementary and Alternative Medicine 2015, pages 1-10.
Crossref
Crossref
Koichi Handa, Izumi Nakagome, Noriyuki Yamaotsu, Hiroaki Gouda & Shuichi Hirono. (2015) Three-Dimensional Quantitative Structure–Activity Relationship Analysis for Human Pregnane X Receptor for the Prediction of CYP3A4 Induction in Human Hepatocytes: Structure-Based Comparative Molecular Field Analysis. Journal of Pharmaceutical Sciences 104:1, pages 223-232.
Crossref
Crossref
Rongrong Deng, Chenshu Xu, Xiao Chen, Pan Chen, Yongtao Wang, Xunian Zhou, Jing Jin, Lu Niu, Mengjia Ying, Min Huang & Huichang Bi. (2014) Resveratrol Suppresses the Inducible Expression of CYP3A4 Through the Pregnane X Receptor. Journal of Pharmacological Sciences 126:2, pages 146-154.
Crossref
Crossref
Stalin Selvaraj, Ramya Ramanathan, Varshini Vasudevaraja, Kalpoondi Sekar Rajan, Sridharan Krishnaswamy, Brindha Pemiah, Swaminathan Sethuraman, Vigneshwar Ramakrishnan & Uma Maheswari Krishnan. (2014) Transcriptional regulation of the pregnane-X receptor by the Ayurvedic formulation Chandraprabha Vati. RSC Adv. 4:110, pages 64967-64976.
Crossref
Crossref
Vijay Rathod, Sumit Jain, Prajwal Nandekar & Abhay T. Sangamwar. (2014) Human pregnane X receptor: a novel target for anticancer drug development. Drug Discovery Today 19:1, pages 63-70.
Crossref
Crossref
Ákos Tarcsay & György M. Keserű. 2014. Protein Modelling. Protein Modelling
287
322
.
Monimoy Banerjee & Taosheng Chen. (2013) Differential regulation of CYP3A4 promoter activity by a new class of natural product derivatives binding to pregnane X receptor. Biochemical Pharmacology 86:6, pages 824-835.
Crossref
Crossref
Ling Huang, Min Huang, Yu-Hua Li, Rui-Ming Li, Yu Zeng, Shao-Yi Kuang, Li Zhang, Yi-Tao Wang & Hui-Chang Bi. (2013) Up-regulatation of CYP3A expression through pregnent X receptor by praeruptorin D isolated from Peucedanum praeruptorum Dunn. Journal of Ethnopharmacology 148:2, pages 596-602.
Crossref
Crossref
Yongli Zhang, Ling Huang, Huichang Bi, Yuqiang Cui, Jingqing Li, Xiangsheng Wang, Xiaoling Qin, Jiangying Chen & Min Huang. (2012) Study of the upregulation of the activity of cytochrome P450 3A isoforms by Astragalus injection and Astragalus granules in rats and in cells. European Journal of Drug Metabolism and Pharmacokinetics 38:2, pages 105-113.
Crossref
Crossref
Ling Huang, Qian Wu, Yu-Hua Li, Yi-Tao Wang & Hui-Chang Bi. (2013)
PXR-Mediated Upregulation of CYP3A Expression by Herb Compound Praeruptorin C from
Peucedanum praeruptorum
Dunn
. Evidence-Based Complementary and Alternative Medicine 2013, pages 1-9.
Crossref
Crossref
John H. K. Yeung. 2013. Evidence and Rational Based Research on Chinese Drugs. Evidence and Rational Based Research on Chinese Drugs
237
282
.
Wen-yu Wu & Yi-ping Wang. (2012) Pharmacological actions and therapeutic applications of Salvia miltiorrhiza depside salt and its active components. Acta Pharmacologica Sinica 33:9, pages 1119-1130.
Crossref
Crossref
Wei Dou, Subhajit Mukherjee, Hao Li, Madhukumar Venkatesh, Hongwei Wang, Sandhya Kortagere, Ariel Peleg, Sridhar S. Chilimuri, Zheng-Tao Wang, Ying Feng, Eric R. Fearon & Sridhar Mani. (2012) Alleviation of Gut Inflammation by Cdx2/Pxr Pathway in a Mouse Model of Chemical Colitis. PLoS ONE 7:7, pages e36075.
Crossref
Crossref
Aik Jiang Lau, Guixiang Yang, Chun Wei Yap & Thomas K. H. Chang. (2012) Selective Agonism of Human Pregnane X Receptor by Individual Ginkgolides. Drug Metabolism and Disposition 40:6, pages 1113-1121.
Crossref
Crossref
Shaojun Shi & Ulrich Klotz. (2012) Drug Interactions with Herbal Medicines. Clinical Pharmacokinetics 51:2, pages 77-104.
Crossref
Crossref
Gautier Moroy, Virginie Y. Martiny, Philippe Vayer, Bruno O. Villoutreix & Maria A. Miteva. (2012) Toward in silico structure-based ADMET prediction in drug discovery. Drug Discovery Today 17:1-2, pages 44-55.
Crossref
Crossref
Ci-Nong Chen, Yu-Hsuan Shih, Yi-Lung Ding & Max K. Leong. (2011) Predicting Activation of the Promiscuous Human Pregnane X Receptor by Pharmacophore Ensemble/Support Vector Machine Approach. Chemical Research in Toxicology 24:10, pages 1765-1778.
Crossref
Crossref