Citations (30)
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Hidetaka Kamimura, Shotaro Uehara, Nao Yoneda & Hiroshi Suemizu. (2023) Empirical scaling factor for predicting human pharmacokinetic profiles of disproportionate metabolites using the Css–MRTpo method and chimeric mice with humanised livers. Xenobiotica 53:8-9, pages 523-535.
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Alan J. Barnes, David R. Baker, Kirsten Hobby, Simon Ashton, Filippos Michopoulos, Konstantina Spagou, Neil J. Loftus & Ian D. Wilson. (2014) Endogenous and xenobiotic metabolite profiling of liver extracts from SCID and chimeric humanized mice following repeated oral administration of troglitazone. Xenobiotica 44:2, pages 174-185.
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Yoshiyuki Igawa, Tomomichi Fujitani, Bharti Shah, Charles Oo & Yasushi Kanai. (2014) In vitro and in vivo metabolism of a novel chymase inhibitor, SUN13834, and the predictability of human metabolism using mice with humanized liver. Xenobiotica 44:2, pages 154-163.
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Chiaki Tanoue, Kazumi Sugihara, Naoto Uramaru, Yoshitaka Tayama, Yoko Watanabe, Toru Horie, Shigeru Ohta & Shigeyuki Kitamura. (2013) Prediction of human metabolism of the sedative-hypnotic zaleplon using chimeric mice transplanted with human hepatocytes. Xenobiotica 43:11, pages 956-962.
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Katsutoshi Yoshizato & Chise Tateno. (2013) A mouse with humanized liver as an animal model for predicting drug effects and for studying hepatic viral infection: where to next?. Expert Opinion on Drug Metabolism & Toxicology 9:11, pages 1419-1435.
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Kristin Samuelsson, Kathryn Pickup, Sunil Sarda, John G. Swales, Yoshio Morikawa, Timothy Schulz-Utermoehl, Michael Hutchison & Ian D. Wilson. (2012) Pharmacokinetics and metabolism of midazolam in chimeric mice with humanised livers. Xenobiotica 42:11, pages 1128-1137.
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Articles from other publishers (21)
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Daigo Asano, Koichi Nakamura, Yumi Nishiya, Hideyuki Shiozawa, Hideo Takakusa, Takahiro Shibayama, Shin-ichi Inoue, Tsuyoshi Shinozuka, Takakazu Hamada, Chizuko Yahara, Nobuaki Watanabe & Kouichi Yoshinari. (2023)
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Anna Zerdoug, Marc Le Vée, Shotaro Uehara, Béatrice Lopez, Christophe Chesné, Hiroshi Suemizu & Olivier Fardel. (2022) Contribution of Humanized Liver Chimeric Mice to the Study of Human Hepatic Drug Transporters: State of the Art and Perspectives. European Journal of Drug Metabolism and Pharmacokinetics 47:5, pages 621-637.
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Satoshi Ito, Hidetaka Kamimura, Yousuke Yamamoto, Hiroyuki Chijiwa, Takeshi Okuzono, Hiroshi Suemizu & Hiroshi Yamazaki. (2020) Human plasma concentration-time profiles of troglitazone and troglitazone sulfate simulated by in vivo experiments with chimeric mice with humanized livers and semi-physiological pharmacokinetic modeling. Drug Metabolism and Pharmacokinetics 35:6, pages 505-514.
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Yuji Ishida, Chihiro Yamasaki, Hiroko Iwanari, Hisahiko Yamashita, Yuko Ogawa, Ami Yanagi, Suzue Furukawa, Yuha Kojima, Kazuaki Chayama, Junichi Kamiie & Chise Tateno. (2020) Detection of acute toxicity of aflatoxin B1 to human hepatocytes in vitro and in vivo using chimeric mice with humanized livers. PLOS ONE 15:9, pages e0239540.
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Jose Serrano, Richard C. Kolanczyk, Mark A. Tapper, Tylor Lahren, Nagaraju Dongari, Dean E. Hammermeister, Patricia A. Kosian, Patricia K. Schmieder, Barbara R. Sheedy, Katie Challis & Alena Kubátová. (2019) Characterization and analysis of estrogenic cyclic phenone metabolites produced in vitro by rainbow trout liver slices using GC-MS, LC-MS and LC-TOF-MS. Journal of Chromatography B 1126-1127, pages 121717.
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Kaito Nihira, Ken-ichiro Nan-ya, Masakazu Kakuni, Yoko Ono, Yukitaka Yoshikawa, Toshio Ota, Masanori Hiura & Kouichi Yoshinari. (2019) Chimeric Mice With Humanized Livers Demonstrate Human-Specific Hepatotoxicity Caused by a Therapeutic Antibody Against TRAIL-Receptor 2/Death Receptor 5. Toxicological Sciences 167:1, pages 190-201.
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Karl-Dimiter Bissig, Weiguo Han, Mercedes Barzi, Nataliia Kovalchuk, Liang Ding, Xiaoyu Fan, Francis P. Pankowicz, Qing-Yu Zhang & Xinxin Ding. (2018) P450-Humanized and Human Liver Chimeric Mouse Models for Studying Xenobiotic Metabolism and Toxicity. Drug Metabolism and Disposition 46:11, pages 1734-1744.
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Seigo Sanoh & Shigeru Ohta. (2018) Contribution of chimeric mice with a humanized liver to the evaluation of pharmacology, toxicity, and pharmacokinetics in drug discovery and development創薬におけるヒト肝細胞キメラマウスを用いた薬効，毒性および薬物動態評価の有用性. Folia Pharmacologica Japonica 151:5, pages 213-220.
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Richard Gallagher, Leonard Dillon, Aidan Grimsley, Jim Murphy, Kristin Samuelsson & David Douce. (2014) The application of a new microfluidic device for the simultaneous identification and quantitation of midazolam metabolites obtained from a single micro-litre of chimeric mice blood. Rapid Communications in Mass Spectrometry 28:11, pages 1293-1302.
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Seigo Sanoh & Shigeru Ohta. (2014) Chimeric mice transplanted with human hepatocytes as a model for prediction of human drug metabolism and pharmacokinetics. Biopharmaceutics & Drug Disposition 35:2, pages 71-86.
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John R. Foster, Matt Jacobsen, Gerry Kenna, Timothy Schulz-Utermoehl, Yoshio Morikawa, Juuso Salmu & Ian D. Wilson. (2012) Differential Effect of Troglitazone on the Human Bile Acid Transporters, MRP2 and BSEP, in the PXB Hepatic Chimeric Mouse. Toxicologic Pathology 40:8, pages 1106-1116.
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Masakazu Kakuni, Mayu Morita, Kentaro Matsuo, Yumiko Katoh, Miki Nakajima, Chise Tateno & Tsuyoshi Yokoi. (2012) Chimeric mice with a humanized liver as an animal model of troglitazone-induced liver injury. Toxicology Letters 214:1, pages 9-18.
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