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Xenobiotica
the fate of foreign compounds in biological systems
Volume 42, 2012 - Issue 12
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Molecular Toxicology

Acute arsenic toxicity alters cytochrome P450 and soluble epoxide hydrolase and their associated arachidonic acid metabolism in C57Bl/6 mouse heart

Anwar Anwar-MohamedFaculty of Pharmacy and Pharmaceutical Sciences, University of Alberta, Edmonton, Alberta, Canada
,
Ahmed A. El-SherbeniFaculty of Pharmacy and Pharmaceutical Sciences, University of Alberta, Edmonton, Alberta, Canada
,
Seok H. KimFaculty of Pharmacy and Pharmaceutical Sciences, University of Alberta, Edmonton, Alberta, Canada
,
Hassan N. AlthurwiFaculty of Pharmacy and Pharmaceutical Sciences, University of Alberta, Edmonton, Alberta, Canada
,
Beshay N. M. ZordokyFaculty of Pharmacy and Pharmaceutical Sciences, University of Alberta, Edmonton, Alberta, Canada
&
Ayman O. S. El-KadiFaculty of Pharmacy and Pharmaceutical Sciences, University of Alberta, Edmonton, Alberta, CanadaCorrespondence[email protected]
Pages 1235-1247 | Received 09 Mar 2012, Accepted 11 May 2012, Published online: 09 Jun 2012

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Mahmoud A. El-Ghiaty, Sara R. El-Mahrouk, Mohammed A. Alqahtani & Ayman O. S. El-Kadi. (2023) Differential modulation of cytochrome P450 enzymes by arsenicals in non-human experimental models. Drug Metabolism Reviews 55:4, pages 405-427.
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Ahmed A. El-Sherbeni & Ayman O. S. El-Kadi. (2017) Microsomal cytochrome P450 as a target for drug discovery and repurposing. Drug Metabolism Reviews 49:1, pages 1-17.
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Anwar Anwar-Mohamed, Ahmed El-Sherbeni, Seok Hee Kim, Osama H. Elshenawy, Hassan N. Althurwi, Beshay N. M. Zordoky & Ayman O. S. El-Kadi. (2013) Acute arsenic treatment alters cytochrome P450 expression and arachidonic acid metabolism in lung, liver and kidney of C57Bl/6 mice. Xenobiotica 43:8, pages 719-729.
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Articles from other publishers (18)

Alexa N. Carrera, Marianne K.O. Grant & Beshay N. Zordoky. (2020) CYP1B1 as a therapeutic target in cardio-oncology. Clinical Science 134:21, pages 2897-2927.
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José M. Torres-Arellano, Citlalli Osorio-Yáñez, Luz C. Sánchez-Peña, Julio C. Ayllon-Vergara, Laura Arreola-Mendoza, Guadalupe Aguilar-Madrid & Luz M. Del Razo. (2020) Natriuretic peptides and echocardiographic parameters in Mexican children environmentally exposed to arsenic. Toxicology and Applied Pharmacology 403, pages 115164.
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Hongjing Zhao, Yu Wang, Menghao Guo, Dongxue Fei, Mengyao Mu, Hongxian Yu & Mingwei Xing. (2019) Hepatoprotective effects of zinc (II) via cytochrome P-450/reactive oxygen species and canonical apoptosis pathways after arsenite waterborne exposure in common carp. Chemosphere 236, pages 124869.
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Bodhisattwa Mondal, Hongxia Chen, Weihua Wen, Ercole L. Cavalieri, Eleanor G. Rogan & Muhammad Zahid. (2018) Modulation of Cellular Response to Arsenic Trioxide Toxicity by Resveratrol. ACS Omega 3:5, pages 5511-5515.
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Chao-Yu Chen, Pinpin Lin, Ming-Hsien Tsai & Hui-Ling Lee. (2017) Targeted lipidomics profiling of acute arsenic exposure in mice serum by on-line solid-phase extraction stable-isotope dilution liquid chromatography–tandem mass spectrometry. Archives of Toxicology 91:9, pages 3079-3091.
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Lei Chen, Yu-Hang Zhang, Quan Zou, Chen Chu & Zhiliang Ji. (2016) Analysis of the chemical toxicity effects using the enrichment of Gene Ontology terms and KEGG pathways. Biochimica et Biophysica Acta (BBA) - General Subjects 1860:11, pages 2619-2626.
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Ahmed A. El-Sherbeni & Ayman O. S. El-Kadi. (2016) Repurposing Resveratrol and Fluconazole To Modulate Human Cytochrome P450-Mediated Arachidonic Acid Metabolism. Molecular Pharmaceutics 13:4, pages 1278-1288.
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Stephanie Seneff, Robert M. Davidson, Ann Lauritzen, Anthony Samsel & Glyn Wainwright. (2015) A novel hypothesis for atherosclerosis as a cholesterol sulfate deficiency syndrome. Theoretical Biology and Medical Modelling 12:1.
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David C. Ellinsworth. (2015) Arsenic, Reactive Oxygen, and Endothelial Dysfunction. Journal of Pharmacology and Experimental Therapeutics 353:3, pages 458-464.
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Anwar Anwar-MohamedOsama H. ElshenawyAhmed A. El-SherbeniMohamed AbdelradyAyman O.S. El-Kadi. (2014) Acute arsenic treatment alters arachidonic acid and its associated metabolite levels in the brain of C57Bl/6 mice. Canadian Journal of Physiology and Pharmacology 92:8, pages 693-702.
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You-Lin Tain, Steve Leu, Kay L. H. Wu, Wei-Chia Lee & Julie Y. H. Chan. (2014) Melatonin prevents maternal fructose intake-induced programmed hypertension in the offspring: roles of nitric oxide and arachidonic acid metabolites. Journal of Pineal Research 57:1, pages 80-89.
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David Bishop-BaileyScott ThomsonAra AskariAshton FaulknerCaroline Wheeler-Jones. (2014) Lipid-Metabolizing CYPs in the Regulation and Dysregulation of Metabolism. Annual Review of Nutrition 34:1, pages 261-279.
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Issa E.A. Amara, Osama H. Elshenawy, Mohamed Abdelrady & Ayman O.S. El-Kadi. (2014) Acute mercury toxicity modulates cytochrome P450, soluble epoxide hydrolase and their associated arachidonic acid metabolites in C57Bl/6 mouse heart. Toxicology Letters 226:1, pages 53-62.
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Ahmed A. El-Sherbeni & Ayman O.S. El-Kadi. (2014) Alterations in cytochrome P450-derived arachidonic acid metabolism during pressure overload-induced cardiac hypertrophy. Biochemical Pharmacology 87:3, pages 456-466.
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Todd R. Harris & Bruce D. Hammock. (2013) Soluble epoxide hydrolase: Gene structure, expression and deletion. Gene 526:2, pages 61-74.
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Hassan N Althurwi, Mandy MY Tse, Ghada Abdelhamid, Beshay NM Zordoky, Bruce D Hammock & Ayman OS El‐Kadi. (2013) Soluble epoxide hydrolase inhibitor, TUPS , protects against isoprenaline‐induced cardiac hypertrophy . British Journal of Pharmacology 168:8, pages 1794-1807.
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Osama H. Elshenawy, Anwar Anwar-Mohamed, Ghada Abdelhamid & Ayman O.S. El-Kadi. (2013) Murine atrial HL-1 cell line is a reliable model to study drug metabolizing enzymes in the heart. Vascular Pharmacology 58:4, pages 326-333.
Crossref
Abdulaziz M. S. Alsaad, Beshay N. M. Zordoky, Ahmed A. El-Sherbeni & Ayman O. S. El-Kadi. (2012) Chronic Doxorubicin Cardiotoxicity Modulates Cardiac Cytochrome P450-Mediated Arachidonic Acid Metabolism in Rats. Drug Metabolism and Disposition 40:11, pages 2126-2135.
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