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Xenobiotica
the fate of foreign compounds in biological systems
Volume 43, 2013 - Issue 2
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Pharmacogenetics

Effects of clopidogrel and clarithromycin on the disposition of sibutramine and its active metabolites M1 and M2 in relation to CYP2B6*6 polymorphism

Wei Pan
,
Soo-Kyung Bae
,
Eon-Jeong Shim
,
Sung-Eun ParkDepartment of Pharmacology and PharmacoGenomics Research Center, Inje University College of Medicine, Busan, South Korea
,
Sang-Seop LeeDepartment of Pharmacology and PharmacoGenomics Research Center, Inje University College of Medicine, Busan, South Korea
,
Soo-Jin Park
,
Chang-Woo Yeo
,
Hong-Hao ZhouPharmacogenetics Research Institute, Institute of Clinical Pharmacology, Xiang-Ya School of Medicine, Central South University, Changsha, China
,
Ji-Hong Shon
&
Jae-Gook Shin
 show all
Pages 211-218 | Received 15 Apr 2012, Accepted 22 Jun 2012, Published online: 25 Jul 2012

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Zhi-Yu Wang, Meng Chen, Ling-Ling Zhu, Lu-Shan Yu, Su Zeng, Mei-Xiang Xiang & Quan Zhou. (2015) Pharmacokinetic drug interactions with clopidogrel: updated review and risk management in combination therapy. Therapeutics and Clinical Risk Management 11, pages 449-467.
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Dhananjay D. Shinde, Min-Jung Kim, Eun-Sook Jeong, Yang-Weon Kim, Ji-Woo Lee, Jae-Gook Shin & Dong-Hyun Kim. (2014) Enantioselective N-Demethylation and Hydroxylation of Sibutramine in Human Liver Microsomes and Recombinant Cytochrome P-450 Isoforms. Journal of Toxicology and Environmental Health, Part A 77:22-24, pages 1419-1430.
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Articles from other publishers (3)

Yuanyuan Wang, Muh Akbar Bahar, Anouk M E Jansen, Janwillem W H Kocks, Jan-Willem C Alffenaar, Eelko Hak, Bob Wilffert & Sander D Borgsteede. (2019) Improving antibacterial prescribing safety in the management of COPD exacerbations: systematic review of observational and clinical studies on potential drug interactions associated with frequently prescribed antibacterials among COPD patients. Journal of Antimicrobial Chemotherapy 74:10, pages 2848-2864.
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Radim Vrzal, Barbora Knoppová, Petr Bachleda & Zdeněk Dvořák. (2013) Effects of Oral Anorexiant Sibutramine on the Expression of Cytochromes P450s in Human Hepatocytes and Cancer Cell Lines. Journal of Biochemical and Molecular Toxicology 27:12, pages 515-521.
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Soo Hyeon Bae, Min Jo Kwon, Eu Jin Choi, Yu Fen Zheng, Kee Dong Yoon, Kwang-Hyeon Liu & Soo Kyung Bae. (2013) Potent inhibition of cytochrome P450 2B6 by sibutramine in human liver microsomes. Chemico-Biological Interactions 205:1, pages 11-19.
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