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Xenobiotica
the fate of foreign compounds in biological systems
Volume 43, 2013 - Issue 4
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General Xenobiochemistry

Role of carbonyl reducing enzymes in the phase I biotransformation of the non-steroidal anti-inflammatory drug nabumetone in vitro

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Pages 346-354 | Received 03 Jul 2012, Accepted 07 Aug 2012, Published online: 28 Sep 2012

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Kaori Matsumoto, Tetsuya Hasegawa, Kosuke Ohara, Chihiro Takei, Tomoyo Kamei, Junichi Koyanagi, Tamiko Takahashi & Masayuki Akimoto. (2020) A metabolic pathway for the prodrug nabumetone to the pharmacologically active metabolite, 6-methoxy-2-naphthylacetic acid (6-MNA) by non-cytochrome P450 enzymes. Xenobiotica 50:7, pages 783-792.
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Iva Boušová, Lenka Skálová, Pavel Souček & Petra Matoušková. (2015) The modulation of carbonyl reductase 1 by polyphenols. Drug Metabolism Reviews 47:4, pages 520-533.
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Petra Malátková & Vladimír Wsól. (2014) Carbonyl reduction pathways in drug metabolism. Drug Metabolism Reviews 46:1, pages 96-123.
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