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Xenobiotica
the fate of foreign compounds in biological systems
Volume 44, 2014 - Issue 7
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Research Article

Pharmacokinetics of chlorogenic acid and corydaline in DA-9701, a new botanical gastroprokinetic agent, in rats

Ji Won JungCollege of Pharmacy and Integrated Research Institute of Pharmaceutical Sciences, The Catholic University of Korea BucheonSouth Korea
,
Ju Myung KimCollege of Pharmacy and Integrated Research Institute of Pharmaceutical Sciences, The Catholic University of Korea BucheonSouth Korea
,
Jin Seok JeongResearch Center, Dong-A Pharmaceutical Co. YonginSouth Korea
,
Miwon SonResearch Center, Dong-A Pharmaceutical Co. YonginSouth Korea
,
Hye Suk LeeCollege of Pharmacy and Integrated Research Institute of Pharmaceutical Sciences, The Catholic University of Korea BucheonSouth Korea
,
Myung Gull LeeCollege of Pharmacy and Integrated Research Institute of Pharmaceutical Sciences, The Catholic University of Korea BucheonSouth Korea
&
Hee Eun KangCollege of Pharmacy and Integrated Research Institute of Pharmaceutical Sciences, The Catholic University of Korea BucheonSouth KoreaCorrespondence[email protected]
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Pages 635-643 | Received 23 Oct 2013, Accepted 09 Dec 2013, Published online: 13 Jan 2014

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Gaurav Kumar, Pankaj Paliwal, Sumedha Mukherjee, Nishant Patnaik, Sairam Krishnamurthy & Ranjana Patnaik. (2019) Pharmacokinetics and brain penetration study of chlorogenic acid in rats. Xenobiotica 49:3, pages 339-345.
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Liwei Chai, Paul Owusu Donkor, Kun Wang, Yingjie Sun, Mahmood Brobbey Oppong, Kai Wang, Liqin Ding & Feng Qiu. (2019) Metabolic profiles of corydaline in rats by ultra-performance liquid chromatography coupled to quadrupole time-of-flight mass spectrometry. Xenobiotica 49:1, pages 80-89.
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Ji Won Jung, Mi Ran Choi, Yong Sam Kwon, Jin Seok Jeong, Miwon Son & Hee Eun Kang. (2015) Gender differences in corydaline pharmacokinetics in rats. Xenobiotica 45:5, pages 456-463.
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Articles from other publishers (14)

Sascha Behne, Heike Franke, Steffen Schwarz & Dirk W. Lachenmeier. (2023) Risk Assessment of Chlorogenic and Isochlorogenic Acids in Coffee By-Products. Molecules 28:14, pages 5540.
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Kleyton Santos Veras, Flávia Nathiely Silveira Fachel, Bibiana Verlindo de Araújo, Helder Ferreira Teixeira & Letícia Scherer Koester. (2022) Oral Pharmacokinetics of Hydroxycinnamic Acids: An Updated Review. Pharmaceutics 14:12, pages 2663.
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Kleyton Santos Veras, Flávia Nathiely Silveira Fachel, Valquiria Linck Bassani, Helder Ferreira Teixeira & Letícia Scherer Koester. (2022) Cyclodextrin-Based Delivery Systems and Hydroxycinnamic Acids: Interactions and Effects on Crucial Parameters Influencing Oral Bioavailability—A Review. Pharmaceutics 14:11, pages 2530.
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Francesca Truzzi, Camilla Tibaldi, Yanxin Zhang, Giovanni Dinelli & Eros D′Amen. (2021) An Overview on Dietary Polyphenols and Their Biopharmaceutical Classification System (BCS). International Journal of Molecular Sciences 22:11, pages 5514.
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Chengyuan Liang, Nan Hui, Yuzhi Liu, Guaiping Qiao, Juan Li, Lei Tian, Xingke Ju, Minyi Jia, Hong Liu, Wenqiang Cao, Pengcheng Yu, Han Li & Xiaodong Ren. (2021) Insights into forsythia honeysuckle (Lianhuaqingwen) capsules: A Chinese herbal medicine repurposed for COVID-19 pandemic. Phytomedicine Plus 1:2, pages 100027.
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Ji‐Hyun Choi, Jee‐Young Lee, Jin Whan Cho, Seong‐Beom Koh, Young Soon Yang, Dalla Yoo, Cheol‐Min Shin & Hee Tae Kim. (2020) Double‐Blind , Randomized, Placebo‐Controlled Trial of DA ‐9701 in Parkinson's Disease: PASS ‐ GI Study . Movement Disorders 35:11, pages 1966-1976.
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Yong Sung Kim, Jung-Wook Kim, Na-Yeon Ha, Jinsung Kim & Han Seung Ryu. (2020) Herbal Therapies in Functional Gastrointestinal Disorders: A Narrative Review and Clinical Implication. Frontiers in Psychiatry 11.
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Lin Li, Congping Su, Xiangyang Chen, Qing Wang, Wenchao Jiao, Hui Luo, Jiayang Tang, Wei Wang, Sen Li & Shuzhen Guo. (2020) Chlorogenic Acids in Cardiovascular Disease: A Review of Dietary Consumption, Pharmacology, and Pharmacokinetics. Journal of Agricultural and Food Chemistry 68:24, pages 6464-6484.
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Luiz J Lacerda-Neto, Andreza GR Barbosa, Lucindo J Quintans-Junior, Henrique DM Coutinho & Francisco AB da Cunha. (2019) The complex pharmacology of natural products. Future Medicinal Chemistry 11:8, pages 797-799.
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Mirim Jin & Miwon Son. (2018) DA-9701 (Motilitone): A Multi-Targeting Botanical Drug for the Treatment of Functional Dyspepsia. International Journal of Molecular Sciences 19:12, pages 4035.
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Won-Gu Choi, Ju-Hyun Kim, Dong Kim, Yongnam Lee, Ji Yoo, Dae Shin & Hye Lee. (2018) Simultaneous Determination of Chlorogenic Acid Isomers and Metabolites in Rat Plasma Using LC-MS/MS and Its Application to A Pharmacokinetic Study Following Oral Administration of Stauntonia Hexaphylla Leaf Extract (YRA-1909) to Rats. Pharmaceutics 10:3, pages 143.
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Li Chen, Chang-shun Liu, Qing-zhen Chen, Sen Wang, Yong-ai Xiong, Jing Jing & Jia-jia Lv. (2017) Characterization, pharmacokinetics and tissue distribution of chlorogenic acid-loaded self-microemulsifying drug delivery system. European Journal of Pharmaceutical Sciences 100, pages 102-108.
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Sang Pyo Lee, Oh Young Lee, Kang Nyeong Lee, Hang Lak Lee, Ho Soon Choi, Byung Chul Yoon & Dae Won Jun. (2017) Effect of DA-9701, a Novel Prokinetic Agent, on Post-operative Ileus in Rats. Journal of Neurogastroenterology and Motility 23:1, pages 109-116.
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Ji Won Jung, Yong Sam KwonJin Seok JeongMiwon SonHee Eun Kang. (2015) Pharmacokinetics and Brain Distribution of Tetrahydropalmatine and Tetrahydroberberine after Oral Administration of DA-9701, a New Botanical Gastroprokinetic Agent, in Rats. Biological & Pharmaceutical Bulletin Biological and Pharmaceutical Bulletin 38:2, pages 285-291.
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