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Xenobiotica
the fate of foreign compounds in biological systems
Volume 44, 2014 - Issue 8
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Research Article

Investigation on pharmacokinetics, tissue distribution and excretion of a novel platinum anticancer agent in rats by Inductively Coupled Plasma Mass Spectrometry (ICP-MS)

Jie ZhaoCenter of Drug Metabolism and Pharmacokinetics, China Pharmaceutical University Nanjing, JiangsuPeople’s Republic of China
,
Yanli WenCenter of Drug Metabolism and Pharmacokinetics, China Pharmaceutical University Nanjing, JiangsuPeople’s Republic of China
,
Wei ZhangCenter of Drug Metabolism and Pharmacokinetics, China Pharmaceutical University Nanjing, JiangsuPeople’s Republic of China
,
Di ZhaoCenter of Drug Metabolism and Pharmacokinetics, China Pharmaceutical University Nanjing, JiangsuPeople’s Republic of China
,
Ali FanCenter of Drug Metabolism and Pharmacokinetics, China Pharmaceutical University Nanjing, JiangsuPeople’s Republic of China
,
Yongjie ZhangCenter of Drug Metabolism and Pharmacokinetics, China Pharmaceutical University Nanjing, JiangsuPeople’s Republic of China
,
Shuhua DengCenter of Drug Metabolism and Pharmacokinetics, China Pharmaceutical University Nanjing, JiangsuPeople’s Republic of China
,
Xin WangCenter of Drug Metabolism and Pharmacokinetics, China Pharmaceutical University Nanjing, JiangsuPeople’s Republic of China
,
Qingwang LiuCenter of Drug Metabolism and Pharmacokinetics, China Pharmaceutical University Nanjing, JiangsuPeople’s Republic of China
,
Yang LuCenter of Drug Metabolism and Pharmacokinetics, China Pharmaceutical University Nanjing, JiangsuPeople’s Republic of China
,
Zhimei WangPharmaceutical Research Center and School of Chemistry and Chemical Engineering, Southeast University Nanjing, JiangsuPeople’s Republic of China;Jiangsu Province Hi-Tech Key Laboratory for Bio-medical Research, Southeast University Nanjing, JiangsuPeople’s Republic of China
,
Shaohua GouPharmaceutical Research Center and School of Chemistry and Chemical Engineering, Southeast University Nanjing, JiangsuPeople’s Republic of China;Jiangsu Province Hi-Tech Key Laboratory for Bio-medical Research, Southeast University Nanjing, JiangsuPeople’s Republic of ChinaCorrespondence[email protected]
[email protected]
&
Xijing ChenCenter of Drug Metabolism and Pharmacokinetics, China Pharmaceutical University Nanjing, JiangsuPeople’s Republic of ChinaCorrespondence[email protected]
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Pages 757-762 | Received 28 Dec 2013, Accepted 27 Jan 2014, Published online: 14 Feb 2014

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Bhupesh S. Bhatt, Divyang H. Gandhi, Foram U. Vaidya, Chandramani Pathak & Tushar N. Patel. (2021) Cell apoptosis induced by ciprofloxacin based Cu(II) complexes: cytotoxicity, SOD mimic and antibacterial studies. Journal of Biomolecular Structure and Dynamics 39:12, pages 4555-4562.
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Donglin He, Shuhui Yin, Fuguo Han, Jingjie Zhu, Yun Shi, Zhiyuan Tong & Qingfei Liu. (2016) Pharmacokinetics and tissue distribution of two novel isomerism anticancer platinum compounds. Drug Development and Industrial Pharmacy 42:11, pages 1792-1799.
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Articles from other publishers (9)

Yongjie Zhang, Jie Xu, Jie Zhao, Huili Chen, Ning Li, Xijing Chen & Di Zhao. (2023) Preclinical pharmacokinetics, biodistribution, excretion, and plasma protein binding study of 58Fe-labeled hemin by ICP-MS. Journal of Trace Elements in Medicine and Biology 75, pages 127096.
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Divyang H. Gandhi, Foram U. Vaidya, Chandramani Pathak, Tushar N. Patel & Bhupesh S. Bhatt. (2021) Mechanistic insight of cell anti-proliferative activity of fluoroquinolone drug-based Cu(II) complexes. Molecular Diversity 26:2, pages 869-878.
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Nikola V. Nedeljković, Miloš V. Nikolić, Marina Ž. Mijajlović, Gordana P. Radić & Ana S. Stanković. (2021) Interaction of bioessential metal ions with quinolone antibiotics: Structural features and biological evaluation. Inorganica Chimica Acta 527, pages 120585.
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Martin Vojtek, Salomé Gonçalves-Monteiro, Edgar Pinto, Sára Kalivodová, Agostinho Almeida, Maria P. M. Marques, Ana L. M. Batista de Carvalho, Clara B. Martins, Helder Mota-Filipe, Isabel M. P. L. V. O. Ferreira & Carmen Diniz. (2021) Preclinical Pharmacokinetics and Biodistribution of Anticancer Dinuclear Palladium(II)-Spermine Complex (Pd2Spm) in Mice. Pharmaceuticals 14:2, pages 173.
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Reena R. Varma, Juhee G. Pandya, Foram U. Vaidya, Chandramani Pathak, Bhupesh S. Bhatt & Mohan N. Patel. (2020) Biological activities of pyrazoline-indole based Re(I) carbonyls: DNA interaction, antibacterial, anticancer, ROS production, lipid peroxidation, in vivo and in vitro cytotoxicity studies. Chemico-Biological Interactions 330, pages 109231.
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Nikolay D. Solovyev, Elena I. Fedoros, Evgenii J. Drobyshev, Natalya B. Ivanenko, Sergey E. Pigarev, Margarita L. Tyndyk, Vladimir N. Anisimov, Yury A. Vilpan & Andrey V. Panchenko. (2017) Anticancer activity and tissue distribution of platinum (II) complex with lignin-derived polymer of benzene-poly-carboxylic acids. Journal of Trace Elements in Medicine and Biology 43, pages 72-79.
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Juan Carlos García‐Ramos, Guadalupe Vértiz‐Serrano, Lucia Macías‐Rosales, Rodrigo Galindo‐Murillo, Yanis Toledano‐Magaña, Juan Pablo Bernal, Fernando Cortés‐Guzmán & Lena Ruiz‐Azuara. (2017) Isomeric Effect on the Pharmacokinetic Behavior of Anticancer Cu II Mixed Chelate Complexes: Experimental and Theoretical Approach . European Journal of Inorganic Chemistry 2017:12, pages 1728-1736.
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Ti Zhang, Shuang Cai, Wai Chee Forrest, Eva Mohr, Qiuhong Yang & M. Laird Forrest. (2016) Development and Validation of an Inductively Coupled Plasma Mass Spectrometry (ICP-MS) Method for Quantitative Analysis of Platinum in Plasma, Urine, and Tissues. Applied Spectroscopy 70:9, pages 1529-1536.
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Denis V. Navolotskii, Natalya B. Ivanenko, Nikolay D. Solovyev, Elena I. Fedoros & Andrey V. Panchenko. (2015) Pharmacokinetics and tissue distribution of novel platinum containing anticancer agent BP‐C1 studied in rabbits using sector field inductively coupled plasma mass spectrometry. Drug Testing and Analysis 7:9, pages 737-744.
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