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Xenobiotica
the fate of foreign compounds in biological systems
Volume 44, 2014 - Issue 12
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Research Article

The complex degradation and metabolism of quercetin in rat hepatocyte incubations

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Pages 1074-1082 | Received 21 Apr 2014, Accepted 03 Jun 2014, Published online: 24 Jun 2014

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Bin Guo, Fang Chou, Libin Huang, Feifan Yin, Jing Fang, Jian-Bo Wang & Zongchao Jia. (2022) Recent insights into oxidative metabolism of quercetin: catabolic profiles, degradation pathways, catalyzing metalloenzymes and molecular mechanisms. Critical Reviews in Food Science and Nutrition 0:0, pages 1-28.
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Sofia K. Georgiou-Siafis & Asterios S. Tsiftsoglou. (2023) The Key Role of GSH in Keeping the Redox Balance in Mammalian Cells: Mechanisms and Significance of GSH in Detoxification via Formation of Conjugates. Antioxidants 12:11, pages 1953.
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Xuemei Mu, Xike Xu, Xin Guo, Peiming Yang, Jiang Du, Nan Mi, Taofang Cheng, Lu Lu, Xiaopo Qi, Xinyu Wang, Jing Ning, Weidong Zhang & Ji Ye. (2019) Identification and characterization of chemical constituents in Dengzhan Shengmai Capsule and their metabolites in rat plasma by ultra-performance liquid chromatography coupled with quadrupole time-of-flight mass spectrometry. Journal of Chromatography B 1108, pages 54-64.
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Veronika Pilařová, Kateřina Plachká, Lucia Chrenková, Iveta Najmanová, Přemysl Mladěnka, František Švec, Ondřej Novák & Lucie Nováková. (2018) Simultaneous determination of quercetin and its metabolites in rat plasma by using ultra-high performance liquid chromatography tandem mass spectrometry. Talanta 185, pages 71-79.
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A. MONORI-KISS, F. KISS, J. M. RESTIFO, E. MONOS & G. L. NADASY. (2017) Chronic Administration of Quercetin Induces Biomechanical and Pharmacological Remodeling in the Rat Coronary Arteries. Physiological Research, pages 591-599.
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Zoey Harris, Micah G. Donovan, Gisele Morais Branco, Kirsten H. Limesand & Randy Burd. (2016) Quercetin as an Emerging Anti-Melanoma Agent: A Four-Focus Area Therapeutic Development Strategy. Frontiers in Nutrition 3.
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Chuan Li, Wei-Jian Zhang, Jaewoo Choi & Balz Frei. (2016) Quercetin affects glutathione levels and redox ratio in human aortic endothelial cells not through oxidation but formation and cellular export of quercetin-glutathione conjugates and upregulation of glutamate-cysteine ligase. Redox Biology 9, pages 220-228.
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Yasushi Yamazoe & Kunitoshi Mitsumori. 2016. Thresholds of Genotoxic Carcinogens. Thresholds of Genotoxic Carcinogens 171 192 .

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