Citations (23)
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Shogo Matsumoto, Shotaro Uehara, Hidetaka Kamimura, Hiroshi Ikeda, Satoshi Maeda, Machiko Hattori, Megumi Nishiwaki, Kazuhiko Kato & Hiroshi Yamazaki. (2021) Human total clearance values and volumes of distribution of typical human cytochrome P450 2C9/19 substrates predicted by single-species allometric scaling using pharmacokinetic data sets from common marmosets genotyped for P450 2C19. Xenobiotica 51:4, pages 479-493.
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Akiko Toda, Shotaro Uehara, Takashi Inoue, Masahiro Utoh, Takashi Kusama, Makiko Shimizu, Yasuhiro Uno, Masayuki Mogi, Erika Sasaki & Hiroshi Yamazaki. (2018) Effects of aging and rifampicin pretreatment on the pharmacokinetics of human cytochrome P450 probes caffeine, warfarin, omeprazole, metoprolol and midazolam in common marmosets genotyped for cytochrome P450 2C19. Xenobiotica 48:7, pages 720-726.
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Masahiro Utoh, Takashi Kusama, Tomonori Miura, Marina Mitsui, Mirai Kawano, Takahiro Hirano, Makiko Shimizu, Yasuhiro Uno & Hiroshi Yamazaki. (2018) R-warfarin clearances from plasma associated with polymorphic cytochrome P450 2C19 and simulated by individual physiologically based pharmacokinetic models for 11 cynomolgus monkeys. Xenobiotica 48:2, pages 206-210.
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Zuzana E. Haarhoff, Melissa A. Kramer, Tatyana A. Zvyaga, Jun Zhang, Priyadeep Bhutani, Murali Subramanian & A. David Rodrigues. (2017) Comprehensive evaluation of liver microsomal cytochrome P450 3A (CYP3A) inhibition: comparison of cynomolgus monkey and human. Xenobiotica 47:6, pages 470-478.
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Masahiro Utoh, Hiroshi Suemizu, Marina Mitsui, Mirai Kawano, Akiko Toda, Shotaro Uehara, Yasuhiro Uno, Makiko Shimizu, Erika Sasaki & Hiroshi Yamazaki. (2016) Human plasma concentrations of cytochrome P450 probe cocktails extrapolated from pharmacokinetics in mice transplanted with human hepatocytes and from pharmacokinetics in common marmosets using physiologically based pharmacokinetic modeling. Xenobiotica 46:12, pages 1049-1055.
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Satomi Shida & Hiroshi Yamazaki. (2016) Human plasma concentrations of five cytochrome P450 probes extrapolated from pharmacokinetics in dogs and minipigs using physiologically based pharmacokinetic modeling. Xenobiotica 46:9, pages 759-764.
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Shotaro Uehara, Yasuhiro Uno, Takashi Inoue, Takako Suzuki, Masahiro Utoh, Erika Sasaki & Hiroshi Yamazaki. (2016) Caffeine 7-N-demethylation and C-8-oxidation mediated by liver microsomal cytochrome P450 enzymes in common marmosets. Xenobiotica 46:7, pages 573-578.
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Shotaro Uehara, Takashi Inoue, Masahiro Utoh, Akiko Toda, Makiko Shimizu, Yasuhiro Uno, Erika Sasaki & Hiroshi Yamazaki. (2016) Simultaneous pharmacokinetics evaluation of human cytochrome P450 probes, caffeine, warfarin, omeprazole, metoprolol and midazolam, in common marmosets (Callithrix jacchus). Xenobiotica 46:2, pages 163-168.
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Arduino A Mangoni & Alberto Pilotto. (2016) New drugs and patient-centred end-points in old age: setting the wheels in motion. Expert Review of Clinical Pharmacology 9:1, pages 81-89.
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Satomi Shida, Masahiro Utoh, Norie Murayama, Makiko Shimizu, Yasuhiro Uno & Hiroshi Yamazaki. (2015) Human plasma concentrations of cytochrome P450 probes extrapolated from pharmacokinetics in cynomolgus monkeys using physiologically based pharmacokinetic modeling. Xenobiotica 45:10, pages 881-886.
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Articles from other publishers (13)
Eva Sanchez-Quant, Maria Lucia Richter, Maria Colomé-Tatché & Celia Pilar Martinez-Jimenez. (2023) Single-cell metabolic profiling reveals subgroups of primary human hepatocytes with heterogeneous responses to drug challenge. Genome Biology 24:1.
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Xiantang Li, Rosemary Santos, Jan E. Bernal, Dingzhou D. Li, Maureen Hargaden & Nasir K. Khan. (2022)
Biology and postnatal development of organ systems of cynomolgus monkeys (
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Hiroshi Yamazaki & Makiko Shimizu. (2023) Species Specificity and Selection of Models for Drug Oxidations Mediated by Polymorphic Human Enzymes. Drug Metabolism and Disposition 51:1, pages 123-129.
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Yasuhiro Uno, Shotaro Uehara & Hiroshi Yamazaki. 2022. Pharmacology and Toxicology of Cytochrome P450 – 60th Anniversary. Pharmacology and Toxicology of Cytochrome P450 – 60th Anniversary
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Noelia Morales-Prieto, Nieves López de Lerma, Isabel L. Pacheco, Paula V. Huertas-Abril, José Pérez, Rafael Peinado & Nieves Abril. (2020) Protective effect of Pedro-Ximénez must against p,p'-DDE-induced liver damages in aged Mus spretus mice. Food and Chemical Toxicology 136, pages 110984.
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Yasuhiro Uno, Shotaro Uehara & Hiroshi Yamazaki. (2018) Genetic polymorphisms of drug-metabolizing cytochrome P450 enzymes in cynomolgus and rhesus monkeys and common marmosets in preclinical studies for humans. Biochemical Pharmacology 153, pages 184-195.
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Hiroshi Yamazaki. (2016) Differences in Toxicological and Pharmacological Responses Mediated by Polymorphic Cytochromes P450 and Related Drug-Metabolizing Enzymes. Chemical Research in Toxicology 30:1, pages 53-60.
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H. Yamazaki. 2017. Comprehensive Medicinal Chemistry III. Comprehensive Medicinal Chemistry III
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Yasuhiro Uno, Shotaro Uehara & Hiroshi Yamazaki. (2016) Utility of non-human primates in drug development: Comparison of non-human primate and human drug-metabolizing cytochrome P450 enzymes. Biochemical Pharmacology 121, pages 1-7.
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Lei Chen, Yu-Hang Zhang, Quan Zou, Chen Chu & Zhiliang Ji. (2016) Analysis of the chemical toxicity effects using the enrichment of Gene Ontology terms and KEGG pathways. Biochimica et Biophysica Acta (BBA) - General Subjects 1860:11, pages 2619-2626.
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S. Uehara, Y. Uno, T. Inoue, M. Kawano, M. Shimizu, A. Toda, M. Utoh, E. Sasaki & H. Yamazaki. (2016) Individual Differences in Metabolic Clearance of S-Warfarin Efficiently Mediated by Polymorphic Marmoset Cytochrome P450 2C19 in Livers. Drug Metabolism and Disposition 44:7, pages 911-915.
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Masahiro Utoh, Takahiro Yoshikawa, Yoshiharu Hayashi, Makiko Shimizu, Kazuhide Iwasaki, Yasuhiro Uno & Hiroshi Yamazaki. (2015) Slow R-warfarin 7-hydroxylation mediated by P450 2C19 genetic variants in cynomolgus monkeys in vivo. Biochemical Pharmacology 95:2, pages 110-114.
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Shinya Hosaka, Norie Murayama, Masahiro Satsukawa, Makiko Shimizu, Shotaro Uehara, Hideki Fujino, Kazuhide Iwasaki, Shunsuke Iwano, Yasuhiro Uno & Hiroshi Yamazaki. (2015) Evaluation of 89 Compounds for Identification of Substrates for Cynomolgus Monkey CYP2C76, a New Bupropion/Nifedipine Oxidase. Drug Metabolism and Disposition 43:1, pages 27-33.
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