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Xenobiotica
the fate of foreign compounds in biological systems
Volume 46, 2016 - Issue 2
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Xenobiotic transporters

Interaction of six protoberberine alkaloids with human organic cation transporters 1, 2 and 3

Liping LiLaboratory of Pharmaceutical Analysis and Drug Metabolism, Zhejiang Province Key Laboratory of Anti-Cancer Drug Research, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, Zhejiang, P.R. China
,
Siyuan SunLaboratory of Pharmaceutical Analysis and Drug Metabolism, Zhejiang Province Key Laboratory of Anti-Cancer Drug Research, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, Zhejiang, P.R. China
,
Yayun WengLaboratory of Pharmaceutical Analysis and Drug Metabolism, Zhejiang Province Key Laboratory of Anti-Cancer Drug Research, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, Zhejiang, P.R. China
,
Feifeng SongLaboratory of Pharmaceutical Analysis and Drug Metabolism, Zhejiang Province Key Laboratory of Anti-Cancer Drug Research, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, Zhejiang, P.R. China
,
Sisi ZhouLaboratory of Pharmaceutical Analysis and Drug Metabolism, Zhejiang Province Key Laboratory of Anti-Cancer Drug Research, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, Zhejiang, P.R. China
,
Mengru BaiLaboratory of Pharmaceutical Analysis and Drug Metabolism, Zhejiang Province Key Laboratory of Anti-Cancer Drug Research, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, Zhejiang, P.R. China
,
Hui ZhouLaboratory of Pharmaceutical Analysis and Drug Metabolism, Zhejiang Province Key Laboratory of Anti-Cancer Drug Research, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, Zhejiang, P.R. China
,
Su ZengLaboratory of Pharmaceutical Analysis and Drug Metabolism, Zhejiang Province Key Laboratory of Anti-Cancer Drug Research, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, Zhejiang, P.R. China
&
Huidi JiangLaboratory of Pharmaceutical Analysis and Drug Metabolism, Zhejiang Province Key Laboratory of Anti-Cancer Drug Research, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, Zhejiang, P.R. ChinaCorrespondence[email protected]
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Pages 175-183 | Received 08 Apr 2015, Accepted 26 May 2015, Published online: 02 Jul 2015

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Siyuan Sun, Sisi Zhou, Shaowei Lei, Shujie Zhu, Kai Wang, Huidi Jiang & Hui Zhou. (2019) Jatrorrhizine reduces 5-HT and NE uptake via inhibition of uptake-2 transporters and produces antidepressant-like action in mice. Xenobiotica 49:10, pages 1237-1243.
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Ning Chen, Xiao-yan Yang, Chang-e Guo, Xin-ning Bi, Jian-hua Chen, Hong-ying Chen, Hong-pin Li, Hong-ying Lin & Yu-jie Zhang. (2018) The oral bioavailability, excretion and cytochrome P450 inhibition properties of epiberberine: an in vivo and in vitro evaluation. Drug Design, Development and Therapy 12, pages 57-65.
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Lucie Hyrsova, Tomas Smutny, Frantisek Trejtnar & Petr Pavek. (2016) Expression of organic cation transporter 1 (OCT1): unique patterns of indirect regulation by nuclear receptors and hepatospecific gene regulation. Drug Metabolism Reviews 48:2, pages 139-158.
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Anne T. Nies, Elke Schaeffeler & Matthias Schwab. (2022) Hepatic solute carrier transporters and drug therapy: Regulation of expression and impact of genetic variation. Pharmacology & Therapeutics 238, pages 108268.
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Muhammad Asyraf Abduraman, Nor Hidayah Mustafa, Nik Soriani Yaacob, Azimah Amanah & Mei Lan Tan. (2022) Cytochrome P450 inhibition activities of non-standardized botanical products. Journal of Ethnopharmacology 296, pages 115406.
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Cheng-Huang Shen, Jin-Yi Wu, Shou-Chieh Wang, Chi-Hung Wang, Chen-Tai Hong, Pei-Yu Liu, Sin-Rong Wu & Yi-Wen Liu. (2022) The suppressive role of phytochemical-induced glutathione S-transferase Mu 2 in human urothelial carcinoma cells. Biomedicine & Pharmacotherapy 151, pages 113102.
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Furong Zhong, Yang Chen, Jia Chen, Hailang Liao, Yirou Li & Yuntong Ma. (2022) Jatrorrhizine: A Review of Sources, Pharmacology, Pharmacokinetics and Toxicity. Frontiers in Pharmacology 12.
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Karima Alim, Amélie Moreau, Arnaud Bruyère, Elodie Jouan, Claire Denizot, Anne T. Nies, Yannick Parmentier & Olivier Fardel. (2021) Inhibition of organic cation transporter 3 activity by tyrosine kinase inhibitors. Fundamental & Clinical Pharmacology 35:5, pages 919-929.
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Bastian Haberkorn, Martin F. Fromm & Jörg König. (2021) Transport of Drugs and Endogenous Compounds Mediated by Human OCT1: Studies in Single- and Double-Transfected Cell Models. Frontiers in Pharmacology 12.
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Shiwei Zhou, Sujuan Zeng & Yan Shu. (2021) Drug-Drug Interactions at Organic Cation Transporter 1. Frontiers in Pharmacology 12.
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Maria D. Auxtero, Susana Chalante, Mário R. Abade, Rui Jorge & Ana I. Fernandes. (2021) Potential Herb–Drug Interactions in the Management of Age-Related Cognitive Dysfunction. Pharmaceutics 13:1, pages 124.
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Linqiu Liu, Junjun Li & Yang He. (2020) Multifunctional epiberberine mediates multi-therapeutic effects. Fitoterapia 147, pages 104771.
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T.P. Sri Laasya, Shikha Thakur, Ramarao Poduri & Gaurav Joshi. (2020) Current insights toward kidney injury: Decrypting the dual role and mechanism involved of herbal drugs in inducing kidney injury and its treatment. Current Research in Biotechnology 2, pages 161-175.
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Yingchun Chen, Cui Li, Yaodong Yi, Weijuan Du, Huidi Jiang, Su Zeng & Hui Zhou. (2020) Organic Cation Transporter 1 and 3 Contribute to the High Accumulation of Dehydrocorydaline in the Heart. Drug Metabolism and Disposition 48:10, pages 1074-1083.
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Peter Yaro, Jing Nie, Mingcheng Xu, Kui Zeng & Su Zeng. (2020) Development and Validation of Liquid Chromatography-mass Spectrometry Method for the Determination of Intracellular Concentration of Ginkgolide A, B, C, and Bilobalide in Transporter-Expressing Cells. Current Pharmaceutical Analysis 16:6, pages 763-773.
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Cui Li, Liping Li, Yaodong Yi, Wei Wang, Jingqun Yuan, Fuqing Tan, Danbo Fang, Su Zeng, Hui Zhou & Huidi Jiang. (2020) L-tetrahydropalmatine attenuates cisplatin-induced nephrotoxicity via selective inhibition of organic cation transporter 2 without impairing its antitumor efficacy. Biochemical Pharmacology 177, pages 114021.
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Lisha Jin, Sisi Zhou, Shujie Zhu, Shaowei Lei, Weijuan Du, Huidi Jiang, Su Zeng & Hui Zhou. (2019) Dehydrocorydaline induced antidepressant-like effect in a chronic unpredictable mild stress mouse model via inhibiting uptake-2 monoamine transporters. European Journal of Pharmacology 864, pages 172725.
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Jiaying Long, Jiawen Song, Li Zhong, Yanmei Liao, Luona Liu & Xiaofang Li. (2019) Palmatine: A review of its pharmacology, toxicity and pharmacokinetics. Biochimie 162, pages 176-184.
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Yan Li, Jezrael Revalde & James W. Paxton. (2017) The effects of dietary and herbal phytochemicals on drug transporters. Advanced Drug Delivery Reviews 116, pages 45-62.
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Ayman F. El‐Kattan. 2017. Oral Bioavailability Assessment. Oral Bioavailability Assessment 77 138 .
Margarida EstudanteGraça Soveral, José G. MoraisLeslie Z. Benet. (2016) Insights into solute carriers: physiological functions and implications in disease and pharmacokinetics. MedChemComm 7:8, pages 1462-1478.
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L P Li, F F Song, Y Y Weng, X Yang, K Wang, H M Lei, J Ma, H Zhou & H D Jiang. (2016) Role of OCT2 and MATE1 in renal disposition and toxicity of nitidine chloride. British Journal of Pharmacology 173:16, pages 2543-2554.
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