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Xenobiotica
the fate of foreign compounds in biological systems
Volume 46, 2016 - Issue 5
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Xenobiotic Transporters

The different metabolism of morusin in various species and its potent inhibition against UDP-glucuronosyltransferase (UGT) and cytochrome p450 (CYP450) enzymes

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Pages 467-476 | Received 10 Jul 2015, Accepted 21 Aug 2015, Published online: 15 Sep 2015

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Hua Jiang, Xiangcai Meng, Xianbao Shi & Jingming Yang. (2020) Interspecies metabolic diversity of artocarpin in vitro mammalian liver microsomes. Bioscience, Biotechnology, and Biochemistry 84:4, pages 661-669.
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Jun-Ming Chen, Yong-Mei Xia, Yan-Dong Zhang, Tong-Tong Zhang, Qing-Rui Peng & Yun Fang. (2018) Influence of substrates on the in vitro kinetics of steviol glucuronidation and interaction between steviol glycosides metabolites and UGT2B7. International Journal of Food Sciences and Nutrition 69:4, pages 472-479.
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Anita Panek-Krzyśko & Monika Stompor-Gorący. (2021) The Pro-Health Benefits of Morusin Administration—An Update Review. Nutrients 13:9, pages 3043.
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Dong Wook Choi, Sang Woo Cho, Seok-Geun Lee & Cheol Yong Choi. (2020) The Beneficial Effects of Morusin, an Isoprene Flavonoid Isolated from the Root Bark of Morus. International Journal of Molecular Sciences 21:18, pages 6541.
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Yali Liu, Mingyue Zhou, Chen Jin, Jinxiang Zeng, Chao Huang, Qiuye Song & Yonggui Song. (2020) Preparation of a Sensor Based on Biomass Porous Carbon/Covalent-Organic Frame Composites for Pesticide Residues Detection. Frontiers in Chemistry 8.
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Dan Liu, Lin Zhang, Lixin Duan, Jinjun Wu, Ming Hu, Zhongqiu Liu & Caiyan Wang. (2019) Potential of herb-drug / herb interactions between substrates and inhibitors of UGTs derived from herbal medicines. Pharmacological Research 150, pages 104510.
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Xianbao Shi, Gang Zhang, Guangbo Ge, Zhe Guo, Yonggui Song, Dan Su & Lina Shan. (2019) In Vitro Metabolism of Auriculasin and Its Inhibitory Effects on Human Cytochrome P450 and UDP-Glucuronosyltransferase Enzymes. Chemical Research in Toxicology 32:10, pages 2125-2134.
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Lina Shan, Gang Zhang, Zhe Guo & Xianbao Shi. (2019) In vitro investigation of permeability and metabolism of licoricidin. Life Sciences 234, pages 116770.
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Chuqi Hou, Wenqin Liu, Zhi Liang, Weichao Han, Jinqing Li, Ling Ye, Menghua Liu, Zheng Cai, Jie Zhao, Yi Chen, Shuwen Liu & Lan Tang. (2018) UGT-mediated metabolism plays a dominant role in the pharmacokinetic behavior and the disposition of morusin in vivo and in vitro. Journal of Pharmaceutical and Biomedical Analysis 154, pages 339-353.
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Wei Qu & Xuezheng Liu. (2018) Identification of cytochrome P450 isoforms involved in the metabolism of artocarpin and assessment of its drug-drug interaction. Biomedical Chromatography 32:4, pages e4149.
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Xianbao Shi, Brianna Mackie, Gang Zhang, Shuman Yang, Yonggui Song, Dan Su, Yali Liu & Lina Shan. (2016) Identification of the Metabolic Enzyme Involved Morusin Metabolism and Characterization of Its Metabolites by Ultraperformance Liquid Chromatography Quadrupole Time-of-Flight Mass Spectrometry (UPLC/Q-TOF-MS/MS). Evidence-Based Complementary and Alternative Medicine 2016, pages 1-10.
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