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Xenobiotica
the fate of foreign compounds in biological systems
Volume 6, 1976 - Issue 9
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Original Article

A Reappraisal of the Stereoselective Metabolism of Nicotine to Nicotine-l'-N-oxide

Bernard Testa School of Pharmacy, University of Lausanne, CH-1005, Lausanne, Switzerland
,
Peter Jenner Department of Neurology, Institute of Psychiatry and King's College Hospital Medical School, London
,
Arnold H. Beckett Department of Pharmacy, Chelsea College, University of London
&
John W. Gorrod Department of Pharmacy, Chelsea College, University of London
Pages 553-556 | Received 29 Apr 1976, Published online: 30 Sep 2009

Citations (14)

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M. Ŝktefek, L. Beneŝk, M. Jergelová, V. ŜkĉKasnár, L. Turi-nagy & P. Koĉkiŝk. (1987) Biotransformation of stobadine, a γ-carboline antiarrhythmic and cardioprotective agent, in rat liver microsomes. Xenobiotica 17:9, pages 1067-1073.
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Peter Hlavica & John W. Gorrod. (1982) Biological Oxidation of Nitrogen in Organic Compounds and Disposition of N-Oxidized Product. Critical Reviews in Biochemistry 12:1, pages 39-101.
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Articles from other publishers (12)

Mui C. Tsai & John W. Gorrod. 1999. Analytical Determination of Nicotine and Related Compounds and their Metabolites. Analytical Determination of Nicotine and Related Compounds and their Metabolites 645 668 .
Peyton JacobIIIIII & Gary D. Byrd. 1999. Analytical Determination of Nicotine and Related Compounds and their Metabolites. Analytical Determination of Nicotine and Related Compounds and their Metabolites 191 224 .
Mark R. Hadley, Harriet G. Oldham, Lyaquatali A. Damani & Andrew J. Hutt. (2004) Asymmetric metabolic N ‐oxidation of N ‐ethyl‐ N ‐methylaniline by purified flavin‐containing monooxygenase . Chirality 6:2, pages 98-104.
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M. R. Hadley, L. A. Damani, A. J. Hutt, H. G. Oldham, J. Murphy & P. Camilleri. (1993) Enantiomeric resolution ofN-alkyl-N-methylanilineN-oxides by high-performance liquid chromatography. Chromatographia 37:9-10, pages 487-491.
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Alan F. Casy & George H. DewarAlan F. Casy & George H. Dewar. 1993. The Steric Factor in Medicinal Chemistry. The Steric Factor in Medicinal Chemistry 327 365 .
David R. Webb, Vijendra KR. Singh, H. Hugh Fudenberg, Roger W. Russell, L. Öhman, G. Maluszynska, K.-E. MAgnusson, O. Stendahl, Peter A. Lambert, David H. P. Streeten, Gunnar H. AndersonJrJr, Vickram Ramkumar, George Pierson, Gary L. Stiles, Bernard Testa, Joachm M. Mayer, Duncan Stewart-Tull, Michael Williams, Gary L. Niel, Peter Hambleton, Stephen D. Prior, Andrew Robinson, Jed F. Fisher & Paul A. AristoffBernard Testa & Joachim M. Mayer. 1988. Progress in Drug Research / Fortschritte der Arzneimittelforschung / Progrès des recherches pharmaceutiques. Progress in Drug Research / Fortschritte der Arzneimittelforschung / Progrès des recherches pharmaceutiques 249 303 .
G.David McCoy, Paul C. Howard & George J. DeMarco. (1986) Characterization of hamster liver nicotine metabolism. Biochemical Pharmacology 35:16, pages 2767-2773.
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. 1984. Comprehensive Heterocyclic Chemistry. Comprehensive Heterocyclic Chemistry 673 731 .
L.A. Damani & D.E. Case. 1984. Comprehensive Heterocyclic Chemistry. Comprehensive Heterocyclic Chemistry 223 246 .
Janine Rose & Neal CastagnoliJr.Jr.. (2006) The metabolism of tertiary amines. Medicinal Research Reviews 3:1, pages 73-88.
Crossref
Trevor RobinsonTrevor Robinson. 1981. The Biochemistry of Alkaloids. The Biochemistry of Alkaloids 166 181 .
Lawrence K. Low & Neal CastagnoliJr.Jr.. 1978. 304 315 .

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