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Xenobiotica
the fate of foreign compounds in biological systems
Volume 8, 1978 - Issue 6
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Research Article

Metabolism of 3-(2′,4′,5′-Triethoxybenzoyl)propionic Acid, a New Biliary Smooth Muscle Relaxant with Choleretic Activity: I. Disposition after a Single Administration in Rats and Dogs

Shigeharu Tanayama Medicinal Research Laboratories, Central Research Division, Takeda Chemical Industries Ltd., Juso-Honmachi, Yodogawa-ku, Osaka 532, Japan
,
Takuo Kobayashi Medicinal Research Laboratories, Central Research Division, Takeda Chemical Industries Ltd., Juso-Honmachi, Yodogawa-ku, Osaka 532, Japan
&
Yoshio Kanai Medicinal Research Laboratories, Central Research Division, Takeda Chemical Industries Ltd., Juso-Honmachi, Yodogawa-ku, Osaka 532, Japan
Pages 365-375 | Received 27 May 1977, Published online: 22 Sep 2008

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Yuu Moriya, Akifumi Kogame, Yoshihiko Tagawa, Akio Morohashi, Takahiro Kondo & Satoru Asahi. (2019) Investigation of disposition for TAK-448, a synthetic peptide of kisspeptin analog, in rats and dogs using the radiolabeled TAK-448 suitable for pharmacokinetic study. Xenobiotica 49:7, pages 833-839.
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Takuo Kobayashi, Hideaki Hohnoki, Yoshio Esumi, Toshiharu Ohtsuki, Tohru Washino & Shigeharu Tanayama. (1988) Metabolism and disposition of (RS)-2-methoxy-3-(octadecylcarbamoyloxy)propyl 2-(3-thiazolio)ethyl phosphate (MOTP) in rats and dogs. Xenobiotica 18:1, pages 49-59.
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A. N. Fisher, M. G. Neale & D. A. Smith. (1981) Methods for the estimation of the excretion of proxicromil and its metabolites in the milk of nursing rat mothers. Xenobiotica 11:12, pages 871-877.
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Yoshio Kanai, Yoichi Nakai, Nobuyuki Nakajima & Shigeharu Tanayama. (1979) Metabolic Disposition of 6-Ethyl-3-(1H-tetrazol-5-yl)-chromone, a New Antiallergic Agent, in the Rat, Guinea-pig, Rabbit, Dog and Monkey. Xenobiotica 9:1, pages 33-50.
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Shigeharu Tanayama, Takuo Kobayashi & Yoshio Kanai. (1978) Metabolism of 3-(2′,4′,5′-Triethoxybenzoyl)propionic Acid, a New Biliary Smooth Muscle Relaxant with Choleretic Activity: II. Metabolism after Repeated Dosing in Rats, in Relation to Choleretic Activity. Xenobiotica 8:6, pages 377-382.
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Takuo Kobayashi, Yoshio Kanai & Shigeharu Tanayama. (1978) Human Urinary Metabolites of 3-(2′,4′,5′-Triethoxybenzoyl)propionic Acid, a New Biliary Smooth Muscle Relaxant with Choleretic Activity. Xenobiotica 8:12, pages 737-743.
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Takuo Kobayashi, Shigeharu Tanayama & Yoshio Kanai. (1978) Biotransformation of 3-(2′,4′,5′-Triethoxybenzoyl)propionic Acid, a New Biliary Smooth Muscle Relaxant with Choleretic Activity, in Rats. Xenobiotica 8:9, pages 535-545.
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Articles from other publishers (2)

Toshiyuki Takeuchi, Masami Nonaka, Sumie Yoshitomi, Tomoaki Higuchi, Takuya Ebihara, Yoshihiro Maeshiba, Masahiro Kawase & Satoru Asahi. (2008) Marked impact of P‐glycoprotein on the absorption of TAK‐427 in rats. Biopharmaceutics & Drug Disposition 29:6, pages 311-323.
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Takahiro Kondo, Kiyoshi Yoshida, Yoshinobu Yoshimura & Shigeharu Tanayama. (2006) Enantioselective pharmacokinetics in animals of pazinaclone, a new isoindoline anxiolytic, and its active metabolite. Biopharmaceutics & Drug Disposition 16:9, pages 755-773.
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