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Xenobiotica
the fate of foreign compounds in biological systems
Volume 11, 1981 - Issue 9
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Research Article

Extrahepatic sites of metabolism of N-nitrosopyrrolidine in mice and rats

E. Brittebo Department of Toxicology, University of Uppsala, Box 573, S-751 23, Uppsala, Sweden
,
B. Löfberg Department of Toxicology, University of Uppsala, Box 573, S-751 23, Uppsala, Sweden
&
H. Tjälve Department of Toxicology, University of Uppsala, Box 573, S-751 23, Uppsala, Sweden
Pages 619-625 | Received 12 May 1981, Published online: 22 Sep 2008

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Jean-Marie Heydel, Philippe Faure & Fabrice Neiers. (2019) Nasal odorant metabolism: enzymes, activity and function in olfaction. Drug Metabolism Reviews 51:2, pages 224-245.
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C. J. Reed. (1993) Drug Metabolism in the Nasal Cavity: Relevance to Toxicology. Drug Metabolism Reviews 25:1-2, pages 173-205.
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Alan R. Dahl & William M. Hadley. (1991) Nasal Cavity Enzymes Involved in Xenobiotic Metabolism: Effects on the Toxicity of Inhalants. Critical Reviews in Toxicology 21:5, pages 345-372.
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Hans Tjälve. (1991) The Tissue Distribution and the Tissue Specificity of Bioactivation of Some Tobacco-Specific and Some Other N-Nitrosamines. Critical Reviews in Toxicology 21:4, pages 265-294.
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Hans Tjälve. (1986) Tracing Tissues with N-Nitrosamine-metabolizing Capacity. Upsala Journal of Medical Sciences 91:3, pages 273-281.
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Patrick Bénard, Viviane Burgat & André G. Rico. (1985) Application of Whole-Body Autoradiography in Toxicology. CRC Critical Reviews in Toxicology 15:2, pages 181-215.
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Herman A. J. Schut & Andre Castonguay. (1984) Metabolism of Carcinogenic Amino Derivatives in Various Species and DNA Alkylation by Their Metabolites. Drug Metabolism Reviews 15:4, pages 753-839.
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Articles from other publishers (17)

Kamila Blum, Rex FitzGerald, Martin F. Wilks, Ester Lovsin Barle & Nancy B. Hopf. (2023) Use of the benchmark‐dose (BMD) approach to derive occupational exposure limits (OELs) for genotoxic carcinogens: N‐nitrosamines. Journal of Applied Toxicology 43:8, pages 1183-1200.
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Alan M. Jeffrey, Michael J. Iatropoulos & Gary M. Williams. (2016) Nasal Cytotoxic and Carcinogenic Activities of Systemically Distributed Organic Chemicals. Toxicologic Pathology 34:7, pages 827-852.
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Celia J Reed. (1997) In vitro models of nasal cavity toxicity. Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 380:1-2, pages 97-111.
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Peter H. Bach & John BakerPatrick Bénard. 1991. Histochemical and Immunohistochemical Techniques. Histochemical and Immunohistochemical Techniques 11 51 .
J. Jenn & G.H. Dodd. (1988) XENOBIOTIC METABOLISM IN THE NASAL EPITHELIUM. Drug Metabolism and Drug Interactions 6:2.
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A. R. Dahl. 1988. Inhalation Toxicology. Inhalation Toxicology 41 65 .
Alan R. Dahl. 1988. Molecular Neurobiology of the Olfactory System. Molecular Neurobiology of the Olfactory System 51 70 .
Björn Hellman & Hans Tjälve. (2009) Effects of N-Nitrosopyrrolidine and N-Nitrosoproline on the Incorporation of 3H-Thymidine into the DNA of Various Organs of the Mouse: Tissue Specificity and Effects of Ethanol Consumption. Acta Pharmacologica et Toxicologica 59:4, pages 279-284.
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Böel Löfberg & Hans Tjälve. (1986) Tracing tissues with chloroform-metabolizing capacity in rats. Toxicology 39:1, pages 13-35.
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Alan R. Dahl. 1986. Biological Reactive Intermediates III. Biological Reactive Intermediates III 367 372 .
Alan R. Dahl. (1985) Mutagenicity of some dialkylnitrosamines, cyclic nitrosamines and N,N-diethanolnitrosamine in Salmonella typhimurium with rat and rabbit nasal, lung and liver S9 homogenates. Mutation Research/Genetic Toxicology 158:3, pages 141-147.
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B. Löfberg & H. Tjälve. (1985) Tissue specificity of N-nitrosomorpholine metabolism in Sprague-Dawley rats. Food and Chemical Toxicology 23:7, pages 647-654.
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Bo?l L?fberg & Hans Tj?lve. (1985) Autoradiography of [14C]N-nitrosodiethanolamine in Sprague-Dawley rats. Cancer Letters 26:2, pages 129-137.
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E.B. Brittebo & M. ?ahlman. (1984) Nasal mucosa from rat fetuses and neonates metabolizes the nasal carcinogen phenacetin. Toxicology Letters 23:3, pages 279-285.
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Hans Tjälve & Boël Löfberg. (1983) Extrahepatic sites of metabolism of carbon tetrachloride in rats. Chemico-Biological Interactions 46:3, pages 299-316.
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Eva B. Brittebo. (2009) N‐Demethylation of Aminopyrine by the Nasal Mucosa in Mice and Rats. Acta Pharmacologica et Toxicologica 51:3, pages 227-232.
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E.B. Brittebo & H. Tjälve. (1982) Tissue-specificity of N-nitrosodibutylamine metabolism in Sprague-Dawley rats. Chemico-Biological Interactions 38:2, pages 231-242.
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