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Xenobiotica
the fate of foreign compounds in biological systems
Volume 12, 1982 - Issue 1
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Research Article

Interaction of ranitidine with liver microsomes

S. Rendić Laboratory of Chemical Pharmacology, “Podravka-Institute”, Radnička cesta 224, YU-41000, Zagreb, Yugoslavia
,
T. Alebić-Kolbah Laboratory of Chemical Pharmacology, “Podravka-Institute”, Radnička cesta 224, YU-41000, Zagreb, Yugoslavia
,
F. Kajfež Laboratory of Chemical Pharmacology, “Podravka-Institute”, Radnička cesta 224, YU-41000, Zagreb, Yugoslavia
&
H.-H. Ruf Department of Physiological Chemistry, University of the Saarland, Homburg/Saar, FR Germany
Pages 9-17 | Received 10 Jul 1981, Published online: 22 Sep 2008

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Lev M. Weiner. (1986) Magnetic Resonance Study of the Structure and Functions of Cytochrome P45. Critical Reviews in Biochemistry 20:2, pages 139-200.
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I Skånberg, K-J Hoffmann & C G Regårdh. (1986) Pharmacokinetics and Metabolism of Omeprazole in Animals. Scandinavian Journal of Gastroenterology 21:sup118, pages 92-93.
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S.-D. Lee, J.-Y. Wang, C.-H. Cho, J.-C. Wu, R.-H. Lu, K.-H. Lai, Y.-T. Tsai & K.-J. Lo. (1986) Effects of H2-Receptor Antagonists on the Rat Liver after Partial Hepatectomy or Carbon Tetrachloride-Induced Hepatic Injury. Scandinavian Journal of Gastroenterology 21:8, pages 984-990.
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S. Rendic & H.-H. Ruf. (1985) Characterization of pirenzepine interaction with cytochrome P-450. Xenobiotica 15:5, pages 399-405.
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A. Bast, K. M. Savenije-chapel & B. H. Kroes. (1984) Inhibition of mono-oxygenase and oxidase activity of rat-hepatic cytochrome P-450 by H2-receptor blockers. Xenobiotica 14:5, pages 399-408.
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Articles from other publishers (37)

Slobodan P. Rendić, Rachel D. Crouch & F. Peter Guengerich. (2022) Roles of selected non-P450 human oxidoreductase enzymes in protective and toxic effects of chemicals: review and compilation of reactions. Archives of Toxicology 96:8, pages 2145-2246.
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D Brian Jones, Michael S Ching, Denis J Morgan, Jeanette D Anderson & Richard A Smallwood. (1985) The inhibitory effects of ranitidine and Cimetidine on propranolol elimination by the rat isolated perfused liver. Journal of Pharmacy and Pharmacology 37:3, pages 196-198.
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Roshan M. Bashir & James H. Lewis. (1995) HEPATOTOXICITY OF DRUGS USED IN THE TREATMENT OF GASTROINTESTINAL DISORDERS. Gastroenterology Clinics of North America 24:4, pages 937-967.
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David S. Cooling. (1993) Theophylline toxicity. The Journal of Emergency Medicine 11:4, pages 415-425.
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H. Mönig, K. Hoffmann, E. E. Ohnhaus & H. M. Schulte. (1992) Ranitidine treatment and cortisol metabolism in man. European Journal of Drug Metabolism and Pharmacokinetics 17:1, pages 9-12.
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Greg W. Hegman & Robert P. Gilbert. (2016) Ranitidine—Theophylline Interaction—Fact or Fiction?. DICP 25:1, pages 21-25.
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Mark R. Dilloway & F. Lant. (2006) Effect of H 2 ‐receptor antagonists on the pharmacokinetics of 5‐fluorouracil in the rat and monkey . Biopharmaceutics & Drug Disposition 12:1, pages 17-28.
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C. Panella, L. Makowka, M. Barone, L. Polimeno, S. Rizzi, J. Demetris, S. Bell, F. W. Guglielmi, J. G. Prelich, D. H. Van Thiel, T. E. Starzl & A. Francavilla. (1990) Effect of ranitidine on acetaminophen-induced hepatotoxicity in dogs. Digestive Diseases and Sciences 35:3, pages 385-391.
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Dennis F. Thompson, Marsha A. Raebel, Elizabeth K. Hussey & George E. Dukes. (2016) Do All Histamine 2 -Antagonists Cause a Warfarin Drug Interaction? . DICP 23:9, pages 675-679.
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N. H. Brockmeyer, H. Breithaupt, W. Ferdinand, M. von Hattingberg & E. E. Ohnhaus. (1989) Kinetics of oral and intravenous mexiletine: lack of effect of cimetidine and ranitidine. European Journal of Clinical Pharmacology 36:4, pages 375-378.
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A. Francavilla, L. Makowka, L. Polimeno, M. Barone, J. Demetris, J. Prelich, D.H. Van Thiel & T.E. Starzl. (1989) A Dog Model for Acetaminophen-Induced Fulminant Hepatic Failure. Gastroenterology 96:2, pages 470-478.
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Jean-Pierre Aymard, Bernadette Aymard, Patrick Netter, Bernard Bannwarth, Philippe Trechot & François Streiff. (2012) Haematological Adverse Effects of Histamine H2-Receptor Antagonists. Medical Toxicology 3:6, pages 430-448.
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Elena Gaggelli, Nadia Marchettini, Alessandro Sega & Gianni Valensin. (1988) Conformation and dynamics of ranitidine in solution as detected by1H and13C NMR spectroscopy. Magnetic Resonance in Chemistry 26:12, pages 1041-1046.
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Slobodan Rendic & Hans-Heinrich Ruf. (1988) Interaction of stanozolol with cytochrome P-450. Biochemical Pharmacology 37:4, pages 766-768.
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Martin Black. (1987) Hepatotoxic and hepatoprotective potential of histamine (H2)-receptor antagonists. The American Journal of Medicine 83:6, pages 68-75.
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James W. Freston. (1987) Safety perspectives on parenteral H2-receptor antagonists. The American Journal of Medicine 83:6, pages 58-67.
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Ene I. EtteEsther A. Brown-AwalaEttiene E. Essien. (2017) Effect of Ranitidine on Chloroquine Disposition. Drug Intelligence & Clinical Pharmacy 21:9, pages 732-734.
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A. G. renwick, J. Le Vie, V. F. Challenor, D. G. Waller, B. Gruchy & C. F. George. (1987) Factors affecting the pharmacokinetics of nifedipine. European Journal of Clinical Pharmacology 32:4, pages 351-355.
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E Tarrus, J Cami, DJ Roberts, RG Spickett, E Celdran & J Segura. (2012) Accumulation of caffeine in healthy volunteers treated with furafylline.. British Journal of Clinical Pharmacology 23:1, pages 9-18.
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M. Mitchard, A. Harris & B.M. Mullinger. (1987) Ranitidine drug interactions—a literature review. Pharmacology & Therapeutics 32:3, pages 293-325.
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Roger W. Brimblecombe & C. Robin Ganellin. 1987. Drug Discovery and Development. Drug Discovery and Development 353 385 .
R. M. Lee & R. D. McDowall. (1986) RECENT ADVANCES IN PHARMACEUTICAL CHEMISTRY—REVIEW II HISTAMINE H 2 -RECEPTOR ANTAGONISTS . Journal of Clinical Pharmacy and Therapeutics 11:6, pages 389-408.
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Mitchell Nazario. (2016) The Hepatic and Renal Mechanisms of Drug Interactions with Cimetidine. Drug Intelligence & Clinical Pharmacy 20:5, pages 342-348.
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DR Guay, RC Meatherall, JL Chalmers, GR Grahame & RJ Hudson. (2012) Ranitidine does not alter pethidine disposition in man.. British Journal of Clinical Pharmacology 20:1, pages 55-59.
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Harriet G. Oldham & Richard J. Chenery. (1985) Interaction of cimetidine and ranitidine with the FAD monooxygenase in pig liver microsomes. Biochemical Pharmacology 34:13, pages 2398-2401.
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S. Emery, H.G. Oldham, S.J. Norman & R.J. Chenery. (1985) The effect of cimetidine and ranitidine on paracetamol glucuronidation and sulphation in cultured rat hepatocytes. Biochemical Pharmacology 34:9, pages 1415-1421.
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Thomas B. Leonard, D. Gwyn Morgan & John G. Dent. (1985) Ranitidine-acetaminophen interaction: Effects on acetaminophen-induced hepatotoxicity in fischer 344 rats. Hepatology 5:3, pages 480-487.
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H. P. Hoensch, H. Hutzel, W. Kirch & E. E. Ohnhaus. (1985) Isolation of human hepatic microsomes and their inhibition by cimetidine and ranitidine. European Journal of Clinical Pharmacology 29:2, pages 199-206.
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. (1984) Single blind comparative study of ranitidine and cimetidine in patients with gastric ulcer. The Belgian Peptic Ulcer Study Group.. Gut 25:9, pages 999-1002.
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S. Rendić, H. H. Ruf, P. Weber & F. Kajfež. (1984) Cimetidine and ranitidine: Their interaction with human and pig liver microsomes and withpurified cytochrome P-450. European Journal of Drug Metabolism and Pharmacokinetics 9:3, pages 195-200.
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JOHN MEYRICK THOMAS & GEORGE MISIEWICZ. (1984) Histamine H2-receptor Antagonists in the Short- and Long-term Treatment of Duodenal Ulcer. Clinics in Gastroenterology 13:2, pages 501-541.
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L. K. Webster, G. W. Mihaly, D. B. Jones, R. A. Smallwood, J. A. Phillips & F. J. Vajda. (1984) Effect of cimetidine and ranitidine on carbamazepine and sodium valproate pharmacokinetics. European Journal of Clinical Pharmacology 27:3, pages 341-343.
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Timothy S. Gaginella & Jay H. Bauman. (2016) Ranitidine Hydrochloride. Drug Intelligence & Clinical Pharmacy 17:12, pages 873-885.
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U. Klotz & I. Reimann. (1983) Einflu� von Histamin H2-Rezeptorantagonisten auf die hepatische Elimination von ArzneimittelnInfluence of H2-blocking agents on the hepatic elimination of drugs. Klinische Wochenschrift 61:13, pages 625-632.
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B. Benjamin. (1983) Farr sighted. BMJ 286:6383, pages 2063-2064.
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G. Devathasan & Collin Koh. (1982) WERNICKE'S ENCEPHALOPATHY IN PROLONGED FASTING. The Lancet 320:8307, pages 1108-1109.
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R.R. Shah. (1982) SYMPTOMATIC BRADYCARDIA IN ASSOCIATION WITH H2-RECEPTOR ANTAGONISTS. The Lancet 320:8307, pages 1108.
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