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Xenobiotica
the fate of foreign compounds in biological systems
Volume 13, 1983 - Issue 12
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Research Article

The interaction of arylalkylbenzimidazoles and related compounds with microsomal oxidation

M. Murray Department of Pharmacy, University of Sydney, Sydney, NSW, 2006, Australia; Department of Medicine, Sydney University, Westmead Centre, Westmead, NSW, 2145, Australia
&
A. J. Ryan Department of Pharmacy, University of Sydney, Sydney, NSW, 2006, Australia
Pages 707-714 | Received 24 May 1983, Published online: 22 Sep 2008

Citations (15)

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Read on this site (2)

Michael Murray. (1987) Mechanisms of the Inhibition of Cytochrome P 450-Mediated Drug Oxidation by Therapeutic Agents. Drug Metabolism Reviews 18:1, pages 55-81.
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I Skånberg, K-J Hoffmann & C G Regårdh. (1986) Pharmacokinetics and Metabolism of Omeprazole in Animals. Scandinavian Journal of Gastroenterology 21:sup118, pages 92-93.
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Articles from other publishers (13)

Michael Murray. (1986) Inhibition of hepatic microsomal monooxygenase activity by cinchocaine: mechanistic studies and effects of ionization. Journal of Pharmacy and Pharmacology 38:6, pages 472-475.
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S A Ward, G W Mihaly, J F Tjia & D J Back. (1985) The effect of some benzimidazoles on the disposition of antipyrine and tolbutamide from the rat isolated perfused liver. Journal of Pharmacy and Pharmacology 37:1, pages 62-64.
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Stefanie D. Krämer & Bernard Testa. (2009) The Biochemistry of Drug Metabolism – An Introduction. Chemistry & Biodiversity 6:10, pages 1477-1660.
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Lionel Perrin, Fran?ois Andr?Caroline Aninat, R?my Ricoux, Jean-Pierre Mahy, Ning Shangguan, Madeleine M. Joulli?Marcel Delaforge. (2009) Intramolecular hydrogen bonding as a determinant of the inhibitory potency of N-unsubstituted imidazole derivatives towards mammalian hemoproteins. Metallomics 1:2, pages 148-156.
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G.F. Reidy, H.A. Rose, S. Visetson & M. Murray. (1990) Increased glutathione S-transferase activity and glutathione content in an insecticide-resistant strain of Tribolium castaneum (Herbst). Pesticide Biochemistry and Physiology 36:3, pages 269-276.
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Michael Murray & Gordon F. Reidy. (1989) In vitro inhibition of hepatic drug oxidation by thioridazine. Biochemical Pharmacology 38:24, pages 4359-4365.
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Gordon F. Reidy & Michael Murray. (1989) In vitro inhibition of hepatic steroid hydroxylation by tamoxifen, a series of tamoxifen analogues and related compounds. Biochemical Pharmacology 38:1, pages 195-199.
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Michael Murray & Louise Zaluzny. (1988) Comparative effects of antithrombitic and antimycotic N-substituted imidazoles on rat hepatic microsomal steroid and xenobiotic hydroxylases in vitro. Biochemical Pharmacology 37:3, pages 415-420.
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Terry D. Lindstrom, Gary W. Whitaker & Richard P. Pioch. (1987) Inhibition of microsomal biotransformation by a series of nitrogen and oxygen heterocyclic histamine h2-antagonists. Biochemical Pharmacology 36:10, pages 1669-1672.
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Michael Murray. (1987) New heterocyclic modifiers of oxidative drug metabolism—II. Biochemical Pharmacology 36:4, pages 463-468.
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Michael Murray, Ernest Lacey & Geoffrey C. Farrell. (1986) New heterocyclic modifiers of oxidative drug metabolism—I. Biochemical Pharmacology 35:12, pages 1971-1979.
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Michael Murray, Craig B. Marcus & Christopher F. Wilkinson. (2006) Quantitative Structure‐Activity Relationships in the Displacement of the Dihydrosafrole Metabolite‐Cytochrome P‐450 Complex. Quantitative Structure-Activity Relationships 4:1, pages 18-22.
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Michael Murray. (1984) In vitro effects of quinoline derivatives on cytochrome p-450 and aminopyrine n-demethylase activity in rat hepatic microsomes. Biochemical Pharmacology 33:20, pages 3277-3281.
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