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Xenobiotica
the fate of foreign compounds in biological systems
Volume 13, 1983 - Issue 9
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Research Article

The metabolism of 4-substituted-N-ethyl-N-methyl-anilines: II. Some factors influencing α-C- and N-oxidation

J. W. Gorrod Department of Pharmacy, Chelsea College (University of London), Manresa Road, London, SW3 6LX, UK
&
L. H. Patterson Department of Pharmacy, Chelsea College (University of London), Manresa Road, London, SW3 6LX, UK; School of Pharmacy, Leicester Polytechnic, Leicester, LE1 9BH, UK
Pages 513-520 | Received 29 Oct 1982, Accepted 01 Sep 1983, Published online: 22 Sep 2008

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J. M. Dady, S. P. Bradbury, A. D. Hoffman, M. M. Voit & D. L. Olson. (1991) Hepatic microsomal N-hydroxylation of aniline and 4-chloroaniline by rainbow trout (Onchorhyncus mykiss). Xenobiotica 21:12, pages 1605-1620.
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M. Ŝtefek, L. Beneŝ & V. Zelník. (1989) N-oxygenation of stobadine, a γ-carboline antiarrhythmic and cardioprotective agent: The role of flavin-containing monooxygenase. Xenobiotica 19:2, pages 143-150.
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J. W. Gorrod & N. J. Gooderham. (1987) The metabolism of N-benzyl-4-substituted anilines: factors influencing in vitro C- and N-oxidation. Xenobiotica 17:2, pages 165-177.
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J. W. Gorrod & D. Manson. (1986) The metabolism of aromatic amines. Xenobiotica 16:10-11, pages 933-955.
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J. W. Gorrord & L. H. Patterson. (1983) The metabolism of 4-substituted N-ethyl-N-methylanilines: III. Effect of various potential inhibitors, activators and inducers on α-C- and N-oxidation. Xenobiotica 13:9, pages 521-529.
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Articles from other publishers (6)

Paul R. Ortiz de Montellano. 2015. Cytochrome P450. Cytochrome P450 111 176 .
C J Barwell, A N Basma, C A Canham & C Williams. (1986) Kinetics of N,N -Dimethyl Tyramine (Hordenine) Demethylation by Guinea-Pig Liver Microsomes . Journal of Pharmacy and Pharmacology 38:Supplement_12, pages 123P-123P.
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Mark R. Hadley, Harriet G. Oldham, Patrick Camilleri, Lyaquatali A. Damani & Andrew J. Hutt. (1996) Species differences in the stereoselectivity ofN-oxygenation ofN-ethyl-N-methylaniline in vitro. Chirality 8:6, pages 430-440.
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Mark R. Hadley, Harriet G. Oldham, Lyaquatali A. Damani & Andrew J. Hutt. (2004) Asymmetric metabolic N ‐oxidation of N ‐ethyl‐ N ‐methylaniline by purified flavin‐containing monooxygenase . Chirality 6:2, pages 98-104.
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P. Hlavica & I. Golly. 1991. N-Oxidation of Drugs. N-Oxidation of Drugs 71 90 .
P. J. Watkins & J. W. Gorrod. (1987) Studies on thein vitro biological N-oxidation of trimethoprim. European Journal of Drug Metabolism and Pharmacokinetics 12:4, pages 245-251.
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