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Xenobiotica
the fate of foreign compounds in biological systems
Volume 14, 1984 - Issue 7
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Original Article

Saturation of an α,β-unsaturated ketone: A novel xenobiotic biotransformation in mammals

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Pages 503-508 | Received 28 Nov 1983, Published online: 30 Sep 2009

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Ji Yue (Jeff) Zhang, Jiangwei Zhang, Michael Kiffe, Markus Walles, Yi Jin, Joachim Blanz, Jerôme Dayer, Arevalo Sanchez, Chunye Zhang, Lijun Zhang, Ying Huang & Counde Oyang. (2022) Preclinical pharmacokinetics and metabolism of MAK683, a clinical stage selective oral embryonic ectoderm development (EED) inhibitor for cancer treatment. Xenobiotica 52:1, pages 65-78.
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J. C. L. Erve, S. C. Vashishtha, O. Ojewoye, A. Adedoyin, R. Espina, W. DeMaio & R. E. Talaat. (2008) Metabolism of prazosin in rat and characterization of metabolites in plasma, urine, faeces, brain and bile using liquid chromatography/mass spectrometry (LC/MS). Xenobiotica 38:5, pages 540-558.
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Maroua Mbarik, Samuel J. Poirier, Jérémie Doiron, Ayyoub Selka, David A. Barnett, Marc Cormier, Mohamed Touaibia & Marc E. Surette. (2019) Phenolic acid phenethylesters and their corresponding ketones: Inhibition of 5‐lipoxygenase and stability in human blood and HepaRG cells. Pharmacology Research & Perspectives 7:5.
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Terry W. Moore, Shijun Zhu, Ryan Randolph, Mamoru Shoji & James P. Snyder. (2014) Liver S9 Fraction-Derived Metabolites of Curcumin Analogue UBS109. ACS Medicinal Chemistry Letters 5:4, pages 288-292.
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D. Belsito, D. Bickers, M. Bruze, P. Calow, M.L. Dagli, A.D. Fryer, H. Greim, Y. Miyachi, J.H. Saurat & I.G. Sipes. (2013) A toxicological and dermatological assessment of alkyl cyclic ketones when used as fragrance ingredients. Food and Chemical Toxicology 62, pages S1-S44.
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Lushan Yu, Yan Jiang, Lu Wang, Rong Sheng, Yongzhou Hu & Su Zeng. (2013) Metabolism of BYZX in Human Liver Microsomes and Cytosol: Identification of the Metabolites and Metabolic Pathways of BYZX. PLoS ONE 8:3, pages e59882.
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John C. L. Erve, Sarvesh C. Vashishtha, William DeMaio & Rasmy E. Talaat. (2007) Metabolism of Prazosin in Rat, Dog, and Human Liver Microsomes and Cryopreserved Rat and Human Hepatocytes and Characterization of Metabolites by Liquid Chromatography/Tandem Mass Spectrometry. Drug Metabolism and Disposition 35:6, pages 908-916.
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