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Xenobiotica
the fate of foreign compounds in biological systems
Volume 15, 1985 - Issue 4
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Research Article

Metabolism of ethylbenzene in the rat during long-term intermittent inhalation exposure

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Pages 281-286 | Received 07 May 1984, Published online: 22 Sep 2008

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Makoto Take, Tomoki Takeda, Hiroaki Ishikawa, Michiharu Matsumoto, Kasuke Nagano & Shoji Fukushima. (2020) Area under the blood concentration-time curve (AUC) of ethylbenzene concentration in rats: relationship to inhalation and oral administration route-dose. Journal of Environmental Science and Health, Part A 55:14, pages 1596-1603.
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A. Nong, G. Charest-Tardif, R. Tardif, D. F. V. Lewis, L. M. Sweeney, M. L. Gargas & K. Krishnan. (2007) Physiologically Based Modeling of the Inhalation Pharmacokinetics of Ethylbenzene in B6C3F1 Mice∗ . Journal of Toxicology and Environmental Health, Part A 70:21, pages 1838-1848.
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Yin‐tak Woo, David Lai, Joseph Arcos, Mary Argus, Michael Cimino, Steven DcVito & Leonard Keifer. (1997) Mechanism‐based structure‐activity relationship (SAR) analysis of carcinogenic potential of 30 NTP test chemicals∗ . Journal of Environmental Science and Health, Part C 15:2, pages 139-160.
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E. Elovaara, K. Engström, J. Nickels, A. Aito & H. Vainio. (1985) Biochemical and morphological effects of long-term inhalation exposure of rats to ethylbenzene. Xenobiotica 15:4, pages 299-308.
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Articles from other publishers (17)

Achim T. Caspar, Folker Westphal, Markus R. Meyer & Hans H. Maurer. (2017) LC-high resolution-MS/MS for identification of 69 metabolites of the new psychoactive substance 1-(4-ethylphenyl-)-N-[(2-methoxyphenyl)methyl] propane-2-amine (4-EA-NBOMe) in rat urine and human liver S9 incubates and comparison of its screening power with further MS techniques. Analytical and Bioanalytical Chemistry 410:3, pages 897-912.
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A. Hartwig. 2002. The MAK‐Collection for Occupational Health and Safety. The MAK‐Collection for Occupational Health and Safety 1 32 .
Peter F. Infante*Eula Bingham. 2003. Patty's Toxicology. Patty's Toxicology 1 68 .
. 2002. The MAK-Collection for Occupational Health and Safety. The MAK-Collection for Occupational Health and Safety 1 318 .
. 2002. The MAK‐Collection for Occupational Health and Safety. The MAK‐Collection for Occupational Health and Safety 1 30 .
Moiz M. Mumtaz & Hana R. Pohl. 2012. Molecular, Clinical and Environmental Toxicology. Molecular, Clinical and Environmental Toxicology 361 379 .
Benoît Cossec, Frédéric Cosnier, Manuella Burgart, Hervé Nunge & Stéphane Grossmann. (2010) Glutathione pathway in ethylbenzene metabolism: Novel biomarkers of exposure in the rat. Chemosphere 81:10, pages 1334-1341.
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Abby A. Li, Jacques P.J. Maurissen, John F. BarnettJr.Jr., John Foss, Les Freshwater, Robert H. Garman, Vanessa L. Peachee, Sandra J. Hong, Donald G. Stump & James S. Bus. (2010) Oral gavage subchronic neurotoxicity and inhalation subchronic immunotoxicity studies of ethylbenzene in the rat. NeuroToxicology 31:3, pages 247-258.
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I. F. Mao, F. K. Chang & M. L. Chen. (2007) Delayed and Competitively Inhibited Excretion of Urinary Hippuric Acid in Field Workers Coexposed to Toluene, Ethyl Benzene, and Xylene. Archives of Environmental Contamination and Toxicology 53:4, pages 678-683.
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Werner Mellert, Klaus Deckardt, Wolfgang Kaufmann & Bennard van Ravenzwaay. (2006) Ethylbenzene: 4- and 13-week rat oral toxicity. Archives of Toxicology 81:5, pages 361-370.
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A.M. Saillenfait, F. Gallissot, J.P. Sabaté, N. Bourges-Abella, R. Cadot, G. Morel & A.M. Lambert. (2006) Developmental toxicity of combined ethylbenzene and methylethylketone administered by inhalation to rats. Food and Chemical Toxicology 44:8, pages 1287-1298.
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G. Charest-Tardif, R. Tardif & K. Krishnan. (2006) Inhalation pharmacokinetics of ethylbenzene in B6C3F1 mice. Toxicology and Applied Pharmacology 210:1-2, pages 63-69.
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Eric J. Fabian & Manfred Metzler. (2005) Selective metabolism of E-3,4-bis(4-ethylphenyl)hex-3-ene in rat liver microsomes. Archives of Toxicology 80:1, pages 17-26.
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Rogene F. Henderson. 2003. Patty's Toxicology. Patty's Toxicology.
R. von Burg. (2006) Toxicology update. Journal of Applied Toxicology 12:1, pages 69-71.
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F. Gagnaire, A. Ensminger, B. Marignac & J. de Ceaurriz. (2006) Possible involvement of 1,2‐diacetylbenzene in diethylbenzene‐induced neuropathy in rats. Journal of Applied Toxicology 11:4, pages 261-268.
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Herbert L. Holland, Ian M. Carter, P.Chinna Chenchaiah, Shaheer H. Khan, Benito Munoz, Ronald W. Ninniss & Denise Richards. (1985) Fungal hydroxylation of ethyl benzene and derivatives. Tetrahedron Letters 26:52, pages 6409-6412.
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