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Xenobiotica
the fate of foreign compounds in biological systems
Volume 17, 1987 - Issue 5
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Research Article

Dose-dependent pharmacokinetics of cimetidine in the rat

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Pages 595-604 | Received 09 Mar 1986, Published online: 22 Sep 2008

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S. K. Kuwahara, T. J. Shinn, B. D. Schreider, M. L. Phan & A. N. Kotake. (1995) Aminopyrine infusion breath test for the determination of changes in P450 metabolism in vivo. Xenobiotica 25:9, pages 973-980.
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Articles from other publishers (11)

Yoo-Seong Jeong, Anusha Balla, Kwang-Hoon Chun, Suk-Jae Chung & Han-Joo Maeng. (2019) Physiologically-Based Pharmacokinetic Modeling for Drug-Drug Interactions of Procainamide and N-Acetylprocainamide with Cimetidine, an Inhibitor of rOCT2 and rMATE1, in Rats. Pharmaceutics 11:3, pages 108.
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Liam Koehn, Mark Habgood, Yifan Huang, Katarzyna Dziegielewska & Norman Saunders. (2019) Determinants of drug entry into the developing brain. F1000Research 8, pages 1372.
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Martina Ceckova, Josef Reznicek, Birgit Deutsch, Martin F. Fromm & Frantisek Staud. (2018) Efavirenz reduces renal excretion of lamivudine in rats by inhibiting organic cation transporters (OCT, Oct) and multidrug and toxin extrusion proteins (MATE, Mate). PLOS ONE 13:8, pages e0202706.
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Toru Arino, Seiji Karakawa, Yasuyoshi Ishiwata, Masashi Nagata & Masato Yasuhara. (2012) Effect of cimetidine on pentamidine induced hyperglycemia in rats. European Journal of Pharmacology 693:1-3, pages 72-79.
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Urban Fagerholm. (2007) Prediction of human pharmacokinetics — renal metabolic and excretion clearance. Journal of Pharmacy and Pharmacology 59:11, pages 1463-1471.
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Hiromu Katsuda, Mariko Yamashita, Hideyuki Katsura, Jia Yu, Yoshihiro Waki, Naoto Nagata, Yoshimichi Sai & Ken-ichi Miyamoto. (2010) Protecting Cisplatin-Induced Nephrotoxicity with Cimetidine Does Not Affect Antitumor Activity. Biological & Pharmaceutical Bulletin 33:11, pages 1867-1871.
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Tsuyoshi Minematsu, Tadashi Hashimoto, Toshiko Aoki, Takashi Usui & Hidetaka Kamimura. (2008) Role of Organic Anion Transporters in the Pharmacokinetics of Zonampanel, an α-Amino-3-hydroxy-5-methylisoxazole-4-propionate Receptor Antagonist, in Rats. Drug Metabolism and Disposition 36:8, pages 1496-1504.
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K BachmannD PardoeD White. (1996) Scaling basic toxicokinetic parameters from rat to man.. Environmental Health Perspectives 104:4, pages 400-407.
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R. A. Carr, F. M. Pasutto & R. T. Foster. (1998) INFLUENCE OF CIMETIDINE COADMINISTRATION ON THE PHARMACOKINETICS OF SOTALOL ENANTIOMERS IN AN ANAESTHETIZED RAT MODEL: EVIDENCE SUPPORTING ACTIVE RENAL EXCRETION OF SOTALOL. Biopharmaceutics & Drug Disposition 17:1, pages 55-69.
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Lori A. Dostal, Robert P. Weaver & Bernard A. Schwetz. (1990) Excretion of high concentrations of cimetidine and ranitidine into rat milk and their effects on milk composition and mammary gland nucleic acid content. Toxicology and Applied Pharmacology 102:3, pages 430-442.
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Marc Levine, Tom Chang & Gail D. Bellward. (1989) Attenuation of low dose phenobarbital induction of hepatic microsomal aminopyrine N-demethylase activity in rats by cimetidine. Biochemical and Biophysical Research Communications 162:3, pages 1363-1369.
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