Advanced search
Publication Cover
Xenobiotica
the fate of foreign compounds in biological systems
Volume 19, 1989 - Issue 8
Submit an article Journal homepage
20
Views
10
CrossRef citations to date
0
Altmetric
Research Article

Induction of liver microsomal cytochrome P-450 isozymes by 1-(2-chlorophenyl)-N-methyl-N-(1-methylpropyl)-3-isoquinoline carboxamide

M. Totis Centre du Médicament, Université de Nancy, 30 rue du Lionnois, F-5400, Nancy, France
,
P. Kremers Centre du Médicament, Université de Nancy, 30 rue du Lionnois, F-5400, Nancy, France
,
A. M. Batt Centre du Médicament, Université de Nancy, 30 rue du Lionnois, F-5400, Nancy, France
,
J. Van Cantfort Laboratoire de Chimie médicale, Institut de Pathologie B23, Université de Liège, B-4000, Sart Tilman, Belgium
,
G. Siest Centre du Médicament, Université de Nancy, 30 rue du Lionnois, F-5400, Nancy, France
&
J. Gielen Laboratoire de Chimie médicale, Institut de Pathologie B23, Université de Liège, B-4000, Sart Tilman, Belgium
Pages 857-866 | Received 13 Oct 1988, Accepted 17 Mar 1989, Published online: 22 Sep 2008

Citations (10)

Keep up to date with the latest research on this topic with citation updates for this article.

Subscribe to citation updates

Read on this site (2)

Seolsong Kim, Nayoun Kim, Seokjae Park, Yoonjeong Jeon, Jaemeun Lee, Seung-Jun Yoo, Ji-Won Lee, Cheil Moon, Seong-Woon Yu & Eun-Kyoung Kim. (2020) Tanycytic TSPO inhibition induces lipophagy to regulate lipid metabolism and improve energy balance. Autophagy 16:7, pages 1200-1220.
Read now
Bernd Antkowiak & Gerhard Rammes. (2019) GABA(A) receptor-targeted drug development -New perspectives in perioperative anesthesia. Expert Opinion on Drug Discovery 14:7, pages 683-699.
Read now

Articles from other publishers (8)

Carlos Eduardo Sampaio Guedes, Beatriz Rocha Simões Dias, Antonio Luis de Oliveira Almeida Petersen, Kercia Pinheiro Cruz, Niara de Jesus Almeida, Daniela Rodrigues Andrade, Juliana Perrone Bezerra de Menezes, Valéria de Matos Borges & Patricia Sampaio Tavares Veras. (2018) In vitro evaluation of the anti-leishmanial activity and toxicity of PK11195. Memórias do Instituto Oswaldo Cruz 113:4.
Crossref
Li Ma, Hui Zhang, Na Liu, Pei-qi Wang, Wen-zhi Guo, Qiang Fu, Lin-bo Jiao, Ya-qun Ma & Wei-Dong Mi. (2016) TSPO ligand PK11195 alleviates neuroinflammation and beta-amyloid generation induced by systemic LPS administration. Brain Research Bulletin 121, pages 192-200.
Crossref
Rainer Rupprecht, Vassilios Papadopoulos, Gerhard Rammes, Thomas C. Baghai, Jinjiang Fan, Nagaraju Akula, Ghislaine Groyer, David Adams & Michael Schumacher. (2010) Translocator protein (18 kDa) (TSPO) as a therapeutic target for neurological and psychiatric disorders. Nature Reviews Drug Discovery 9:12, pages 971-988.
Crossref
Mariitta Laaksonen, Eila Kaliste-Korhonen, Sirpa Kärenlampi & Osmo Hänninen. (1995) P450 enzyme CYP2B catalyzes the detoxification of diisopropyl fluorophosphate. Chemico-Biological Interactions 94:3, pages 197-213.
Crossref
Luc Ferrari, Régine Herber, Anne-Marie Batt & Gérard Siest. (1993) Differential effects of human recombinant interleukin-1β and dexamethasone on hepatic drug-metabolizing enzymes in male and female rats. Biochemical Pharmacology 45:11, pages 2269-2277.
Crossref
Nathalie Strazielle, Muriel Totis, Régine Herber, Maria Wellman, Anne-Marie Batt & Gérard Siest. (1991) Effects of RP 52028 and phenobarbital on mRNA levels of inducible and constitutive sex-specific cytochrome P450 isozymes in rat liver. Biochemical Pharmacology 42:5, pages 1053-1060.
Crossref
Rachel Perrin, Alain Minn, Jean-François Ghersi-Egea, Marie-Christine Grassiot & Gerard Siest. (1990) Distribution of cytochrome p450 activities towards alkoxyresorufin derivatives in rat brain regions, subcellular fractions and isolated cerebral microvessels. Biochemical Pharmacology 40:9, pages 2145-2151.
Crossref
Muriel Totis, Jacques Magdalou, Sylvie Fournel-Glgleux, Anne-Marie Batt & Gérard Siest. (1989) Induction of UDP-glucuronosyltransferase isozymes in male and female rat liver microsomes by an isoquinoleine derivative (52028 RP). Biochemical Pharmacology 38:20, pages 3634-3638.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.