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Xenobiotica
the fate of foreign compounds in biological systems
Volume 19, 1989 - Issue 11
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Research Article

Metabolism of organonitriles to cyanide by rat nasal tissue enzymes

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Pages 1201-1205 | Received 23 Aug 1988, Accepted 24 Apr 1989, Published online: 22 Sep 2008

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Richard J. Albertini, Christopher R. Kirman & Dale E. Strother. (2023) Acrylonitrile’s genotoxicity profile: mutagenicity in search of an underlying molecular mechanism. Critical Reviews in Toxicology 53:2, pages 69-116.
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Alan G. E. Wilson & Lori J. Hall. (1991) Technology Review: Application of Whole-Body Autoradiography in Toxicology. Toxicology Methods 1:3, pages 147-160.
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Alan R. Dahl & William M. Hadley. (1991) Nasal Cavity Enzymes Involved in Xenobiotic Metabolism: Effects on the Toxicity of Inhalants. Critical Reviews in Toxicology 21:5, pages 345-372.
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K. Simons, T. De Smedt, C. Stove, P. De Paepe, M. Bader, B. Nemery, C. Vleminckx, K. De Cremer, I. Van Overmeire, S. Fierens, B. Mertens, T. Göen, T. Schettgen, H. Van Oyen, J. Van Loco & A. Van Nieuwenhuyse. (2016) Short-term health effects in the general population following a major train accident with acrylonitrile in Belgium. Environmental Research 148, pages 256-263.
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C. R. Kirman, L. M. Sweeney, M. L. Gargas, D. E. Strother, J. J. Collins & R. Deskin. (2008) Derivation of Noncancer Reference Values for Acrylonitrile. Risk Analysis 28:5, pages 1375-1394.
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Alan M. Jeffrey, Michael J. Iatropoulos & Gary M. Williams. (2016) Nasal Cytotoxic and Carcinogenic Activities of Systemically Distributed Organic Chemicals. Toxicologic Pathology 34:7, pages 827-852.
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C.R. Kirman, M.L. Gargas, G.M. Marsh, D.E. Strother, J.E. Klaunig, J.J. Collins & R. Deskin. (2005) Cancer dose–response assessment for acrylonitrile based upon rodent brain tumor incidence: Use of epidemiologic, mechanistic, and pharmacokinetic support for nonlinearity. Regulatory Toxicology and Pharmacology 43:1, pages 85-103.
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Roger McClellan & Rogene HendersonAlan Dahl. 1995. Concepts In Inhalation Toxicology. Concepts In Inhalation Toxicology 175 190 .
Pamela M. Mattes & William B. Mattes. (1992) α-Naphthyl butyrate carboxylesterase activity in human and rat nasal tissue. Toxicology and Applied Pharmacology 114:1, pages 71-76.
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Eva B. Brittebo, Catarina Eriksson & Ingvar Brandt. (1992) Effects of glutathione-modulating agents on the covalent binding and toxicity of dichlobenil in the mouse olfactory mucosa. Toxicology and Applied Pharmacology 114:1, pages 31-40.
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J. L. Lewis, C. E. Rhoades, D. E. Bice, J. R. Harkema, J. A. Hotchkiss, D. M. Sylvester & A. R. Dahl. (2005) Interspecies comparison of cellular localization of the cyanide metabolizing enzyme rhodanese within olfactory mucosa. The Anatomical Record 232:4, pages 620-627.
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