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Xenobiotica
the fate of foreign compounds in biological systems
Volume 22, 1992 - Issue 1
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Research Article

Biological fate of sulphur mustard (1,1'-thiobis(2-chloroethane)): urinary and faecal excretion of 35S by rat after injection or cutaneous application of 35S-labelled sulphur mustard

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Pages 65-75 | Received 20 Mar 1991, Published online: 22 Sep 2008

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Read on this site (9)

Leila Etemad, Mohammad Moshiri & Mahdi Balali-Mood. (2019) Advances in treatment of acute sulfur mustard poisoning – a critical review. Critical Reviews in Toxicology 49:3, pages 191-214.
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Janet M. Benson, Brad M. Tibbetts, Waylon M. Weber & Gary R. Grotendorst. (2011) Uptake, Tissue Distribution, and Excretion of 14C-Sulfur Mustard Vapor Following Inhalation in F344 Rats and Cutaneous Exposure in Hairless Guinea Pigs. Journal of Toxicology and Environmental Health, Part A 74:13, pages 875-885.
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ChristopherM. Timperley, RobinM. Black, Michael Bird, Ian Holden, JoannaL. Mundy & RobertW. Read. (2003) Hydrolysis and Oxidation Products of the Chemical Warfare Agents 1,2-Bis[(2-chloroethyl)thio]ethane Q and 2,2′-Bis(2-chloroethylthio)diethyl Ether T. Phosphorus, Sulfur, and Silicon and the Related Elements 178:9, pages 2027-2046.
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R. M. Black, J. M. Harrison & R. W. Read. (1997) Biological fate of sulphur mustard : in vitro alkylation of human haemoglobin by sulphur mustard. Xenobiotica 27:1, pages 11-32.
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A. Maisonneuve, I. Callebat, L. Debordes & L. Coppet. (1993) Biological fate of sulphur mustard in rat: toxicokinetics and disposition. Xenobiotica 23:7, pages 771-780.
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R. M. Black, K. Brewster, R. J. Clarke, J. L. Hambrook, J. M. Harrison & D. J. Howells. (1993) Metabolism of thiodiglycol (2,2′-thiobis-ethanol): isolation and identification of urinary metabolites following intraperitoneal administration to rat. Xenobiotica 23:5, pages 473-481.
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R. M. Black, K. Brewster, R. J. Clarke, J. L. Hambrook, J. M. Harrison & D. J. Howells. (1992) Biological fate of sulphur mustard, 1,1'-thiobis(2-chloroethane): isolation and identification of urinary metabolites following intraperitoneal administration to rat. Xenobiotica 22:4, pages 405-418.
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Articles from other publishers (15)

Jeffrey D. Laskin, Kevin Ozkuyumcu, Peihong Zhou, Claire R. Croutch, Diane E. Heck, Debra L. Laskin & Laurie B. Joseph. (2023) Skin Models Used to Define Mechanisms of Action of Sulfur Mustard. Disaster Medicine and Public Health Preparedness 17.
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Charlotte A. Hall, Helen L. Lydon, Christopher H. Dalton, J. Kevin Chipman, John S. Graham & Robert P. Chilcott. (2017) The percutaneous toxicokinetics of Sulphur mustard in a damaged skin porcine model and the evaluation of WoundStat™ as a topical decontaminant. Journal of Applied Toxicology 37:9, pages 1036-1045.
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Bin Xu, Cheng Zong, Yajiao Zhang, Tianhong Zhang, Xiaoying Wang, Meiling Qi, Jianfeng Wu, Lei Guo, Peng Wang, Jia Chen, Qin Liu, Hua Xu, Jianwei Xie & Zhenqing Zhang. (2016) Accumulation of intact sulfur mustard in adipose tissue and toxicokinetics by chemical conversion and isotope-dilution liquid chromatography–tandem mass spectrometry. Archives of Toxicology 91:2, pages 735-747.
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Gunda Reddy & Sang Ho Lee. 2015. Wildlife Toxicity Assessments for Chemicals of Military Concern. Wildlife Toxicity Assessments for Chemicals of Military Concern 617 636 .
Zhiyong Nie, Yajiao Zhang, Jia Chen, Ying Lin, Bidong Wu, Yuan Dong, Jianlin Feng, Qin Liu & Jianwei Xie. (2014) Monitoring urinary metabolites resulting from sulfur mustard exposure in rabbits, using highly sensitive isotope-dilution gas chromatography–mass spectrometry. Analytical and Bioanalytical Chemistry 406:21, pages 5203-5212.
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Ying Lin, Yuan Dong, Jia Chen, Chun-Zheng Li, Zhi-Yong Nie, Lei Guo, Qin Liu & Jian-Wei Xie. (2014) Gas chromatographic–tandem mass spectrometric analysis of β-lyase metabolites of sulfur mustard adducts with glutathione in urine and its use in a rabbit cutaneous exposure model. Journal of Chromatography B 945-946, pages 233-239.
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Tina Wismer. 2012. Veterinary Toxicology. Veterinary Toxicology 98 116 .
Tina Wismer. 2009. Handbook of Toxicology of Chemical Warfare Agents. Handbook of Toxicology of Chemical Warfare Agents 721 738 .
Tina Wismer. 2007. Veterinary Toxicology. Veterinary Toxicology 74 91 .
Om Kumar, K. Sugendran & R. Vijayaraghavan. (2001) Protective effect of various antioxidants on the toxicity of sulphur mustard administered to mice by inhalation or percutaneous routes. Chemico-Biological Interactions 134:1, pages 1-12.
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Jim E. Riviere, Charles E. Smith, Kamon Budsaba, James D. Brooks, Eugene J. Olajos, Harry Salem & Nancy A. Monteiro‐Riviere. (2001) Use of methyl salicylate as a simulant to predict the percutaneous absorption of sulfur mustard. Journal of Applied Toxicology 21:2, pages 91-99.
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Robin M. Black, Robert W Read & Daan Noort. 2007. Encyclopedia of Analytical Chemistry. Encyclopedia of Analytical Chemistry 1 32 .
R. P. Chilcott, J. Jenner, W. Carrick, S. A. M. Hotchkiss & P. Rice. (2000) Human skin absorption of bis-2-(chloroethyl)sulphide (sulphur mustard)in vitro. Journal of Applied Toxicology 20:5, pages 349-355.
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P.V Lakshmana Rao, R Vijayaraghavan & A.S.B Bhaskar. (1999) Sulphur mustard induced DNA damage in mice after dermal and inhalation exposure. Toxicology 139:1-2, pages 39-51.
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Jerry W. Spoo, Nancy A. Monteiro-Riviere & Jim E. Riviere. (1995) Detection of sulfur mustard bis (2-chloroethyl) sulfide and metabolites after topical application in the isolated perfused porcine skin flap. Life Sciences 56:17, pages 1385-1394.
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