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Xenobiotica
the fate of foreign compounds in biological systems
Volume 24, 1994 - Issue 1
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Original Article

Biotransformation of carbazeran in guinea pig: Effect of hydralazine pretreatment

D. J. P. Critchley Pharmaceutical Chemistry, School of Pharmacy, University of Bradford, Bradford, BD7 1DP, UK
,
D. J. Rance Department of Drug Metabolism, Pfizer Central Research, Sandwich, Kent, CT13 9, NJ, UK
&
C. Beedham Pharmaceutical Chemistry, School of Pharmacy, University of Bradford, Bradford, BD7 1DP, UK
Pages 37-47 | Received 20 Oct 1993, Published online: 27 Aug 2009

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Christine Beedham. (2020) Aldehyde oxidase; new approaches to old problems. Xenobiotica 50:1, pages 34-50.
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Enrico Garattini & Mineko Terao. (2013) Aldehyde oxidase and its importance in novel drug discovery: present and future challenges. Expert Opinion on Drug Discovery 8:6, pages 641-654.
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Deepak Dalvie, Cathie Xiang, Ping Kang & Sue Zhou. (2013) Interspecies variation in the metabolism of zoniporide by aldehyde oxidase. Xenobiotica 43:5, pages 399-408.
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James Matthew Hutzler, Ronald Scott Obach, Deepak Dalvie & Michael A Zientek. (2013) Strategies for a comprehensive understanding of metabolism by aldehyde oxidase. Expert Opinion on Drug Metabolism & Toxicology 9:2, pages 153-168.
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Enrico Garattini & Mineko Terao. (2012) The role of aldehyde oxidase in drug metabolism. Expert Opinion on Drug Metabolism & Toxicology 8:4, pages 487-503.
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Federica Vacondio, Claudia Silva, Marco Mor & Bernard Testa. (2010) Qualitative structure-metabolism relationships in the hydrolysis of carbamates. Drug Metabolism Reviews 42:4, pages 551-589.
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Mohammad-Reza Rashidi & Hossein Nazemiyeh. (2010) Inhibitory effects of flavonoids on molybdenum hydroxylases activity. Expert Opinion on Drug Metabolism & Toxicology 6:2, pages 133-152.
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Saeed Pirouzpanah, Jalal Hanaee, Seyed-Vali Razavieh & Mohammad-Reza Rashidi. (2009) Inhibitory effects of flavonoids on aldehyde oxidase activity. Journal of Enzyme Inhibition and Medicinal Chemistry 24:1, pages 14-21.
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Articles from other publishers (14)

Shotaro Uehara, Nao Yoneda, Yuichiro Higuchi, Hiroshi Yamazaki & Hiroshi Suemizu. (2020) Human Aldehyde Oxidase 1–Mediated Carbazeran Oxidation in Chimeric TK-NOG Mice Transplanted with Human Hepatocytes. Drug Metabolism and Disposition 48:7, pages 580-586.
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Deepak Dalvie & Li Di. (2019) Aldehyde oxidase and its role as a drug metabolizing enzyme. Pharmacology & Therapeutics 201, pages 137-180.
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Naoki Takaoka, Seigo Sanoh, Katsuhiro Okuda, Yaichiro Kotake, Go Sugahara, Ami Yanagi, Yuji Ishida, Chise Tateno, Yoshitaka Tayama, Kazumi Sugihara, Shigeyuki Kitamura, Mami Kurosaki, Mineko Terao, Enrico Garattini & Shigeru Ohta. (2018) Inhibitory effects of drugs on the metabolic activity of mouse and human aldehyde oxidases and influence on drug–drug interactions. Biochemical Pharmacology 154, pages 28-38.
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Alexander I. Vardavas, Eren Ozcagli, Persefoni Fragkiadaki, Polychronis D. Stivaktakis, Manolis N. Tzatzarakis, Athanasios K. Alegakis, Fotini Vasilaki, Kostas Kaloudis, John Tsiaoussis, Dimitrios Kouretas, Christina Tsitsimpikou, Félix Carvalho & Aristidis M. Tsatsakis. (2018) The metabolism of imidacloprid by aldehyde oxidase contributes to its clastogenic effect in New Zealand rabbits. Mutation Research/Genetic Toxicology and Environmental Mutagenesis 829-830, pages 26-32.
Crossref
Tami L. Swenson & John E. Casida. (2013) Aldehyde Oxidase Importance In Vivo in Xenobiotic Metabolism: Imidacloprid Nitroreduction in Mice. Toxicological Sciences 133:1, pages 22-28.
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Amit S. Kalgutkar, Deepak Dalvie, R. Scott Obach & Dennis A. Smith. 2012. Reactive Drug Metabolites. Reactive Drug Metabolites 43 70 .
Timothy J. Strelevitz, Christine C. Orozco & R. Scott Obach. (2012) Hydralazine As a Selective Probe Inactivator of Aldehyde Oxidase in Human Hepatocytes: Estimation of the Contribution of Aldehyde Oxidase to Metabolic Clearance. Drug Metabolism and Disposition 40:7, pages 1441-1448.
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Alexander V. LyubimovMichael Zientek, Ping Kang, Matthew J. Hutzler & Scott R. Obach. 2011. Encyclopedia of Drug Metabolism and Interactions. Encyclopedia of Drug Metabolism and Interactions 1 59 .
David C. Pryde, Deepak Dalvie, Qiyue Hu, Peter Jones, R. Scott Obach & Thien-Duc Tran. (2010) Aldehyde Oxidase: An Enzyme of Emerging Importance in Drug Discovery. Journal of Medicinal Chemistry 53:24, pages 8441-8460.
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R. Scott Obach, Phuong Huynh, Mary C. Allen & Christine Beedham. (2004) Human Liver Aldehyde Oxidase: Inhibition by 239 Drugs. The Journal of Clinical Pharmacology 44:1, pages 7-19.
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Dieter Lang & Amit Kalgutkar. 2003. Drug Metabolizing Enzymes. Drug Metabolizing Enzymes 483 539 .
Taravat GHAFOURIAN & Mohammad Reza RASHIDI. (2001) Quantitative Study of the Structural Requirements of Phthalazine/Quinazoline Derivatives for Interaction with Human Liver Aldehyde Oxidase.. Chemical and Pharmaceutical Bulletin 49:9, pages 1066-1071.
Crossref
Allan Rettie & Michael Fisher. 1999. Handbook of Drug Metabolism. Handbook of Drug Metabolism 131 151 .
Christine Beedham, Caroline F. Peet, Georgious I. Panoutsopoulos, Helen Carter & John A. Smith. 1995. Current Neurochemical and Pharmacological Aspects of Biogenic Amines - Their Function, Oxidative Deamination and Inhibition. Current Neurochemical and Pharmacological Aspects of Biogenic Amines - Their Function, Oxidative Deamination and Inhibition 345 353 .

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