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Xenobiotica
the fate of foreign compounds in biological systems
Volume 26, 1996 - Issue 3
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Research Article

Induction of cytochrome P450 isoenzymes in cultured precision-cut rat and human liver slices

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Pages 297-306 | Received 20 Sep 1995, Published online: 22 Sep 2008

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Inge AM de Graaf, Geny MM Groothuis & Peter Olinga. (2007) Precision-cut tissue slices as a tool to predict metabolism of novel drugs. Expert Opinion on Drug Metabolism & Toxicology 3:6, pages 879-898.
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C. Meredith, M. P. Scott, A. B. Renwick, R. J. Price & B. G. Lake. (2003) Studies on the induction of rat hepatic CYP1A, CYP2B, CYP3A and CYP4A subfamily form mRNAs in vivo and in vitro using precision-cut rat liver slices. Xenobiotica 33:5, pages 511-527.
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Slobodan Rendic. (2002) Summary of information on human CYP enzymes: human P450 metabolism data. Drug Metabolism Reviews 34:1-2, pages 83-448.
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J. Pan, Q. Xiang, A. B. Renwick, R. J. Price, S. E. Ball, J. Kao, J. A. Scatina & B. G. Lake. (2002) Use of a quantitative real-time reverse transcription-polymerase chain reaction method to study the induction of CYP1A, CYP2B and CYP4A forms in precision-cut rat liver slices. Xenobiotica 32:9, pages 739-747.
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A.-K. Sohlenius-Sternbeck, E. Floby, M. Svedling & A. Orzechowski. (2000) High conservation of both phase I and II drug-metabolizing activities in cryopreserved rat liver slices. Xenobiotica 30:9, pages 891-903.
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B. G. LAKE, J. M. TREDGER, A. B. RENWICK, P. T. BARTON & R. J. PRICE. (1998) 3,3′-Diindolylmethane induces CYP1A2 in cultured precision-cut human liver slices. Xenobiotica 28:8, pages 803-811.
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Slobodan Rendic & Frederick J. Di Carlo. (1997) Human Cytochrome P450 Enzymes: A Status Report Summarizing Their Reactions, Substrates, Inducers, and Inhibitors. Drug Metabolism Reviews 29:1-2, pages 413-580.
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