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Drug and Chemical Toxicology Volume 34, 2011 - Issue 4

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Review Article

Tenuous dose-response correlations for common disease states: case study of cholesterol and perfluorooctanoate/sulfonate (PFOA/PFOS) in the C8 Health Project

Brent D. KergerHSRI, Tallahassee, Florida, USACorrespondence[email protected]

Teri L. CopelandConsultant, Agoura Hills, California, USA

Anthony P. DeCaprioFlorida International University, Miami, Florida, USA

Pages 396-404 | Received 03 Jun 2010, Accepted 15 Apr 2011, Published online: 19 Jul 2011

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https://doi.org/10.3109/01480545.2011.582502

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Xiaohui Wei, Pingping Liu, Danyang Bai, Luyuan Zhang, Hongyan Mao, Wenjing Zhang, Tianqi Chen, Dan Yin, Tianhua Sun, Yanhao Zhang & Wenfen Zhang. (2024) Industrializable and pH-tolerant electropositive imidazolium chloride polymer for high-efficiency removal of perfluoroalkyl carboxylic acids from aqueous solution. Journal of Hazardous Materials 465, pages 133095.
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Anne Loccisano, Autumn Bernal & Brent Kerger. 2003. Patty's Toxicology. Patty's Toxicology 1 76 .

Dauren Mussabek, Anna Söderman, Tomomi Imura, Kenneth M. Persson, Kei Nakagawa, Lutz Ahrens & Ronny Berndtsson. (2022) PFAS in the Drinking Water Source: Analysis of the Contamination Levels, Origin and Emission Rates. Water 15:1, pages 137.
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Linda Dunder, P. Monica Lind, Samira Salihovic, Jordan Stubleski, Anna Kärrman & Lars Lind. (2022) Changes in plasma levels of per- and polyfluoroalkyl substances (PFAS) are associated with changes in plasma lipids - A longitudinal study over 10 years. Environmental Research 211, pages 112903.
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Alfred PoulosAlfred Poulos. 2021. The Secret Life of Chemicals. The Secret Life of Chemicals 143 155 .

Dauren Mussabek, Kenneth M. Persson, Ronny Berndtsson, Lutz Ahrens, Kei Nakagawa & Tomomi Imura. (2020) Impact of the Sediment Organic vs. Mineral Content on Distribution of the Per- and Polyfluoroalkyl Substances (PFAS) in Lake Sediment. International Journal of Environmental Research and Public Health 17:16, pages 5642.
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Dauren Mussabek, Lutz Ahrens, Kenneth M. Persson & Ronny Berndtsson. (2019) Temporal trends and sediment–water partitioning of per- and polyfluoroalkyl substances (PFAS) in lake sediment. Chemosphere 227, pages 624-629.
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Helle Katrine Knutsen, Jan Alexander, Lars Barregård, Margherita Bignami, Beat Brüschweiler, Sandra Ceccatelli, Bruce Cottrill, Michael Dinovi, Lutz Edler, Bettina Grasl‐Kraupp, Christer Hogstrand, Laurentius (Ron) Hoogenboom, Carlo Stefano Nebbia, Isabelle P Oswald, Annette Petersen, Martin Rose, Alain‐Claude Roudot, Christiane Vleminckx, Günter Vollmer, Heather Wallace, Laurent Bodin, Jean‐Pierre Cravedi, Thorhallur Ingi Halldorsson, Line Småstuen Haug, Niklas Johansson, Henk van Loveren, Petra Gergelova, Karen Mackay, Sara Levorato, Mathijs van Manen & Tanja Schwerdtle. (2018) Risk to human health related to the presence of perfluorooctane sulfonic acid and perfluorooctanoic acid in food. EFSA Journal 16:12.
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Liping Lu, Linqing Guo, Meng Li, Tianfang Kang, Shuiyuan Cheng & Wujian Miao. (2016) Investigation of perfluorooctanoic acid induced DNA damage using electrogenerated chemiluminescence associated with charge transfer in DNA. Analytical and Bioanalytical Chemistry 408:25, pages 7137-7145.
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Kevin M. Beggs, Steven R. McGreal, Alex McCarthy, Sumedha Gunewardena, Jed N. Lampe, Christoper Lau & Udayan Apte. (2016) The role of hepatocyte nuclear factor 4-alpha in perfluorooctanoic acid- and perfluorooctanesulfonic acid-induced hepatocellular dysfunction. Toxicology and Applied Pharmacology 304, pages 18-29.
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Anna Mattsson, Anna Kärrman, Rui Pinto & Björn Brunström. (2015) Metabolic Profiling of Chicken Embryos Exposed to Perfluorooctanoic Acid (PFOA) and Agonists to Peroxisome Proliferator-Activated Receptors. PLOS ONE 10:12, pages e0143780.
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Margret Skuladottir, Alfons Ramel, Dorte Rytter, Line Småstuen Haug, Azemira Sabaredzovic, Bodil Hammer Bech, Tine Brink Henriksen, Sjurdur F. Olsen & Thorhallur I. Halldorsson. (2015) Examining confounding by diet in the association between perfluoroalkyl acids and serum cholesterol in pregnancy. Environmental Research 143, pages 33-38.
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Marie Pierre Krafft & Jean G. Riess. (2015) Per- and polyfluorinated substances (PFASs): Environmental challenges. Current Opinion in Colloid & Interface Science 20:3, pages 192-212.
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John P. Vanden Heuvel. (2013) Comment on “Associations between PFOA, PFOS and changes in the expression of genes involved in cholesterol metabolism in humans” by Fletcher et al., Environment International 57-58 (2013) 2–10. Environment International 61, pages 150-153.
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Mitchell B. Rosen, Kaberi P. Das, Carmen R. Wood, Cynthia J. Wolf, Barbara D. Abbott & Christopher Lau. (2013) Evaluation of perfluoroalkyl acid activity using primary mouse and human hepatocytes. Toxicology 308, pages 129-137.
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Sohel Saikat, Irene Kreis, Bethan Davies, Stephen Bridgman & Robie Kamanyire. (2013) The impact of PFOS on health in the general population: a review. Environ. Sci.: Processes Impacts 15:2, pages 329-335.
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L. Lind & P. M. Lind. (2012) Can persistent organic pollutants and plastic‐associated chemicals cause cardiovascular disease?. Journal of Internal Medicine 271:6, pages 537-553.
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Tenuous dose-response correlations for common disease states: case study of cholesterol and perfluorooctanoate/sulfonate (PFOA/PFOS) in the C8 Health Project

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Tenuous dose-response correlations for common disease states: case study of cholesterol and perfluorooctanoate/sulfonate (PFOA/PFOS) in the C8 Health Project

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