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Drug and Chemical Toxicology Volume 39, 2016 - Issue 4
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Research Article

Mutagenicity and preclinical safety assessment of the aqueous extract of Clinacanthus nutans leaves

Elham FarsiSchool of Pharmaceutical Sciences, Universiti Sains Malaysia, Penang, Malaysia,
,
Kameh EsmailliSchool of Pharmaceutical Sciences, Universiti Sains Malaysia, Penang, Malaysia,
,
Armaghan ShafaeiSchool of Pharmaceutical Sciences, Universiti Sains Malaysia, Penang, Malaysia,
,
Pegah Moradi KhaniabadiSchool of Physics, Universiti Sains Malaysia, Penang, Malaysia,
,
Bassel Al HindiSchool of Pharmaceutical Sciences, Universiti Sains Malaysia, Penang, Malaysia,
,
Mohamed B. Khadeer AhamedEman Biodiscovery, Penang, Malaysia, and
,
Doblin SandaiAdvanced Medical and Dental Institute, Universiti Sains Malaysia, Penang, Malaysia,
,
Munavvar Abdul SattarSchool of Pharmaceutical Sciences, Universiti Sains Malaysia, Penang, Malaysia,
,
Zhari IsmailSchool of Pharmaceutical Sciences, Universiti Sains Malaysia, Penang, Malaysia,
,
Amin Malik Shah Abdul MajidSchool of Pharmaceutical Sciences, Universiti Sains Malaysia, Penang, Malaysia,
&
Aman Shah Abdul MajidDepartment of Pharmacology, Quest International University, Perak, MalaysiaCorrespondence[email protected]
 show all
Pages 461-473 | Received 13 Jun 2015, Accepted 21 Feb 2016, Published online: 01 Apr 2016

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Sanghita Das, Achintya Saha, Amartya Banerjee, Danswrang Goyary, Sanjeev Karmakar, Sanjai Kumar Dwivedi & Pronobesh Chattopadhyay. (2023) Toxicological evaluation of a nonlethal riot control combinational formulation upon dermal application using animal models. Cutaneous and Ocular Toxicology 42:3, pages 118-130.
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Srijita Chakrabarti, Johirul Islam, Hemanga Hazarika, Bhaskar Mazumder, Pakalapati Srinivas Raju & Pronobesh Chattopadhyay. (2018) Safety profile of silver sulfadiazine-bFGF-loaded hydrogel for partial thickness burn wounds. Cutaneous and Ocular Toxicology 37:3, pages 258-266.
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Articles from other publishers (8)

Zhandong Ye, Zhiqiang Fang, Dan LiXiaogang Lin & Song Huang. (2023) Exploring the material basis and mechanism of action of clinacanthus nutans in treating renal cell carcinoma based on metabolomics and network pharmacology. Medicine 102:42, pages e35675.
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Wei-Yi Ong, Deron R. Herr, Grace Y. Sun & Teng-Nan Lin. (2022) Anti-Inflammatory Effects of Phytochemical Components of Clinacanthus nutans. Molecules 27:11, pages 3607.
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Anshul Shakya, Sushil Kumar Chaudhary, Hans Raj Bhat & Surajit Kumar Ghosh. (2020) Acute and sub-chronic toxicity studies of Benincasa hispida (Thunb.) cogniaux fruit extract in rodents. Regulatory Toxicology and Pharmacology 118, pages 104785.
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Nur Adeelah Che Ahmad Tantowi, Suhaila Mohamed, Seng Fong Lau & Paisal Hussin. (2020) Comparison of diclofenac with apigenin-glycosides rich Clinacanthus nutans extract for amending inflammation and catabolic protease regulations in osteoporotic-osteoarthritis rat model. DARU Journal of Pharmaceutical Sciences 28:2, pages 443-453.
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Sachinthi S. Amarasiri, Anoja P. Attanayake, Liyanagae D. A. M. Arawwawala, Kamani A. P. W. Jayatilaka & Lakmini K. B. Mudduwa. (2020) Acute and 28-Day Repeated-Dose Oral Toxicity Assessment of Abelmoschus moschatus Medik. in Healthy Wistar Rats . Evidence-Based Complementary and Alternative Medicine 2020, pages 1-14.
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Abdullahi Aliyu, Mohd Rosly Shaari, Nurul Syahirah Ahmad Sayuti, Mohd Farhan Hanif Reduan, Shanmugavelu Sithambaram, Mustapha Mohamed Noordin, Khozirah Shaari & Hazilawati Hamzah. (2020) Subacute Oral Administration of Clinacanthus nutans Ethanolic Leaf Extract Induced Liver and Kidney Toxicities in ICR Mice. Molecules 25:11, pages 2631.
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Leng Wei Khoo, Siew Audrey Kow, Ming Tatt Lee, Chin Ping Tan, Khozirah Shaari, Chau Ling Tham & Faridah Abas. (2018) A Comprehensive Review on Phytochemistry and Pharmacological Activities of Clinacanthus nutans (Burm.f.) Lindau . Evidence-Based Complementary and Alternative Medicine 2018, pages 1-39.
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Jui-Sheng Wu, Mei-Han Kao, Hsin-Da Tsai, Wai-Mui Cheung, Jin-Jer Chen, Wei-Yi Ong, Grace Y. Sun & Teng-Nan Lin. (2017) Clinacanthus nutans Mitigates Neuronal Apoptosis and Ischemic Brain Damage Through Augmenting the C/EBPβ-Driven PPAR-γ Transcription. Molecular Neurobiology 55:7, pages 5425-5438.
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