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Drug and Chemical Toxicology Volume 21, 1998 - Issue 1
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Research Article

Phase III Interlaboratory Study of Fetax, Part 2: Interlaboratory Validation of an Exogenous Metabolic Activation System for Frog Embryo Teratogenesis Assay-Xenopus (Fetax)

Douglas J. Fort THE STOVER GROUP, Stillwater, OK
,
Enos L. Stover THE STOVER GROUP, Stillwater, OK
,
John A. Bantle Department of Zoology, Oklahoma State University, Stillwater, OK
,
James R. Rayburn Department of Zoology, Oklahoma State University, Stillwater, OK
,
Mendi A. Hull Department of Zoology, Oklahoma State University, Stillwater, OK
,
Robert A. Finch U.S. Army Center for Environmental Health Research (Provisional), Fort Derrick, Frederick, MD
,
Dennis T. Burton WYE Research and Education Center, Queenstown, MD
,
Steven D. Turley WYE Research and Education Center, Queenstown, MD
,
Douglas A. Dawson Department of Biology & Toxicology, Ashland University, Ashland, OH
,
Greg Linder ManTech Environmental Research Laboratory, Corvalis, OR
,
David Buchwalter ManTech Environmental Research Laboratory, Corvalis, OR
,
James N. Dumont Oak Ridge National Laboratories, Oak Ridge, TN
,
Marie Kumsher-King Geo-Centers, Inc., U.S. Army Center for Environmental Health Research (Provisional), Fort Derrick, Frederick, MD
&
Angela M. Gaudet-Hull Geo-Centers, Inc., U.S. Army Center for Environmental Health Research (Provisional), Fort Derrick, Frederick, MD
 show all
Pages 1-14 | Published online: 27 Sep 2008

Citations (31)

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Read on this site (4)

ShannonK. Lee, GwenA. Owens & D. N. Rao Veeramachaneni. (2005) Exposure to Low Concentrations of Di-n-butyl Phthalate During Embryogenesis Reduces Survivability and Impairs Development of Xenopus Laevis Frogs. Journal of Toxicology and Environmental Health, Part A 68:10, pages 763-772.
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AbigailE. Mitchell, KulbirS. Bakshi, CaroleA. Kimmel, GermaineM. Buck, MaureenH. Feuston, PaulM. D. Foster, J.M. Friedman, JosephF. Holson, ClaudeL. Hughes, JohnA. Moore, BernardA. Schwetz, AnthonyR. Scialli, WilliamJ. Scott, CharlesV. Vorhees & BarryR. Zirkin. (2004) Evaluating Chemical and other Agent Exosures for Reproductive and Developmental Toxicity. Journal of Toxicology and Environmental Health, Part A 67:15-16, pages 1159-1314.
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Douglas J. Fort, Robert L. Rogers, Robbin R. Paul, Enos L. Stover & Robert A. Finch. (2001) OPTIMIZATION OF AN EXOGENOUS METABOLIC ACTIVATION SYSTEM FOR FETAX. II. PRELIMINARY EVALUATION. Drug and Chemical Toxicology 24:2, pages 117-127.
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Douglas J. Fort, Robert L. Rogers, Enos L. Stover & Robert A. Finch. (2001) OPTIMIZATION OF AN EXOGENOUS METABOLIC ACTIVATION SYSTEM FOR FETAX. I. POST-ISOLATION RAT LIVER MICROSOME MIXTURES. Drug and Chemical Toxicology 24:2, pages 103-115.
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Articles from other publishers (27)

David Pamies, Carmen Estevan, Eugenio Vilanova & Miguel A. Sogorb. 2022. Reproductive and Developmental Toxicology. Reproductive and Developmental Toxicology 107 125 .
Efstathios Nikolaidis. 2022. Reproductive and Developmental Toxicology. Reproductive and Developmental Toxicology 93 106 .
Cristina Viriato, Fernanda Menezes França, Diego Sales Santos, Adriana Sacioto Marcantonio, Cintia Badaró-Pedroso & Cláudia Maris Ferreira. (2021) Evaluation of the potential teratogenic and toxic effect of the herbicide 2,4-D (DMA® 806) in bullfrog embryos and tadpoles (Lithobates catesbeianus). Chemosphere 266, pages 129018.
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Efstathios Nikolaidis. 2017. Reproductive and Developmental Toxicology. Reproductive and Developmental Toxicology 211 224 .
David Pamies, Carmen Estevan, Eugenio Vilanova & Miguel A. Sogorb. 2017. Reproductive and Developmental Toxicology. Reproductive and Developmental Toxicology 193 209 .
Isabelle Mouche, Laure Malésic & Olivier Gillardeaux. 2017. Drug Safety Evaluation. Drug Safety Evaluation 311 324 .
Lingling Hu, Jingmin Zhu, Jeanette M. Rotchell, Lijiao Wu, Jinjuan Gao & Huahong Shi. (2015) Use of the enhanced frog embryo teratogenesis assay- Xenopus (FETAX) to determine chemically-induced phenotypic effects. Science of The Total Environment 508, pages 258-265.
Crossref
Isabelle Leconte & Isabelle Mouche. 2013. Teratogenicity Testing. Teratogenicity Testing 403 421 .
Rex Denton, Kimberly Brannen & Bruce D. Car. 2012. Predictive Approaches in Drug Discovery and Development. Predictive Approaches in Drug Discovery and Development 331 351 .
M. Pratten, Bhavesh K. Ahir, H. Smith-Hurst, S. Memon, P. Mutch & P. Cumberland. 2012. Developmental Toxicology. Developmental Toxicology 115 146 .
David Pamies, Carmen Estevan Martínez, Miguel A. Sogorb & Eugenio Vilanova. 2011. Reproductive and Developmental Toxicology. Reproductive and Developmental Toxicology 135 146 .
Efstathios Nikolaidis. 2011. Reproductive and Developmental Toxicology. Reproductive and Developmental Toxicology 111 121 .
Isabelle Mouche, Laure Malesic & Olivier Gillardeaux. 2011. Drug Safety Evaluation. Drug Safety Evaluation 257 269 .
Karen Augustine‐Rauch, Cindy X. Zhang & Julieta M. Panzica‐Kelly. (2010) In vitro developmental toxicology assays: A review of the state of the science of rodent and zebrafish whole embryo culture and embryonic stem cell assays. Birth Defects Research Part C: Embryo Today: Reviews 90:2, pages 87-98.
Crossref
E. A. Severtsova & A. S. Severtsov. (2007) Interpopulation comparison of variations in gastrulation of Rana arvalis and Rana ridibunda occurring under the conditions of anthropogenic contamination of water bodies. Russian Journal of Developmental Biology 38:4, pages 233-245.
Crossref
Douglas J. Fort, Robert L. Rogers, John H. Thomas, William A. Hopkins & Christian Schlekat. (2006) Comparative Developmental Toxicity of Nickel to Gastrophryne carolinensis, Bufo terrestris, and Xenopus laevis. Archives of Environmental Contamination and Toxicology 51:4, pages 703-710.
Crossref
Jeremy A. Lavine, Ashley J. Rowatt, Tatyana Klimova, Aric J. Whitington, Emelyne Dengler, Catherine Beck & Wade H. Powell. (2005) Aryl Hydrocarbon Receptors in the Frog Xenopus laevis: Two AhR1 Paralogs Exhibit Low Affinity for 2,3,7,8-Tetrachlorodibenzo-p-Dioxin (TCDD). Toxicological Sciences 88:1, pages 60-72.
Crossref
Douglas Fort & Robert Rogers. 2005. Techniques in Aquatic Toxicology, Volume 2. Techniques in Aquatic Toxicology, Volume 2.
Douglas J. Fort, Robert L. Rogers, John H. Thomas, Brody O. Buzzard, Andra M. Noll & Clinton D. Spaulding. (2004) Comparative sensitivity of Xenopus tropicalis and Xenopus laevis as test species for the FETAX model . Journal of Applied Toxicology 24:6, pages 443-457.
Crossref
Stephanie L. Fraker & Geoffrey R. Smith. (2004) Direct and interactive effects of ecologically relevant concentrations of organic wastewater contaminants on Rana pipiens tadpoles . Environmental Toxicology 19:3, pages 250-256.
Crossref
Rosalba Gornati, Claudio Monetti, Davide Vigetti, Stefano Bosisio, Salvador Fortaner, Enrico Sabbioni, Giovanni Bernardini & Mariangela Prati. (2019) Arsenic Toxicity and HSP70 Expression in Xenopus laevis Embryos . Alternatives to Laboratory Animals 30:6, pages 597-603.
Crossref
Douglas J. Fort & Robbin R. Paul. (2002) Enhancing the predictive validity of Frog Embryo Teratogenesis Assay— Xenopus (FETAX) . Journal of Applied Toxicology 22:3, pages 185-191.
Crossref
Mariangela Prati, Rosalba Gornati, Patrizia Boracchi, Elia Biganzoli, Salvador Fortaner, Romano Pietra, Enrico Sabbioni & Giovanni Bernardini. (2019) A Comparative Study of the Toxicity of Mercury Dichloride and Methylmercury, Assayed by the Frog Embryo Teratogenesis Assay-Xenopus (FETAX) . Alternatives to Laboratory Animals 30:1, pages 23-32.
Crossref
Perry J Blackshear, Wi S Lai, Judith M Thorn, Elizabeth A Kennington, Nickolas G StaffaJr.Jr., D.Troy Moore, Gerard G Bouffard, Stephen M Beckstrom-Sternberg, Jeffrey W Touchman, Maria de Fatima Bonaldo & M.Bento Soares. (2001) The NIEHS Xenopus maternal EST project: interim analysis of the first 13,879 ESTs from unfertilized eggs. Gene 267:1, pages 71-87.
Crossref
Mariangela Prati, Elia Biganzoli, Patrizia Boracchi, Marina Tesauro, Claudio Monetti & Giovanni Bernardini. (2000) Ecotoxicological soil evaluation by FETAX. Chemosphere 41:10, pages 1621-1628.
Crossref
Douglas J. Fort, Enos L. Stover, John A. Bantle & Robert A. Finch. (2000) Evaluation of the developmental toxicity of thalidomide using frog embryo teratogenesis assay?Xenopus (FETAX): biotransformation and detoxification. Teratogenesis, Carcinogenesis, and Mutagenesis 20:1, pages 35-47.
Crossref
John A. Bantle, Robert A. Finch, Douglas J. Fort, Enos L. Stover, Mendi Hull, Marie Kumsher-King & Angela M. Gaudet-Hull. (1999) Phase III interlaboratory study of FETAX part 3. FETAX validation using 12 compounds with and without an exogenous metabolic activation system. Journal of Applied Toxicology 19:6, pages 447-472.
Crossref

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