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Experimental Lung Research Volume 15, 1989 - Issue 1
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Original Article

Intraphagosomal pH in Alveolar Macrophages Studied with Fluorescein-Labeled Amorphous Silica Particles

Kristina Nyberg Section of Lung Medicine, Unit of Environmental Hygiene, Institute of Environmental Medicine, Stockholm, Sweden; Department of Environmental Hygiene, Karolinska Institute, Stockholm, Sweden; The Wenner-Gren Institute, Biology Building, University of Stockholm, Stockholm, Sweden
,
Anne Johansson Section of Lung Medicine, Unit of Environmental Hygiene, Institute of Environmental Medicine, Stockholm, Sweden; The Wenner-Gren Institute, Biology Building, University of Stockholm, Stockholm, Sweden; Department of Environmental Hygiene, Karolinska Institute, Stockholm, Sweden
&
Per Camner Section of Lung Medicine, Unit of Environmental Hygiene, Institute of Environmental Medicine, Stockholm, Sweden; The Wenner-Gren Institute, Biology Building, University of Stockholm, Stockholm, Sweden; Department of Environmental Hygiene, Karolinska Institute, Stockholm, Sweden
Pages 49-62 | Received 25 Oct 1987, Accepted 10 Mar 1988, Published online: 02 Jul 2009

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Russell M. Potter, John W. Hoffman & John G. Hadley. (2023) Predicting the in vitro dissolution rate constant of mineral wool fibers from fiber composition. Inhalation Toxicology 35:1-2, pages 40-47.
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Emma Innes, Humphrey H. P. Yiu, Polly McLean, William Brown & Matthew Boyles. (2021) Simulated biological fluids – a systematic review of their biological relevance and use in relation to inhalation toxicology of particles and fibres. Critical Reviews in Toxicology 51:3, pages 217-248.
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Sean J. O’Keefe, Bryce N. Feltis, Terrence J. Piva, Terence W. Turney & Paul F. A. Wright. (2016) ZnO nanoparticles and organic chemical UV-filters are equally well tolerated by human immune cells. Nanotoxicology 10:9, pages 1287-1296.
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Wolfgang G. Kreyling, Peter Dirscherl, George A. Ferron, Peter Heilmann, Markus Josten, Ursula Miaskowski, Maria Neuner, Peter Reitmeir, Lutz Ruprecht, Gaby Schumann, Shinji Takenaka, Axel Ziesenis, Joachim Heyder. (1999) HEALTH EFFECTS OF SULFUR-RELATED ENVIRONMENTAL AIR POLLUTION. III. Nonspecific Respiratory Defense Capacities. Inhalation Toxicology 11:5, pages 391-422.
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Klas Philipson, Rolf Falk, Jörgen Gustafsson & Per Camner. (1996) Long-Term Lung Clearance of 195Au-Labeled Teflon Particles in Humans. Experimental Lung Research 22:1, pages 65-83.
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K. Nyberg, K. Nessa, A. Johansson, C. Jarstrand & P. Camner. (1996) Alveolar macrophage response to yeasts and inert particles. Journal of Medical and Veterinary Mycology 34:1, pages 11-17.
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Walter Eastes, Keith J. Morris, Arthur Morgan, Kirsty A. Launder, Clare G. Collier, James A. Davis, Stephanie M. Mattson & John G. Hadley. (1995) Dissolution of Glass Fibers in the Rat Lung Following Intratracheal Instillation. Inhalation Toxicology 7:2, pages 197-213.
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M. Lundborg, U. Johard, A. Johansson, A. Eklund, R. Falk, W. Kreyling & P. Camner. (1995) Phagolysosomal Morphology and Dissolution of Cobalt Oxide Particles by Human and Rabbit Alveolar Macrophages. Experimental Lung Research 21:1, pages 51-66.
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R. A. Harper, C. Stirling, K. M. S. Townsend, W. G. Kreyling & G. Patrick. (1994) Intracellular Particle Dissolution in Macrophages Isolated from the Lung of the Fischer (F-344) Rat. Experimental Lung Research 20:2, pages 143-156.
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W. G. Kreyling, K. Nyberg, D. Nolibé, C. G. Collier, P. Camner, P. Heilmann, P. N. Lirsac, M. Lundborg & E. Matejkova. (1991) Interspecies Comparison of Phagolysosomal pH in Alveolar Macrophages. Inhalation Toxicology 3:1, pages 91-100.
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Kristina Nyberg, Uno Johansson, Ingemar Rundquist & Per Camner. (1989) Estimation of pH in Individual Alveolar Macrophage Phagolysosomes. Experimental Lung Research 15:4, pages 499-510.
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Günter Oberdörster & Thomas A.J. Kuhlbusch. (2018) In vivo effects: Methodologies and biokinetics of inhaled nanomaterials. NanoImpact 10, pages 38-60.
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Antoun El Chemaly & Nicolas Demaurex. (2012) Do Hv1 proton channels regulate the ionic and redox homeostasis of phagosomes?. Molecular and Cellular Endocrinology 353:1-2, pages 82-87.
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Aleksandr B. Stefaniak, M. Abbas Virji & Gregory A. Day. (2011) Dissolution of beryllium in artificial lung alveolar macrophage phagolysosomal fluid. Chemosphere 83:8, pages 1181-1187.
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Winfried Möller, Winfried Barth, Martin Kohlhäufl, Karl Häussinger & Wolfgang G Kreyling. (2006) Motion and twisting of magnetic particles ingested by alveolar macrophages in the human lung: effect of smoking and disease. BioMagnetic Research and Technology 4:1.
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Aleksandr B. Stefaniak, Gregory A. Day, Mark D. Hoover, Patrick N. Breysse & Ronald C. Scripsick. (2006) Differences in dissolution behavior in a phagolysosomal simulant fluid for single-constituent and multi-constituent materials associated with beryllium sensitization and chronic beryllium disease. Toxicology in Vitro 20:1, pages 82-95.
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Winfried Möller, David M Brown, Wolfgang G Kreyling & Vicki Stone. (2005) Ultrafine particles cause cytoskeletal dysfunctions in macrophages: role of intracellular calcium. Particle and Fibre Toxicology 2:1.
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A.B. Stefaniak, R.A. Guilmette, G.A. Day, M.D. Hoover, P.N. Breysse & R.C. Scripsick. (2005) Characterization of phagolysosomal simulant fluid for study of beryllium aerosol particle dissolution. Toxicology in Vitro 19:1, pages 123-134.
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Wolfgang Kreyling & Gerhard Scheuch. 2000. Particle-Lung Interactions. Particle-Lung Interactions 323 376 .
T.W. Hesterberg, G. Chase, C. Axten, W.C. Miller, R.P. Musselman, O. Kamstrup, J. Hadley, C. Morscheidt, D.M. Bernstein & P. Thevenaz. (1998) Biopersistence of Synthetic Vitreous Fibers and Amosite Asbestos in the Rat Lung Following Inhalation. Toxicology and Applied Pharmacology 151:2, pages 262-275.
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Kirsi Luoto, Mikko Holopainen, Juhani Kangas, Pentti Kalliokoski & Kai Savolainen. (1998) Dissolution of Short and Long Rockwool and Glasswool Fibers by Macrophages in Flowthrough Cell Culture. Environmental Research 78:1, pages 25-37.
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N F Johnson. (1994) Phagosomal pH and glass fiber dissolution in cultured nasal epithelial cells and alveolar macrophages: a preliminary study.. Environmental Health Perspectives 102:suppl 5, pages 97-102.
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K. Nyberg, A. Johansson, P. Camner, U. Johard & A. Eklund. (2016) Phagolysosomal pH in Alveolar Macrophages from Smokers and Nonsmokers. Human & Experimental Toxicology 13:3, pages 175-179.
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Neil F. Johnson & Kirk R. Maples. 1994. Cellular and Molecular Effects of Mineral and Synthetic Dusts and Fibres. Cellular and Molecular Effects of Mineral and Synthetic Dusts and Fibres 23 37 .
M LundborgR FalkA JohanssonW KreylingP Camner. (1992) Phagolysosomal pH and dissolution of cobalt oxide particles by alveolar macrophages.. Environmental Health Perspectives 97, pages 153-157.
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K NybergU JohanssonA JohanssonP Camner. (1992) Phagolysosomal pH in alveolar macrophages.. Environmental Health Perspectives 97, pages 149-152.
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P HeilmannW BeiskerU MiaskowskiP CamnerW G Kreyling. (1992) Intraphagolysosomal pH in canine and rat alveolar macrophages: flow cytometric measurements.. Environmental Health Perspectives 97, pages 115-120.
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W. G. Kreyling, W. Beisker, U. Miaskowski, M. Neuner & P. Heilmann. 1992. Environmental Hygiene III. Environmental Hygiene III 19 22 .
W. G. Kreyling, J. J. Godleski, S. T. Kariya, R. M. Rose & J. D. Brain. (1990) In Vitro Dissolution of Uniform Cobalt Oxide Particles by Human and Canine Alveolar Macrophages . American Journal of Respiratory Cell and Molecular Biology 2:5, pages 413-422.
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W. Stahlhofen, W. Möller & J. Godleski. (1990) Relaxation measurements with spherical magnetic particles in the human lungs. Journal of Aerosol Science 21:3, pages 355-362.
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W. G. Kreyling & M. Neuner. 1990. Environmental Hygiene II. Environmental Hygiene II 217 220 .

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