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Original Article

Liposomes and Pulmonary Alveolar Macrophages: Functional and Morphologic Interactions

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Pages 687-705 | Received 18 Dec 1989, Accepted 02 Oct 1990, Published online: 02 Jul 2009

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Paul Zarogoulidis, Ekaterini Chatzaki, Konstantinos Porpodis, Kalliopi Domvri, Wolfgang Hohenforst-Schmidt, Eugene P Goldberg, Nikos Karamanos & Konstantinos Zarogoulidis. (2012) Inhaled chemotherapy in lung cancer: future concept of nanomedicine. International Journal of Nanomedicine 7, pages 1551-1572.
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M. Fujihara, K. Ikebuchi, M. Yamaguchi, H. Abe, K. Niwa & S. Sekiguchi. (1998) Effects of Liposome-Encapsulated Hemoglobin on Phorbol Ester-Induced Superoxide Production and Expression of Costimulatory Molecules by Monocytes in Vitro. Artificial Cells, Blood Substitutes, and Biotechnology 26:5-6, pages 487-495.
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Hans Schreier. (1994) Pulmonary Delivery of Liposomal Drugs. Journal of Liposome Research 4:1, pages 229-238.
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Luis Constantino, Reeta T. Mehta, M. Eugénia Cruz & Gabriel Lopez-berestein. (1993) Formulation and Toxicity of Liposomes Containing Rifampicin. Journal of Liposome Research 3:2, pages 275-301.
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Kenneth L. Brigham & Hans Schreier. (1993) Cationic Liposomes and DNA Delivery. Journal of Liposome Research 3:1, pages 31-49.
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Kevin M.G. Taylor & Stephen J. Fan. (1993) Liposomes for Drug Delivery to the Respiratory Tract. Drug Development and Industrial Pharmacy 19:1-2, pages 123-142.
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M. A. Myers, D. A. Thomas, L. Straub, D. W. Soucy, R. W. Niven, M. Kaltenbach, C. I. Hood, H. Schreier & R. J. Gonzalez-Rothi. (1993) Pulmonary Effects of Chronic Exposure to Liposome Aerosols in Mice. Experimental Lung Research 19:1, pages 1-19.
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Hans Schreier. (1992) Liposome Aerosols. Journal of Liposome Research 2:2, pages 145-184.
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Articles from other publishers (31)

Xichun Qin, Yeqing Zhou, Yuzhuo Wang, Ziyao Wang, Yun Wang, Jiali Chen, Lidong Zhu, Xiaoyu Quan, Zhiwei Liu, Hao Zhang, Liqun Jiang, Hongyan Dong & Zhongming Zhang. (2021) Preparation and Characterization of Protein-loaded PFC Nanoemulsions for the Treatment of Heart Diseases by Pulmonary Administration. European Journal of Pharmaceutical Sciences 158, pages 105690.
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Gauthami Pulivendala, Swarna Bale & Chandraiah Godugu. (2019) Inhalation of sustained release microparticles for the targeted treatment of respiratory diseases. Drug Delivery and Translational Research 10:2, pages 339-353.
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William M. GwinnMayanga C. KapitaPing M. WangMark F. Cesta & William J. MartinIIII. (2011) Synthetic liposomes are protective from bleomycin-induced lung toxicity. American Journal of Physiology-Lung Cellular and Molecular Physiology 301:2, pages L207-L217.
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Parthiban SelvamIbrahim M. El-SherbinyHugh D.C. Smyth. (2011) Swellable Hydrogel Particles for Controlled Release Pulmonary Administration Using Propellant-Driven Metered Dose Inhalers. Journal of Aerosol Medicine and Pulmonary Drug Delivery 24:1, pages 25-34.
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Chwei-Jang Chiou, Li-Ping Tseng, Ming-Chung Deng, Pei-Rong Jiang, Shang-Li Tasi, Tze-Wen Chung, Yi-You Huang & Der-Zen Liu. (2009) Mucoadhesive liposomes for intranasal immunization with an avian influenza virus vaccine in chickens. Biomaterials 30:29, pages 5862-5868.
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Shyamali Mukherjee, William L. Stone, Hongsong Yang, Milton G. Smith & Salil K. Das. (2009) Protection of half sulfur mustard gas–induced lung injury in guinea pigs by antioxidant liposomes. Journal of Biochemical and Molecular Toxicology 23:2, pages 143-153.
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Laszlo M. HoeselMichael A. FlierlAndreas D. NiederbichlerDaniel RittirschShannon D. McClintockJayne S. ReubenMatthew J. PiankoWilliam StoneHongsong YangMilton SmithJ. Vidya SarmaPeter A. Ward. (2008) Ability of Antioxidant Liposomes to Prevent Acute and Progressive Pulmonary Injury. Antioxidants & Redox Signaling 10:5, pages 963-972.
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Valerie A. Brown & Pamela A. Wilkins. (2006) Advanced Techniques in the Diagnosis and Management of Infectious Pulmonary Diseases in Horses. Veterinary Clinics of North America: Equine Practice 22:2, pages 633-651.
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A Benoit, Y Huang, J Proctor, G Rowden & R Anderson. (2006) Effects of alveolar macrophage depletion on liposomal vaccine protection against respiratory syncytial virus (RSV). Clinical and Experimental Immunology 145:1, pages 147-154.
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Shannon D. McClintock, Laszlo M. Hoesel, Salil K. Das, Gerd O. Till, Thomas Neff, Robin G. Kunkel, Milton G. Smith & Peter A. Ward. (2006) Attenuation of half sulfur mustard gas-induced acute lung injury in rats. Journal of Applied Toxicology 26:2, pages 126-131.
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Ann M. Lee, Allison D. Fryer, Nico van Rooijen & David B. Jacoby. (2004) Role of macrophages in virus-induced airway hyperresponsiveness and neuronal M 2 muscarinic receptor dysfunction . American Journal of Physiology-Lung Cellular and Molecular Physiology 286:6, pages L1255-L1259.
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Cary Mobley & Günther Hochhaus. 2001. Drug Targeting Technology. Drug Targeting Technology.
David J. Hackam, Roberto J. Botelho, Carola Sjolin, Ori D. Rotstein, John M. Robinson, Alan D. Schreiber & Sergio Grinstein. (2001) Indirect Role for COPI in the Completion of Fcγ Receptor-mediated Phagocytosis. Journal of Biological Chemistry 276:21, pages 18200-18208.
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JIRO FUJITA, C. MAGNUS SKÖLD, DAVID M. DAUGHTON, RONALD F. ERTL, JIRO TAKAHARA & STEPHEN I. RENNARD. (1999) Modulation of Elastase Binding to Elastin by Human Alveolar Macrophage–derived Lipids. American Journal of Respiratory and Critical Care Medicine 160:3, pages 802-807.
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HANS SCHREIER. 1998. Medical Applications of Liposomes. Medical Applications of Liposomes 473 486 .
J Conley, H Yang, T Wilson, K Blasetti, V Di Ninno, G Schnell & J P Wong. (1997) Aerosol delivery of liposome-encapsulated ciprofloxacin: aerosol characterization and efficacy against Francisella tularensis infection in mice.. Antimicrobial Agents and Chemotherapy 41:6, pages 1288-1292.
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Elizabeth Pretzer, Diana Flasher & Nejat Düzgüneş. (1997) Inhibition of human immunodeficiency virus type-1 replication in macrophages and H9 cells by free or liposome-encapsulated L-689,502, an inhibitor of the viral protease. Antiviral Research 34:1, pages 1-15.
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Michael DiMatteo & Mark J. Reasor. (1997) Modulation of Silica-Induced Pulmonary Toxicity by Dexamethasone-Containing Liposomes. Toxicology and Applied Pharmacology 142:2, pages 411-421.
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Pramod Gupta, John Cannon & Akwete Adjei. (1996) Liposomal formulations of ABT-077: In vitro characterization studies. International Journal of Pharmaceutics 140:1, pages 119-129.
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Todd Weaver, Chris L. Hall, Diane L. Kachel, Robert P. Ward, Mark D. Williams, Douglas G. Perry, Paul Wisniowski & William J. MartinIIII. (1996) Assessment of in vivo attachment/phagocytosis by alveolar macrophages. Journal of Immunological Methods 193:2, pages 149-156.
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Hans Schreier & Susan M. Sawyer. (1996) Liposomal DNA vectors for cystic fibrosis gene therapy. Current applications, limitations, and future directions. Advanced Drug Delivery Reviews 19:1, pages 73-87.
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Xian Ming Zeng, Gary Peter Martin & Christopher Marriott. (1995) The controlled delivery of drugs to the lung. International Journal of Pharmaceutics 124:2, pages 149-164.
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Richard Desjardins, Krzysztof Krzystyniak, Hélène-Marie Thérien, Wanda Banska, Pierre Tancrede & Michel Fournier. (1995) Immunoactivating potential of multilamellar liposome vesicles (MLV) in murine popliteal lymph node (PLN) test. International Journal of Immunopharmacology 17:5, pages 367-374.
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Douglas G. Perry & William J. MartinIIII. (1995) Fluorescent liposomes as quantitative markers of phagocytosis by alveolar macrophages. Journal of Immunological Methods 181:2, pages 269-285.
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A. de Haan, H.J. Geerligs, J.P. Huchshorn, G.J.M. van Scharrenburg, A.M. Palache & J. Wilschut. (1995) Mucosal immunoadjuvant activity of liposomes: induction of systemic IgG and secretory IgA responses in mice by intranasal immunization with an influenza subunit vaccine and coadministered liposomes. Vaccine 13:2, pages 155-162.
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A. de Haan, J.F.C. Tomee, J.P. Huchshorn & J. Wilschut. (1995) Liposomes as an immunoadjuvant system for stimulation of mucosal and systemic antibody responses against inactivated measles virus administered intranasally to mice. Vaccine 13:14, pages 1320-1324.
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G. M. TREMBLAY, H.‐M. THÉRIEN, H. ROCHELEAU & Y. CORMIER. (2008) Liposomal dexamethasone effectiveness in the treatment of hypersensitivity pneumonitis in mice. European Journal of Clinical Investigation 23:10, pages 656-661.
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Hans Schreier, Ricardo J. Gonzalez-Rothi & Arlene A. Stecenko. (1993) Pulmonary delivery of liposomes. Journal of Controlled Release 24:1-3, pages 209-223.
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T. Cserhåti & M. Szögyi. (1993) Interaction of phospholipids with proteins and peptides. New advances III. International Journal of Biochemistry 25:2, pages 123-146.
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Hans Schreier, Kenneth J. McNicol, Michael Ausborn, David M. Soucy, Hartmut Derendorf, Arlene A. Stecenko & Ricardo J. Gonzalez-Rothi. (1992) Pulmonary delivery of amikacin liposomes and acute liposome toxicity in the sheep. International Journal of Pharmaceutics 87:1-3, pages 183-193.
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Burkhard V. Wichert, Ricardo J. Gonzalez-Rothi, Leslie E. Straub, Birgit M. Wichert & Hans Schreier. (1992) Amikacin liposomes: characterization, aerosolization, and in vitro activity against Mycobacterium avium-intracellulare in alveolar macrophages. International Journal of Pharmaceutics 78:1-3, pages 227-235.
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