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Experimental Lung Research Volume 18, 1992 - Issue 3
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Original Article

Deposition and Dispersion of Aerosols in the Airways of the Human Respiratory Tract: The Effect of Particle Size

Gerhard Scheuch GSF Forschungszentrum für Umwelt- und Gesundheit, Institut für Biophysikalische Strahlenforschung, Paul-Ehrlich-Strasse 20, D-6000, Frankfurt/Main, Germany
&
Willi Stahlhofen GSF Forschungszentrum für Umwelt- und Gesundheit, Institut für Biophysikalische Strahlenforschung, Paul-Ehrlich-Strasse 20, D-6000, Frankfurt/Main, Germany
Pages 343-358 | Received 14 Mar 1991, Accepted 25 Jul 1991, Published online: 02 Jul 2009

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Puneet Chopra, Vijay Kanoje, Arvind Semwal & Abhijit Ray. (2008) Therapeutic potential of inhaled p38 mitogen-activated protein kinase inhibitors for inflammatory pulmonary diseases. Expert Opinion on Investigational Drugs 17:10, pages 1411-1425.
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G. Scheuch, W. Stahlhofen, C. P. Fang & M. Lippmann. (1995) Dispersion of Aerosol Particles in an Airway Cast of a Dog. Experimental Lung Research 21:4, pages 519-534.
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Ching-Ping Fang, Julie Esch Wilson, Dalia M. Spektor & Morton Lippmann. (1993) Effect of Lung Airway Branching Pattern and Gas Composition on Particle Deposition in Bronchial Airways: III. Experimental Studies with Radioactively Tagged Aerosol in Human and Canine Lungs. Experimental Lung Research 19:3, pages 377-396.
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Sebastian Canisius. (2021) Hintergründe der Aerosolmedizin. Pneumo News 13:6, pages 35-39.
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Nahyun Lee, Dae Yong Jang, Do Hyeon Lee, Haengdueng Jeong, Ki Taek Nam, Dal-Woong Choi & Kyung-Min Lim. (2021) Local Toxicity of Biocides after Direct and Aerosol Exposure on the Human Skin Epidermis and Airway Tissue Models. Toxics 9:2, pages 29.
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Larry G. Berglund, Sirkka Rissanen, Kirsi Jussila, Jonathan W. Kaufman, Päivi Piirilä, Kai M. Savolainen, Pentti Kalliokoski, Pertti Pasanen, Matti Viluksela, Ulf Landström, Pekka Saarinen, Jaana Rysä & Risto Juvonen. 2020. Industrial Ventilation Design Guidebook. Industrial Ventilation Design Guidebook 111 226 .
Sebastian P. Hertel, Gerhard Winter & Wolfgang Friess. (2015) Protein stability in pulmonary drug delivery via nebulization. Advanced Drug Delivery Reviews 93, pages 79-94.
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Thomas Meyer, Peter Reitmeir, Peter Brand, Christiane Herpich, Knut Sommerer, Anja Schulze, Gerhard Scheuch & Stephen Newman. (2011) Effects of formoterol and tiotropium bromide on mucus clearance in patients with COPD. Respiratory Medicine 105:6, pages 900-906.
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Hemal Tandel, Kiruba Florence & Ambikanandan Misra. 2011. Challenges in Delivery of Therapeutic Genomics and Proteomics. Challenges in Delivery of Therapeutic Genomics and Proteomics 429 479 .
Gerhard Scheuch, Martin J. Kohlhaeufl, Peter Brand & Ruediger Siekmeier. (2006) Clinical perspectives on pulmonary systemic and macromolecular delivery. Advanced Drug Delivery Reviews 58:9-10, pages 996-1008.
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James Gentry. 2004. Aerosols Handbook. Aerosols Handbook 1 17 .
Chantal Darquenne & G.Kim Prisk. (2003) Effect of gravitational sedimentation on simulated aerosol dispersion in the human acinus. Journal of Aerosol Science 34:4, pages 405-418.
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Sylvia Verbanck, Daniël Schuermans, Manuel Paiva & Walter Vincken. (2001) Saline aerosol bolus dispersion. II. The effect of conductive airway alteration. Journal of Applied Physiology 90:5, pages 1763-1769.
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Sylvia Verbanck, Daniël Schuermans, Walter Vincken & Manuel Paiva. (2001) Saline aerosol bolus dispersion. I. The effect of acinar airway alteration. Journal of Applied Physiology 90:5, pages 1754-1762.
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LARRY G. BERGLUND, JONATHAN W. KAUFMAN, ULF LANDSTRöM, KAI M. SAVOLAINEN & PENTTI KALLIOKOSKI. 2001. Industrial Ventilation Design Guidebook. Industrial Ventilation Design Guidebook 173 353 .
D. C. Cipolla, I. Gonda, S. Shak, I. Kovesdi, R. Crystal & T. D. Sweeney. (2000) Coarse Spray Delivery to a Localized Region of the Pulmonary Airways for Gene Therapy. Human Gene Therapy 11:2, pages 361-371.
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Chantal Darquenne, John B. West & G. Kim Prisk. (1999) Dispersion of 0.5- to 2-μm aerosol in μG and hypergravity as a probe of convective inhomogeneity in the lung. Journal of Applied Physiology 86:4, pages 1402-1409.
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. (1997) Alternative Routes of Drug Administration—Advantages and Disadvantages (Subject Review). Pediatrics 100:1, pages 143-152.
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WERNER HOFMANN. (1996) Modeling Techniques for Inhaled Particle Deposition: The State of the Art. Journal of Aerosol Medicine 9:3, pages 369-388.
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GERHARD SCHEUCH, WILLI STAHLHOFEN & JOACHIM HEYDER. (1996) An Approach to Deposition and Clearance Measurements in Human Airways. Journal of Aerosol Medicine 9:1, pages 35-41.
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Werner Hofmann. 1996. Aerosol Inhalation: Recent Research Frontiers. Aerosol Inhalation: Recent Research Frontiers 91 102 .
A H Hashish, A G Bailey & T J Williams. (1994) Modelling the effect of charge on selective deposition of particles in a diseased lung using aerosol boli. Physics in Medicine and Biology 39:12, pages 2247-2262.
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Gerhard Scheuch. (1994) Particle recovery from human conducting airways after shallow aerosol bolus inhalation. Journal of Aerosol Science 25:5, pages 957-973.
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David A Edwards. (1994) A general theory of the macrotransport of nondepositing particles in the lung by convective dispersion. Journal of Aerosol Science 25:3, pages 543-565.
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A.H. HASHISH, A.G. BAILEY & T.J. WILLIAMS. (1994) Selective Deposition of Pulsed Charged Aerosols in the Human Lung. Journal of Aerosol Medicine 7:2, pages 167-171.
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Gerhard Scheuch & Willi Stahlhofen. (1992) The recovery of 1?m aerosol particles from large human airways. Journal of Aerosol Science 23, pages 477-481.
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