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Original Article

Release of paclitaxel from polylactide-co-glycolide (PLGA) microparticles and discs under irradiation

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Pages 317-327 | Received 27 Mar 2002, Accepted 10 Oct 2002, Published online: 02 Jul 2010

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Jakub Szlęk, Adam Pacławski, Raymond Lau, Renata Jachowicz & Aleksander Mendyk. (2013) Heuristic modeling of macromolecule release from PLGA microspheres. International Journal of Nanomedicine 8, pages 4601-4611.
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Leticia I. Cabezas, Ignacio Gracia, Antonio de Lucas & Juan F. Rodríguez. (2014) Validation of a Mathematical Model for the Description of Hydrophilic and Hydrophobic Drug Delivery from Biodegradable Foams: Experimental and Comparison Using Indomethacin as Released Drug. Industrial & Engineering Chemistry Research 53:21, pages 8866-8873.
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Kelly F. Martins, André D. Messias, Fábio L. Leite & Eliana A.R. Duek. (2014) Preparation and characterization of paclitaxel-loaded PLDLA microspheres. Materials Research 17:3, pages 650-656.
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Zhiping Zhang, Songwei Tan & Si-Shen Feng. (2012) Vitamin E TPGS as a molecular biomaterial for drug delivery. Biomaterials 33:19, pages 4889-4906.
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Ulya Badıllı, Tangül Şen & Nilüfer Tarımcı. (2011) Microparticulate Based Topical Delivery System of Clobetasol Propionate. AAPS PharmSciTech 12:3.
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Sudhir H. Ranganath, Yilong Fu, Davis Y. Arifin, Irene Kee, Lin Zheng, How-Sung Lee, Pierce K.-H. Chow & Chi-Hwa Wang. (2010) The use of submicron/nanoscale PLGA implants to deliver paclitaxel with enhanced pharmacokinetics and therapeutic efficacy in intracranial glioblastoma in mice. Biomaterials 31:19, pages 5199-5207.
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Lai Yeng Lee, Sudhir Hulikal Ranganath, Yilong Fu, Jasmine Limin Zheng, How Sung Lee, Chi-Hwa Wang & Kenneth A. Smith. (2009) Paclitaxel release from micro-porous PLGA disks. Chemical Engineering Science 64:21, pages 4341-4349.
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Hwee Yun Tan, Effendi Widjaja, Freddy Boey & Say Chye Joachim Loo. (2009) Spectroscopy techniques for analyzing the hydrolysis of PLGA and PLLA. Journal of Biomedical Materials Research Part B: Applied Biomaterials 91B:1, pages 433-440.
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Hui-Hua Huang, Chuang-Long He, Hong-Sheng Wang & Xiu-Mei Mo. (2009) Preparation of core-shell biodegradable microfibers for long-term drug delivery. Journal of Biomedical Materials Research Part A 90A:4, pages 1243-1251.
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Sudhir Hulikal Ranganath, Irene Kee, William B. Krantz, Pierce Kah-Hoe Chow & Chi-Hwa Wang. (2009) Hydrogel Matrix Entrapping PLGA-Paclitaxel Microspheres: Drug Delivery with Near Zero-Order Release and Implantability Advantages for Malignant Brain Tumour Chemotherapy. Pharmaceutical Research 26:9, pages 2101-2114.
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Benjamin Y.S. Ong, Sudhir H. Ranganath, Lai Yeng Lee, Fan Lu, How-Sung Lee, Nikolaos V. Sahinidis & Chi-Hwa Wang. (2009) Paclitaxel delivery from PLGA foams for controlled release in post-surgical chemotherapy against glioblastoma multiforme. Biomaterials 30:18, pages 3189-3196.
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B. Conti, R. Dorati, C. Colonna & I. Genta. (2009) Effects of ionizing radiation sterilization on microparticulate drug delivery systems based on poly-α-hydroxyacids: an overview. Journal of Drug Delivery Science and Technology 19:2, pages 99-112.
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Sudhir H. Ranganath & Chi-Hwa Wang. (2008) Biodegradable microfiber implants delivering paclitaxel for post-surgical chemotherapy against malignant glioma. Biomaterials 29:20, pages 2996-3003.
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Dušan Ražem & Branka Katušin-Ražem. (2008) The effects of irradiation on controlled drug delivery/controlled drug release systems. Radiation Physics and Chemistry 77:3, pages 288-344.
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Lai Yeng Lee, Chi Hwa Wang & Kenneth A. Smith. (2008) Supercritical antisolvent production of biodegradable micro- and nanoparticles for controlled delivery of paclitaxel. Journal of Controlled Release 125:2, pages 96-106.
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John K. Jackson, Tawny Hung, Kevin Letchford & Helen M. Burt. (2007) The characterization of paclitaxel-loaded microspheres manufactured from blends of poly(lactic-co-glycolic acid) (PLGA) and low molecular weight diblock copolymers. International Journal of Pharmaceutics 342:1-2, pages 6-17.
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Helen E. Williams, Jodanna Huxley, Mike Claybourn, Jonathan Booth, Matthew Hobbs, Elizabeth Meehan & Brian Clark. (2006) The effect of γ-irradiation and polymer composition on the stability of PLG polymer and microspheres. Polymer Degradation and Stability 91:9, pages 2171-2181.
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Sonia Lavisse, Angelo Paci, Valerie Rouffiac, Cecile Adotevi, Paule Opolon, Pierre Peronneau, Philippe Bourget, Alain Roche, Michel Perricaudet, Elias Fattal & Nathalie Lassau. (2005) In Vitro Echogenicity Characterization of Poly[lactide-coglycolide] (PLGA) Microparticles and Preliminary In Vivo Ultrasound Enhancement Study for Ultrasound Contrast Agent Application. Investigative Radiology 40:8, pages 536-544.
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Pieter J. Emans, Ketie Saralidze, Menno L. W. Knetsch, Marion J. J. Gijbels, Roel Kuijer & Leo H. Koole. (2005) Development of new injectable bulking agents: Biocompatibility of radiopaque polymeric microspheres studied in a mouse model. Journal of Biomedical Materials Research Part A 73A:4, pages 430-436.
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Fumiyoshi ISHII & Tomoko NII. (2004) Particulate Drug Carriers as a Field of Nano-Technology (2) : Therapeutic Application. Oleoscience 4:9, pages 367-372,360.
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