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Research Article

Factorial design based optimization of the formulation of albumin microspheres containing adriamycin

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Pages 147-160 | Received 29 Feb 1988, Accepted 16 Mar 1988, Published online: 27 Sep 2008

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Vandana Kharb, Vikas Anand Saharan, Kapil Dev, Hemant Jadhav & Suresh Purohit. (2014) Formulation, evaluation and 32 full factorial design-based optimization of ondansetron hydrochloride incorporated taste masked microspheres. Pharmaceutical Development and Technology 19:7, pages 839-852.
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S. Bozdağ, Y. Çapan, İ. Vural, T. Dalkara, A. L. Dogan, D. Guc, A. A. Hİncal & P. P. Deluca. (2004) In vitro cytotoxicity of mitoxantrone-incorporated albumin microspheres on acute promyelocytic leukaemia cells. Journal of Microencapsulation 21:7, pages 751-760.
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Viney Chawla, Ashok K. Tiwary & Sunil Gupta. (2000) Characterization of Polyvinylalcohol Microspheres of Diclofenac Sodium: Application of Statistical Design. Drug Development and Industrial Pharmacy 26:6, pages 675-680.
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Seham A. Elkheshen, Sabry S. Badawi & Alia A. Badawi. (1996) Optimization of a Reconstitutable Suspension of Rifampicin Using 24 Factorial Design. Drug Development and Industrial Pharmacy 22:7, pages 623-630.
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M. Açikgöz, H. S. KaŞ, M. Orman & A. A. Hincal. (1996) Chitosan microspheres of diclofenac sodium: I. application of factorial design and evaluation of release kinetics. Journal of Microencapsulation 13:2, pages 141-159.
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M. A. Onur, I. Vural, n. Başçi, R. Pamir, T. Coşkun, A. Işimer, H. S. Kaş, S. Beksaç, A. A. Hincal & A. Tümer. (1994) Effect of encapsulation of chloramphenicol in albumin microspheres on its in vitro transfer across the human placenta. Journal of Microencapsulation 11:6, pages 657-662.
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M. A. Onur, I. Vurai, H. S. Kaα, A. A. Hincal, T. Coskun, G. Kanra & A. Tümer. (1993) Decrease in the placental transfer of chloramphenicol when administered in albumin microspheres into rats. Journal of Microencapsulation 10:3, pages 367-374.
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M. Farivar, H. S. Kaα, L. Öner & A. A. Hincal. (1993) Factorial design-based optimization of the formulation of isosorbide-5-mononitrate microcapsules. Journal of Microencapsulation 10:3, pages 309-317.
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I. Vural, H. S. Kasl, A. A. Hincal & G. Cavé. (1990) Cyclophosphamide loaded albumin microspheres II. Release characteristics. Journal of Microencapsulation 7:4, pages 511-516.
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P. K. Gupta & C. T. Hung. (1989) Albumin Microspheres I: Physico-Chemical Characteristics. Journal of Microencapsulation 6:4, pages 427-462.
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Articles from other publishers (8)

Waseem Kaialy, Gary P. Martin, Hassan Larhrib, Martyn D. Ticehurst, Ewa Kolosionek & Ali Nokhodchi. (2012) The influence of physical properties and morphology of crystallised lactose on delivery of salbutamol sulphate from dry powder inhalers. Colloids and Surfaces B: Biointerfaces 89, pages 29-39.
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Gayathri V. Patil. (2003) Biopolymer albumin for diagnosis and in drug delivery. Drug Development Research 58:3, pages 219-247.
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Kwon -Yeon Weon, Kyung -Tae Lee & Sung -Hoon Seo. (2000) Optimization study on the formulation of roxithromycin dispersible tablet using experimental design. Archives of Pharmacal Research 23:5, pages 507-512.
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Ya Min Wang, Hitoshi Sato, Isao Adachi & Isamu Horikoshi. (1996) Optimization of the Formulation Design of Chitosan Microspheres Containing Cisplatin. Journal of Pharmaceutical Sciences 85:11, pages 1204-1210.
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A. Peter Snyder. (1996) Qualitative and quantitative characterization of a microencapsulated protein with pyrolysis-atmospheric pressure ionization mass spectrometry. Chemometrics and Intelligent Laboratory Systems 32:2, pages 233-243.
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A. J. Hickey, Y. Tian, D. Parasrampuria & M. Kanke. (2006) Biliary elimination of bromsulphthalein, phenolphthalein, and doxorubicin released from microspheres following intravenous administration. Biopharmaceutics & Drug Disposition 14:2, pages 181-186.
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Pramod K. Gupta & Hung Cheung-Tak. (1990) Albumin microspheres. V. Evaluation of parameters controlling the efficacy of magnetic microspheres in the targeted delivery of adriamycin in rats. International Journal of Pharmaceutics 59:1, pages 57-67.
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P.K. Gupta & C.T. Hung. (1990) Comparative disposition of adriamycin delivered via magnetic albumin microspheres in presence and absence of magnetic field in rats. Life Sciences 46:7, pages 471-479.
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