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Research Article

Changing the pH of the external aqueous phase may modulate protein entrapment and delivery from poly(lactide-co-glycolide) microspheres prepared by a w/o/w solvent evaporation method

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Pages 421-430 | Received 15 Apr 1997, Accepted 20 Jul 1997, Published online: 27 Sep 2008

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Raghavendra C. Mundargi, V. Ramesh Babu, Vidhya Rangaswamy, Pradip Patel & Tejraj M. Aminabhavi. (2008) Nano/micro technologies for delivering macromolecular therapeutics using poly(d,l-lactide-co-glycolide) and its derivatives. Journal of Controlled Release 125:3, pages 193-209.
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Barbara C Baudner, Marzia M Giuliani, J.Coos Verhoef, Rino Rappuoli, Hans E Junginger & Giuseppe Del Giudice. (2003) The concomitant use of the LTK63 mucosal adjuvant and of chitosan-based delivery system enhances the immunogenicity and efficacy of intranasally administered vaccines. Vaccine 21:25-26, pages 3837-3844.
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Rajesh H. Parikh, Jolly R. Parikh, Rajesh R. Dubey, Heena N. Soni & Kishor N. Kapadia. (2003) Poly(D,L-Lactide-Co-Glycolide) microspheres containing 5-fluorouracil: Optimization of process parameters. AAPS PharmSciTech 4:2, pages 14-21.
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John K Jackson, Linda S Liang, William L Hunter, Mark Reynolds, Jennifer A Sandberg, Chris Springate & Helen M Burt. (2002) The encapsulation of ribozymes in biodegradable polymeric matrices. International Journal of Pharmaceutics 243:1-2, pages 43-55.
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Elias Fattal, Sophie Pecquet, Patrick Couvreur & Antoine Andremont. (2002) Biodegradable microparticles for the mucosal delivery of antibacterial and dietary antigens. International Journal of Pharmaceutics 242:1-2, pages 15-24.
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Olivier Lambert, Oscar Nagele, Veronique Loux, Jean-Daniel Bonny & Laurent Marchal-Heussler. (2000) Poly(ethylene carbonate) microspheres: manufacturing process and internal structure characterization. Journal of Controlled Release 67:1, pages 89-99.
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Lin Yang & Paschalis Alexandridis. (2000) Physicochemical aspects of drug delivery and release from polymer-based colloids. Current Opinion in Colloid & Interface Science 5:1-2, pages 132-143.
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Sophie Pecquet, Eliana Leo, Rodolphe Fritsché, Andréa Pfeifer, Patrick Couvreur & Elias Fattal. (2000) Oral tolerance elicited in mice by β-lactoglobulin entrapped in biodegradable microspheres. Vaccine 18:13, pages 1196-1202.
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Judith Rojas, Huguette Pinto-Alphandary, Eliana Leo, Sophie Pecquet, Patrick Couvreur & Elias Fattal. (1999) Optimization of the encapsulation and release of β-lactoglobulin entrapped poly(dl-lactide-co-glycolide) microspheres. International Journal of Pharmaceutics 183:1, pages 67-71.
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Elias Fattal, Fabiana Quaglia, Pramod Gupta & Gayle Brazeau. 1999. Injectable Drug Development. Injectable Drug Development 355 378 .
Nissim Garti & Chris Bisperink. (1998) Double emulsions: Progress and applications. Current Opinion in Colloid & Interface Science 3:6, pages 657-667.
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