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Original Article

Estimation of therapeutic gain in clinical trials involving hyperthermia and radiotherapy

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Pages 165-178 | Received 01 Dec 1985, Published online: 09 Jul 2009

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Read on this site (14)

Akke Bakker, Jacoba van der Zee, Geertjan van Tienhoven, H. Petra Kok, Coen R. N. Rasch & Hans Crezee. (2019) Temperature and thermal dose during radiotherapy and hyperthermia for recurrent breast cancer are related to clinical outcome and thermal toxicity: a systematic review. International Journal of Hyperthermia 36:1, pages 1023-1038.
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. (2006) Letter to the editor. International Journal of Hyperthermia 22:5, pages 433-447.
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J. Haveman, J. Van Der Zee, J. Wondergem, J. F. Hoogeveen & M. C. C. M. Hulshof. (2004) Effects of hyperthermia on the peripheral nervous system: a review. International Journal of Hyperthermia 20:4, pages 371-391.
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P. D. Maguire, T. V. Samulski, L. R. Prosnitz, E. L. Jones, G. L. Rosner, B. Powers, L. W. Layfield, D. M. Brizel, S. P. Scully, J. M. Harrelson, M. W. Dewhirst. (2001) A phase II trial testing the thermal dose parameter CEM43° T90 as a predictor of response in soft tissue sarcomas treated with pre-operative thermoradiotherapy. International Journal of Hyperthermia 17:4, pages 283-290.
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Y. Hiraki, M. Nakajo, N. Miyaji, T. Takeshita, H. Churei & M. Ogita. (1998) Effectiveness of RF capacitive hyperthermia combined with radiotherapy for Stages III and IV oro-hypopharyngeal cancers: A non-randomized comparison between thermoradiotherapy and radiotherapy. International Journal of Hyperthermia 14:5, pages 445-457.
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D. S. Kapp. (1996) A phase III study on hyperthermia in head and neck canine tumours: Not hot enough. International Journal of Hyperthermia 12:3, pages 437-441.
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S. McChesney Gillette, M. W. Dewhirst, E. L. Gillette, D. E. Thrall, R. L. Page, B. E. Powers, S. J. Withrow, G. Rosner, C. Wong & D. A. Sim. (1992) Response of canine soft tissue sarcomas to radiation or radiation plus hyperthermia: a randomized phase II study. International Journal of Hyperthermia 8:3, pages 309-320.
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P. Sminia, J. Haveman, J.D.P. Van Dijk & J.J.G.W. Hendriks. (1991) Enhancement by Hyperthermia of the ‘Early Delayed’ and ‘Late Delayed’ Radiation Response of the Rat Cervical Spinal Cord. International Journal of Radiation Biology 59:1, pages 259-271.
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Donald E. Thrall, Mark W. Dewhirst, Rodney L. Page, Thaddeus V. Samulski, Deboroah A. McLeod & James R. Oleson. (1990) A comparison of temperatures in canine solid tumours during local and whole-body hyperthermia administered alone and simultaneously. International Journal of Hyperthermia 6:2, pages 305-317.
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Sunao Egawa, Iwao Tsukiyama, Yuichi Kajiura, Yasuyuki Akine, Takashi Ogino, Kenichi Takayasu, Hisatoshi Fukuma, Yasuo Beppu & Kiyoshi Mukai. (1989) Characteristics of the response of soft tissue sarcoma to hyperthermia: The correlation between temperature distribution, radiological examination and histology. International Journal of Hyperthermia 5:1, pages 23-35.
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Daniel S. Kapp, Peter Fessenden, Thaddeus V. Samulski, Malcolm A. Bagshaw, Richard S. Cox, Eric R. Lee, Allen W. Lohrbach, John L. Meyer & Stavros D. Prionas. (1988) Stanford University institutional report. Phase I evaluation of equipment for hyperthermia treatment of cancer. International Journal of Hyperthermia 4:1, pages 75-115.
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J. M. Thompson, Y. A. Dhoodhat, N. M. Bleehen & N. T. Gorman. (1988) Microwave hyperthermia in the treatment of spontaneous canine tumours: an analysis of treatment parameters and tumour response. International Journal of Hyperthermia 4:4, pages 383-399.
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Jens Overgaard & Marie Overgaard. (1987) Hyperthermia as an adjuvant to radiotherapy in the treatment of malignant melanoma. International Journal of Hyperthermia 3:6, pages 483-501.
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Patrick Hung-Ju Kao, Chia-Hung Chen, Yuk-Wah Tsang, Chen-Si Lin, Hsin-Chien Chiang, Cheng-Chung Huang, Mau-Shin Chi, Kai-Lin Yang, Wen-Tyng Li, Shang-Jyh Kao, Carrie Anne Minnaar, Kwan-Hwa Chi & Yu-Shan Wang. (2020) Relationship between Energy Dosage and Apoptotic Cell Death by Modulated Electro-Hyperthermia. Scientific Reports 10:1.
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Melissa J. Grimm, Evan R. Zynda & Elizabeth A. Repasky. 2010. Prokaryotic and Eukaryotic Heat Shock Proteins in Infectious Disease. Prokaryotic and Eukaryotic Heat Shock Proteins in Infectious Disease 267 306 .
Abeer M. Al-Ghananeem, Zaineb F. Albayati, Ahmad Malkawi, Vijayakumar N. Sonar, Michael L. Freeman & Peter A. Crooks. (2007) A pharmacokinetic study on Z-(±)-2-(1-benzylindole-3-yl-methylene)azabicyclo[2.2.2]octane-3-ol; a novel radio-sensitization agent. Cancer Chemotherapy and Pharmacology 60:6, pages 915-919.
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Tai Cheng-Jeng, Wang Wei-Hsu, Chen Po-Min & Hsieh Jui-Chien. (1999) Hyperthermia therapy for low blood supplied tumors: a model of computer simulation. Hyperthermia therapy for low blood supplied tumors: a model of computer simulation.
Donald E. Thrall, Deborah M. Prescott, Thaddeus V. Samulski, Gary L. Rosner, David L. Denman, Roberto L. Legorreta, Richard K. Dodge, Rodney L. Page, J.Mark Cline, Jihjong Lee, Beth C. Case, Sydney M. Evans, James R. Oleson & Mark W. Dewhirst. (1996) Radiation plus local hyperthermia versus radiation plus the combination of local and whole-body hyperthermia in canine sarcomas. International Journal of Radiation Oncology*Biology*Physics 34:5, pages 1087-1096.
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M. Heinrich Seegenschmiedt, Peter Fessenden & Clare C. VernonM. Heinrich Seegenschmiedt, Gunther Klautke, Ralph Seidel & Paul R. Stauffer. 1996. Thermoradiotherapy and Thermochemotherapy. Thermoradiotherapy and Thermochemotherapy 207 262 .
M. W. Dewhirst. 1995. Thermoradiotherapy and Thermochemotherapy. Thermoradiotherapy and Thermochemotherapy 123 136 .
A. G. Visser & G. C. van Rhoon. 1995. Thermoradiotherapy and Thermochemotherapy. Thermoradiotherapy and Thermochemotherapy 453 472 .
F. M. Waterman. 1995. Thermoradiotherapy and Thermochemotherapy. Thermoradiotherapy and Thermochemotherapy 331 360 .
M. Heinrich Seegenschmiedt, Peter Martus, Rainer Fietkau, Heinrich Iro, Luther W. Brady & Rolf Sauer. (1994) Multivariate analysis of prognostic parameters using interstitial thermoradiotherapy (IHT-IRT): Tumor and treatment variables predict outcome. International Journal of Radiation Oncology*Biology*Physics 29:5, pages 1049-1063.
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M. H. Seegenschmiedt, R. Sauer, C. Miyamoto & L. W. Brady. 1993. Interstitial and Intracavitary Thermoradiotherapy. Interstitial and Intracavitary Thermoradiotherapy 271 287 .
M. H. Seegenschmiedt, R. Sauer, R. Fietkau, H. Iro & L. W. Brady. 1993. Interstitial and Intracavitary Thermoradiotherapy. Interstitial and Intracavitary Thermoradiotherapy 241 256 .
M. H. Seegenschmiedt. 1993. Interstitial and Intracavitary Thermoradiotherapy. Interstitial and Intracavitary Thermoradiotherapy 193 209 .
Daniel S Kapp, Richard S Cox, Peter Fessenden, John L Meyer, Stavros D Prionas, Eric R Lee & Malcolm A Bagshaw. (1992) Parameters predictive for complications of treatment with combined hyperthermia and radiation therapy. International Journal of Radiation Oncology*Biology*Physics 22:5, pages 999-1008.
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M. H. Seegenschmiedt, R. Sauer, L. W. Brady & U. L. Karlsson. 1992. Interstitial Hyperthermia. Interstitial Hyperthermia 135 154 .
W. Hurter, F. Reinbold & W.J. Lorenz. (1991) A dipole antenna for interstitial microwave hyperthermia. IEEE Transactions on Microwave Theory and Techniques 39:6, pages 1048-1054.
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W. Hürter, F. Reinbold & W.J. Lorenz. (1991) Eine Dipolantenne für die interstitielle Mikrowellenhyperthermie. Zeitschrift für Medizinische Physik 1:4, pages 173-177.
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Srinath Sundararaman, David L. Denman, Roberto A. Legorreta, Alvis E. Foster, Kevin P. Redmond, Howard R. Elson, Angela M. Born, R.C. Samaratunga, G. Cooper LewisJr.Jr., James G. Kereiakes & Bernard S. Aron. (1990) The modification of specific absorption rates in interstitial microwave hyperthermia via tissue-equivalent material bolus. International Journal of Radiation Oncology*Biology*Physics 19:3, pages 677-685.
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M.W. DeWhirst, T.L. Phillips, T.V. Samulski, P. Stauffer, P. Shrivastava, B. Paliwal, T. Pajak, M. Gillim, M. Sapozink, R. Myerson, F.M. Waterman, S.A. Sapareto, P. Corry, T.C. Cetas, D.B. Leeper, P. Fessenden, D. Kapp, J.R. Oleson & B. Emami. (1990) RTOG quality assurance guidelines for clinical trials using hyperthermia. International Journal of Radiation Oncology*Biology*Physics 18:5, pages 1249-1259.
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Luther W. Brady, Arnold M. Markoe, Bizhan Micaily, Scot A. Fisher & Frank R. Lamm. (1990) Innovative techniques in radiation oncology.Clinical research programs to improve local and regional control in cancer. Cancer 65:S3, pages 610-624.
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T. V. Samulski & P. Fessenden. 1990. Methods of Hyperthermia Control. Methods of Hyperthermia Control 1 34 .
J. Alexander Marchosky, Charles F. Babbs, Christopher J. Moran, Neal E. Fearnot, John A. DeFord & Deborah M. Welsh. 1990. Consensus on Hyperthermia for the 1990s. Consensus on Hyperthermia for the 1990s 129 143 .
Mark W. Dewhirst. (1989) Animal Modeling and Thermal Dose. Radiologic Clinics of North America 27:3, pages 509-518.
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Fred W. Hetzel. (1989) Biologic Rationale for Hyperthermia. Radiologic Clinics of North America 27:3, pages 499-508.
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Jens Overgaard. (1989) The current and potential role of hyperthermia in radiotherapy. International Journal of Radiation Oncology*Biology*Physics 16:3, pages 535-549.
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J.L. Meyer, D.S. Kapp, P. Fessenden & G.H. Hahn. (1989) Hyperthermic oncology: Current biology physics and clinical results. Pharmacology & Therapeutics 42:2, pages 251-288.
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Mark W. Dewhirst. 1989. Cancer Management in Man. Cancer Management in Man 159 164 .
T.L. Borok, A. Winter, J. Laing, R. Paglione, F. Sterzer, I. Sinclair & J. Plafker. (1988) Microwave Hyperthermia Radiosensitized Iridium-192 for Recurrent Brain Malignancy. Medical Dosimetry 13:1, pages 29-36.
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Edward L. Gillette, Sharon L. McChesney, Mark W. Dewhirst & Robert J. Scott. (1987) Response of canine oral carcinomas to heat and radiation. International Journal of Radiation Oncology*Biology*Physics 13:12, pages 1861-1867.
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