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Original Article

Alteration in the hypoxic fraction of quiescent cell populations by hyperthermia at mild temperatures

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Pages 401-411 | Received 06 Jan 1997, Accepted 13 Mar 1997, Published online: 09 Jul 2009

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Shin-ichiro Masunaga, Yoshinori Sakurai, Hiroki Tanaka, Takushi Takata, Minoru Suzuki, Yu Sanada, Keizo Tano, Akira Maruhashi & Koji Ono. (2019) Usefulness of combination with both continuous administration of hypoxic cytotoxin and mild temperature hyperthermia in boron neutron capture therapy in terms of local tumor response and lung metastatic potential. International Journal of Radiation Biology 95:12, pages 1708-1717.
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Shin-Ichiro Masunaga, Yong Liu, Yoshinori Sakurai, Hiroki Tanaka, Minoru Suzuki, Natsuko Kondo, Akira Maruhashi & Koji Ono. (2012) Usefulness of combined treatment with continuous administration of tirapazamine and mild temperature hyperthermia in γ-ray irradiation in terms of local tumour response and lung metastatic potential. International Journal of Hyperthermia 28:7, pages 636-644.
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Articles from other publishers (13)

Shin-ichiro Masunaga, Yu Sanada, Keizo Tano, Yoshinori Sakurai, Hiroki Tanaka, Takushi Takata, Minoru Suzuki & Koji Ono. (2020) An attempt to improve the therapeutic effect of boron neutron capture therapy using commonly employed 10B-carriers based on analytical studies on the correlation among quiescent tumor cell characteristics, tumor heterogeneity and cancer stemness. Journal of Radiation Research 61:6, pages 876-885.
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SHIN-ICHIRO MASUNAGA, YOSHINORI SAKURAI, KEIZO TANO, HIROKI TANAKA, MINORU SUZUKI, NATSUKO KONDO, MASARU NARABAYASHI, TSUBASA WATANABE, YOSUKE NAKAGAWA, AKIRA MARUHASHI & KOJI ONO. (2014) Effect of bevacizumab combined with boron neutron capture therapy on local tumor response and lung metastasis. Experimental and Therapeutic Medicine 8:1, pages 291-301.
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S Masunaga, Y Sakurai, H Tanaka, M Suzuki, Y Liu, N Kondo, A Maruhashi, Y Kinashi & K Ono. (2012) Effects of employing a 10 B-carrier and manipulating intratumour hypoxia on local tumour response and lung metastatic potential in boron neutron capture therapy . The British Journal of Radiology 85:1011, pages 249-258.
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S Masunaga, Y Liu, H Tanaka, Y Sakurai, M Suzuki, N Kondo, A Maruhashi & K Ono. (2011) Reducing intratumour acute hypoxia through bevacizumab treatment, referring to the response of quiescent tumour cells and metastatic potential. The British Journal of Radiology 84:1008, pages 1131-1138.
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S Masunaga, Y Matsumoto, G Kashino, R Hirayama, Y Liu, H Tanaka, Y Sakurai, M Suzuki, Y Kinashi, A Maruhashi & K Ono. (2010) Significance of manipulating tumour hypoxia and radiation dose rate in terms of local tumour response and lung metastatic potential, referring to the response of quiescent cell populations. The British Journal of Radiology 83:993, pages 776-784.
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Shin-ichiro Masunaga, Ryoichi Hirayama, Akiko Uzawa, Genro Kashino, Takushi Takata, Hiroki Tanaka, Minoru Suzuki, Yuko Kinashi, Yong Liu, Sachiko Koike, Koichi Ando & Koji Ono. (2010) Influence of manipulating hypoxia in solid tumors on the radiation dose-rate effect in vivo, with reference to that in the quiescent cell population. Japanese Journal of Radiology 28:2, pages 132-142.
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Shin-ichiro Masunaga, Yoshitaka Matsumoto, Ryoichi Hirayama, Genro Kashino, Hiroki Tanaka, Minoru Suzuki, Yuko Kinashi, Yong Liu, Koichi Ando & Koji Ono. (2009) Significance of manipulating intratumor hypoxia in the effect on lung metastases in radiotherapy, with reference to its effect on the sensitivity of intratumor quiescent cells. Clinical & Experimental Metastasis 26:7, pages 693-700.
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SHIN-ICHIRO MASUNAGA, YASUMASA NISHIMURA, MASAHIRO HIRAOKA, MITSUYUKI ABE, MASAJI TAKAHASHI & KOJI ONO. (2007) Efficacy of Mild Temperature Hyperthermia in Combined Treatments for Cancer Therapy癌治療における併用療法としての低温度温熱処置の有用性について. Thermal Medicine 23:3, pages 103-112.
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Shin-ichiro Masunaga, Akihisa Takahashi, Ken Ohnishi, Takeo Ohnishi, Kenji Nagata, Minoru Suzuki, Yuko Kinashi & Koji Ono. (2004) Effects of mild temperature hyperthermia and p53 status on the size of hypoxic fractions in solid tumors, with reference to the effect in intratumor quiescent cell populations. International Journal of Radiation Oncology*Biology*Physics 60:2, pages 570-577.
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Shin‐ichiro Masunaga, Koji Ono, Akihisa Takahashi, Ken Ohnishi, Takeo Ohnishi, Minoru Suzuki, Kenji Nagata, Yuko Kinashi, Hideko Nagasawa, Yoshihiro Uto & Hitoshi Hori. (2005) Usefulness of combined treatment with mild temperature hyperthermia and/or tirapazamine in the treatment of solid tumors: its independence of p53 status. Cancer Science 94:1, pages 125-133.
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SHIN-ICHIRO MASUNAGA & KOJI ONO. (2002) Significance of the Response of Quiescent Cell Populations within Solid Tumors in Cancer Therapy. Journal of Radiation Research 43:1, pages 11-11.
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Anke Ressel, Christoph Weiss & Thomas Feyerabend. (2001) Tumor oxygenation after radiotherapy, chemotherapy, and/or hyperthermia predicts tumor free survival. International Journal of Radiation Oncology*Biology*Physics 49:4, pages 1119-1125.
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Shin‐ichiro Masunaga, Koji Ono, Minoru Suzuki, Yuko Kinashi, Masao Takagaki, Hitoshi Hori, Soko Kasai, Hideko Nagasawa & Yoshihiro Uto. (2005) Usefulness of Tirapazamine as a Combined Agent in Chemoradiation and Thermo‐chemoradiation Therapy at Mild Temperatures: Reference to the Effect on Intratumor Quiescent Cells. Japanese Journal of Cancer Research 91:5, pages 566-572.
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