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Original Article

Enhancement of Vitamin D Metabolites in the Eye Following Vitamin D3 Supplementation and UV-B Irradiation

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Pages 871-878 | Received 06 Jan 2012, Accepted 22 Apr 2012, Published online: 25 May 2012

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (2)

Xiaowen Lu, Zhong Chen & Mitchell A. Watsky. (2021) Effects of 1,25 and 24,25 Vitamin D on Corneal Fibroblast VDR and Vitamin D Metabolizing and Catabolizing Enzymes. Current Eye Research 46:9, pages 1271-1282.
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Marcella Nebbioso, Giuseppe Buomprisco, Antonia Pascarella & Nicola Pescosolido. (2017) Modulatory effects of 1,25-dihydroxyvitamin D3 on eye disorders: A critical review. Critical Reviews in Food Science and Nutrition 57:3, pages 559-565.
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Articles from other publishers (52)

Xiaowen Lu, Zhong Chen, Jerry Lu & Mitchell A. Watsky. (2023) Effects of 1,25-Vitamin D3 and 24,25-Vitamin D3 on Corneal Nerve Regeneration in Diabetic Mice. Biomolecules 13:12, pages 1754.
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Anna Mueller, Isabel Lam, Krishna Kishor, Richard K. Lee & Sanjoy Bhattacharya. (2023) Secondary glaucoma: Toward interventions based on molecular underpinnings. WIREs Mechanisms of Disease.
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Funda Kocaay, Abdurrahman Bilen, Abdulvahit Asik, Şerife Şule Çınar, Emre Aydemir, Gözde Aksoy Aydemir, Ali Karnaz & Veysel Cankurtaran. (2023) Changes in choroidal tissue post-supplementation with vitamin D in pediatric patients who are deficient in vitamin D. International Ophthalmology 43:10, pages 3767-3775.
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Xiaowen Lu, Zhong Chen, Jerry Lu & Mitchell Watsky. (2023) Effects of Topical 1,25 and 24,25 Vitamin D on Diabetic, Vitamin D Deficient and Vitamin D Receptor Knockout Mouse Corneal Wound Healing. Biomolecules 13:7, pages 1065.
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Maurizio Rolando & Stefano Barabino. (2023) Dry Eye Disease: What Is the Role of Vitamin D?. International Journal of Molecular Sciences 24:2, pages 1458.
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Massimo Lorusso, Luisa Micelli Ferrari, Maria Vittoria Cicinelli, Saba Ciani & Edmondo Ceci. (2022) Study of vitamin D penetration in the human aqueous after topical administration. European Journal of Ophthalmology 32:6, pages 3693-3698.
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Sevim Ayça Seyyar, Ecem Onder Tokuc, Nesime Setge Tıskaoğlu, Veysel Levent Karabaş & Kıvanç Güngör. (2022) Do serum vitamin D levels correlate with Macular Edema or with Diabetic Retinopathy?. European Journal of Ophthalmology 32:6, pages 3592-3598.
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MarwaA Zaky, HatemM Marey, DinaG. H. Abd Elmonem & AM. S. Fayed. (2022) Effect of vitamin D on the efficacy of topical artificial tears in patients with dry-eye disease. Menoufia Medical Journal 35:2, pages 856.
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Maria Stella Valle, Cristina Russo & Lucia Malaguarnera. (2021) Protective role of vitamin D against oxidative stress in diabetic retinopathy. Diabetes/Metabolism Research and Reviews 37:8.
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Li Lu, Gaocheng Zou, Li Chen, Qianyi Lu, Mian Wu & Chunxia Li. (2021) Elevated NLRP3 Inflammasome Levels Correlate With Vitamin D in the Vitreous of Proliferative Diabetic Retinopathy. Frontiers in Medicine 8.
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Şemsettin Bilak, Sedat Yılmaz & Burak Bilgin. (2021) Comparison of vitamin D levels between patients with pterygium and healthy subjects. International Ophthalmology 41:9, pages 3057-3064.
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Brandon Huynh, Peter Shah, Freda Sii, Damien Hunter, Nicole Carnt & Andrew White. (2021) Low systemic vitamin D as a potential risk factor in primary open-angle glaucoma: a review of current evidence. British Journal of Ophthalmology 105:5, pages 595-601.
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Sayena Jabbehdari, Ghasem Yazdanpanah, Eric Chen, Neda Afsharkhamseh, Mahmood Ghassemi, Khandaker N. Anwar, Cheryl Fonteh, Ali R. Djalilian & Kai B. Kang. (2021) Dose-dependent therapeutic effects of topical 1,25 OH-vitamin D3 on corneal wound healing. Molecular Biology Reports 48:5, pages 4083-4091.
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Laura D Carbone, Karen Johnson, Joseph C Larson, Fridtjof Thomas, Jean Wactawski-Wende, Kathryn Bollinger, Zhao Chen & Mitchell Watsky. (2021) Association of vitamin D with incident glaucoma: findings from the Women’s Health Initiative. Journal of Investigative Medicine 69:4, pages 843-850.
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Nurgül Örnek, Tevfik Oğurel & Üçler Kısa. (2021) Tear Fluid and Serum Vitamin D Concentrations in Unilateral Pterygium. Optometry and Vision Science 98:2, pages 170-174.
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Jada Morris, Ciara Myer, Tara Cornet, Anna K. Junk, Richard K. Lee & Sanjoy K. Bhattacharya. 2021. Proteomics and Systems Biology. Proteomics and Systems Biology 271 290 .
Hasan Öncül, Mehmet Fuat Alakus, Mehtap Çağlayan, Fatma Yılmaz Öncül, Umut Dag & Esref Arac. (2020) Changes in choroidal thickness after vitamin D supplementation in patients with vitamin D deficiency. Canadian Journal of Ophthalmology 55:6, pages 486-491.
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Hana Abouzeid & Caroline Flora Samer. (2020) Vitamin D and Glaucoma: A Critical Review of the Literature. Journal of Ophthalmology 2020, pages 1-8.
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Ciara Myer, Leila Abdelrahman, Santanu Banerjee, Ram B. Khattri, Matthew E. Merritt, Anna K. Junk, Richard K. Lee & Sanjoy K. Bhattacharya. (2020) Aqueous humor metabolite profile of pseudoexfoliation glaucoma is distinctive. Molecular Omics 16:5, pages 425-435.
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Patricia Fernandez-Robredo, Jorge González-Zamora, Sergio Recalde, Valentina Bilbao-Malavé, Jaione Bezunartea, Maria Hernandez & Alfredo Garcia-Layana. (2020) Vitamin D Protects against Oxidative Stress and Inflammation in Human Retinal Cells. Antioxidants 9:9, pages 838.
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Claire Vergneau-Grosset & Franck Péron. (2020) Effect of ultraviolet radiation on vertebrate animals: update from ethological and medical perspectives. Photochemical & Photobiological Sciences 19:6, pages 752-762.
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Xiaowen Lu, Sarah Vick, Zhong Chen, Jie Chen & Mitchell A. Watsky. (2020) Effects of Vitamin D Receptor Knockout and Vitamin D Deficiency on Corneal Epithelial Wound Healing and Nerve Density in Diabetic Mice. Diabetes 69:5, pages 1042-1051.
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Tolga Kocaturk, Sinan Bekmez & Mustafa Unubol. (2019) Effects of vitamin D deficiency on intraocular pressure values obtained by ocular response analyzer. International Ophthalmology 40:3, pages 697-701.
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Xiaowen Lu & Mitchell A. Watsky. (2019) Influence of Vitamin D on Corneal Epithelial Cell Desmosomes and Hemidesmosomes. Investigative Opthalmology & Visual Science 60:13, pages 4074.
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Xiaowen Lu, Zhong Chen, Sarah Vick & Mitchell A. Watsky. (2019) Vitamin D receptor and metabolite effects on corneal epithelial cell gap junction proteins. Experimental Eye Research 187, pages 107776.
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Kyoung Lae Kim, Su Young Moon, Hye-Mi Noh, Sung Pyo Park & Yong-Kyu Kim. (2019) Serum and aqueous humor vitamin D levels in patients with diabetic macular edema. Graefe's Archive for Clinical and Experimental Ophthalmology 257:6, pages 1191-1198.
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Yu Tsun Lai, Renato Galão Cerquinho, Matheus Moreira Perez, Beatriz da Costa Aguiar Alves, Edimar Cristiano Pereira, Ligia Ajaime Azzalis, Virginia Berlanga Campos Junqueira, Lismeia Raimundo Soares & Fernando Luiz Affonso Fonseca. (2019) Determination of vitamin D in tears of healthy individuals by the electrochemiluminescence method. Journal of Clinical Laboratory Analysis 33:4.
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Archit Kumar, Mini P. Singh, Tripti Rungta, Ajay Patial, Savita Verma Attri, Bikash Medhi & Radha Kanta Ratho. (2018) Ocular Pharmacokinetics of 25-Hydroxyvitamin D3 After Weekly Supplementation in Rabbits Using Ultra Performance Liquid Chromatography–Tandem Mass Spectrometer. European Journal of Drug Metabolism and Pharmacokinetics 43:5, pages 607-613.
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Goktug Demirci, Sevil Karaman Erdur, Mustafa Ozsutcu, Mustafa Eliacik, Oktay Olmuscelik, Rukiye Aydin & Mehmet Selim Kocabora. (2018) Dry Eye Assessment in Patients With Vitamin D Deficiency. Eye & Contact Lens: Science & Clinical Practice 44:1, pages S62-S65.
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M. Notara, S. Behboudifard, M. A. Kluth, C. Maßlo, C. Ganss, M. H. Frank, B. Schumacher & C. Cursiefen. (2018) UV light-blocking contact lenses protect against short-term UVB-induced limbal stem cell niche damage and inflammation. Scientific Reports 8:1.
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Swaminathan Sethu, Rohit Shetty, Kalyani Deshpande, Natasha Pahuja, Nandini Chinnappaiah, Aarti Agarwal, Anupam Sharma & Arkasubhra Ghosh. (2016) Correlation between tear fluid and serum vitamin D levels. Eye and Vision 3:1.
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Saadettin Sel, Stefanie Trau, Friedrich Paulsen, Thomas Kalinski, Gabriele I. Stangl & Norbert Nass. (2016) 1,25-dihydroxyvitamin D3 inhibits corneal wound healing in an ex-vivo mouse model. Graefe's Archive for Clinical and Experimental Ophthalmology 254:4, pages 717-724.
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Rose Y. Reins & Alison M. McDermott. (2015) Vitamin D: Implications for ocular disease and therapeutic potential. Experimental Eye Research 134, pages 101-110.
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Yao Jin, Chen Xi, Jiang Qin, Victor R. Preedy & Ji Yong. 2014. Handbook of Nutrition, Diet and the Eye. Handbook of Nutrition, Diet and the Eye 339 348 .
Isabelle Jalbert. (2013) Diet, nutraceuticals and the tear film. Experimental Eye Research 117, pages 138-146.
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Eric L. Singman, David Poon & Albert S. Jun. (2013) Putative Corneal Neuralgia Responding to Vitamin D Supplementation. Case Reports in Ophthalmology 4:3, pages 105-108.
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