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Yannick Parmentier, Corinne Pothier, Nicola Hewitt, Ludwig Vincent, Fabrice Caradec, Jia Liu, Feifei Lin, Marie-Michèle Trancart, Fabrice Guillet, Belkacem Bouaita, Christophe Chesne & Bernard Walther. (2019) Direct and quantitative evaluation of the major human CYP contribution (fmCYP) to drug clearance using the in vitro Silensomes™ model. Xenobiotica 49:1, pages 22-35.
Read now
Read now
Wei Liu, Hongming Liu, Hua Sun, Dong Dong, Zhiguo Ma, Yifei Wang & Baojian Wu. (2014) Metabolite elucidation of the Hsp90 inhibitor SNX-2112 using ultraperformance liquid chromatography/quadrupole time-of-flight mass spectrometry (UPLC-QTOF/MS). Xenobiotica 44:5, pages 455-464.
Read now
Read now
Li Di. (2014) The role of drug metabolizing enzymes in clearance. Expert Opinion on Drug Metabolism & Toxicology 10:3, pages 379-393.
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Articles from other publishers (31)
Ziru Dai, Yue Wu, Yuan Xiong, Jingjing Wu, Min Wang, Xiao Sun, Xinxin Ding, Ling Yang, Xiaobo Sun & Guangbo Ge. (2023) CYP1A inhibitors: Recent progress, current challenges, and future perspectives. Medicinal Research Reviews 44:1, pages 169-234.
Crossref
Crossref
Li Di. (2023) Quantitative Translation of Substrate Intrinsic Clearance from Recombinant CYP1A1 to Humans. The AAPS Journal 25:6.
Crossref
Crossref
Chiratidzo R. Chamboko, Wayde Veldman, Rolland Bantar Tata, Birgit Schoeberl & Özlem Tastan Bishop. (2023) Human Cytochrome P450 1, 2, 3 Families as Pharmacogenes with Emphases on Their Antimalarial and Antituberculosis Drugs and Prevalent African Alleles. International Journal of Molecular Sciences 24:4, pages 3383.
Crossref
Crossref
Haiyan Li, Yang Sheng, Wei Li & Lin Yuan. (2022) Recent Advances in Molecular Fluorescent Probes for CYP450 Sensing and Imaging. Chemosensors 10:8, pages 304.
Crossref
Crossref
Hyejin Park, Rahul Brahma, Jae‐Min Shin & Kwang‐Hwi Cho. (2021)
Prediction of human cytochrome
P450
inhibition using bio‐selectivity induced deep neural network
. Bulletin of the Korean Chemical Society 43:2, pages 261-269.
Crossref
Crossref
Usman Ali Ashfaq, Farah Shahid & Samman Munir. 2022. Biochemistry of Drug Metabolizing Enzymes. Biochemistry of Drug Metabolizing Enzymes
29
72
.
Yuanqiang Sun, Pengjuan Sun & Wei Guo. (2021) Fluorescent probes for iron, heme, and related enzymes. Coordination Chemistry Reviews 429, pages 213645.
Crossref
Crossref
Jingjing Wu, Xiaoqing Guan, Ziru Dai, Rongjing He, Xinxin Ding, Ling Yang & Guangbo Ge. (2021) Molecular probes for human cytochrome P450 enzymes: Recent progress and future perspectives. Coordination Chemistry Reviews 427, pages 213600.
Crossref
Crossref
Feng Zhang, Jian Huang, Rong-Jing He, Lu Wang, Peng-Chao Huo, Xiao-Qing Guan, Sheng-Quan Fang, Yan-Wei Xiang, Shou-Ning Jia & Guang-Bo Ge. (2020) Herb-drug interaction between Styrax and warfarin: Molecular basis and mechanism. Phytomedicine 77, pages 153287.
Crossref
Crossref
Hiroaki Edamatsu, Masataka Yagawa, Shinichi Ikushiro, Toshiyuki Sakaki, Yoshiaki Nakagawa, Hisashi Miyagawa & Miki Akamatsu. (2020) Identification and in silico prediction of metabolites of tebufenozide derivatives by major human cytochrome P450 isoforms. Bioorganic & Medicinal Chemistry 28:9, pages 115429.
Crossref
Crossref
Alexander V. Dmitriev, Alexey A. Lagunin, Dmitry А. Karasev, Anastasia V. Rudik, Pavel V. Pogodin, Dmitry A. Filimonov & Vladimir V. Poroikov. (2019) Prediction of Drug-Drug Interactions Related to Inhibition or Induction of Drug-Metabolizing Enzymes. Current Topics in Medicinal Chemistry 19:5, pages 319-336.
Crossref
Crossref
Junji Zhang, Xianzhi Chai, Xiao-Peng He, Hae-Jo Kim, Juyoung Yoon & He Tian. (2019) Fluorogenic probes for disease-relevant enzymes. Chemical Society Reviews 48:2, pages 683-722.
Crossref
Crossref
Chun-Zhi Ai, Hui-Zi Man, Yasmeen Saeed, Du-Chu Chen, Li-Hua Wang & Yi-Zhou Jiang. (2019) Computational insight into crucial binding features for metabolic specificity of cytochrome P450 17A1. Informatics in Medicine Unlocked 15, pages 100172.
Crossref
Crossref
Hong-Wen Liu, Lanlan Chen, Chengyan Xu, Zhe Li, Haiyang Zhang, Xiao-Bing Zhang & Weihong Tan. (2018) Recent progresses in small-molecule enzymatic fluorescent probes for cancer imaging. Chemical Society Reviews 47:18, pages 7140-7180.
Crossref
Crossref
Zi-Ru Dai, Lei Feng, Qiang Jin, Hailing Cheng, Yan Li, Jing Ning, Yang Yu, Guang-Bo Ge, Jing-Nan Cui & Ling Yang. (2017) A practical strategy to design and develop an isoform-specific fluorescent probe for a target enzyme: CYP1A1 as a case study. Chemical Science 8:4, pages 2795-2803.
Crossref
Crossref
R.E. White. 2017. Comprehensive Medicinal Chemistry III. Comprehensive Medicinal Chemistry III
1
33
.
Roger Stacke Ferreira, Cíntia da Cruz Chivittz, Guilherme Senna dos Santos & Juliano Zanette. (2016) Cytochrome P450 1A mRNA in the guppy Phalloceros caudimaculatus and response to beta-naphthoflavone and environmental samples. Aquatic Toxicology 181, pages 86-93.
Crossref
Crossref
S. M. M. Nakayama, Y. Ikenaka, A. Hayami, H. Mizukawa, W. S. Darwish, K. P. Watanabe, Y. K. Kawai & M. Ishizuka. (2016) Characterization of equine cytochrome P450: role of CYP3A in the metabolism of diazepam. Journal of Veterinary Pharmacology and Therapeutics 39:5, pages 478-487.
Crossref
Crossref
X. Yang, K. Atkinson & L. Di. (2015) Novel Cytochrome P450 Reaction Phenotyping for Low-Clearance Compounds Using the Hepatocyte Relay Method. Drug Metabolism and Disposition 44:3, pages 460-465.
Crossref
Crossref
Jing-Jing Wu, Guang-Bo Ge, Yu-Qi He, Ping Wang, Zi-Ru Dai, Jing Ning, Liang-Hai Hu & Ling Yang. (2015) Gomisin A is a Novel Isoform-Specific Probe for the Selective Sensing of Human Cytochrome P450 3A4 in Liver Microsomes and Living Cells. The AAPS Journal 18:1, pages 134-145.
Crossref
Crossref
Li Di & Edward H. Kerns. 2016. Drug-Like Properties. Drug-Like Properties
161
194
.
Zi-Ru Dai, Guang-Bo Ge, Lei Feng, Jing Ning, Liang-Hai Hu, Qiang Jin, Dan-Dan Wang, Xia Lv, Tong-Yi Dou, Jing-Nan Cui & Ling Yang. (2015) A Highly Selective Ratiometric Two-Photon Fluorescent Probe for Human Cytochrome P450 1A. Journal of the American Chemical Society 137:45, pages 14488-14495.
Crossref
Crossref
Naoki Shirotani, Moe Togawa, Shinichi Ikushiro, Toshiyuki Sakaki, Toshiyuki Harada, Hisashi Miyagawa, Masayoshi Matsui, Hirohisa Nagahori, Kazuki Mikata, Kazuhiko Nishioka, Nobuhiro Hirai & Miki Akamatsu. (2015) Identification and in silico prediction of metabolites of the model compound, tebufenozide by human CYP3A4 and CYP2C19. Bioorganic & Medicinal Chemistry 23:20, pages 6594-6601.
Crossref
Crossref
Zi-Ru Dai, Chun-Zhi Ai, Guang-Bo Ge, Yu-Qi He, Jing-Jing Wu, Jia-Yue Wang, Hui-Zi Man, Yan Jia & Ling Yang. (2015) A Mechanism-Based Model for the Prediction of the Metabolic Sites of Steroids Mediated by Cytochrome P450 3A4. International Journal of Molecular Sciences 16:12, pages 14677-14694.
Crossref
Crossref
Hannu Raunio, Mira Kuusisto, Risto O. Juvonen & Olli T. Pentikäinen. (2015) Modeling of interactions between xenobiotics and cytochrome P450 (CYP) enzymes. Frontiers in Pharmacology 6.
Crossref
Crossref
Lars Olsen, Chris Oostenbrink & Flemming Steen Jørgensen. (2015) Prediction of cytochrome P450 mediated metabolism. Advanced Drug Delivery Reviews 86, pages 61-71.
Crossref
Crossref
Csilla Hegedüs, Tamás Hegedüs & Balázs Sarkadi. 2015. Resistance to Targeted ABC Transporters in Cancer. Resistance to Targeted ABC Transporters in Cancer
209
244
.
Tobias Schmidt, Andreas Bergner & Torsten Schwede. (2014) Modelling three-dimensional protein structures for applications in drug design. Drug Discovery Today 19:7, pages 890-897.
Crossref
Crossref
P. Ross Wilderman, Manish B. Shah, Hyun-Hee Jang, C. David Stout & James R. Halpert. (2013) Structural and Thermodynamic Basis of (+)-α-Pinene Binding to Human Cytochrome P450 2B6. Journal of the American Chemical Society 135:28, pages 10433-10440.
Crossref
Crossref
Laure Elens, Teun van Gelder, Dennis A Hesselink, Vincent Haufroid & Ron HN van Schaik. (2013)
CYP3A4*22
: promising newly identified
CYP3A4
variant allele for personalizing pharmacotherapy
. Pharmacogenomics 14:1, pages 47-62.
Crossref
Crossref
Baojian Wu & Dong Dong. (2012) Human cytosolic glutathione transferases: structure, function, and drug discovery. Trends in Pharmacological Sciences 33:12, pages 656-668.
Crossref
Crossref