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Lisa Chedik, Dominique Mias-Lucquin, Olivier Fardel, Olivier Delalande & Arnaud Bruyere. (2022) Interactions of organophosphorus pesticides with ATP-binding cassette (ABC) drug transporters. Xenobiotica 52:6, pages 644-652.
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Vera Silva, Eva Gil-Martins, Bárbara Silva, Carolina Rocha-Pereira, Maria Emília Sousa, Fernando Remião & Renata Silva. (2021) Xanthones as P-glycoprotein modulators and their impact on drug bioavailability. Expert Opinion on Drug Metabolism & Toxicology 17:4, pages 441-482.
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Kodye L. Abbott, Patrick C. Flannery, Kristina S. Gill, Dawn M. Boothe, Muralikrishnan Dhanasekaran, Sridhar Mani & Satyanarayana R. Pondugula. (2020) Adverse pharmacokinetic interactions between illicit substances and clinical drugs. Drug Metabolism Reviews 52:1, pages 44-65.
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Patrick E. Hanna & M. W. Anders. (2019) The mercapturic acid pathway. Critical Reviews in Toxicology 49:10, pages 819-929.
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Lisa Chedik, Arnaud Bruyere & Olivier Fardel. (2019) Interactions of organophosphorus pesticides with solute carrier (SLC) drug transporters. Xenobiotica 49:3, pages 363-374.
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Martyn Howard, Jill Barber, Naved Alizai & Amin Rostami-Hodjegan. (2018) Dose adjustment in orphan disease populations: the quest to fulfill the requirements of physiologically based pharmacokinetics. Expert Opinion on Drug Metabolism & Toxicology 14:12, pages 1315-1330.
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Lisa Chedik, Arnaud Bruyere, Astrid Bacle, Sophie Potin, Marc Le Vée & Olivier Fardel. (2018) Interactions of pesticides with membrane drug transporters: implications for toxicokinetics and toxicity. Expert Opinion on Drug Metabolism & Toxicology 14:7, pages 739-752.
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Gary Ginsberg, Suryanarayana V Vulimiri, Yu-Sheng Lin, Jayaram Kancherla, Brenda Foos & Babasaheb Sonawane. (2017) A framework and case studies for evaluation of enzyme ontogeny in children’s health risk evaluation. Journal of Toxicology and Environmental Health, Part A 80:10-12, pages 569-593.
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David E. Amacher. (2016) The regulation of human hepatic drug transporter expression by activation of xenobiotic-sensing nuclear receptors. Expert Opinion on Drug Metabolism & Toxicology 12:12, pages 1463-1477.
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Articles from other publishers (66)
Matthew E. Michel, Christopher C. Wen, Sook Wah Yee, Kathleen M. Giacomini, Amro Hamdoun & Sascha C. T. Nicklisch. (2023)
TICBase
: Integrated Resource for Data on Drug and Environmental Chemical Interactions with Mammalian Drug Transporters
. Clinical Pharmacology & Therapeutics 114:6, pages 1293-1303.
Crossref
Crossref
Jéssica Veiga-Matos, Ana I. Morales, Marta Prieto, Fernando Remião & Renata Silva. (2023) Study Models of Drug–Drug Interactions Involving P-Glycoprotein: The Potential Benefit of P-Glycoprotein Modulation at the Kidney and Intestinal Levels. Molecules 28:22, pages 7532.
Crossref
Crossref
Songhui Kim, Masahiro Fukuda, Jung Yeol Lee, Young-Tae Chang, H. Shawn Je & Beomsue Kim. (2023) Distinctive Labeling of Live Monocytes and Neutrophils with a Single Fluorescent Molecule. Chemosensors 11:5, pages 265.
Crossref
Crossref
Cristian Sandoval, Yolanda Calle, Karina Godoy & Jorge Farías. (2023) An Updated Overview of the Role of CYP450 during Xenobiotic Metabolization in Regulating the Acute Myeloid Leukemia Microenvironment. International Journal of Molecular Sciences 24:7, pages 6031.
Crossref
Crossref
Csilla Özvegy-Laczka, Orsolya Ungvári & Éva Bakos. (2023) Fluorescence-based methods for studying activity and drug-drug interactions of hepatic solute carrier and ATP binding cassette proteins involved in ADME-Tox. Biochemical Pharmacology 209, pages 115448.
Crossref
Crossref
Deepika Deepika & Vikas Kumar. (2023) The Role of “Physiologically Based Pharmacokinetic Model (PBPK)” New Approach Methodology (NAM) in Pharmaceuticals and Environmental Chemical Risk Assessment. International Journal of Environmental Research and Public Health 20:4, pages 3473.
Crossref
Crossref
Omnia Azmy Nabeh. (2022) Gut microbiota and cardiac arrhythmia: a pharmacokinetic scope. The Egyptian Heart Journal 74:1.
Crossref
Crossref
D. De Panis, H. Dopazo, E. Bongcam-Rudloff, A. Conesa & E. Hasson. (2022) Transcriptional responses are oriented towards different components of the rearing environment in two Drosophila sibling species. BMC Genomics 23:1.
Crossref
Crossref
Joe Jongpyo Lim, Youjun Suh, Elaine M. Faustman & Julia Yue Cui. (2022) Perfluorinated Carboxylic Acids with Increasing Carbon Chain Lengths Upregulate Amino Acid Transporters and Modulate Compensatory Response of Xenobiotic Transporters in HepaRG Cells. Drug Metabolism and Disposition 50:10, pages 1396-1413.
Crossref
Crossref
Carolina I. Ghanem & Jose E. Manautou. (2022) Role and Regulation of Hepatobiliary ATP-Binding Cassette Transporters during Chemical-Induced Liver Injury. Drug Metabolism and Disposition 50:10, pages 1376-1388.
Crossref
Crossref
Agnieszka Potęga. (2022) Glutathione-Mediated Conjugation of Anticancer Drugs: An Overview of Reaction Mechanisms and Biological Significance for Drug Detoxification and Bioactivation. Molecules 27:16, pages 5252.
Crossref
Crossref
Chukwunonso K. Nwabufo. (2022) Relevance of ABC Transporters in Drug Development. Current Drug Metabolism 23:6, pages 434-446.
Crossref
Crossref
Sepideh Mirzaei, Mohammad Hossein Gholami, Farid Hashemi, Amirhossein Zabolian, Mahdi Vasheghani Farahani, Kiavash Hushmandi, Ali Zarrabi, Aaron Goldman, Milad Ashrafizadeh & Gorka Orive. (2022) Advances in understanding the role of P-gp in doxorubicin resistance: Molecular pathways, therapeutic strategies, and prospects. Drug Discovery Today 27:2, pages 436-455.
Crossref
Crossref
Nicholas J. Hunt, Peter A. G. McCourt, Zdenka Kuncic, David G. Le Couteur & Victoria C. Cogger. (2022) Opportunities and Challenges for Nanotherapeutics for the Aging Population. Frontiers in Nanotechnology 4.
Crossref
Crossref
Suzeeta Bhandari, Kirpal S. Bisht & David J. Merkler. (2022) The Biosynthesis and Metabolism of the N-Acylated Aromatic Amino Acids: N-Acylphenylalanine, N-Acyltyrosine, N-Acyltryptophan, and N-Acylhistidine. Frontiers in Molecular Biosciences 8.
Crossref
Crossref
Jean-François Ghersi-Egea, Nathalie Strazielle & Xavier Declèves. 2022. Drug Delivery to the Brain. Drug Delivery to the Brain
141
169
.
Alan Talevi & Carolina L. Bellera. 2022. The ADME Encyclopedia. The ADME Encyclopedia
101
107
.
Alan Talevi & Carolina L. Bellera. 2022. The ADME Encyclopedia. The ADME Encyclopedia
958
965
.
Anne‐Margarethe Enge, Florian Kaltner, Christoph Gottschalk, Angelina Kin, Michael Kirstgen, Joachim Geyer, Anja These, Helen Hammer, Oliver Pötz, Albert Braeuning & Stefanie Hessel‐Pras. (2021)
Organic Cation Transporter I and Na
+
/taurocholate Co‐Transporting Polypeptide are Involved in Retrorsine‐ and Senecionine‐Induced Hepatotoxicity in HepaRG cells
. Molecular Nutrition & Food Research 66:2.
Crossref
Crossref
Kenza Abouir, Caroline F Samer, Yvonne Gloor, Jules A Desmeules & Youssef Daali. (2021) Reviewing Data Integrated for PBPK Model Development to Predict Metabolic Drug-Drug Interactions: Shifting Perspectives and Emerging Trends. Frontiers in Pharmacology 12.
Crossref
Crossref
João Paulo Almirão de Jesus, Letícia Cristina Assis, Alexandre Alves de Castro, Elaine Fontes Ferreira da Cunha, Eugenie Nepovimova, Kamil Kuca, Teodorico de Castro Ramalho & Felipe de Almeida La Porta. (2021) Effect of drug metabolism in the treatment of SARS-CoV-2 from an entirely computational perspective. Scientific Reports 11:1.
Crossref
Crossref
Yixin Zhao, Li Yin, Feilong Dong, Weini Zhang & Fengxiao Hu. (2021) Effects of tris (2-chloroethyl) phosphate (TCEP) on survival, growth, histological changes and gene expressions in juvenile yellow catfish Pelteobagrus fulvidraco. Environmental Toxicology and Pharmacology 87, pages 103699.
Crossref
Crossref
Eman El‐Khateeb, Adam S. Darwich, Brahim Achour, Varinder Athwal & Amin Rostami‐Hodjegan. (2021) Review article: time to revisit Child‐Pugh score as the basis for predicting drug clearance in hepatic impairment. Alimentary Pharmacology & Therapeutics 54:4, pages 388-401.
Crossref
Crossref
Francisco Esteves, José Rueff & Michel Kranendonk. (2021) The Central Role of Cytochrome P450 in Xenobiotic Metabolism—A Brief Review on a Fascinating Enzyme Family. Journal of Xenobiotics 11:3, pages 94-114.
Crossref
Crossref
Anne-Margarethe Enge, Florian Kaltner, Christoph Gottschalk, Albert Braeuning & Stefanie Hessel-Pras. (2021) Active Transport of Hepatotoxic Pyrrolizidine Alkaloids in HepaRG Cells. International Journal of Molecular Sciences 22:8, pages 3821.
Crossref
Crossref
M. H. Yashavarddhan, Sania Bajaj, Sandeep Kumar Shukla & Arpana Vibhuti. 2021. Environmental Microbiology and Biotechnology. Environmental Microbiology and Biotechnology
337
357
.
Alan Talevi & Carolina Bellera. 2021. The ADME Encyclopedia. The ADME Encyclopedia
1
7
.
Alan Talevi & Carolina L. Bellera. 2021. The ADME Encyclopedia. The ADME Encyclopedia
1
8
.
Beatriz Carvalho Henriques, Esther H. Yang, Diego Lapetina, Michael S. Carr, Vasyl Yavorskyy, Joshua Hague & Katherine J. Aitchison. (2020) How Can Drug Metabolism and Transporter Genetics Inform Psychotropic Prescribing?. Frontiers in Genetics 11.
Crossref
Crossref
Eva Gil-Martins, Daniel José Barbosa, Vera Silva, Fernando Remião & Renata Silva. (2020) Dysfunction of ABC transporters at the blood-brain barrier: Role in neurological disorders. Pharmacology & Therapeutics 213, pages 107554.
Crossref
Crossref
Diego L. Lapetina, Esther H. Yang, Beatriz C. Henriques & Katherine J. Aitchison. 2020. Seminars in Clinical Psychopharmacology. Seminars in Clinical Psychopharmacology
151
202
.
Danyi Lu, Mengjing Zhao, Min Chen & Baojian Wu. (2020) Circadian Clock–Controlled Drug Metabolism: Implications for Chronotherapeutics. Drug Metabolism and Disposition 48:5, pages 395-406.
Crossref
Crossref
Xiaogang Xun, Jie Cheng, Jing Wang, Yangping Li, Xu Li, Moli Li, Jiarun Lou, Yifan Kong, Zhenmin Bao & Xiaoli Hu. (2020) Solute carriers in scallop genome: Gene expansion and expression regulation after exposure to toxic dinoflagellate. Chemosphere 241, pages 124968.
Crossref
Crossref
Vimal M. Aga, Mujeeb U. Shad, Hongru Zhu & Carl Salzman. 2020. Handbook of Mental Health and Aging. Handbook of Mental Health and Aging
315
399
.
Robert H. Verkerk. 2020. Integrative and Functional Medical Nutrition Therapy. Integrative and Functional Medical Nutrition Therapy
191
203
.
Jee Eun Yoon, Kwang Yong Lee, Jin Sil Seok, Wei Nee Cheng, Hyuk Cheol Kwon, Chang Hee Jeong & Sung Gu Han. (2019) Zearalenone Induces Endoplasmic Reticulum Stress and Modulates the Expression of Phase I/II Enzymes in Human Liver Cells. Toxins 12:1, pages 2.
Crossref
Crossref
Dominique Lagadic-Gossmann, Kévin Hardonnière, Baharia Mograbi, Odile Sergent & Laurence Huc. (2019) Disturbances in H+ dynamics during environmental carcinogenesis. Biochimie 163, pages 171-183.
Crossref
Crossref
Min Kyu Kang, Heon Ju Lee & Joon Hyuk Choi. (2019) Imatinib-induced hepatitis treated by corticosteroids in a patient with metastatic gastrointestinal stromal tumor. Yeungnam University Journal of Medicine 36:2, pages 155-158.
Crossref
Crossref
Sanjay K. Nigam & Kevin T. Bush. (2019) Uraemic syndrome of chronic kidney disease: altered remote sensing and signalling. Nature Reviews Nephrology 15:5, pages 301-316.
Crossref
Crossref
Laure-Alix Clerbaux, Alicia Paini, Annie Lumen, Hanan Osman-Ponchet, Andrew P. Worth & Olivier Fardel. (2019) Membrane transporter data to support kinetically-informed chemical risk assessment using non-animal methods: Scientific and regulatory perspectives. Environment International 126, pages 659-671.
Crossref
Crossref
Eva Martins, Vera Silva, Agostinho Lemos, Andreia Palmeira, Ploenthip Puthongking, Emília Sousa, Carolina Rocha-Pereira, Carolina Ghanem, Helena Carmo, Fernando Remião & Renata Silva. (2019) Newly Synthesized Oxygenated Xanthones as Potential P-Glycoprotein Activators: In Vitro, Ex Vivo, and In Silico Studies. Molecules 24:4, pages 707.
Crossref
Crossref
William S. Baldwin. (2019) Phase 0 of the Xenobiotic Response: Nuclear Receptors and Other Transcription Factors As a First Step in Protection from Xenobiotics. Nuclear Receptor Research 6.
Crossref
Crossref
Robert L. Smith, Samuel M. Cohen, Shoji Fukushima, Nigel J. Gooderham, Stephen S. Hecht, F. Peter Guengerich, Ivonne M. C. M. Rietjens, Maria Bastaki, Christie L. Harman, Margaret M. McGowen & Sean V. Taylor. (2018) The safety evaluation of food flavouring substances: the role of metabolic studies. Toxicology Research 7:4, pages 618-646.
Crossref
Crossref
Jiří Vrba, Barbora Papoušková, Lenka Roubalová, Martina Zatloukalová, David Biedermann, Vladimír Křen, Kateřina Valentová, Jitka Ulrichová & Jan Vacek. (2018) Metabolism of flavonolignans in human hepatocytes. Journal of Pharmaceutical and Biomedical Analysis 152, pages 94-101.
Crossref
Crossref
Ana Lopes, Eva Martins, Renata Silva, Madalena Pinto, Fernando Remião, Emília Sousa & Carla Fernandes. (2018) Chiral Thioxanthones as Modulators of P-glycoprotein: Synthesis and Enantioselectivity Studies. Molecules 23:3, pages 626.
Crossref
Crossref
K.K. Wolf & M.F. Paine. 2018. Comprehensive Toxicology. Comprehensive Toxicology
74
98
.
Teresa Anita Mulaikal & Jean C. Emond. 2018. Liver Anesthesiology and Critical Care Medicine. Liver Anesthesiology and Critical Care Medicine
3
19
.
Limin Feng, Lijuan Liu, Ya Zhao & Ruizhi Zhao. (2017) Saikosaponins A, C and D enhance liver-targeting effects of anticancer drugs by modulating drug transporters. Oncotarget 8:66, pages 110092-110102.
Crossref
Crossref
Sabrina Nickel, Mohammed Ali Selo, Juliane Fallack, Caoimhe G. Clerkin, Hanno Huwer, Nicole Schneider-Daum, Claus-Michael Lehr & Carsten Ehrhardt. (2017) Expression and Activity of Breast Cancer Resistance Protein (BCRP/ABCG2) in Human Distal Lung Epithelial Cells In Vitro. Pharmaceutical Research 34:12, pages 2477-2487.
Crossref
Crossref
Megha Kalsi & Subba Reddy Palli. (2017) Cap n collar transcription factor regulates multiple genes coding for proteins involved in insecticide detoxification in the red flour beetle, Tribolium castaneum. Insect Biochemistry and Molecular Biology 90, pages 43-52.
Crossref
Crossref
Ramy Elgendy, Mery Giantin & Mauro Dacasto. (2017) Transcriptomic characterization of bovine primary cultured hepatocytes; a cross-comparison with a bovine liver and the Madin-Darby bovine kidney cells. Research in Veterinary Science 113, pages 40-49.
Crossref
Crossref
Sascha C.T. Nicklisch, Lindsay T. Bonito, Stuart Sandin & Amro Hamdoun. (2017) Geographic Differences in Persistent Organic Pollutant Levels of Yellowfin Tuna. Environmental Health Perspectives 125:6.
Crossref
Crossref
Jianhai Wang, Keqiu Li, Xiaoning Zhang, Dahong Teng, Mingyan Ju, Yaqing Jing, Yuxia Zhao & Guang Li. (2017) The correlation between the expression of genes involved in drug metabolism and the blood level of tacrolimus in liver transplant receipts. Scientific Reports 7:1.
Crossref
Crossref
Anthony Hardy, Diane Benford, Thorhallur Halldorsson, Michael John Jeger, Helle Katrine Knutsen, Simon More, Hanspeter Naegeli, Hubert Noteborn, Colin Ockleford, Antonia Ricci, Guido Rychen, Josef R Schlatter, Vittorio Silano, Roland Solecki, Dominique Turck, Jean‐Louis Bresson, Birgit Dusemund, Ursula Gundert‐Remy, Mathilde Kersting, Claude Lambré, André Penninks, Angelika Tritscher, Ine Waalkens‐Berendsen, Ruud Woutersen, Davide Arcella, Daniele Court Marques, Jean‐Lou Dorne, George EN Kass & Alicja Mortensen. (2017) Guidance on the risk assessment of substances present in food intended for infants below 16 weeks of age. EFSA Journal 15:5.
Crossref
Crossref
Mariline Gameiro, Renata Silva, Carolina Rocha-Pereira, Helena Carmo, Félix Carvalho, Maria Bastos & Fernando Remião. (2017) Cellular Models and In Vitro Assays for the Screening of modulators of P-gp, MRP1 and BCRP. Molecules 22:4, pages 600.
Crossref
Crossref
R.E. White. 2017. Comprehensive Medicinal Chemistry III. Comprehensive Medicinal Chemistry III
1
33
.
Gl?ria Lozano-Mena, Marta S?nchez-Gonz?lez, Andr?s Parra, M. Em?lia Juan & Joana M. Planas. (2016)
Identification of gut-derived metabolites of maslinic acid, a bioactive compound from
Olea europaea
L
. Molecular Nutrition & Food Research 60:9, pages 2053-2064.
Crossref
Crossref
Sascha C. T. Nicklisch, Steven D. ReesAaron P. McGrathTufan GökirmakLindsay T. BonitoLydia M. VermeerCristina Cregger, Greg LoewenStuart SandinGeoffrey ChangAmro Hamdoun. (2016) Global marine pollutants inhibit P-glycoprotein: Environmental levels, inhibitory effects, and cocrystal structure. Science Advances 2:4.
Crossref
Crossref
C. Roland Wolf, Yury Kapelyukh, Nico Scheer & Colin J. Henderson. 2015. New Horizons in Predictive Drug Metabolism and Pharmacokinetics. New Horizons in Predictive Drug Metabolism and Pharmacokinetics
152
176
.
Dong-Hyun Kim. (2015) Gut Microbiota-Mediated Drug-Antibiotic Interactions. Drug Metabolism and Disposition 43:10, pages 1581-1589.
Crossref
Crossref
Robert S. Foti, Rachel F. Tyndale, Kristine L. P. Garcia, Douglas H. Sweet, Swati Nagar, Satish Sharan & Dan A. Rock. (2015) “Target-Site” Drug Metabolism and Transport. Drug Metabolism and Disposition 43:8, pages 1156-1168.
Crossref
Crossref
Stefanie Grünwald, Janine Niedermeier & Uwe Wenzel. (2014) Hormesis is induced in the red flour beetle Tribolium castaneum through ingestion of charred toast. European Journal of Nutrition 54:4, pages 535-541.
Crossref
Crossref
Marc Le Vee, Elodie Jouan, Bruno Stieger, Valérie Lecureur & Olivier Fardel. (2015) Regulation of Human Hepatic Drug Transporter Activity and Expression by Diesel Exhaust Particle Extract. PLOS ONE 10:3, pages e0121232.
Crossref
Crossref
Chandra Prakash, Baltazar Zuniga, Chung Seog Song, Shoulei Jiang, Jodie Cropper, Sulgi Park & Bandana Chatterjee. (2015) Nuclear Receptors in Drug Metabolism, Drug Response and Drug Interactions. Nuclear Receptor Research 2.
Crossref
Crossref
Sara Epis, Daniele Porretta, Valentina Mastrantonio, Sandra Urbanelli, Davide Sassera, Leone De Marco, Valeria Mereghetti, Matteo Montagna, Irene Ricci, Guido Favia & Claudio Bandi. (2014) Temporal dynamics of the ABC transporter response to insecticide treatment: insights from the malaria vector Anopheles stephensi. Scientific Reports 4:1.
Crossref
Crossref
. (2014) Modern methodologies and tools for human hazard assessment of chemicals. EFSA Journal 12:4.
Crossref
Crossref