Citations (79)
Keep up to date with the latest research on this topic with citation updates for this article.
Read on this site (5)
Jianxin Yang, Xue Bai, Guiqin Liu & Xiangyang Li. (2022) A transcriptional regulatory network of HNF4α and HNF1α involved in human diseases and drug metabolism. Drug Metabolism Reviews 54:4, pages 361-385.
Read now
Read now
Dong Gui Hu, Peter I. Mackenzie, Julie-Ann Hulin, Ross A. McKinnon & Robyn Meech. (2022) Regulation of human UDP-glycosyltransferase (UGT) genes by miRNAs. Drug Metabolism Reviews 54:2, pages 120-140.
Read now
Read now
Farideh Shafiee-Kermani, Skyla T. Carney, Dereje Jima, Utibe C. Utin, LaNeisha B. Farrar, Melvin O. Oputa, Marcono R. Hines, H. Karimi Kinyamu, Kevin W. Trotter, Trevor K. Archer, Cathrine Hoyo, Beverly H. Koller, Stephen J. Freedland & Delores J. Grant. (2021) Expression of UDP Glucuronosyltransferases 2B15 and 2B17 is associated with methylation status in prostate cancer cells. Epigenetics 16:3, pages 289-299.
Read now
Read now
Dong Gui Hu, Peter I. Mackenzie, Ross A. McKinnon & Robyn Meech. (2016) Genetic polymorphisms of human UDP-glucuronosyltransferase (UGT) genes and cancer risk. Drug Metabolism Reviews 48:1, pages 47-69.
Read now
Read now
Zoe Riches & Abby C Collier. (2015) Posttranscriptional regulation of uridine diphosphate glucuronosyltransferases. Expert Opinion on Drug Metabolism & Toxicology 11:6, pages 949-965.
Read now
Read now
Articles from other publishers (74)
Jiahui Cai, Furong Huang, Wenyan Gao, Tongyang Gong, Hongyan Chen & Zhihua Liu. (2023) Androgen Receptor/AP-1 Activates UGT2B15 Transcription to Promote Esophageal Squamous Cell Carcinoma Invasion. Cancers 15:24, pages 5719.
Crossref
Crossref
Lucas Zhou, Abelardo D. Montalvo, Joseph M. Collins & Danxin Wang. (2023) Quantitative analysis of the UDP‐glucuronosyltransferase transcriptome in human tissues. Pharmacology Research & Perspectives 11:6.
Crossref
Crossref
John O. Miners, Thomas M. Polasek, Julie-Ann Hulin, Andrew Rowland & Robyn Meech. (2023) Drug-drug interactions that alter the exposure of glucuronidated drugs: Scope, UDP-glucuronosyltransferase (UGT) enzyme selectivity, mechanisms (inhibition and induction), and clinical significance. Pharmacology & Therapeutics 248, pages 108459.
Crossref
Crossref
Xuedong Gu, Xinping Chang, Lin Yang, Yangzom Chamba & Fang Geng. (2023) Quantitative Proteomic Analysis of Tibetan Pig Livers at Different Altitudes. Molecules 28:4, pages 1694.
Crossref
Crossref
Wenyu Liu, Jing Li, Rui Zhao, Yao Lu & Panpan Huang. (2023) The Uridine diphosphate (UDP)-glycosyltransferases (UGTs) superfamily: the role in tumor cell metabolism. Frontiers in Oncology 12.
Crossref
Crossref
Samuel Amintas, Pauline Beaumont, Charles Dupin, Isabelle Moranvillier, Isabelle Lamrissi, Elie Patel, Benjamin Fernandez, Alice Bibeyran, Julian Boutin, Tristan Richard, Stéphanie Krisa, François Moreau-Gaudry, Aurélie Bedel, David Cappellen, Benoît Pinson, Véronique Vendrely & Sandrine Dabernat. (2022) Differential Uridyl-diphosphate-Glucuronosyl Transferase 1A enzymatic arsenal explains the specific cytotoxicity of resveratrol towards tumor colorectal cells. Journal of Functional Foods 99, pages 105345.
Crossref
Crossref
Dong Gui Hu, Shashikanth Marri, Julie-Ann Hulin, Ross A. McKinnon, Peter I. Mackenzie & Robyn Meech. (2022) The Somatic Mutation Landscape of UDP-Glycosyltransferase (UGT) Genes in Human Cancers. Cancers 14:22, pages 5708.
Crossref
Crossref
Yang Liu, Lanlan Chen, Xiangbo Meng, Shujun Ye & Lianjun Ma. (2022) Identification of Hub Genes in Colorectal Adenocarcinoma by Integrated Bioinformatics. Frontiers in Cell and Developmental Biology 10.
Crossref
Crossref
Mohamed Emam, Albert Caballero-Solares, Xi Xue, Navaneethaiyer Umasuthan, Barry Milligan, Richard G. Taylor, Rachel Balder & Matthew L. Rise. (2022) Gill and Liver Transcript Expression Changes Associated With Gill Damage in Atlantic Salmon (Salmo salar). Frontiers in Immunology 13.
Crossref
Crossref
Michela Cantiello, Monica Carletti, Mery Giantin, Giulia Gardini, Francesca Capolongo, Paolo Cascio, Marianna Pauletto, Flavia Girolami, Mauro Dacasto & Carlo Nebbia. (2022) Induction by Phenobarbital of Phase I and II Xenobiotic-Metabolizing Enzymes in Bovine Liver: An Overall Catalytic and Immunochemical Characterization. International Journal of Molecular Sciences 23:7, pages 3564.
Crossref
Crossref
Alan Talevi & Carolina L. Bellera. 2022. The ADME Encyclopedia. The ADME Encyclopedia
394
400
.
Cui-Lan Meng, Wei Zhao & Dan-Ni Zhong. (2021) Epigenetics and microRNAs in UGT1As. Human Genomics 15:1.
Crossref
Crossref
Xinmei Cai, Bilian Li, Wei Wei, Yanping Guan, Xue Bai, Min Huang, Yaying Huang, Lili Rong, Xingrong Song & Guoping Zhong. (2021) Circulating microRNA-30a-5p, microRNA-101-3p, microRNA-140-3p and microRNA-141-3p as potential biomarkers for dexmedetomidine response in pediatric patients. European Journal of Clinical Pharmacology 77:12, pages 1853-1859.
Crossref
Crossref
Ke Han, Jukun Wang, Kun Qian, Teng Zhao & Yi Zhang. (2021) Establishment of non-small-cell lung cancer risk prediction model based on prognosis-associated ADME genes. Bioscience Reports 41:10.
Crossref
Crossref
Jia Zhu, Wenpei Liu, Meiling Zhang, Lihuan Lu, Hongqiu Pan, Xiaomin He, Nannan Wang, Miaomiao Yang, Honggang Yi & Shaowen Tang. (2021) A validation study of the UGT1A4 rs2011404 variant and the risk of anti‐tuberculosis drug‐induced hepatotoxicity in an Eastern Chinese Han population. Journal of Clinical Pharmacy and Therapeutics 46:5, pages 1288-1294.
Crossref
Crossref
Kyoko Ondo, Motoki Isono, Masataka Nakano, Shiori Hashiba, Tatsuki Fukami & Miki Nakajima. (2021) The N6-methyladenosine modification posttranscriptionally regulates hepatic UGT2B7 expression. Biochemical Pharmacology 189, pages 114402.
Crossref
Crossref
Dong Gui Hu, Peter I. Mackenzie, Julie-Ann Hulin, Ross A. McKinnon & Robyn Meech. (2021)
Circular RNAs of UDP-Glycosyltransferase (
UGT
) Genes Expand the Complexity and Diversity of the UGT Transcriptome
. Molecular Pharmacology 99:6, pages 488-503.
Crossref
Crossref
Jukun Wang, Ke Han, Chao Zhang, Xin Chen, Yu Li, Linzhong Zhu & Tao Luo. (2021)
Identification and validation of
ADME
genes as prognosis and therapy markers for hepatocellular carcinoma patients
. Bioscience Reports 41:5.
Crossref
Crossref
Stefan Paulusch, Sandra Kalthoff, Steffen Landerer, Christian Jansen, Robert Schierwagen, Sabine Klein, Jonel Trebicka & Christian P Strassburg. (2021) Regulation of uridine diphosphate-glucuronosyltransferase 1A expression by miRNA-214-5p and miRNA-486-3p. Epigenomics 13:4, pages 271-283.
Crossref
Crossref
Karl Walter Bock. (2021) Aryl hydrocarbon receptor (AHR), integrating energy metabolism and microbial or obesity-mediated inflammation. Biochemical Pharmacology 184, pages 114346.
Crossref
Crossref
Renjun Yang, Shuyu Liu, Xiaoxing Liang, Nuoya Yin, Linshu Jiang, Yang Zhang & Francesco Faiola. (2021) TBBPA, TBBPS, and TCBPA disrupt hESC hepatic differentiation and promote the proliferation of differentiated cells partly via up-regulation of the FGF10 signaling pathway. Journal of Hazardous Materials 401, pages 123341.
Crossref
Crossref
Alan Talevi & Carolina L. Bellera. 2021. The ADME Encyclopedia. The ADME Encyclopedia
1
8
.
Dong Gui Hu, Peter I. Mackenzie, Pramod C. Nair, Ross A. McKinnon & Robyn Meech. (2020) The Expression Profiles of ADME Genes in Human Cancers and Their Associations with Clinical Outcomes. Cancers 12:11, pages 3369.
Crossref
Crossref
Daniela Pemp, Leo N. Geppert, Claudia Wigmann, Carolin Kleider, René Hauptstein, Katja Schmalbach, Katja Ickstadt, Harald L. Esch & Leane Lehmann. (2020) Influence of breast cancer risk factors and intramammary biotransformation on estrogen homeostasis in the human breast. Archives of Toxicology 94:9, pages 3013-3025.
Crossref
Crossref
Yasuharu Nakanishi, Yasuhiro Uno & Hiroshi Yamazaki. (2020) Regional distributions of UDP-glucuronosyltransferase activities toward estradiol and serotonin in the liver and small intestine of cynomolgus macaques. Drug Metabolism and Pharmacokinetics 35:4, pages 401-404.
Crossref
Crossref
Haeyoung Zhang, Chris Wolford, Abdul Basit, Albert P. Li, Peter W. Fan, Bernard P. Murray, Ryan H. Takahashi, S. Cyrus Khojasteh, Bill J. Smith, Kenneth E. Thummel & Bhagwat Prasad. (2020) Regional Proteomic Quantification of Clinically Relevant Non-Cytochrome P450 Enzymes along the Human Small Intestine. Drug Metabolism and Disposition 48:7, pages 528-536.
Crossref
Crossref
Laure ElensLoralie J. LangmanDennis A. HesselinkStein BerganDirk Jan A.R. MoesMariadelfina MolinaroRaman VenkataramananFlorian Lemaitre. (2020) Pharmacologic Treatment of Transplant Recipients Infected With SARS-CoV-2: Considerations Regarding Therapeutic Drug Monitoring and Drug–Drug Interactions. Therapeutic Drug Monitoring 42:3, pages 360-368.
Crossref
Crossref
Steffen Landerer, Sandra Kalthoff, Stefan Paulusch & Christian P. Strassburg. (2020) A Gilbert syndrome-associated haplotype protects against fatty liver disease in humanized transgenic mice. Scientific Reports 10:1.
Crossref
Crossref
Siqi Feng, Anqi Li, Yi-Chao Zheng & Hong-Min Liu. (2020) Role of Drug-metabolizing Enzymes in Cancer and Cancer Therapy. Current Drug Metabolism 21:1, pages 67-76.
Crossref
Crossref
Eva Hansmann, Elvira Mennillo, Emiko Yoda, Mélanie Verreault, Olivier Barbier, Shujuan Chen & Robert H. Tukey. (2020)
Differential Role of Liver X Receptor (LXR)
α
and LXR
β
in the Regulation of UDP-Glucuronosyltransferase 1A1 in Humanized
UGT1
Mice
. Drug Metabolism and Disposition 48:4, pages 255-263.
Crossref
Crossref
Joanie Vaillancourt, Véronique Turcotte, Patrick Caron, Lyne Villeneuve, Louis Lacombe, Frédéric Pouliot, Éric Lévesque & Chantal Guillemette. (2020) Glucuronidation of Abiraterone and Its Pharmacologically Active Metabolites by UGT1A4, Influence of Polymorphic Variants and Their Potential as Inhibitors of Steroid Glucuronidation. Drug Metabolism and Disposition 48:2, pages 75-84.
Crossref
Crossref
Yasuhiro Uno, Shotaro Uehara, Takashi Inoue, Shu Kawamura, Norie Murayama, Miyu Nishikawa, Shinichi Ikushiro, Erika Sasaki & Hiroshi Yamazaki. (2020) Molecular characterization of functional UDP-glucuronosyltransferases 1A and 2B in common marmosets. Biochemical Pharmacology 172, pages 113748.
Crossref
Crossref
Risto O. Juvonen, Aki T. Heikkinen, Olli Kärkkäinen, Rabia Jehangir, Juhani Huuskonen, Johanna Troberg, Hannu Raunio, Olli T. Pentikäinen & Moshe Finel. (2020) In vitro glucuronidation of 7-hydroxycoumarin derivatives in intestine and liver microsomes of Beagle dogs. European Journal of Pharmaceutical Sciences 141, pages 105118.
Crossref
Crossref
Dong Gui Hu, J.ulie-Ann Hulin, Pramod C. Nair, Alex Z. Haines, Ross A. McKinnon, Peter I. Mackenzie & Robyn Meech. (2019) The UGTome: The expanding diversity of UDP glycosyltransferases and its impact on small molecule metabolism. Pharmacology & Therapeutics 204, pages 107414.
Crossref
Crossref
Yuhua Li, Qiang Meng, Mengbi Yang, Dongyang Liu, Xiangyu Hou, Lan Tang, Xin Wang, Yuanfeng Lyu, Xiaoyan Chen, Kexin Liu, Ai-Ming Yu, Zhong Zuo & Huichang Bi. (2019) Current trends in drug metabolism and pharmacokinetics. Acta Pharmaceutica Sinica B 9:6, pages 1113-1144.
Crossref
Crossref
Daniela Pemp, Carolin Kleider, Katja Schmalbach, René Hauptstein, Leo N. Geppert, Claudia Köllmann, Katja Ickstadt, Peter Eckert, Iva Neshkova, Rafael Jakubietz, Harald L. Esch & Leane Lehmann. (2019) Qualitative and quantitative differences in estrogen biotransformation in human breast glandular and adipose tissues: implications for studies using mammary biospecimens. Archives of Toxicology 93:10, pages 2823-2833.
Crossref
Crossref
Robyn Meech, Dong Gui Hu, Ross A. McKinnon, Siti Nurul Mubarokah, Alex Z. Haines, Pramod C. Nair, Andrew Rowland & Peter I. Mackenzie. (2019) The UDP-Glycosyltransferase (UGT) Superfamily: New Members, New Functions, and Novel Paradigms. Physiological Reviews 99:2, pages 1153-1222.
Crossref
Crossref
Dong Gui Hu, Shashikanth Marri, Ross A. McKinnon, Peter I. Mackenzie & Robyn Meech. (2019) Deregulation of the Genes that Are Involved in Drug Absorption, Distribution, Metabolism, and Excretion in Hepatocellular Carcinoma. Journal of Pharmacology and Experimental Therapeutics 368:3, pages 363-381.
Crossref
Crossref
Kimberly Lapham, Jian Lin, Jonathan Novak, Christine Orozco, Mark Niosi, Li Di, Theunis C. Goosen, Sangwoo Ryu, Keith Riccardi, Heather Eng, Kimberly O. Cameron & Amit S. Kalgutkar. (2018)
6-Chloro-5-[4-(1-Hydroxycyclobutyl)Phenyl]-1
H
-Indole-3-Carboxylic Acid is a Highly Selective Substrate for Glucuronidation by UGT1A1, Relative to
β
-Estradiol
. Drug Metabolism and Disposition 46:12, pages 1836-1846.
Crossref
Crossref
Matthew W. Linakis, Sarah F. Cook, Shaun S. Kumar, Xiaoxi Liu, Diana G. Wilkins, Roger Gaedigk, Andrea Gaedigk, Catherine M. T. Sherwin & John N. van den Anker. (2018) Polymorphic Expression of UGT1A9 is Associated with Variable Acetaminophen Glucuronidation in Neonates: A Population Pharmacokinetic and Pharmacogenetic Study. Clinical Pharmacokinetics 57:10, pages 1325-1336.
Crossref
Crossref
Dong Gui Hu, Julie-Ann Hulin, Dhilushi D. Wijayakumara, Ross A. McKinnon, Peter I. Mackenzie & Robyn Meech. (2018)
Intergenic Splicing between Four Adjacent
UGT
Genes (
2B15, 2B29P2, 2B17, 2B29P1
) Gives Rise to Variant UGT Proteins That Inhibit Glucuronidation via Protein-Protein Interactions
. Molecular Pharmacology 94:3, pages 938-952.
Crossref
Crossref
Karl Walter Bock. (2018) From TCDD-mediated toxicity to searches of physiologic AHR functions. Biochemical Pharmacology 155, pages 419-424.
Crossref
Crossref
Yasuhiro Uno, Rika Takahira, Norie Murayama, Yu Ishii, Yoshinori Ikenaka, Mayumi Ishizuka, Hiroshi Yamazaki & Shinichi Ikushiro. (2018) Molecular and functional characterization of UDP-glucuronosyltransferase 1A in cynomolgus macaques. Biochemical Pharmacology 155, pages 172-181.
Crossref
Crossref
Päivi Hirvensalo, Aleksi Tornio, Mikko Neuvonen, Tuija Tapaninen, Maria Paile-Hyvärinen, Vesa Kärjä, Ville T. Männistö, Jussi Pihlajamäki, Janne T. Backman & Mikko Niemi. (2018) Comprehensive Pharmacogenomic Study Reveals an Important Role of UGT1A3 in Montelukast Pharmacokinetics. Clinical Pharmacology & Therapeutics 104:1, pages 158-168.
Crossref
Crossref
Aziza A. A. Adam, Vincent A. van der Mark, Joanne M. Donkers, Manon E. Wildenberg, Ronald P. J. Oude Elferink, Robert A. F. M. Chamuleau & Ruurdtje Hoekstra. (2018) A practice-changing culture method relying on shaking substantially increases mitochondrial energy metabolism and functionality of human liver cell lines. PLOS ONE 13:4, pages e0193664.
Crossref
Crossref
Dhilushi D. Wijayakumara, Peter I. Mackenzie, Ross A. McKinnon, Dong Gui Hu & Robyn Meech. (2018) Regulation of UDP-Glucuronosyltransferase 2B15 by miR-331-5p in Prostate Cancer Cells Involves Canonical and Noncanonical Target Sites. Journal of Pharmacology and Experimental Therapeutics 365:1, pages 48-59.
Crossref
Crossref
Brandon T. Gufford, Jason D. Robarge, Michael T. Eadon, Hongyu Gao, Hai Lin, Yunlong Liu, Zeruesenay Desta & Todd C. Skaar. (2018) Rifampin modulation of xeno- and endobiotic conjugating enzyme mRNA expression and associated microRNAs in human hepatocytes. Pharmacology Research & Perspectives 6:2, pages e00386.
Crossref
Crossref
Risto O. Juvonen, Sanna Rauhamäki, Sami Kortet, Sanna Niinivehmas, Johanna Troberg, Aleksanteri Petsalo, Juhani Huuskonen, Hannu Raunio, Moshe Finel & Olli T. Pentikäinen. (2018) Molecular Docking-Based Design and Development of a Highly Selective Probe Substrate for UDP-glucuronosyltransferase 1A10. Molecular Pharmaceutics 15:3, pages 923-933.
Crossref
Crossref
Pei Wang, Ya-li Nie, Shu-jie Wang, Lin-lin Yang, Wei-hong Yang, Jiang-feng Li, Xiao-tian Li & Li-rong Zhang. (2018)
Regulation of
UGT1A
expression by miR-298 in human livers from the Han Chinese population and in human cell lines
. Epigenomics 10:1, pages 43-57.
Crossref
Crossref
X. Ding, L. Li, L.S. Van Winkle & Q.-Y. Zhang. 2018. Comprehensive Toxicology. Comprehensive Toxicology
171
193
.
E.A. Lock & D.J. Antoine. 2018. Comprehensive Toxicology. Comprehensive Toxicology
30
55
.
X. Ding & Q-Y. Zhang. 2018. Comprehensive Toxicology. Comprehensive Toxicology
8
44
.
R. Meech, D.-G. Hu, J.O. Miners & P.I. Mackenzie. 2018. Comprehensive Toxicology. Comprehensive Toxicology
468
496
.
G.L. Kedderis. 2018. Comprehensive Toxicology. Comprehensive Toxicology
128
142
.
Adrien Labriet, Elena De Mattia, Erika Cecchin, Éric Lévesque, Derek Jonker, Félix Couture, Angela Buonadonna, Mario D’Andrea, Lyne Villeneuve, Giuseppe Toffoli & Chantal Guillemette. (2017) Improved Progression-Free Survival in Irinotecan-Treated Metastatic Colorectal Cancer Patients Carrying the HNF1A Coding Variant p.I27L. Frontiers in Pharmacology 8.
Crossref
Crossref
Ming Hu, Baojian Wu & Zhongqiu Liu. (2017) Bioavailability of Polyphenols and Flavonoids in the Era of Precision Medicine. Molecular Pharmaceutics 14:9, pages 2861-2863.
Crossref
Crossref
Danyi Lu, Shuai Wang, Qian Xie, Lianxia Guo & Baojian Wu. (2017) Transcriptional Regulation of Human UDP-Glucuronosyltransferase 2B10 by Farnesoid X Receptor in Human Hepatoma HepG2 Cells. Molecular Pharmaceutics 14:9, pages 2899-2907.
Crossref
Crossref
Xueyan Zhou, Ziqiang Zheng, Chang Xu, Juan Wang, Mengjun Min, Yun Zhao, Xi Wang, Yinhan Gong, Jiale Yin, Meng Guo, Dong Guo, Junnian Zheng, Bei Zhang & Xiaoxing Yin. (2017) Disturbance of Mammary UDP-Glucuronosyltransferase Represses Estrogen Metabolism and Exacerbates Experimental Breast Cancer. Journal of Pharmaceutical Sciences 106:8, pages 2152-2162.
Crossref
Crossref
Dhilushi D. Wijayakumara, Peter I. Mackenzie, Ross A. McKinnon, Dong Gui Hu & Robyn Meech. (2017) Regulation of UDP-Glucuronosyltransferases UGT2B4 and UGT2B7 by MicroRNAs in Liver Cancer Cells. Journal of Pharmacology and Experimental Therapeutics 361:3, pages 386-397.
Crossref
Crossref
Daniel Scotcher, Sarah Billington, Jay Brown, Christopher R. Jones, Colin D. A. Brown, Amin Rostami-Hodjegan & Aleksandra Galetin. (2017) Microsomal and Cytosolic Scaling Factors in Dog and Human Kidney Cortex and Application for In Vitro-In Vivo Extrapolation of Renal Metabolic Clearance. Drug Metabolism and Disposition 45:5, pages 556-568.
Crossref
Crossref
Michèle Rouleau, Yannick Audet-Delage, Sylvie Desjardins, Mélanie Rouleau, Camille Girard-Bock & Chantal Guillemette. (2017) Endogenous Protein Interactome of Human UDP-Glucuronosyltransferases Exposed by Untargeted Proteomics. Frontiers in Pharmacology 8.
Crossref
Crossref
Peter I. Mackenzie, Andrew A. Somogyi & John O. Miners. (2017) Advances in drug metabolism and pharmacogenetics research in Australia. Pharmacological Research 116, pages 7-19.
Crossref
Crossref
Karl Walter Bock. (2017) From dioxin toxicity to putative physiologic functions of the human Ah receptor in homeostasis of stem/progenitor cells. Biochemical Pharmacology 123, pages 1-7.
Crossref
Crossref
Ya-li Nie, Hang He, Jiang-feng Li, Xiang-guang Meng, Liang Yan, Pei Wang, Shu-jie Wang, Hong-zheng Bi, Li-rong Zhang & Quan-cheng Kan. (2016) Hepatic expression of transcription factors affecting developmental regulation of UGT1A1 in the Han Chinese population. European Journal of Clinical Pharmacology 73:1, pages 29-37.
Crossref
Crossref
Elizabeth Neumann, Huma Mehboob, Jacqueline Ramírez, Snezana Mirkov, Min Zhang & Wanqing Liu. (2016) Age-Dependent Hepatic UDP-Glucuronosyltransferase Gene Expression and Activity in Children. Frontiers in Pharmacology 7.
Crossref
Crossref
Radim Vrzal, Peter Illes & Zdenek Dvorak. (2016) Transplant drugs affect the expression of phase II and antioxidant enzymes in human carcinoma cells HepG2 but not in primary cultures of human hepatocytes: In vitro comparative study. Pharmacological Reports 68:5, pages 1008-1014.
Crossref
Crossref
Michèle Rouleau, Alan Tourancheau, Camille Girard-Bock, Lyne Villeneuve, Jonathan Vaucher, Anne-Marie Duperré, Yannick Audet-Delage, Isabelle Gilbert, Ion Popa, Arnaud Droit & Chantal Guillemette. (2016) Divergent Expression and Metabolic Functions of Human Glucuronosyltransferases through Alternative Splicing. Cell Reports 17:1, pages 114-124.
Crossref
Crossref
Kathleen M. Knights, Shane M. Spencer, John K. Fallon, Nuy Chau, Philip C. Smith & John O. Miners. (2016)
Scaling factors for the
in vitro
-
in vivo
extrapolation (IV-IVE) of renal drug and xenobiotic glucuronidation clearance
. British Journal of Clinical Pharmacology 81:6, pages 1153-1164.
Crossref
Crossref
Bernhard Uehleke. (2016) Vom Heilfasten zur Detox-Kur: Entwicklung neuer Konzepte zur besseren «Entschlackung». Schweizerische Zeitschrift für Ganzheitsmedizin / Swiss Journal of Integrative Medicine 28:6, pages 324-327.
Crossref
Crossref
Marcelo R Luizon & Nadav Ahituv. (2015) Uncovering drug-responsive regulatory elements. Pharmacogenomics 16:16, pages 1829-1841.
Crossref
Crossref
Dhilushi D. Wijayakumara, Dong Gui Hu, Robyn Meech, Ross A. McKinnon & Peter I. Mackenzie. (2015) Regulation of Human UGT2B15 and UGT2B17 by miR-376c in Prostate Cancer Cell Lines. Journal of Pharmacology and Experimental Therapeutics 354:3, pages 417-425.
Crossref
Crossref
Guillaume Margaillan, Michèle Rouleau, Kathrin Klein, John K. Fallon, Patrick Caron, Lyne Villeneuve, Philip C. Smith, Ulrich M. Zanger & Chantal Guillemette. (2015) Multiplexed Targeted Quantitative Proteomics Predicts Hepatic Glucuronidation Potential. Drug Metabolism and Disposition 43:9, pages 1331-1335.
Crossref
Crossref
Karl Walter Bock. (2015) Roles of human UDP-glucuronosyltransferases in clearance and homeostasis of endogenous substrates, and functional implications. Biochemical Pharmacology 96:2, pages 77-82.
Crossref
Crossref
Dong Gui Hu, Peter I. Mackenzie, Lu Lu, Robyn Meech & Ross A. McKinnon. (2015) Induction of Human UDP-Glucuronosyltransferase 2B7 Gene Expression by Cytotoxic Anticancer Drugs in Liver Cancer HepG2 Cells. Drug Metabolism and Disposition 43:5, pages 660-668.
Crossref
Crossref