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Drug Metabolism Reviews Volume 15, 1984 - Issue 1-2
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Research Article

Estimation of Population Pharmacokinetic Parameters Using Destructively Obtained Experimental Data: A Simulation Study of the One-Compartment Open Model

F. Tom Lindstrom Statistics Department Oregon State, University Corvallis, Oregon, 97331
&
David S. Birkes Statistics Department Oregon State, University Corvallis, Oregon, 97331
Pages 195-264 | Published online: 22 Sep 2008

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Read on this site (3)

C. D. Jones, H. Sun & E. I. Ette. (1996) Designing Cross-Sectional Population Pharmacokinetic Studies: Implications for Pediatric and Animal Studies. Clinical Research and Regulatory Affairs 13:3-4, pages 133-165.
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E. I. Ette, A. W. Kelman, C. A. Howie & B. Whiting. (1994) Influence of Inter-Animal Variability on the Estimation of Population Pharmacokinetic Parameters in Preclinical Studies. Clinical Research and Regulatory Affairs 11:2, pages 121-139.
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Stuart L. Beal. (1984) 1. Population Pharmacokinetic Data and Parameter Estimation Based on Their First Two Statistical Moments. Drug Metabolism Reviews 15:1-2, pages 173-193.
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Articles from other publishers (13)

Peter L. BonatePeter L. Bonate. 2011. Pharmacokinetic-Pharmacodynamic Modeling and Simulation. Pharmacokinetic-Pharmacodynamic Modeling and Simulation 303 358 .
Hui-May Chu & Ene I. Ette. (2005) A random sampling approach for robust estimation of tissue-to-plasma ratio from extremely sparse data. The AAPS Journal 7:1, pages E249-E258.
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Ivan Nestorov. (2003) Whole Body Pharmacokinetic Models. Clinical Pharmacokinetics 42:10, pages 883-908.
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Jeremy P. Hing, Steven G. Woolfrey, Dennis Greenslade & Peter M. C. Wright. (2002) Distinguishing animal subsets in toxicokinetic studies: comparison of non‐linear mixed effects modelling with non‐compartmental methods. Journal of Applied Toxicology 22:6, pages 437-443.
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Meryl E. Wastney, Blossom H. Patterson, Oscar A. Linares, Peter C. Greif & Ray C. Boston. 1999. Investigating Biological Systems Using Modeling. Investigating Biological Systems Using Modeling 257 274 .
Harry Mager & Gernot Göller. (1998) Resampling Methods in Sparse Sampling Situations in Preclinical Pharmacokinetic Studies. Journal of Pharmaceutical Sciences 87:3, pages 372-378.
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D A Beatty & W W Piegorsch. (2016) Optimal statistical design for toxicokinetic studies. Statistical Methods in Medical Research 6:4, pages 359-376.
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J.-L. Steimer, S. Vozeh, A. Racine-Poon, N. Holford & R. O’Neill. 1994. Pharmacokinetics of Drugs. Pharmacokinetics of Drugs 405 451 .
Jerry R. Nedelman, Ekaterina Gibiansky, Francis L. S. Tse & Christine Babiuk. (1993) Assessing drug exposure in rodent toxicity studies without satellite animals. Journal of Pharmacokinetics and Biopharmaceutics 21:3, pages 323-334.
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L. Aarons. (1993) Sparse data analysis. European Journal of Drug Metabolism and Pharmacokinetics 18:1, pages 97-100.
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Thomas M. Ludden, Sandra R. B. Allerheiligen & Raymond F. Burk. (1991) Application of population analysis to physiological pharmacokinetics. Journal of Pharmacokinetics and Biopharmaceutics 19:S3, pages S101-S113.
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LUC P. BALANT, HENK ROSEBOOM & URSULA M. GUNDERT-REMY. 1990. 1 138 .
Paul J. Boor. (1985) Allylamine cardiovascular toxicity: V. tissue distribution and toxicokinetics after oral administration. Toxicology 35:3, pages 167-177.
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